Alternative splicing of the fibronectin EIIIB exon depends on specific TGCATG repeats

Molecular and Cellular Biology

Volumn 18, Issue 7, 1998, Pages 3900-3906

  Lim, Lee P ^b   Sharp, Phillip A ^a,b  

^a Massachusetts Inst of Technology ^*  (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN;

ALTERNATIVE RNA SPLICING; ARTICLE; EXON; GENE SEQUENCE; INTRON; MOLECULAR EVOLUTION; NONHUMAN; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TANDEM REPEAT; XENOPUS LAEVIS;

VERTEBRATA; XENOPUS LAEVIS;

EID: 0031806710     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.7.3900     Document Type: Article

References (38)

1. Ayane, M., U. Preuss, G. Kohler, and P. Nielsen. 1991. A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs. Nucleic Acids Res. 19:1273-1278.
2. Barone, M., C. Henchcliffe, F. Baralle, and G. Paolella. 1989. Cell type specific trans-acting factors are involved in alternative splicing of human fibronectin pre-mRNA. EMBO J. 8:1079-1085.
3. Black, D. Personal communication.
4. Caceres, J., S. Stamm, D. Helfman, and A. Krainer. 1994. Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors. Science 265:1706-1709.
5. Caputi, M., G. Casari, S. Guenzi, R. Tagliabue, A. Sidoli, C. Melo, and F. Baralle. 1994. A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon. Nucleic Acids Res. 22:1018-1022.
6. Caputi, M., C. Melo, and F. Baralle, 1995. Regulation of fibronectin expression in rat regenerating liver. Nucleic Acids Res. 23:238-243.
7. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroforrn extraction. Anal. Biochem. 162:156-159.
8. DeSimone, D., P. Norton, and R. Hynes. 1992. Identification and characterization of alternatively spliced fibronectin mRNAs expressed in early Xenopus embryos. Dev. Biol. 149:357-369.
9. Diamond, R., K. Du, V. Lee, K. Mohn, B. Haber, D. Tewari, and R. Taub. 1993. Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing. J. Biol. Chem. 268:15185-15192.
10. Du, K., Y. Peng, L. Greenbaum, B. Haber, and R. Taub. 1997. HRS/SRp40-mediated inclusion of the fibronectin EIIIB exon, a possible cause of increased EIIIB expression in proliferating liver. Mol. Cell. Biol. 17:4096-4104.
11. Ffrench-Constant, C., and R. O. Hynes. 1989. Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo. Development 106:375-388.
12. Ffrench-Constant, C. 1995. Alternative splicing of fibronectin - many different proteins but few different functions. Exp. Cell Res. 221:261-271.
13. Fu, X. 1995. The superfamily of arginine/serine-rich splicing factors. RNA 1:663-680.
14. Gatto, F. D., A. Plet, M. Gesnel, C. Fort, and R. Breathnach. 1997. Multiple interdependent sequence elements control splicing of a fibroblast growth factor receptor 2 alternative exon. Mol. Cell. Biol. 17:5106-5116.
15. Ge, H., and J. Manley. 1990. A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell 62:25-34.
16. Gehris, A., S. Oberlender, K. Shepley, R. Tuan, and V. Bennett. 1996. Fibronectin mRNA alternative splicing is temporally and spatially regulated during chondrogenesis in vivo and in vitro. Dev. Dyn. 206:219-230.
17. Hedjran, F., J. Yeakley, G. Huh, R. Hynes, and M. Rosenfeld. 1997. Control of alternative pre-mRNA splicing by distributed pentameric repeats. Proc. Natl. Acad. Sci. USA 94:12343-12347.
18. Hertel, K., K. Lynch, and T. Maniatis. 1997. Common themes in the function of transcription and splicing enhancers. Curr. Opin. Cell Biol. 9:350-357.
19. Huh, G., and R. Hynes. 1993. Elements regulating an alternatively spliced exon of the rat fibronectin gene. Mol. Cell. Biol. 13:5301-5314.
20. Huh, G., and R. Hynes. 1994. Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element. Genes Dev. 8:1561-1574.
21. Jumaa, H., J. Guenet, and P. Nielsen. 1997. Regulated expression and RNA processing of transcripts from the Srp20 splicing factor gene during the cell cycle. Mol. Cell. Biol. 17:3116-3124.
22. Kawamoto, S. 1996. Neuron-specific alternative splicing of nonmuscle myosin II heavy chain-B pre-mRNA requires a cis-acting intron sequence. J. Biol. Chem. 271:17613-17616.
23. Kornblihtt, A., C. Pesce, C. Alonso, P. Cramer, A. Srebrow, S. Werbajh, and A. Muro. 1996. The fibronectin gene as a model for splicing and transcription studies. FASEB J. 10:248-257.
24. Krainer, A., G. Conway, and D. Kozak. 1990. Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells. Genes Dev. 4:1158-1171.
25. Lavigueur, A., H. LaBranche, A. Kornblihtt, and B. Chabot. 1993. A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding. Genes Dev. 7:2405-2417.
26. Lim, L., and P. Sharp. Unpublished data.
27. Manley, J., and R. Tacke. 1996. SR proteins and splicing control. Genes Dev. 10:1569-1579.
28. McCullough, A., and S. Berget. 1997. G triplets located throughout a class of small vertebrate introns enforce intron borders and regulate splice site selection. Mol. Cell. Biol. 17:4562-4571.
29. Min, H., C. Turck, J. Nikolic, and D. Black. 1997. A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev. 11:1023-1036.
30. Modafferi, E., and D. Black. 1997. A complex intronic splicing enhancer from the c-src pre-mRNA activates inclusion of a heterologous exon. Mol. Cell. Biol. 17:6537-6545.
31. Norton, P. 1994. Polypyrimidine tract sequences direct selection of alternative branch sites and influence protein binding. Nucleic Acids Res. 22:3854-3860.
32. Norton, P., and R. Hynes. 1990. In vitro splicing of fibronectin pre-mRNAs. Nucleic Acids Res. 18:4089-4097.
33. Peters, J., G. Chen, and R. Hynes. 1996. Fibronectin isoform distribution in the mouse. II. Differential distribution of the alternatively spliced EIIIB, EIIIA, and V segments in the adult mouse. Cell Adhes. Commun. 4:127-148.
34. Peters, J., and R. Hynes. 1996. Fibronectin isoform distribution in the mouse. I. The alternatively spliced EIIIB, EIIIA. and V segments show widespread codistribution in the developing mouse embryo. Cell Adhes. Commun. 4:103-125.
35. Screaton, G., J. Caceres, A. Mayeda, M. Bell, M. Plebanski, D. Jackson, J. Bell, and A. Krainer. 1995. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. EMBO J. 14:4336-4349.
36. Tacke, R., Y. Chen, and J. Manley. 1997. Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: creation of an SRp40-specific splicing enhancer. Proc. Natl. Acad. Sci. USA 94:1148-1153.
37. Takagaki, Y., R. Seipelt, M. Peterson, and J. Manley. 1996. The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation. Cell 87:941-952.
38. Wang, J., Y. Takagaki, and J. Manley. 1996. Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability. Genes Dev. 10:2588-2599.