Prevention of degenerative diseases; clues from studies investigating oxidative stress, Brussels, 13 November 2002

Mutagenesis

Volumn 18, Issue 5, 2003, Pages 477-483

  Nair, Urmila ^a   Bartsch, Helmut ^a   Nair, Jagadeesan ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALDEHYDE; ANTIOXIDANT; ARACHIDONIC ACID; CATALASE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DNA; GLUTATHIONE PEROXIDASE; LINOLEIC ACID; LIPID; LIPOXYGENASE; MYELOPEROXIDASE; NITRIC OXIDE SYNTHASE; OMEGA 6 FATTY ACID; PEROXIDASE; PLACEBO; PROTEIN P53; RAS PROTEIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; XENOBIOTIC AGENT;

ATHEROGENESIS; BIOCHEMISTRY; CARCINOGENESIS; CARDIOVASCULAR DISEASE; CONFERENCE PAPER; CONTINUING EDUCATION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DNA ADDUCT; DNA DAMAGE; DNA STRAND BREAKAGE; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; EUROPE; EXCISION REPAIR; FOOD INTAKE; FRUIT; GENE MUTATION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GERMANY; HEALTH CARE ORGANIZATION; HUMAN; INFECTION; LIFESTYLE; LIPID PEROXIDATION; MEDICAL RESEARCH; MUTAGENESIS; NEUROLOGIC DISEASE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOGENESIS; PHAGOCYTE; PRIORITY JOURNAL; VEGETABLE;

ANIMALS; ANTIOXIDANTS; CYCLOOXYGENASE 2; DIET; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; HUMANS; ISOENZYMES; LIPID PEROXIDATION; MEMBRANE PROTEINS; MICE; NEURODEGENERATIVE DISEASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; REACTIVE OXYGEN SPECIES;

EID: 0042379797     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/geg009     Document Type: Conference Paper

References (84)

1. Akaike,T., Okamoto,S., Sawa,T., Yoshitake,J., Tamura,F., Ichimori,K., Miyazaki,K., Sasamoto,K. and Maeda,H. (2003) 8-Nitroguanosine formation in viral pneumonia and its implication for pathogenesis. Proc. Natl Acad. Sci. USA, 100, 685-690.
2. Al Tassan,N., Chmiel,N.H., Maynard,J. et al. (2002) Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors. Nature Genet., 30, 227-232.
3. Altman,R., Luciardi,H.L., Muntaner,J., Del Rio,F., Berman,S.G., Lopez,R. and Gonzalez,C. (2002) Efficacy assessment of meloxicam, a preferential cyclooxygenase-2 inhibitor, in acute coronary syndromes without ST-segment elevation: the Nonsteroidal Anti-Inflammatory Drugs in Unstable Angina Treatment-2 (NUT-2) pilot study. Circulation, 106, 191-195.
4. Baik,S.C., Youn,H.S., Chung,M.H., Lee,W.K., Cho,M.J., Ko,G.H., Park,C.K., Kasai,H. and Rhee,K.H. (1996) Increased oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa. Cancer Res., 56, 1279-1282.
5. Barbin,A. (2000) Etheno-adduct-forming chemicals: from mutagenicity testing to tumor mutation spectra. Mutat. Res., 462, 55-69.
6. Bartsch,H., Barbin,A., Marion,M.J., Nair,J. and Guichard,Y. (1994) Formation, detection and role in carcinogenesis of ethenobases in DNA. Drug Metab. Rev., 26, 349-371.
7. Bartsch,H. and Nair,J. (2000) Ultrasensitive and specific detection methods for exocylic DNA adducts: markers for lipid peroxidation and oxidative stress. Toxicology, 153, 105-114.
8. Blaisdell,J.O. and Wallace,S.S. (2001) Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli. Proc. Natl Acad. Sci. USA, 98, 7426-7430.
9. Boiteux,S. and Radicella,J.P. (1999) Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress. Biochimie, 81, 59-67.
10. Boutaud,O., Ou,J.J., Chaurand,P., Caprioli,R.M., Montine,T.J. and Oates,J.A. (2002) Prostaglandin H2 (PGH2) accelerates formation of amyloid beta1-42 oligomers. J. Neurochem., 82, 1003-1006.
