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Volumn 7, Issue 6, 1996, Pages 327-337

Interactions of the human papillomavirus E7 protein with cell cycle regulators

Author keywords

Cell division cycle; Human papillomavirus; Keratinocyte differentiation; Protein degradation; Tumor suppressor protein; Viral oncoprotein

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; DNA; ONCOPROTEIN; REGULATOR PROTEIN; RETINOBLASTOMA PROTEIN; VIRUS PROTEIN;

EID: 0030418318     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1006/scbi.1996.0042     Document Type: Review
Times cited : (84)

References (66)
  • 1
    • 0030577120 scopus 로고    scopus 로고
    • Papillomavirus infections - A major cause of human cancers
    • 1. zur Hausen H (1996) Papillomavirus infections - a major cause of human cancers. Biochim Biophys Acta 1288:F55-F78
    • (1996) Biochim Biophys Acta , vol.1288
    • Zur Hausen, H.1
  • 2
    • 84955718602 scopus 로고
    • International Agency for Research on Cancer/World Health Organization, Lyon, France
    • 2. Organization, IAfRoCWH, Human Papillomaviruses (1995) IARC Monographs on the evaluation of carcinogenic risks to humans, Vol. 64. International Agency for Research on Cancer/World Health Organization, Lyon, France 409
    • (1995) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , vol.64 , pp. 409
  • 3
    • 0026639028 scopus 로고
    • Interactions of HPV E6 and E7 with tumour suppressor gene products
    • 3. Münger K, Scheffner M, Huibregtse JM, Howley PM (1992) Interactions of HPV E6 and E7 with tumour suppressor gene products. Cancer Surv 12:197-217
    • (1992) Cancer Surv , vol.12 , pp. 197-217
    • Münger, K.1    Scheffner, M.2    Huibregtse, J.M.3    Howley, P.M.4
  • 4
    • 0025271203 scopus 로고
    • Association of human papillomavirus types 16 and 18 E6 proteins with p53
    • 4. Werness BA, Levine AJ, Howley PM (1990) Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 248:76-79
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 5
    • 0024535228 scopus 로고
    • The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
    • 5. Dyson N, Howley PM, Münger K, Harlow E (1989) The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243:934-937
    • (1989) Science , vol.243 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Münger, K.3    Harlow, E.4
  • 6
    • 0027166753 scopus 로고
    • The human papillomavirus-E7 protein as a transforming and transactivating factor
    • 6. Münger K, Phelps WC (1993) The human papillomavirus-E7 protein as a transforming and transactivating factor. Biochem Biophys Acta 1155:111-123
    • (1993) Biochem Biophys Acta , vol.1155 , pp. 111-123
    • Münger, K.1    Phelps, W.C.2
  • 9
    • 0026671476 scopus 로고
    • Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation
    • 9. Meyers C, Frattini MG, Hudson JB, Laimins LA (1992) Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation. Science 257:971-973
    • (1992) Science , vol.257 , pp. 971-973
    • Meyers, C.1    Frattini, M.G.2    Hudson, J.B.3    Laimins, L.A.4
  • 10
    • 1842343575 scopus 로고
    • Human papillomavirus type 16 alters human epithelial cell differentiation in vitro
    • 10. McCance DJ, Kopan R, Fuchs E, Laimins LA (1988) Human papillomavirus type 16 alters human epithelial cell differentiation in vitro. Proc Natl Acad Sci USA 85:7169-7173
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7169-7173
    • McCance, D.J.1    Kopan, R.2    Fuchs, E.3    Laimins, L.A.4
  • 11
    • 0026591453 scopus 로고
    • Recombinant retroviruses encoding human papillomavirus type 18 E6 and E7 genes stimulate proliferation and delay differentiation of human keratinocytes early after infection
    • 11. Woodworth CD, Cheng S, Simpson S, Hamacher L, Chow LT, Broker TR, DiPaolo JA (1992) Recombinant retroviruses encoding human papillomavirus type 18 E6 and E7 genes stimulate proliferation and delay differentiation of human keratinocytes early after infection. Oncogene 7:619-626
    • (1992) Oncogene , vol.7 , pp. 619-626
    • Woodworth, C.D.1    Cheng, S.2    Simpson, S.3    Hamacher, L.4    Chow, L.T.5    Broker, T.R.6    DiPaolo, J.A.7
  • 12
    • 0028783782 scopus 로고
    • Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes
    • 12. Cheng S, Schmidt-Grimminger DC, Murant T, Broker TR, Chow LT (1995) Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes. Genes Dev 9:2335-2349
    • (1995) Genes Dev , vol.9 , pp. 2335-2349
    • Cheng, S.1    Schmidt-Grimminger, D.C.2    Murant, T.3    Broker, T.R.4    Chow, L.T.5
  • 13
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • 13. Weinberg RA (1995) The retinoblastoma protein and cell cycle control. Cell 81:323-330
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 14
    • 0026526437 scopus 로고
    • E2F: A link between the rb tumor suppressor protein and viral oncoproteins
    • 14. Nevins JR (1992) E2F: A link between the Rb tumor suppressor protein and viral oncoproteins. Science 258:424-429
    • (1992) Science , vol.258 , pp. 424-429
    • Nevins, J.R.1
  • 15
    • 0024321239 scopus 로고
    • A point mutational analysis of human papillomavirus type 16 E7 protein
    • 15. Edmonds C, Vousden KH (1989) A point mutational analysis of human papillomavirus type 16 E7 protein. J Virol 63:2650-2656
    • (1989) J Virol , vol.63 , pp. 2650-2656
    • Edmonds, C.1    Vousden, K.H.2
  • 16
    • 0025040837 scopus 로고
    • Ability of the HPV16 E7 protein to bind RB and induce DNA synthesis is not sufficient for efficient transforming activity in NIH 3T3 cells
    • 16. Banks L, Edmonds C, Vousden K (1990) Ability of the HPV16 E7 protein to bind RB and induce DNA synthesis is not sufficient for efficient transforming activity in NIH 3T3 cells. Oncogene 5:1383-1389
    • (1990) Oncogene , vol.5 , pp. 1383-1389
    • Banks, L.1    Edmonds, C.2    Vousden, K.3
  • 17
    • 0026597152 scopus 로고
    • Structure-function analysis of the human papillomavirus E7 oncoprotein
    • 17. Phelps WC, Münger K, Yee CL, Barnes JA, Howley PM (1992) Structure-function analysis of the human papillomavirus E7 oncoprotein. J Virol 66:2418-2427
    • (1992) J Virol , vol.66 , pp. 2418-2427
    • Phelps, W.C.1    Münger, K.2    Yee, C.L.3    Barnes, J.A.4    Howley, P.M.5
  • 18
    • 0028076872 scopus 로고
    • A mutational analysis of the amino terminal domain of the human papillomavirus type 16 E7 oncoprotein
    • 18. Brokaw JL, Yee CL, Münger K (1994) A mutational analysis of the amino terminal domain of the human papillomavirus type 16 E7 oncoprotein. Virology 205:603-607
    • (1994) Virology , vol.205 , pp. 603-607
    • Brokaw, J.L.1    Yee, C.L.2    Münger, K.3
  • 19
    • 0027210449 scopus 로고
    • Human papillomavirus type 18 E7 protein requires intact Cys-X-X-Cys motifs for zinc binding, dimerization, and transformation but not for Rb binding
    • 19. McIntyre MC, Frattini MG, Grossman SR, Laimins LA (1993) Human papillomavirus type 18 E7 protein requires intact Cys-X-X-Cys motifs for zinc binding, dimerization, and transformation but not for Rb binding. J Virol 67:3142-3150
    • (1993) J Virol , vol.67 , pp. 3142-3150
    • McIntyre, M.C.1    Frattini, M.G.2    Grossman, S.R.3    Laimins, L.A.4
  • 20
    • 0028793343 scopus 로고
    • Dimerization of the human papillomavirus E7 oncoprotein in vivo
    • 20. Clemens KE, Brent R, Gyuris J, Münger K (1995) Dimerization of the human papillomavirus E7 oncoprotein in vivo. Virology 214:289-293
    • (1995) Virology , vol.214 , pp. 289-293
    • Clemens, K.E.1    Brent, R.2    Gyuris, J.3    Münger, K.4
  • 21
    • 0030033730 scopus 로고    scopus 로고
    • Identification of domains required for transcriptional activation and protein dimerization in the human papillomavirus type-16 E7 protein
    • 21. Zwerschke W, Joswig S, Jansen Durr P (1996) Identification of domains required for transcriptional activation and protein dimerization in the human papillomavirus type-16 E7 protein. Oncogene 12:213-220
    • (1996) Oncogene , vol.12 , pp. 213-220
    • Zwerschke, W.1    Joswig, S.2    Jansen Durr, P.3
  • 22
    • 0026597136 scopus 로고
    • Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes
    • 22. Jewers RJ, Hildebrandt P, Ludlow JW, Kell B, McCance DJ (1992) Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes. J Virol 66:1329-1335
    • (1992) J Virol , vol.66 , pp. 1329-1335
