-
1
-
-
0028077099
-
Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
-
Vaziri, H., Dragowska, W., Allsopp, R. C., Thomas, T. E., Harley, C. B., and Lansdorp, P. M. Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. Proc. Natl. Acad. Sci. USA, 91: 9857-9860, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allsopp, R.C.3
Thomas, T.E.4
Harley, C.B.5
Lansdorp, P.M.6
-
2
-
-
0029958047
-
Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA
-
Autexier, C., Pruzan, R., Funk, W. D., and Greider, C. W. Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA. EMBO J., 15: 5928-5935, 1996.
-
(1996)
EMBO J.
, vol.15
, pp. 5928-5935
-
-
Autexier, C.1
Pruzan, R.2
Funk, W.D.3
Greider, C.W.4
-
3
-
-
0034006777
-
Role of telomerase in cell senescence and oncogenesis
-
Urquidi, V., Tarin, D., and Goodison, S. Role of telomerase in cell senescence and oncogenesis. Annu. Rev. Med., 51: 65-79, 2000.
-
(2000)
Annu. Rev. Med.
, vol.51
, pp. 65-79
-
-
Urquidi, V.1
Tarin, D.2
Goodison, S.3
-
4
-
-
0030812868
-
Telomerase activity and its inhibition in benign and malignant breast lesions
-
Sugino, T., Yoshida, K., Bolodeoku, J., Tarin, D., and Goodison, S. Telomerase activity and its inhibition in benign and malignant breast lesions. J. Pathol., 183: 57-61, 1997.
-
(1997)
J. Pathol.
, vol.183
, pp. 57-61
-
-
Sugino, T.1
Yoshida, K.2
Bolodeoku, J.3
Tarin, D.4
Goodison, S.5
-
5
-
-
0030819894
-
Telomerase catalytic subunit homologues from fission yeast and human
-
Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B., and Cech, T. R. Telomerase catalytic subunit homologues from fission yeast and human. Science, 277: 955-959, 1997.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Harley, C.B.7
Cech, T.R.8
-
6
-
-
0030745448
-
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
-
Meyerson, M., Counter, C. M., Eaton, E. N., Ellisen, L. W., Steiner, P., Caddlc, S. D., Ziaugra, L., Beijersbergen, R. L., Davidoff, M. J., Liu, Q., Bacchetti, S., Haber, D. A., and Weinberg, R. A. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell, 90: 785-795, 1997.
-
(1997)
Cell
, vol.90
, pp. 785-795
-
-
Meyerson, M.1
Counter, C.M.2
Eaton, E.N.3
Ellisen, L.W.4
Steiner, P.5
Caddlc, S.D.6
Ziaugra, L.7
Beijersbergen, R.L.8
Davidoff, M.J.9
Liu, Q.10
Bacchetti, S.11
Haber, D.A.12
Weinberg, R.A.13
-
7
-
-
0032567967
-
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
-
Vaziri, H. and Benchimol, S. Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr Biol., 8: 279-282, 1998.
-
(1998)
Curr. Biol.
, vol.8
, pp. 279-282
-
-
Vaziri, H.1
Benchimol, S.2
-
8
-
-
0010045614
-
Extension of life span by introduction of telomerase into normal human cells
-
Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C. P., Morin, G. B., Harley, C. B., Shay, J. W., Lichtsteiner, S., and Wright, W. E. Extension of life span by introduction of telomerase into normal human cells. Science, 279: 349-352, 1998.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
9
-
-
0031230933
-
Developmental regulation of telomerase activity in human fetal tissues during gestation
-
Ulaner, G. A. and Giudice, L. C. Developmental regulation of telomerase activity in human fetal tissues during gestation. Mol. Hum. Reprod., 3: 769-773, 1997.
-
(1997)
Mol. Hum. Reprod.