11. Cardin,R., Saccoccio,G., Masutti,F., Bellentani,S., Farinati,F. and Tiribelli,C. (2001) DNA oxidative damage in leukocytes correlates with the severity of HCV-related liver disease: validation in an open population study. J. Hepatol., 34, 587-592.
12. Chung,F.L., Chen,H.J. and Nath,R.G. (1996) Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts. Carcinogenesis, 17, 2105-2111.
13. Collins,A.R., Harrington,V., Drew,J. and Melvin,R. (2003) Nutritional modulation of DNA repair in a human intervention study. Carcinogenesis, 24, 511-515.
14. Colussi,C., Parlanti,E., Degan,P. et al. (2002) The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool. Curr. Biol., 12, 912-918.
15. Dušinská,M., Ficek,A., Horska,A. et al. (2001) Glutathione S-transferase polymorphisms influence the level of oxidative DNA damage and antioxidant protection in humans. Mutat. Res., 482, 47-55.
16. Duthie,S.J., Ma,A., Ross,M.A. and Collins,A.R. (1996) Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes. Cancer Res., 56, 1291-1295.
17. ESCODD (2002) Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus. Carcinogenesis, 23, 2129-2133.
18. Esterbauer,H., Schaur,R.J. and Zollner,H. (1991) Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med., 11, 81-128.
19. Forsberg,L., de Faire,U. and Morgenstern,R. (2001) Oxidative stress, human genetic variation and disease. Arch. Biochem. Biophys., 389, 84-93.
20. Furstenberger,G., Marks,F. and Krieg,P. (2002) Arachidonate 8(S)-lipoxygenase. Prostaglandins Other Lipid Mediat., 68/69, 235-243.
21. Gonzalez,C.A., Sala,N. and Capella,G. (2002) Genetic susceptibility and gastric cancer risk. Int. J. Cancer, 100, 249-260.
22. Gros,L., Saparbaev,M.K. and Laval,J. (2002) Enzymology of the repair of free radicals-induced DNA damage. Oncogene, 21, 8905-8925.
23. Hagenlocher,T., Nair,J., Becker,N., Korfmann,A. and Bartsch,H. (2001) Influence of dietary fatty acid, vegetable and vitamin intake on etheno-DNA adducts in white blood cells of healthy female volunteers: a pilot study. Cancer Epidemiol. Biomarkers Prev., 10, 1187-1191.
24. Hardeland,U., Steinacher,R., Jiricny,J. and Schar,P. (2002) Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover. EMBO J., 21, 1456-1464.
25. Hennekens,C.H., Buring,J.E., Manson,J.E. et al. (1996) Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N. Engl. J. Med., 334, 1145-1149.
26. Hong,K.H., Bonventre,J.C., O'Leary,E., Bonventre,J.V. and Lander,E.S. (2001) Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis. Proc. Natl Acad. Sci. USA, 98, 3935-3939.
27. Ischenko,A.A. and Saparbaev,M.K. (2002) Alternative nucleotide incision repair pathway for oxidative DNA damage. Nature, 415, 183-187.
28. Jones,S., Emmerson,P., Maynard,J., Best,J.M., Jordan,S., Williams,G.T., Sampson,J.R. and Cheadle,J.P. (2002) Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C→T:A mutations. Hum. Mol. Genet., 11, 2961-2967.
29. Klungland,A., Hoss,M., Gunz,D., Constantinou,A., Clarkson,S.G., Doetsch,P.W., Bolton,P.H., Wood,R.D. and Lindahl,T. (1999a) Base excision repair of oxidative DNA damage activated by XPG protein. Mol. Cell, 3, 33-42.
30. Klungland,A., Rosewell,I., Hollenbach,S., Larsen,E., Daly,G., Epe,B., Seeberg,E., Lindahl,T. and Barnes,D.E. (1999b) Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc. Natl Acad. Sci. USA, 96, 13300-13305.
