-
1
-
-
0034705215
-
Platelet APP isoform ratios correlate with declining cognition in AD
-
Baskin F., Rosenberg R.N., Iyer L., Hynan L., Cullum C.M. Platelet APP isoform ratios correlate with declining cognition in AD. Neurology. 54(10):2000;1907-1909.
-
(2000)
Neurology
, vol.54
, Issue.10
, pp. 1907-1909
-
-
Baskin, F.1
Rosenberg, R.N.2
Iyer, L.3
Hynan, L.4
Cullum, C.M.5
-
2
-
-
16944364644
-
Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma
-
Biere A.L., Ostazweski B., Stimson E.R., Hyman B.T., Maggio J.E., Selkoe D.J. Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma. J. Biol. Chem. 271:1996;32916-32922.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32916-32922
-
-
Biere, A.L.1
Ostazweski, B.2
Stimson, E.R.3
Hyman, B.T.4
Maggio, J.E.5
Selkoe, D.J.6
-
3
-
-
18544375622
-
Peripheral blood abnormalities in Alzheimer Disease: Evidence for early endothelial dysfunction
-
Borroni B., Volpi R., Martini G., Del Bono R., Archetti S., Colciaghi F., Akkawi N.M., Di Luca M., Romanelli G., Caimi L., Padovani A. Peripheral blood abnormalities in Alzheimer Disease: evidence for early endothelial dysfunction. Alzh. Dis. Ass. Disorders. 16:2002;150-155.
-
(2002)
Alzh. Dis. Ass. Disorders
, vol.16
, pp. 150-155
-
-
Borroni, B.1
Volpi, R.2
Martini, G.3
Del Bono, R.4
Archetti, S.5
Colciaghi, F.6
Akkawi, N.M.7
Di Luca, M.8
Romanelli, G.9
Caimi, L.10
Padovani, A.11
-
4
-
-
0031754145
-
Alzheimer disease-related abnormalities of amyloid beta precursor protein isoforms in the platelet: The brain's delegate in the periphery?
-
Bush A.I., Tanzi R.E. Alzheimer disease-related abnormalities of amyloid beta precursor protein isoforms in the platelet: the brain's delegate in the periphery? Arch. Neurol. 55(9):1998;1179-1180.
-
(1998)
Arch. Neurol.
, vol.55
, Issue.9
, pp. 1179-1180
-
-
Bush, A.I.1
Tanzi, R.E.2
-
5
-
-
0029100939
-
Platelets are the primary source of amyloid beta-peptide in human blood
-
Chen M., Inestrosa N.C., Ross G.S., Fernandez H.L. Platelets are the primary source of amyloid beta-peptide in human blood. Biochem. Biophys. Res. Commun. 213(1):1995;96-103.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.213
, Issue.1
, pp. 96-103
-
-
Chen, M.1
Inestrosa, N.C.2
Ross, G.S.3
Fernandez, H.L.4
-
6
-
-
0036042518
-
α-Secretase ADAM10 as well as αAPPs is reduced in platelets and CSF of Alzheimer Disease patients
-
Colciaghi F., Borroni B., Pastorino L., Marcello E., Zimmermann M., Cattabeni F.et al. α-Secretase ADAM10 as well as αAPPs is reduced in platelets and CSF of Alzheimer Disease patients. Mol. Med. 8:2002;67-74.
-
(2002)
Mol. Med.
, vol.8
, pp. 67-74
-
-
Colciaghi, F.1
Borroni, B.2
Pastorino, L.3
Marcello, E.4
Zimmermann, M.5
Cattabeni, F.6
-
7
-
-
0033803763
-
Beta amyloid fragments derived from activated platelets deposit in cerebrovascular endothelium: Usage of a novel blood brain barrier endothelial cell model system
-
Davies T.A., Long H.J., Eisenhauer P.B., Hastey R., Cribbs D.H., Fine R.E.et al. Beta amyloid fragments derived from activated platelets deposit in cerebrovascular endothelium: usage of a novel blood brain barrier endothelial cell model system. Amyloid. 7(3):2000;153-165.
-
(2000)
Amyloid
, vol.7
, Issue.3
, pp. 153-165
-
-
Davies, T.A.1
Long, H.J.2
Eisenhauer, P.B.3
Hastey, R.4
Cribbs, D.H.5
Fine, R.E.6
-
8
-
-
0031721665
-
Differential level of platelet amyloid beta precursor protein isoforms: An early marker for Alzheimer disease
-
Di Luca M., Pastorino L., Bianchetti A., Perez J., Vignolo L.A., Lenzi G.L.et al. Differential level of platelet amyloid beta precursor protein isoforms: an early marker for Alzheimer disease. Arch. Neurol. 55(9):1998;1195-1200.
-
(1998)
Arch. Neurol.