, vol.3
, pp. 769-773
-
-
Ulaner, G.A.1
Giudice, L.C.2
-
10
-
-
0032530136
-
Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts
-
Ulaner, G. A., Hu, J. F., Vu, T. H., Giudice, L. C., and Hoffman, A. R. Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts. Cancer Res., 58: 4168-4172, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 4168-4172
-
-
Ulaner, G.A.1
Hu, J.F.2
Vu, T.H.3
Giudice, L.C.4
Hoffman, A.R.5
-
11
-
-
0035811032
-
Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation
-
Pendino, F., Flexor, M., Delhommeau, F., Buet, D., Lanotte, M., and Segal-Bendirdjian, E. Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation. Proc. Natl. Acad. Sci. USA, 98: 6662-6667, 2001.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6662-6667
-
-
Pendino, F.1
Flexor, M.2
Delhommeau, F.3
Buet, D.4
Lanotte, M.5
Segal-Bendirdjian, E.6
-
12
-
-
0033036788
-
Suppression of telomerase reverse transcriptase (hTERT) expression in differentiated HL-60 cells: Regulatory mechanisms
-
Xu, D., Gruber, A., Bjorkholm, M., Petersori, C., and Pisa, P. Suppression of telomerase reverse transcriptase (hTERT) expression in differentiated HL-60 cells: regulatory mechanisms. Br. J. Cancer, 80: 1156-1161, 1999.
-
(1999)
Br. J. Cancer
, vol.80
, pp. 1156-1161
-
-
Xu, D.1
Gruber, A.2
Bjorkholm, M.3
Petersori, C.4
Pisa, P.5
-
13
-
-
0035957406
-
Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL 60 cells
-
Xu, D., Popov, N., Hou, M., Wang, Q., Bjorkholm, M., Gruber, A., Menkel, A. R., and Henriksson, M., Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. Proc. Natl. Acad. Sci. USA. 98: 3826-3831, 2001.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3826-3831
-
-
Xu, D.1
Popov, N.2
Hou, M.3
Wang, Q.4
Bjorkholm, M.5
Gruber, A.6
Menkel, A.R.7
Henriksson, M.8
-
14
-
-
0035933748
-
Mechanism for the reduction of telomerase expression during muscle cell differentiation
-
Nozawa, K., Maehara, K., and Isobe, K. Mechanism for the reduction of telomerase expression during muscle cell differentiation. J. Biol. Chem., 276: 22016-22023, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22016-22023
-
-
Nozawa, K.1
Maehara, K.2
Isobe, K.3
-
15
-
-
0034947881
-
E box-dependent activation of telomerase by human papillomavirus type 16 E6 does not require induction of c-myc
-
Gewin, L. and Galloway, D. A. E box-dependent activation of telomerase by human papillomavirus type 16 E6 does not require induction of c-myc. J. Virol., 75: 7198-7201, 2001.
-
(2001)
J. Virol.
, vol.75
, pp. 7198-7201
-
-
Gewin, L.1
Galloway, D.A.2
-
16
-
-
0025333416
-
12-O-tetradecanoylphorbol-13-acetate-induced differentiation of a human rhabdomyosarcoma cell line
-
Aguanno, S., Bouche, M., Adamo, S., and Molinaro, M. 12-O-tetradecanoylphorbol-13-acetate-induced differentiation of a human rhabdomyosarcoma cell line. Cancer Res., 50: 3377-3382, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 3377-3382
-
-
Aguanno, S.1
Bouche, M.2
Adamo, S.3
Molinaro, M.4
-
17
-
-
0029061513
-
Rapid activation and down-regulation of protein kinase C α in 12-O-tetradecanoylphorbol-13-acetate-induced differentiation of human rhabdomyosarcoma cells
-
Bouche, M., Zappelli, F., Polimeni, M., Adamo, S., Wetsel, W. C., Senni, M. I., and Molinaro, M. Rapid activation and down-regulation of protein kinase C α in 12-O-tetradecanoylphorbol-13-acetate-induced differentiation of human rhabdomyosarcoma cells. Cell Growth Differ., 6: 845-852, 1995.
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 845-852
-
-
Bouche, M.1
Zappelli, F.2
Polimeni, M.3
Adamo, S.4
Wetsel, W.C.5
Senni, M.I.6
Molinaro, M.7
-
18
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L., Coviello, G. M., Wright, W. E., Weinrich, S. L., and Shay, J. W. Specific association of human telomerase activity with immortal cells and cancer. Science, 266: 2011-2015, 1994.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
19
-
-
0029590104
-
Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins
-
Molkentin, J. D., Black, B. L., Martin, J. F., and Olson, E. N. Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins. Cell, 83: 1125-1136, 1995.