31. Kuzminov,A. (2001) Single-strand interruptions in replicating chromosomes cause double-strand breaks. Proc. Natl Acad. Sci. USA, 98, 8241-8246.
32. Laval,J. (1977) Two enzymes are required from strand incision in repair of alkylated DNA. Nature, 269, 829-832.
33. Laval,J., Jurado,J., Saparbaev,M. and Sidorkina,O. (1998) Antimutagenic role of base-excision repair enzymes upon free radical-induced DNA damage. Mutat. Res., 402, 93-102.
34. Le Page,F., Klungland,A., Barnes,D.E., Sarasin,A. and Boiteux,S. (2000a) Transcription coupled repair of 8-oxoguanine in murine cells: the ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences. Proc. Natl Acad. Sci. USA, 97, 8397-8402.
35. Le Page,F., Kwoh,E.E., Avrutskaya,A., Gentil,A., Leadon,S.A., Sarasin,A. and Cooper,P.K. (2000b) Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH and CSB and implications for Cockayne syndrome. Cell, 101, 159-171.
36. Leuratti,C., Watson,M.A., Deag,E.J. et al. (2002) Detection of malondialdehyde DNA adducts in human colorectal mucosa: relationship with diet and the presence of adenomas. Cancer Epidemiol. Biomarkers Prev., 11, 267-273.
37. Marks,F. and Furstenberger,G. (2000) Cancer chemoprevention through interruption of multistage carcinogenesis. The lessons learnt by comparing mouse skin carcinogenesis and human large bowel cancer. Eur. J. Cancer, 36, 314-329.
38. Marnett,L.J. (1999) Chemistry and biology of DNA damage by malondialdehyde. In Singer,B. and Bartsch,H. (eds) Exocyclic DNA Adducts in Mutagenesis and Carcinogenesis, IARC Scientific Publications no. 150. IARC, Lyon, France, pp. 17-27.
39. Marnett,L.J., Wright,T.L., Crews,B.C., Tannenbaum,S.R. and Morrow,J.D. (2000) Regulation of prostaglandin biosynthesis by nitric oxide is revealed by targeted deletion of inducible nitric-oxide synthase. J. Biol. Chem., 275, 13427-13430.
40. Masuda,M., Nishino,H. and Ohshima,H. (2002) Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species. Chem. Biol. Interact., 139, 187-197.
41. Masuda,M., Suzuki,T., Friesen,M.D., Ravanat,J.L., Cadet,J., Pignatelli,B., Nishino,H. and Ohshima,H. (2001) Chlorination of guanosine and other nucleosides by hypochlorous acid and myeloperoxidase of activated human neutrophils. Catalysis by nicotine and trimethylamine. J. Biol. Chem., 276, 40486-40496.
42. McGeer,P.L., McGeer,E.G. and Yasojima,K. (2002) Expression of COX-1 and COX-2 mRNAs in atherosclerotic plaques. Exp. Gerontol., 37, 925-929.
43. McGrath,L.T., McGleenon,B.M., Brennan,S., McColl,D., McILroy,S. and Passmore,A.P. (2001) Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde. Q. J. Med., 94, 485-490.
44. Mitchell,J.H. and Collins,A.R. (1999) Effects of a soy milk supplement on plasma cholesterol levels and oxidative DNA damage in men - a pilot study. Eur. J. Nutr., 38, 143-148.
45. Mitra,S., Izumi,T., Boldogh,I., Bhakat,K.K., Hill,J.W. and Hazra,T.K. (2002) Choreography of oxidative damage repair in mammalian genomes. Free Radic. Biol. Med., 33, 15-28.
46. Muller-Decker,K., Scholz,K., Marks,F. and Furstenberger,G. (1995) Differential expression of prostaglandin H synthase isozymes during multistage carcinogenesis in mouse epidermis. Mol. Carcinog., 12, 31-41.
47. Muller-Decker,K., Kopp-Schneider,A., Marks,F., Seibert,K. and Furstenberger,G. (1998) Localization of prostaglandin H synthase isoenzymes in murine epidermal tumors: suppression of skin tumor promotion by inhibition of prostaglandin H synthase-2. Mol. Carcinog., 23, 36-44.