, vol.55
, Issue.9
, pp. 1195-1200
-
-
Di Luca, M.1
Pastorino, L.2
Bianchetti, A.3
Perez, J.4
Vignolo, L.A.5
Lenzi, G.L.6
-
9
-
-
0001504829
-
Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo
-
Fassbender K., Simons M., Bergmann C., Stroick M., Lutjohann D., Keller P.et al. Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo. Proc. Natl. Acad. Sci. USA. 98(10):2001;5371-5373.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.10
, pp. 5371-5373
-
-
Fassbender, K.1
Simons, M.2
Bergmann, C.3
Stroick, M.4
Lutjohann, D.5
Keller, P.6
-
10
-
-
0033519601
-
The role of cholesterol in the biosynthesis of beta-amyloid
-
Frears E.R., Stephens D.J., Walters C.E., Davies H., Austen B.M. The role of cholesterol in the biosynthesis of beta-amyloid. Neuroreport. 10(8):1999;1699-1705.
-
(1999)
Neuroreport
, vol.10
, Issue.8
, pp. 1699-1705
-
-
Frears, E.R.1
Stephens, D.J.2
Walters, C.E.3
Davies, H.4
Austen, B.M.5
-
11
-
-
0034214328
-
Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway
-
Galbete J.L., Martin T.R., Peressini E., Modena P., Bianchi R., Forloni G. Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway. Biochem. J. 348:2000;307-313.
-
(2000)
Biochem. J.
, vol.348
, pp. 307-313
-
-
Galbete, J.L.1
Martin, T.R.2
Peressini, E.3
Modena, P.4
Bianchi, R.5
Forloni, G.6
-
12
-
-
0030769091
-
Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides
-
Hartmann T., Bieger S.C., Bruhl B., Tienari P.J., Ida N., Allsop D.et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat. Med. 3(9):1997;1016-1020.
-
(1997)
Nat. Med.
, vol.3
, Issue.9
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.C.2
Bruhl, B.3
Tienari, P.J.4
Ida, N.5
Allsop, D.6
-
13
-
-
0042810567
-
Cholesterol, Aβ and Alzheimer's disease
-
Hartmann T. Cholesterol, Aβ and Alzheimer's disease. TINS. 24:2001;S45-S48.
-
(2001)
TINS
, vol.24
, pp. 45-S48
-
-
Hartmann, T.1
-
14
-
-
0031026879
-
Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam study
-
Hofman A., Ott A., Breteler M.M., Bots M.L., Slooter A.J., van Harskamp F.et al. Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam study. Lancet. 349:1997;151-154.
-
(1997)
Lancet
, vol.349
, pp. 151-154
-
-
Hofman, A.1
Ott, A.2
Breteler, M.M.3
Bots, M.L.4
Slooter, A.J.5
Van Harskamp, F.6
-
15
-
-
0032568843
-
Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol
-
Howland D.S., Trusko S.P., Savage M.J., Reaume A.G., Lang D.M., Hirsch J.D.et al. Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol. J. Biol. Chem. 273(26):1998;16576-16582.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.26
, pp. 16576-16582
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
-
16
-
-
0034638746
-
Statins and the risk of dementia
-
Jick H., Zornberg G.L., Jick S.S., Seshadri S., Drachman D.A. Statins and the risk of dementia. Lancet. 356:2000;1627-1631.
-
(2000)
Lancet
, vol.356
, pp. 1627-1631
-
-
Jick, H.1
Zornberg, G.L.2
Jick, S.S.3
Seshadri, S.4
Drachman, D.A.5
-
17
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10
-
Kojro E., Gimpl G., Lammich S., Marz W., Fahrenholz F. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10. Proc. Natl. Acad. Sci. USA. 98(10):2001;5371-5373.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.10
, pp. 5371-5373
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
Marz, W.4
Fahrenholz, F.5
-
18
-
-
0031746979
-
A detergent-insoluble membrane compartment contains A beta in vivo
-
Lee S.J., Liyanage U., Bickel P.E., Xia W., Lansbury P.T. Jr., Kosik K.S. A detergent-insoluble membrane compartment contains A beta in vivo. Nat. Med. 4(6):1998;730-734.
-
(1998)
Nat. Med.
, vol.4
, Issue.6
, pp. 730-734
-
-
Lee, S.J.1
Liyanage, U.2
Bickel, P.E.3
Xia, W.4
Lansbury P.T., Jr.5
Kosik, K.S.6
-
19
-
-
0033975837
-
Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease
-
Mehta P.D., Pirttila T., Mehta S.P., Sersen E.A., Aisen P.S., Wisnieski H.M. Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease. Arch. Neurol. 57:2000;100-105.
-
(2000)
Arch. Neurol.
, vol.57
, pp. 100-105
-
-
Mehta, P.D.1
Pirttila, T.2
Mehta, S.P.3
Sersen, E.A.4
Aisen, P.S.5
Wisnieski, H.M.6
-
20
-
-
0033591230
-
Cholesterol-dependent generation of a seeding amyloid beta-protein in cell culture
-
Mizuno T., Nakata M., Naiki H., Michikawa M., Wang R., Haass C.et al. Cholesterol-dependent generation of a seeding amyloid beta-protein in cell culture. J. Biol. Chem. 274(21):1999;15110-15114.