    • Jewers, R.J.1    Hildebrandt, P.2    Ludlow, J.W.3    Kell, B.4    McCance, D.J.5
  • 23
    • 0027411079 scopus 로고
    • The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein
    • 23. Wu EW, Clemens KE, Heck DV, Münger K (1993) The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein. J Virol 67:2402-2407
    • (1993) J Virol , vol.67 , pp. 2402-2407
    • Wu, E.W.1    Clemens, K.E.2    Heck, D.V.3    Münger, K.4
  • 25
    • 0026464656 scopus 로고
    • Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins
    • 25. Dyson N, Guida P, Münger K, Harlow E (1992) Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins. J Virol 66:6893-6902
    • (1992) J Virol , vol.66 , pp. 6893-6902
    • Dyson, N.1    Guida, P.2    Münger, K.3    Harlow, E.4
  • 27
    • 0027380708 scopus 로고
    • Association of the human papillomavirus type 16 E7 protein with the S-phase specific E2F-cyclin A complex
    • 27. Arroyo M, Bagchi S, Raychaudhuri P (1993) Association of the human papillomavirus type 16 E7 protein with the S-phase specific E2F-cyclin A complex. Mol Cell Biol 13:6537-6546
    • (1993) Mol Cell Biol , vol.13 , pp. 6537-6546
    • Arroyo, M.1    Bagchi, S.2    Raychaudhuri, P.3
  • 28
    • 0027523439 scopus 로고
    • Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation
    • 28. Davies R, Hicks R, Crook T, Morris J, Vousden K (1993) Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation. J Virol 67:2521-2528
    • (1993) J Virol , vol.67 , pp. 2521-2528
    • Davies, R.1    Hicks, R.2    Crook, T.3    Morris, J.4    Vousden, K.5
  • 29
    • 0030058803 scopus 로고    scopus 로고
    • Human papillomavirus E7 oncoproteins bind a single form of cyclin E in a complex with cdk2 and p 107
    • 29. McIntyre MC, Ruesch MN, Laimins LA ( 1996) Human papillomavirus E7 oncoproteins bind a single form of cyclin E in a complex with cdk2 and p 107. Virology 215:73-82
    • (1996) Virology , vol.215 , pp. 73-82
    • McIntyre, M.C.1    Ruesch, M.N.2    Laimins, L.A.3
  • 30
    • 0029670376 scopus 로고    scopus 로고
    • Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFβ-treated cells
    • 30. Mal A, Poon RYC, Howe PH, Toyoshima H, Hunter T, Harter ML (1996) Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFβ-treated cells. Nature 380:262-265
    • (1996) Nature , vol.380 , pp. 262-265
    • Mal, A.1    Poon, R.Y.C.2    Howe, P.H.3    Toyoshima, H.4    Hunter, T.5    Harter, M.L.6
  • 31
  • 33
    • 0028331229 scopus 로고
    • Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins
    • 33. White AE, Livanos EM, Tlsty TD (1994) Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes Dev 8:666-667
    • (1994) Genes Dev , vol.8 , pp. 666-667
    • White, A.E.1    Livanos, E.M.2    Tlsty, T.D.3
  • 34
    • 0030941458 scopus 로고    scopus 로고
    • p53, cellular gatekeeper for growth and division
    • 34. Levine AJ (1997) p53, cellular gatekeeper for growth and division. Cell 88:323-331
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 36
    • 0027496935 scopus 로고
    • The p21 CDK-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • 36. Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ (1993) The p21 CDK-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 38
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • 38. Hartwell LH, Kastan MB (1994) Cell cycle control and cancer. Science 266:1821-1828
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 41
    • 0027318205 scopus 로고
    • HPV-16 E7 or adenovirus E1A can overcome the growth arrest of cells immortalized with a temperature-sensitive p53
    • 41. Vousden KH, Vojtesek B, Fisher C, Lane D (1993) HPV-16 E7 or adenovirus E1A can overcome the growth arrest of cells immortalized with a temperature-sensitive p53. Oncogene 8:1697-1702
    • (1993) Oncogene , vol.8 , pp. 1697-1702
    • Vousden, K.H.1    Vojtesek, B.2    Fisher, C.3    Lane, D.4
  • 42
    • 0028325483 scopus 로고
    • Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7
    • 42. Demers GW, Foster SA, Halbert CL, Galloway DA (1994) Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7. Proc Natl Acad Sci USA 91:4382-4386
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4382-4386
    • Demers, G.W.1    Foster, S.A.2    Halbert, C.L.3    Galloway, D.A.4
