Fluid shear stress activates proline-rich tyrosine kinase via reactive oxygen species-dependent pathway

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 22, Issue 11, 2002, Pages 1790-1796

  Tai, Lung Kuo ^a   Okuda, Masanori ^a   Abe, Jun ichi ^a   Yan, Chen ^a   Berk, Bradford C ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Calcium; Proline rich tyrosine kinase; Reactive oxygen species; Shear stress

Indexed keywords

ACETYLCYSTEINE; CALCIUM ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FOCAL ADHESION KINASE; HYDROGEN PEROXIDE; PROLINE; PROLINE RICH TYROSINE KINASE; PROTEIN P130; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; AORTA; ARTICLE; CALCIUM CELL LEVEL; CATTLE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FOCAL ADHESION; IMMUNOPRECIPITATION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SHEAR STRESS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; AORTA; CALCIUM; CATTLE; CELLS, CULTURED; CYTOCHALASIN D; CYTOSKELETAL PROTEINS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; FOCAL ADHESION KINASE 2; HYDROGEN PEROXIDE; OXIDATION-REDUCTION; PHOSPHOLIPASE C; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-CBL; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; RHEOLOGY; SRC-FAMILY KINASES; STRESS, MECHANICAL; SUBSTRATE SPECIFICITY; TIME FACTORS; UBIQUITIN-PROTEIN LIGASES;

EID: 0036847339     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000034475.40227.40     Document Type: Article

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