Molecular model of shikimate kinase from Mycobacterium tuberculosis

Biochemical and Biophysical Research Communications

Volumn 295, Issue 1, 2002, Pages 142-148

  Filgueira de Azevedo, Walter ^a,b   Canduri, Fernanda ^a,b   Simões de Oliveira, Jaim ^c   Augusto Basso, Luiz ^c   Sérgio Palma, Mário ^a,b   Henrique Pereira, José ^a   Santiago Santos, Diógenes ^c  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Bioinformatics; Drug design; Mycobacterium tuberculosis; Shikimate kinase; Structure

Indexed keywords

BACTERIAL ENZYME; SHIKIMATE KINASE; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; BINDING SITE; CONTROLLED STUDY; DRUG DESIGN; GENE SEQUENCE; HYDROGEN BOND; MOLECULAR MODEL; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ADENOSINE DIPHOSPHATE; AMINO ACID SEQUENCE; BINDING SITES; HYDROGEN BONDING; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PECTOBACTERIUM CHRYSANTHEMI; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT;

ALGAE; EMBRYOPHYTA; FUNGI; MAMMALIA; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0036304185     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00632-0     Document Type: Article

References (32)

1. Diagnostic standards and classification of tuberculosis in adults and children
2. Resistance to antitubercular drugs
3. The shikimate pathway - A metabolic tree with many branches
4. Nutrition growth and metabolism
5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
6. The three-dimensional structure of shikimate kinase
7. Cloning and overexpression in soluble form of functional shikimate kinase and 5-enolpyruvylshikimate-3-phosphate synthase enzymes from Mycobacterium tuberculosis
8. Comparative protein modelling by satisfaction of spatial restraints
9. Derivation of rules for comparative protein modeling from a database of protein structure alignments
10. Evaluation of comparative protein modeling by MODELLER
11. Modeling mutations and homologous proteins
12. Biochemical and X-ray crystallographic studies on shikimate kinase: The important structural role of the P-loop lysine
13. CHARMM: A program for macromolecular energy minimization and dynamics calculations
14. Calculation of protein conformations by proton-proton distance constraints. A new efficient algorithm
15. Molecular surface recognition: Determination of geometric fit between proteins and their ligands by correlation techniques
16. Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate-3-phosphate synthase in atomic detail
17. Binding of nucleotides by proteins
18. Adenylate kinase motions during catalysis: An energetic counterweight balancing substrate binding
19. Domain closure in adenylate kinase Joints on either side of two helices close like neighboring fingers
20. Distantly related sequences in the α and β subunits of ATP synthase myosin kinases and other ATP-requiring enzymes and a common nucleotide binding fold
21. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
22. Crystal structure of human uropepsin at 2.45 Å resolution
23. Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2 a cell cycle kinase
24. Inhibition of cyclin-dependent kinases by purine analogues: Crystal structure of human CDK2 complexed with roscovitine
25. Molecular model for the binary complex of uropepsin and pepstatin
26. Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol
27. Structural basis for chemical inhibitor of CDK2
28. CLUSTAL V: Improved software for multiple sequence alignment
29. MOLSCRIPT: A program to produce both detailed and schematic plots of proteins