  • 43
    • 0028239976 scopus 로고
    • Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation
    • 43. Hickman ES, Picksley SM, Vousden KH (1994) Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation. Oncogene 9:2177-2181
    • (1994) Oncogene , vol.9 , pp. 2177-2181
    • Hickman, E.S.1    Picksley, S.M.2    Vousden, K.H.3
  • 44
    • 1842293961 scopus 로고    scopus 로고
    • Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein
    • 44. Jones DL, Münger K (1997) Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein. J Virol 71:2905-2912
    • (1997) J Virol , vol.71 , pp. 2905-2912
    • Jones, D.L.1    Münger, K.2
  • 45
    • 0029815035 scopus 로고    scopus 로고
    • Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation
    • 45. Demers GW, Espling E, Harry JB, Etscheid BG, Galloway DA (1996) Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation. J Virol 70:6862-6869
    • (1996) J Virol , vol.70 , pp. 6862-6869
    • Demers, G.W.1    Espling, E.2    Harry, J.B.3    Etscheid, B.G.4    Galloway, D.A.5
  • 46
    • 0028898424 scopus 로고
    • Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade
    • 46. Scheffner M, Nuber U, Huibregtse JM (1995) Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade. Nature 373:81-83
    • (1995) Nature , vol.373 , pp. 81-83
    • Scheffner, M.1    Nuber, U.2    Huibregtse, J.M.3
  • 47
    • 0029989279 scopus 로고    scopus 로고
    • Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107
    • 47. Stubdal H, Zalvide J, Decaprio JA (1996) Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107. J Virol 70:2781-2788
    • (1996) J Virol , vol.70 , pp. 2781-2788
    • Stubdal, H.1    Zalvide, J.2    Decaprio, J.A.3
  • 48
    • 0029834371 scopus 로고    scopus 로고
    • E7 protein of human papillomavirus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway
    • 48. Boyer SN, Wazer DE, Band V (1996) E7 protein of human papillomavirus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway. Cancer Res 56:4620-4624
    • (1996) Cancer Res , vol.56 , pp. 4620-4624
    • Boyer, S.N.1    Wazer, D.E.2    Band, V.3
  • 49
    • 0026690841 scopus 로고
    • Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins
    • 49. Scheffner M, Münger K, Huibregtse JM, Howley PM (1992) Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins. EMBO J 11:2425-2431
    • (1992) EMBO J , vol.11 , pp. 2425-2431
    • Scheffner, M.1    Münger, K.2    Huibregtse, J.M.3    Howley, P.M.4
  • 50
    • 0025022381 scopus 로고
    • The region of the HPV E7 oncoprotein homologous to adenovirus E1a and SV40 large T antigen contains separate domains for Rb binding and casein kinase II
    • 50. Barbosa MS, Edmonds C, Fisher C, Schiller JT, Lowy DR, Vousden KH (1990) The region of the HPV E7 oncoprotein homologous to adenovirus E1a and SV40 large T antigen contains separate domains for Rb binding and casein kinase II. EMBO J 9:153-160
    • (1990) EMBO J , vol.9 , pp. 153-160
    • Barbosa, M.S.1    Edmonds, C.2    Fisher, C.3    Schiller, J.T.4    Lowy, D.R.5    Vousden, K.H.6
  • 51
    • 0029797841 scopus 로고    scopus 로고
    • Degradation of E2F by the ubiquitin-proteasome pathway: Regulation by retinoblastoma family proteins and adenovirus transforming proteins
    • 51. Hateboer G, Kerkhoven RM, Shvarts A, Bernards R, Beijersbergen RL (1996) Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins. Genes Dev 10:2960-2970
    • (1996) Genes Dev , vol.10 , pp. 2960-2970
    • Hateboer, G.1    Kerkhoven, R.M.2    Shvarts, A.3    Bernards, R.4    Beijersbergen, R.L.5
  • 52
    • 0029820095 scopus 로고    scopus 로고
    • The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
    • 52. Hofmann F, Martelli F, Livingston DM, Wang Z (1996) The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev 10:2949-2959
    • (1996) Genes Dev , vol.10 , pp. 2949-2959
    • Hofmann, F.1    Martelli, F.2    Livingston, D.M.3    Wang, Z.4
  • 53
    • 0028243099 scopus 로고
    • Elevated wild-type p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus type 16 E7 gene
    • 53. Demers GW, Halbert CL, Galloway DA (1994) Elevated wild-type p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus type 16 E7 gene. Virology 198:169-174
