Exposure of rat thymocytes to hydrogen peroxide increases annexin V binding to membranes: Inhibitory actions of deferoxamine and quercetin

European Journal of Pharmacology

Volumn 384, Issue 1, 1999, Pages 47-52

  Oyama, Yasuo ^a   Noguchi, Sachi ^a   Nakata, Mami ^a   Okada, Yoshihiko ^a   Yamazaki, Yuko ^a   Funai, Megumi ^a   Chikahisa, Lumi ^a,b   Kanemaru, Kaori ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b Laboratory of Cancer Research   (Japan)

Author keywords

Annexin V; Ca2+; H2O2; Thymocyte

Indexed keywords

ANNEXIN; CALCIUM ION; DEFEROXAMINE; ETHIDIUM BROMIDE; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LIPOCORTIN 5; PHOSPHATIDYLSERINE; QUERCETIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL MEMBRANE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENCE; MEMBRANE BINDING; MEMBRANE DAMAGE; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; THYMOCYTE;

ANIMALS; ANNEXIN A5; CALCIUM; CELL MEMBRANE; CELL SURVIVAL; CHELATING AGENTS; DEFEROXAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHIDIUM; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENCE; HYDROGEN PEROXIDE; OXIDANTS; PROTEIN BINDING; QUERCETIN; RATS; RATS, WISTAR; THYMUS GLAND;

EID: 0032802394     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00649-4     Document Type: Article

References (26)

1. 2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes. Jpn. J. Pharmacol. 71:1996;299-305.
2. Fadok V.A., Voelker D.R., Campbell P.A., Cohen J.J., Bratton D.L., Henson P.M. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148:1992;2207-2216.
3. Hanasaki Y., Ogawa S., Fukui S. The correlation between active oxygen scavenging and antioxidative effects of flavonoids. Free Radic. Biol. Med. 16:1994;845-850.
4. 2 injury to cultured P388D1 cells. J. Cell. Physiol. 129:1986;356-366.
5. 2+-APTase inhibitor thapsigargin. Exp. Cell. Res. 212:1994;84-92.
6. Kao J.P.Y., Harootunian A.T., Tsien R.Y. Photochemically generated cytosolic calcium pulses and their detection by fluo-3. J. Biol. Chem. 264:1989;8179-8184.
7. Koopman G., Reutelingsperger C.P., Kuijten G.A., Keehnen R.D., Pals S.T., van Oers M.H. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood. 84:1994;1415-1420.
8. Mirabelli F., Salis A., Vairettu M., Bellomo G., Thor H., Orrenious S. Cytoskeltal alterations in human platelets exposed to oxidative stress are mediated by oxidative and Ca-dependent mechanisms. Arch. Biochem. Biophys. 270:1989;478-488.
9. Nakayama T., Yamada M., Osawa T., Kawakishi S. Suppression of active oxygen-induced cytotoxicity by flavonoids. Biochem. Pharmacol. 45:1993;265-267.
10. 2+ concentration and cytotoxicity in hepatocytes exposed to oxidative stress. Toxicology. 52:1988;55-63.
11. 2+ concentration of rat thymocytes. Jpn. J. Pharmacol. 71:1996;273-280.
12. 2+ in toxic cell killing. Trends Pharmacol. Sci. 10:1989;281-285.
13. Oyama Y., Chikahisa L., Ueha T., Hatakeyama Y., Kokubun T. Change in membrane permeability induced by amyloid β protein fragment 25-35 in brain neurons dissociated from rats. Jpn. J. Pharmacol. 68:1995;77-83.
14. Oyama Y., Masuda T., Nakata M., Chikahisa L., Yamazaki Y., Miura K., Okagawa M. Protective actions of 5′-n-alkylated curcumins on living cells suffering from oxidative stress. Eur. J. Pharmacol. 360:1998;65-71.
15. Pellicciari C., Bottone M.G., Biggioera M. Detection of apoptotic cells by annexin V labeling at electron microscopy. Eur. J. Histochem. 41:1997;211-216.
16. Prajda N., Singhal R.L., Yeh Y.A., Olah E., Look K.Y., Weber G. Linkage of reduction in 1-phosphatidylinositol 4-kinase and inositol 1,4,5-triphosphate concentration in human ovarian carcinoma cells treated with quercetin. Life Sci. 56:1995;1587-1593.
17. Rego A.C., Durte E.P., Oliveira C.R. Oxidative stress in acidic conditions increases the production of inositol phosphates in chick retinal cells in culture. Free Radic. Biol. Med. 20:1996;175-187.
18. Shen F., Weber G. Synergistic action of quercetin and genistein in human ovarian carcinoma cells. Oncol. Res. 9:1997;597-602.
19. 2 on contraction and myoplasmic free calcium concentrations in isolated myocardial muscle cells. Biochem. Med. Metab. Biol. 38:1987;195-204.
20. Squier M.K., Miller A.C., Malkinson A.M., Cohen J.J. Calpain activation in apoptosis. J. Cell. Physiol. 59:1994;229-237.
21. Starke P.E., Hoek J.B., Farber J.L. Calcium-dependent and calcium-independent mechanisms of irreversible cell injury in cultured hepatocytes. J. Biol. Chem. 261:1986;3006-3012.
22. Stuart M.C., Damoiseaux J.G., Frederik P.M., Arends J.W., Reuteligsperger C.P. Surface exposure of phosphatidylserine during apoptosis of rat thymocytes precedes nuclear changes. Eur. J. Cell. Biol. 76:1998;77-83.
23. 2-induced renal tubular cell injury. Am. J. Physiol. 263:1992;F214-F221.
24. Verhoven B., Schlegel R.A., Williamson P. Mechanism of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes. J. Exp. Med. 182:1995;1597-1601.
25. Vermes J., Haanen C., Steffens-Nakken H., Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J. Immunol. Methods. 184:1995;39-51.
26. Yokoo T., Kitamura M. Unexpected production of glomerular mesangial cells from oxidant-triggered apoptosis by bioflavonoid quercetin. Am. J. Physiol. 273:1997;F206-F212.