-
(1995)
Cell
, vol.83
, pp. 1125-1136
-
-
Molkentin, J.D.1
Black, B.L.2
Martin, J.F.3
Olson, E.N.4
-
20
-
-
0032962953
-
The human telomerase catalytic subunit hTERT: Organization of the gene and characterization of the promoter
-
Cong, Y. S., Wen, J., and Bacchetti, S. The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter. Hum. Mol. Genet., 8: 137-142, 1999.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 137-142
-
-
Cong, Y.S.1
Wen, J.2
Bacchetti, S.3
-
21
-
-
0033558281
-
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene
-
Horikawa, I., Cable, P. L., Afshari, C., and Barrett, J. C. Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene. Cancer Res., 59: 826-830, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 826-830
-
-
Horikawa, I.1
Cable, P.L.2
Afshari, C.3
Barrett, J.C.4
-
22
-
-
0027408096
-
Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity
-
Ayer, D. E., Kretzner, L., and Eisenman, R. N. Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity. Cell, 72: 211-222, 1993.
-
(1993)
Cell
, vol.72
, pp. 211-222
-
-
Ayer, D.E.1
Kretzner, L.2
Eisenman, R.N.3
-
23
-
-
0030922545
-
Transcriptional control. Sinful repression
-
Wolffe, A. P. Transcriptional control. Sinful repression. Nature. 387: 16-17, 1997.
-
(1997)
Nature
, vol.387
, pp. 16-17
-
-
Wolffe, A.P.1
-
24
-
-
0034680840
-
Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells
-
Cong, Y. S. and Bacchetti, S. Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells. J. Biol. Chem., 275: 35665-35668, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35665-35668
-
-
Cong, Y.S.1
Bacchetti, S.2
-
25
-
-
0033568920
-
AP2α and AP2γ: A comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs
-
McPherson, L. A. and Weigel, R. J. AP2α and AP2γ: a comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs. Nucleic Acids Res., 27: 4040-4049, 1999.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 4040-4049
-
-
McPherson, L.A.1
Weigel, R.J.2
-
26
-
-
0008592660
-
c-Myc mediated regulation of telomerase activity is disabled in immortalized cells
-
Drissi, R., Zindy, F., Roussel, M. F., and Cleveland, J. L. c-Myc mediated regulation of telomerase activity is disabled in immortalized cells. J. Biol. Chem., 11: 11, 2001.
-
(2001)
J. Biol. Chem.
, vol.11
, pp. 11
-
-
Drissi, R.1
Zindy, F.2
Roussel, M.F.3
Cleveland, J.L.4
-
27
-
-
0033082526
-
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
-
Takakura, M., Kyo, S., Kanaya, T., Hirano, H., Takeda, J., Yutsudo, M., and Inoue, M. Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res., 59: 551-557, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 551-557
-
-
Takakura, M.1
Kyo, S.2
Kanaya, T.3
Hirano, H.4
Takeda, J.5
Yutsudo, M.6
Inoue, M.7
-
28
-
-
0033604582
-
Function of the c-MyC oncogenic transcription factor
-
Dang, C. V., Resar, L. M., Emison, E., Kim, S., Li, Q., Prescott, J. E., Wonsey, D., and Zeller, K. Function of the c-MyC oncogenic transcription factor. Exp. Cell Res., 253: 63-77, 1999.
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 63-77
-
-
Dang, C.V.1
Resar, L.M.2
Emison, E.3
Kim, S.4
Li, Q.5
Prescott, J.E.6
Wonsey, D.7
Zeller, K.8
-
29
-
-
0031835432
-
RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2
-
Batsche, E., Muchardt, C., Behrens, J., Hurst, H. C., and Cremisi, C. RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2. Mol. Cell. Biol., 18: 3647-3658, 1998.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3647-3658
-
-
Batsche, E.1
Muchardt, C.2
Behrens, J.3
Hurst, H.C.4
Cremisi, C.5
-
30
-
-
0028949627
-
Transcriptional activation by Myc is under negative control by the transcription factor AP-2
-
Gaubatz, S., Imhof, A., Dosch, R., Werner, O., Mitchell, P., Buettner, R., and Eilers, M. Transcriptional activation by Myc is under negative control by the transcription factor AP-2. EMBO J., 14: 1508-1519, 1995.
-
(1995)
EMBO J.