48. Muller-Decker,K., Neufang,G., Berger,I., Neumann,M., Marks,F. and Furstenberger,G. (2002) Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis. Proc. Natl Acad. Sci. USA, 99, 12483-12488.
49. Muller,K., Siebert,M., Heidt,M., Marks,F., Krieg,P. and Furstenberger,G. (2002) Modulation of epidermal tumor development caused by targeted overexpression of epidermis-type 12S-lipoxygenase. Cancer Res., 62, 4610-4616.
50. 32P-postlabeling. Carcinogenesis, 16, 613-617.
51. Nair,J., Sone,H., Nagao,M., Barbin,A. and Bartsch,H. (1996) Copper-dependent formation of miscoding etheno-DNA adducts in the liver of Long Evans cinnamon (LEC) rats developing hereditary hepatitis and hepatocellular carcinoma. Cancer Res., 56, 1267-1271.
52. Nair,J., Vaca,C.E., Velic,I., Mutanen,M., Valsta,L.M. and Bartsch,H. (1997) High dietary omega-6 polyunsaturated fatty acids drastically increase the formation of etheno-DNA base adducts in white blood cells of female subjects. Cancer Epidemiol. Biomarkers Prev., 6, 597-601.
53. Nair,J., Gal,A., Tamir,S., Tannenbaum,S.R., Wogan,G.N. and Bartsch,H. (1998) Etheno adducts in spleen DNA of SJL mice stimulated to overproduce nitric oxide. Carcinogenesis, 19, 2081-2084.
54. Nair,J., Furstenberger,G., Burger,F., Marks,F. and Bartsch,H. (2000) Promutagenic etheno-DNA adducts in multistage mouse skin carcinogenesis: correlation with lipoxygenase-catalyzed arachidonic acid metabolism. Chem. Res. Toxicol., 13, 703-709.
55. Navasumrit,P., Ward,T.H., O'Connor,P.J., Nair,J., Frank,N. and Bartsch,H. (2001) Ethanol enhances the formation of endogenously and exogenously derived adducts in rat hepatic DNA. Mutat. Res., 479, 81-94.
56. Neufang,G., Furstenberger,G., Heidt,M., Marks,F. and Muller-Decker,K. (2001) Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin. Proc. Natl Acad. Sci. USA, 98, 7629-7634.
57. Omenn,G.S., Goodman,G.E., Thornquist,M.D. et al. (1996) Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N. Engl. J. Med., 334, 1150-1155.
58. Pan,J. and Chung,F.L. (2002) Formation of cyclic deoxyguanosine adducts from omega-3 and omega-6 polyunsaturated fatty acids under oxidative conditions. Chem. Res. Toxicol., 15, 367-372.
59. Parlanti,E., Fortini,P., Macpherson,P., Laval,J. and Dogliotti,E. (2002) Base excision repair of adenine/8-oxoguanine mispairs by an aphidicolin-sensitive DNA polymerase in human cell extracts. Oncogene, 21, 5204-5212.
60. Pascucci,B., Maga,G., Hubscher,U. et al. (2002) Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins. Nucleic Acids Res., 30, 2124-2130.
61. Petruska,J.M., Mosebrook,D.R., Jakab,G.J. and Trush,M.A. (1992) Myeloperoxidase-enhanced formation of (+)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene-DNA adducts in lung tissue in vitro: a role of pulmonary inflammation in the bioactivation of a procarcinogen. Carcinogenesis, 13, 1075-1081.
62. Pool-Zobel,B.L., Bub,A., Muller,H., Wollowski,J. and Rechkemmer,G. (1997) Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods. Carcinogenesis, 18, 1847-1850.
63. Porrini,M. and Riso,P. (2000) Lymphocyte lycopene concentration and DNA protection from oxidative damage is increased in women after a short period of tomato consumption. J. Nutr., 130, 189-192.
64. Pratico,D. and Delanty,N. (2000) Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease. Am. J. Med., 109, 577-585.
65. Pratico,D. and Trojanowski,J.Q. (2000) Inflammatory hypotheses: novel mechanisms of Alzheimer's neurodegeneration and new therapeutic targets? Neurobiol. Aging, 21, 441-445.
