Crystal structure and biochemical analysis of the MutS·ADP·beryllium fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair

Journal of Biological Chemistry

Volumn 278, Issue 18, 2003, Pages 16088-16094

  Alani, Eric ^a,b,c   Lee, Jae Young ^b   Schofield, Mark J ^b   Kijas, Amanda W ^a   Hsieh, Peggy ^b   Yang, Wei ^b,c  

^a Department of Obstetrics Gynecology   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c 459 Biotechnology Bldg ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL BONDS; COMPLEXATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DNA; HYDROLYSIS; REACTION KINETICS;

MISMATCH RECOGNITION;

PROTEINS;

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; FUNGAL PROTEIN; PROTEIN; PROTEIN MLH1 PMS1; PROTEIN MSH2 MSH6; PROTEIN MUTS; PROTEIN MUTS ADENOSINE DIPHOSPHATE FLUORIDE COMPLEX; UNCLASSIFIED DRUG; ADENOSINE DIPHOSPHATE; BACTERIAL PROTEIN; BERYLLIUM; BERYLLIUM FLUORIDE; CARRIER PROTEIN; DNA BINDING PROTEIN; ESCHERICHIA COLI PROTEIN; FLUORIDE; MLH1 PROTEIN, FUNGAL; MSH2 PROTEIN, FUNGAL; MSH2 PROTEIN, S CEREVISIAE; MSH6 PROTEIN, S CEREVISIAE; MUTS PROTEIN, E COLI; PROTEIN MSH2; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DNA REPAIR; ENZYME INHIBITION; HYDROLYSIS; HYPOTHESIS; MISMATCH REPAIR; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; THERMUS AQUATICUS; X RAY CRYSTALLOGRAPHY; BASE MISPAIRING; CHEMISTRY; CRYSTALLOGRAPHY; DRUG ANTAGONISM; METABOLISM;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; THERMUS; THERMUS AQUATICUS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEINS; BASE PAIR MISMATCH; BERYLLIUM; CARRIER PROTEINS; CRYSTALLOGRAPHY; DNA REPAIR; DNA-BINDING PROTEINS; ESCHERICHIA COLI PROTEINS; FLUORIDES; FUNGAL PROTEINS; MUTS DNA MISMATCH-BINDING PROTEIN; MUTS HOMOLOG 2 PROTEIN; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0038797998     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M213193200     Document Type: Article

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