, vol.14
, pp. 1508-1519
-
-
Gaubatz, S.1
Imhof, A.2
Dosch, R.3
Werner, O.4
Mitchell, P.5
Buettner, R.6
Eilers, M.7
-
31
-
-
0029761161
-
Selective inhibition of telomerase activity during terminal differentiation of immortal cell lines
-
Bestilny, L. J., Brown, C. B., Miura, Y., Robertson, L. D., and Riabowol, K. T. Selective inhibition of telomerase activity during terminal differentiation of immortal cell lines. Cancer Res., 56: 3796-3802, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 3796-3802
-
-
Bestilny, L.J.1
Brown, C.B.2
Miura, Y.3
Robertson, L.D.4
Riabowol, K.T.5
-
32
-
-
0029973653
-
Regulation of telomerase activity in immortal cell lines
-
Holt, S. E., Wright, W. E., and Shay, J. W. Regulation of telomerase activity in immortal cell lines. Mol. Cell. Biol., 16: 2932-2939, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2932-2939
-
-
Holt, S.E.1
Wright, W.E.2
Shay, J.W.3
-
33
-
-
0040708578
-
Myogenesis and MyoD down-regulate Sp1. A mechanism for the repression of GLUT1 during muscle cell differentiation
-
Vinals, F., Fandos, C., Santalucia, T., Ferre, J., Testar, X., Palacin, M., and Zorzano, A. Myogenesis and MyoD down-regulate Sp1. A mechanism for the repression of GLUT1 during muscle cell differentiation. J. Biol. Chem., 272: 12913-12921, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12913-12921
-
-
Vinals, F.1
Fandos, C.2
Santalucia, T.3
Ferre, J.4
Testar, X.5
Palacin, M.6
Zorzano, A.7
-
34
-
-
0037024371
-
Variant forms of upstream stimulatory factors (USFS) control the promoter activity of hTERT,the human gene encoding the catalytic subunit of telomerase
-
Yago, M., Ohki, R., Hatakeyama, S., Fujita, T., and Ishikawa, F., Variant forms of upstream stimulatory factors (USFS) control the promoter activity of hTERT,the human gene encoding the catalytic subunit of telomerase. FEBS Lett., 520: 40-46, 2002.
-
(2002)
FEBS Lett.
, vol.520
, pp. 40-46
-
-
Yago, M.1
Ohki, R.2
Hatakeyama, S.3
Fujita, T.4
Ishikawa, F.5
-
35
-
-
0033518124
-
DNA binding of USF is required for specific E-box dependent gene activation in vivo
-
Kiermaier, A., Gawn, J. M., Desbarats, L., Saffrich, R., Ansorge, W., Farrell, P. J., Eilers, M., and Packham, G. DNA binding of USF is required for specific E-box dependent gene activation in vivo. Oncogene, 18: 7200-7211, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 7200-7211
-
-
Kiermaier, A.1
Gawn, J.M.2
Desbarats, L.3
Saffrich, R.4
Ansorge, W.5
Farrell, P.J.6
Eilers, M.7
Packham, G.8
-
36
-
-
0032946220
-
Cell-type-dependent activity of the ubiquitous transcription factor USF in cellular proliferation and transcriptional activation
-
Qyang, Y., Luo, X., Lu, T., Ismail, P. M., Krylov, D., Vinson, C., and Sawadogo M. Cell-type-dependent activity of the ubiquitous transcription factor USF in cellular proliferation and transcriptional activation. Mol. Cell. Biol., 19: 1508-1517, 1999.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1508-1517
-
-
Qyang, Y.1
Luo, X.2
Lu, T.3
Ismail, P.M.4
Krylov, D.5
Vinson, C.6
Sawadogo, M.7
-
37
-
-
0030052039
-
Antiproliferative properties of the USF family of helix-loop-helix transcription factors
-
Luo, X. and Sawadogo, M. Antiproliferative properties of the USF family of helix-loop-helix transcription factors. Proc. Natl. Acad. Sci. USA, 93: 1308-1313, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1308-1313
-
-
Luo, X.1
Sawadogo, M.2
-
38
-
-
0034142386
-
Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT)
-
Kyo, S., Takakura, M., Taira, T., Kanaya, T., Itoh, H., Yutsudo, M., Ariga, H., and Inoue, M. Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT). Nucleic Acids Res., 28: 669-677, 2000.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 669-677
-
-
Kyo, S.1
Takakura, M.2
Taira, T.3
Kanaya, T.4
Itoh, H.5
Yutsudo, M.6
Ariga, H.7
Inoue, M.8
-
39
-
-
0034490210
-
Telomerase activity in soft-tissue and bone sarcomas
-
Aogi, K., Woodman, A., Urquidi, V., Mangham, D. C., Tarin, D., and Goodison, S. Telomerase activity in soft-tissue and bone sarcomas. Clin. Cancer Res., 6: 4776-4781, 2000.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 4776-4781
-
-
Aogi, K.1
Woodman, A.2
Urquidi, V.3
Mangham, D.C.4
Tarin, D.5
Goodison, S.6
|