    • (1994) Virology , vol.198 , pp. 169-174
    • Demers, G.W.1    Halbert, C.L.2    Galloway, D.A.3
  • 54
    • 0027262606 scopus 로고
    • Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis
    • 54. Lowe SW, Ruley HE (1993) Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev 7:535-545
    • (1993) Genes Dev , vol.7 , pp. 535-545
    • Lowe, S.W.1    Ruley, H.E.2
  • 55
    • 0028334011 scopus 로고
    • Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
    • 55. Pan HC, Griep AE (1994) Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development. Genes Dev 8:1285-1299
    • (1994) Genes Dev , vol.8 , pp. 1285-1299
    • Pan, H.C.1    Griep, A.E.2
  • 56
    • 0028227260 scopus 로고
    • Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
    • 56. Howes KA, Ransom LN, Papermaster DS, Lasudry JGH, Albert DM, Windle JJ (1994) Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes Dev 8:1300-1310
    • (1994) Genes Dev , vol.8 , pp. 1300-1310
    • Howes, K.A.1    Ransom, L.N.2    Papermaster, D.S.3    Lasudry, J.G.H.4    Albert, D.M.5    Windle, J.J.6
  • 57
    • 0029093605 scopus 로고
    • Temporally distinct patterns of p53-dependent and and p53-independent apoptosis during mouse lens development
    • 57. Pan HC, Griep AE (1995) Temporally distinct patterns of p53-dependent and and p53-independent apoptosis during mouse lens development. Genes Dev 9:2157-2169
    • (1995) Genes Dev , vol.9 , pp. 2157-2169
    • Pan, H.C.1    Griep, A.E.2
  • 58
  • 59
    • 0029658030 scopus 로고    scopus 로고
    • The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression
    • 59. Missero C, Di Cunto F, Kiyokawa H, Koff A, Dotto GP (1996) The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. Genes Dev 10:3065-3075
    • (1996) Genes Dev , vol.10 , pp. 3065-3075
    • Missero, C.1    Di Cunto, F.2    Kiyokawa, H.3    Koff, A.4    Dotto, G.P.5
  • 60
    • 0026794206 scopus 로고
    • Functional analysis of human papillomavirus type 16 E7 by complementation with advenovirus E1A mutants
    • 60. Davies RC, Vousden KH (1992) Functional analysis of human papillomavirus type 16 E7 by complementation with advenovirus E1A mutants. J Gen Virol 73:2135-2139
    • (1992) J Gen Virol , vol.73 , pp. 2135-2139
    • Davies, R.C.1    Vousden, K.H.2
  • 62
    • 0029854180 scopus 로고    scopus 로고
    • p300 and CBP as transcriptional regulators and targets of oncogenic events
    • 62. Eckner R (1996) p300 and CBP as transcriptional regulators and targets of oncogenic events. Biol Chem 377:685-688
    • (1996) Biol Chem , vol.377 , pp. 685-688
    • Eckner, R.1
  • 63
    • 0029830342 scopus 로고    scopus 로고
    • Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs
    • 63. Chen PL, Riley DJ, Chen Y, Lee WH (1996) Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. Genes Dev 10:2794-2804
    • (1996) Genes Dev , vol.10 , pp. 2794-2804
    • Chen, P.L.1    Riley, D.J.2    Chen, Y.3    Lee, W.H.4
  • 64
    • 0029960519 scopus 로고    scopus 로고
    • Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in s and G2 phases of the cell cycle
    • 64. Novitch BG, Mulligan GJ, Jacks T, Lassar AB (1996) Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. J Cell Biol 135:441456
    • (1996) J Cell Biol , vol.135 , pp. 441456
    • Novitch, B.G.1    Mulligan, G.J.2    Jacks, T.3    Lassar, A.B.4
  • 65
    • 0030462563 scopus 로고    scopus 로고
    • Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis
    • 65. Janicke RU, Walker PA, Lin XY, Porter AG (1996) Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis. Embo J 15:6969-6978
    • (1996) Embo J , vol.15 , pp. 6969-6978
    • Janicke, R.U.1    Walker, P.A.2    Lin, X.Y.3    Porter, A.G.4
  • 66
    • 0030023846 scopus 로고    scopus 로고
    • Cleavage of retinoblastoma protein during apoptosis: An interleukin 1 beta-converting enzyme-like protease as candidate
    • 66. An B, Dou QP (1996) Cleavage of retinoblastoma protein during apoptosis: An interleukin 1 beta-converting enzyme-like protease as candidate. Cancer Res 56:438-442
    • (1996) Cancer Res , vol.56 , pp. 438-442
    • An, B.1    Dou, Q.P.2


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