Genotoxic mechanism for the major acrolein-derived deoxyguanosine adduct in human cells

Chemical Research in Toxicology

Volumn 15, Issue 2, 2002, Pages 160-164

  Yang, In Young ^a   Johnson, Francis ^b   Grollman, Arthur P ^a   Moriya, Masaaki ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,N 2 (1,3 PROPANO) 2' DEOXYGUANOSINE; 3H 8ALPHA HYDROXY 3 (BETA DEXTRO 2' DEOXYRIBOFURANOSYL) 5,6,7,8 TETRAHYDROPYRIDO[3,2 A]PURIN 9 ONE; 3H 8BETA HYDROXY 3 (BETA DEXTRO 2' DEOXYRIBOFURANOSYL) 5,6,7,8 TETRAHYDROPYRIDO[3,2 A]PURIN 9 ONE; ACROLEIN DERIVATIVE; DEOXYGUANOSINE; DNA; HYDROXYL GROUP; UNCLASSIFIED DRUG;

ARTICLE; BK VIRUS; CONTROLLED STUDY; DNA ADDUCT; DNA SYNTHESIS; GENOTOXICITY; HELA CELL; HUMAN; HUMAN CELL; ISOMER; NUCLEIC ACID BASE SUBSTITUTION; SHUTTLE VECTOR; SIMIAN VIRUS 40; TOXIN STRUCTURE; XERODERMA PIGMENTOSUM;

ACROLEIN; BASE SEQUENCE; DEOXYGUANOSINE; DNA ADDUCTS; DNA DAMAGE; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENS;

BK POLYOMAVIRUS; SIMIAE; SIMIAN VIRUS 40; UNIDENTIFIED SHUTTLE VECTOR;

EID: 0036168646     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx010123c     Document Type: Article

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