66. Privezentzev,C.V., Saparbaev,M. and Laval,J. (2001) The HAP1 protein stimulates the turnover of human mismatch-specific thymine-DNA-glycosylase to process 3,N(4)-ethenocytosine residues. Mutat. Res., 480/481, 277-284.
67. Ratnasinghe,D., Tangrea,J.A., Andersen,M.R., Barrett,M.J., Virtamo,J., Taylor,P.R. and Albanes,D. (2000) Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk. Cancer Res., 60, 6381-6383.
68. Rojas,M., Godschalk,R., Alexandrov,K., Cascorbi,I., Kriek,E., Ostertag,J., van Schooten, F.J. and Bartsch,H. (2001) Myeloperoxidase-463A variant reduces benzo[a]pyrene diol epoxide DNA adducts in skin of coal tar treated patients. Carcinogenesis, 22, 1015-1018.
69. Schmid,K., Nair,J., Winde,G., Velic,I. and Bartsch,H. (2000) Increased levels of promutagenic etheno-DNA adducts in colonic polyps of FAP patients. Int. J. Cancer, 87, 1-4.
70. Shimoda,R., Nagashima,M., Sakamoto,M., Yamaguchi,N., Hirohashi,S., Yokota,J. and Kasai,H. (1994) Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis. Cancer Res., 54, 3171-3172.
71. Sies,H. (1997) Oxidative stress: oxidants and antioxidants. Exp. Physiol., 82, 291-295.
72. 2-Cl-system. Chem. Res. Toxicol., 14, 1163-1169.
73. 2-Cl- system: identification of diimino-imidazole and amino-imidazolone nucleosides. Nucleic Acids Res., 30, 2555-2564.
74. Swenberg,J.A., Bogdanffy,M.S., Ham,A., Holt,S., Kim,A., Morinello,E.J., Ranasinghe,A., Scheller,N. and Upton,P.B. (1999) Formation and repair of DNA adducts in vinyl chloride- and vinyl fluoride-induced carcinogenesis. IARC Scientific Publications no. 150. IARC, Lyon, France, pp. 29-43.
75. Szabo,C. and Ohshima,H. (1997) DNA damage induced by peroxynitrite: subsequent biological effects. Nitric Oxide, 1, 373-385.
76. Takao,M., Kanno,S., Shiromoto,T. et al. (2002) Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols. EMBO J., 21, 3486-3493.
77. Tamir,S., deRojas-Walker,T., Gal,A., Weller,A.H., Li,X., Fox,J.G., Wogan,G.N. and Tannenbaum,S.R. (1995) Nitric oxide production in relation to spontaneous B-cell lymphoma and myositis in SJL mice. Cancer Res., 55, 4391-4397.
78. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group (1994) The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med., 330, 1029-1035.
79. Tsuzuki,T., Egashira,A., Igarashi,H. et al. (2001) Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase. Proc. Natl Acad. Sci. USA, 98, 11456-11461.
80. Weeda,G., de Boer,J., Donker,I., de Wit,J., Winkler,S.B., van der Horst,G.T., Vermeulen,W., Bootsma,D. and Hoeijmakers,J.H. (1998) Molecular basis of DNA repair mechanisms and syndromes. Recent Results Cancer Res., 154, 147-155.
81. Winter,J.P., Gong,Y., Grant,P.J. and Wild,C.P. (2003) Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease. Coron. Artery Dis., 14, 149-153.
82. Yang,I.Y., Johnson,F., Grollman,A.P. and Moriya,M. (2002) Genotoxic mechanism for the major acrolein-derived deoxyguanosine adduct in human cells. Chem. Res. Toxicol., 15, 160-164.
83. Yermilov,V., Rubio,J. and Ohshima,H. (1995) Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination. FEBS Lett., 376, 207-210.
84. Zhang,Y., Chen,S.Y., Hsu,T. and Santella,R.M. (2002) Immunohistochemical detection of malondialdehyde-DNA adducts in human oral mucosa cells. Carcinogenesis, 23, 207-211.