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.21
, pp. 15110-15114
-
-
Mizuno, T.1
Nakata, M.2
Naiki, H.3
Michikawa, M.4
Wang, R.5
Haass, C.6
-
21
-
-
0035956515
-
Amyloid precursor protein in platelets: A peripheral marker for the diagnosis of sporadic AD
-
Padovani A., Pastorino L., Borroni B., Colciaghi F., Rozzini L., Monastero R.et al. Amyloid precursor protein in platelets: a peripheral marker for the diagnosis of sporadic AD. Neurology. 57:2001;2243-2248.
-
(2001)
Neurology
, vol.57
, pp. 2243-2248
-
-
Padovani, A.1
Pastorino, L.2
Borroni, B.3
Colciaghi, F.4
Rozzini, L.5
Monastero, R.6
-
22
-
-
0034795651
-
Acyl-coenzyme A: Cholesterol acyltransferase modulates the generation of the amyloid beta-peptide
-
Puglielli L., Konopka G., Pack-Chung E., Ingano L.A., Berezovska O., Hyman B.T.et al. Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide. Nat. Cell Biol. 3(10):2001;905-912.
-
(2001)
Nat. Cell Biol.
, vol.3
, Issue.10
, pp. 905-912
-
-
Puglielli, L.1
Konopka, G.2
Pack-Chung, E.3
Ingano, L.A.4
Berezovska, O.5
Hyman, B.T.6
-
23
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
Refolo L.M., Malester B., LaFrancois J., Bryant-Thomas T., Wang R., Tint G.S.et al. Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol. Dis. 7(4):2000;321-331.
-
(2000)
Neurobiol. Dis.
, vol.7
, Issue.4
, pp. 321-331
-
-
Refolo, L.M.1
Malester, B.2
LaFrancois, J.3
Bryant-Thomas, T.4
Wang, R.5
Tint, G.S.6
-
24
-
-
0035160066
-
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's Disease
-
Refolo L.M., Pappolla M.A., LaFrancois J., Malester B., Schmidt S.D., Thomas-Bryant T.et al. A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's Disease. Neurobiol. Dis. 8(5):2001;890-899.
-
(2001)
Neurobiol. Dis.
, vol.8
, Issue.5
, pp. 890-899
-
-
Refolo, L.M.1
Pappolla, M.A.2
LaFrancois, J.3
Malester, B.4
Schmidt, S.D.5
Thomas-Bryant, T.6
-
25
-
-
0031047350
-
Altered amyloid protein processing in platelets of patients with Alzheimer disease
-
Rosenberg R.N., Baskin F., Fosmire J.A., Risser R., Adams P., Svetlik D.et al. Altered amyloid protein processing in platelets of patients with Alzheimer disease. Arch. Neurol. 54(2):1997;139-144.
-
(1997)
Arch. Neurol.
, vol.54
, Issue.2
, pp. 139-144
-
-
Rosenberg, R.N.1
Baskin, F.2
Fosmire, J.A.3
Risser, R.4
Adams, P.5
Svetlik, D.6
-
26
-
-
0032568552
-
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons
-
Simons M., Keller P., De Strooper B., Beyreuther K., Dotti C.G., Simons K. Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc. Natl. Acad. Sci. USA. 95(11):1998;6460-6464.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.11
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
27
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R., Bennett B.D., Babu-Khan S., Kahn S., Mendiaz E.A., Denis P.et al. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science. 286(5440):1999;735-741.
-
(1999)
Science
, vol.286
, Issue.5440
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
-
28
-
-
0033637408
-
Standardization of measurement of beta-amyloid (1-42) in cerebrospinal fluid and plasma
-
Vanderstichele H., Van Kerschaver E., Hesse C., Davidsson P., Buyse M.A., Andreasen N.et al. Standardization of measurement of beta-amyloid (1-42) in cerebrospinal fluid and plasma. Amyloid. 7:2000;245-258.
-
(2000)
Amyloid
, vol.7
, pp. 245-258
-
-
Vanderstichele, H.1
Van Kerschaver, E.2
Hesse, C.3
Davidsson, P.4
Buyse, M.A.5
Andreasen, N.6
-
29
-
-
0033772113
-
Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
-
Wolozin B., Kellman W., Ruosseau P., Celesia G.G., Siegel G. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch. Neurol. 57(10):2000;1439-1443.
-
(2000)
Arch. Neurol.
, vol.57
, Issue.10
, pp. 1439-1443
-
-
Wolozin, B.1
Kellman, W.2
Ruosseau, P.3
Celesia, G.G.4
Siegel, G.5
-
30
-
-
0035826795
-
A fluid connection: Cholesterol and Abeta1
-
Wolozin B. A fluid connection: cholesterol and Abeta1. Proc. Natl. Acad. Sci. USA. 98(10):2001;5371-5373.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.10
, pp. 5371-5373
-
-
Wolozin, B.1
|