Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk

Cancer Research

Volumn 60, Issue 22, 2000, Pages 6381-6383

  Ratnasinghe, Duminda ^a   Tangrea, Joseph A ^a   Andersen, Mark R ^b   Barrett, Michael J ^c   Virtamo, Jarmo ^d   Taylor, Philip R ^a   Albanes, Demetrius ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ALBANY MOLECULAR RESEARCH INC   (United States)

^c INFORMATION MANAGEMENT SERVICES INC   (United States)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; LEUCINE; PROLINE DERIVATIVE;

ADULT; ARTICLE; CANCER INCIDENCE; CANCER RISK; CODON; CONTROLLED STUDY; DETOXIFICATION; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL;

AGE FACTORS; AGED; ANTIOXIDANTS; BETA CAROTENE; CASE-CONTROL STUDIES; CODON; GENOTYPE; GERM-LINE MUTATION; GLUTATHIONE PEROXIDASE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS; SMOKING; VITAMIN E;

EID: 0033708417     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Genetic polymorphisms of drug-metabolizing enzymes and lung cancer susceptibility
2. Glutathione peroxidase
3. Loss of heterozygosity of the human cytosolic glutathione peroxidase 1 gene in lung cancer
4. Cancer prevention trials in China and Finland
5. The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers
6. α-Tocopherol and β-carotene supplements and lung cancer incidence in the α-tocopherol, β-carotene cancer prevention study: Effects of base-line characteristics and study compliance
7. Nonrandom structural and numerical chromosome changes in non-small cell lung cancer
8. Deletion mapping on the short arm of chromosome 3 in squamous cell carcinoma and adenocarcinoma of the lung
9. Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase. GSHPx-GI
10. Primary structure of human plasma glutathione peroxidase deduced from cDNA sequences
11. Phospholipid hydroperoxide glutathione peroxidase is the 18-kDa selenoprotein expressed in human tumor cell lines
12. Structure and function of the 5'-flanking sequence of the human cytosolic selenium-dependent glutathione peroxidase gene (hgpxl)
13. Post-transcriptional regulation of glutathione peroxidase gene expression by selenium in the HL-60 human myeloid cell line
14. Effect of selenium status on mRNA levels for glutathione peroxidase in rat liver
15. Prediagnostic serum selenium and risk of cancer
16. Serum β-carotene, vitamins A and E, selenium, and the risk of lung cancer
17. Antioxidants and the risk of lung cancer
18. The risk of developing lung cancer associated with antioxidants in the blood: Ascorbic acid, carotenoids, α-tocopherol, selenium, and total peroxyl radical absorbing capacity
19. Serum tocopherols, selenium and lung cancer risk among tin miners in China
20. Relation of radon exposure and tobacco use to lung cancer among tin miners in Yunnan Province, China