-
2
-
-
0036304331
-
The mutator phenotype/clonal selection hypothesis can provide a basis for the complex and variable morphological and behavioural features of solid tumour malignancies
-
Bignold L. P. (2002) The mutator phenotype/clonal selection hypothesis can provide a basis for the complex and variable morphological and behavioural features of solid tumour malignancies. Cell Mol. Life Sci. 59: 950-958
-
(2002)
Cell Mol. Life Sci.
, vol.59
, pp. 950-958
-
-
Bignold, L.P.1
-
3
-
-
85039664040
-
The mutator phenotype theory of carcinogenesis and the complex histopathology of tumours: Support for the theory from the independent occurrence of nuclear abnormality, loss of specialisation and invasiveness among occasional neoplastic lesions
-
in press
-
Bignold L. P. The mutator phenotype theory of carcinogenesis and the complex histopathology of tumours: support for the theory from the independent occurrence of nuclear abnormality, loss of specialisation and invasiveness among occasional neoplastic lesions. Cell Mol. Life Sci., in press
-
Cell Mol. Life Sci.
-
-
Bignold, L.P.1
-
4
-
-
0004789413
-
Cell and molecular mechansims in chemical carcinogenesis
-
Peckham M., Pinedo H. and Veronesi U. (eds), Oxford University Press, Oxford
-
Cooper D. P., O'Connor P. J., Povey A. C. and Rafferty J. A. (1995) Cell and molecular mechansims in chemical carcinogenesis. In: Oxford Textbook of Oncology, pp. 135-147, Peckham M., Pinedo H. and Veronesi U. (eds), Oxford University Press, Oxford
-
(1995)
Oxford Textbook of Oncology
, pp. 135-147
-
-
Cooper, D.P.1
O'Connor, P.J.2
Povey, A.C.3
Rafferty, J.A.4
-
5
-
-
0002051192
-
Etiology of cancer. Chemical factors
-
DeVita V. T. Jr, Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
Yuspa S. H. and Shields P. G. (1997) Etiology of cancer. Chemical factors. In: Cancer, Principles and Practice of Oncology, 5th edn, pp. 185-202, DeVita V. T. Jr, Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
(1997)
Cancer, Principles and Practice of Oncology, 5th Edn.
, pp. 185-202
-
-
Yuspa, S.H.1
Shields, P.G.2
-
6
-
-
0033367088
-
The role of genomic instability in human carcinogenesis
-
Coleman W. B. and Tsongalis G. J. (1999) The role of genomic instability in human carcinogenesis. Anticancer Res. 19: 4645-4664
-
(1999)
Anticancer Res.
, vol.19
, pp. 4645-4664
-
-
Coleman, W.B.1
Tsongalis, G.J.2
-
7
-
-
0033035955
-
Genomic changes defining the genesis, progression and malignancy potential in solid human tumors: A phenotype/genotype correlation
-
Ried T., Heselmeyer-Haddad K., Blegen H., Schrock E. and Auer G. (1999) Genomic changes defining the genesis, progression and malignancy potential in solid human tumors: a phenotype/genotype correlation. Genes Chromosomes Cancer 25:195-204
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 195-204
-
-
Ried, T.1
Heselmeyer-Haddad, K.2
Blegen, H.3
Schrock, E.4
Auer, G.5
-
8
-
-
0036317839
-
Loss of heterozygosity or allele imbalance in histologically normal breast epithelium is distinct from loss of heterozygosity or allele imbalance in co-existing carcinomas
-
Larson P. S., de las Morenas A., Bennett S. R., Cupples L. A. and Rosenberg C. L. (2002) Loss of heterozygosity or allele imbalance in histologically normal breast epithelium is distinct from loss of heterozygosity or allele imbalance in co-existing carcinomas. Am. J. Pathol. 161: 283-290
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 283-290
-
-
Larson, P.S.1
De Las Morenas, A.2
Bennett, S.R.3
Cupples, L.A.4
Rosenberg, C.L.5
-
9
-
-
0035687513
-
Genetic instability in epithelial tissues at risk of cancer
-
Hittelman W. N. (2001) Genetic instability in epithelial tissues at risk of cancer. Ann. N. Y. Acad. Sci. 952: 1-12
-
(2001)
Ann. N. Y. Acad. Sci.
, vol.952
, pp. 1-12
-
-
Hittelman, W.N.1
-
10
-
-
0008006662
-
-
Saunders, Philadelphia
-
rd edn, Saunders, Philadelphia
-
(1928)
rd Edn.
-
-
Ewing, J.1
-
13
-
-
0034758874
-
Current molecular aspects of the carcinogenesis of the uterine endometrium
-
Inoue M. (2001) Current molecular aspects of the carcinogenesis of the uterine endometrium. Int. J. Gynecol. Cancer 11: 339-348
-
(2001)
Int. J. Gynecol. Cancer
, vol.11
, pp. 339-348
-
-
Inoue, M.1
-
14
-
-
0021868850
-
Regeneration and the mechanism of epidermal tumor promotion
-
Argyris T. S. (1985) Regeneration and the mechanism of epidermal tumor promotion. Crit. Rev. Toxicol. 14: 211-258
-
(1985)
Crit. Rev. Toxicol.
, vol.14
, pp. 211-258
-
-
Argyris, T.S.1
-
15
-
-
0015489740
-
Molecular repair, wound healing and carcinogenesis: Tumor production a possible overhealing?
-
Haddow A. (1972) Molecular repair, wound healing and carcinogenesis: tumor production a possible overhealing? Adv. Cancer Res. 6: 181-234
-
(1972)
Adv. Cancer Res.
, vol.6
, pp. 181-234
-
-
Haddow, A.1
-
16
-
-
0017153121
-
Nonimmunological host defenses: A review
-
Apffel C. A. (1976) Nonimmunological host defenses: a review. Cancer Res. 36: 1527-1537
-
(1976)
Cancer Res.
, vol.36
, pp. 1527-1537
-
-
Apffel, C.A.1
-
17
-
-
0017379403
-
Relationship between differentiation and carcinogenesis
-
Pierce G. B. (1977) Relationship between differentiation and carcinogenesis. J Toxicol. Environ. Health 2: 1335-1342
-
(1977)
J. Toxicol. Environ. Health
, vol.2
, pp. 1335-1342
-
-
Pierce, G.B.1
-
18
-
-
0014377762
-
The cancer cell as a stem cell unable to differentiate
-
Fiala S. (1968) The cancer cell as a stem cell unable to differentiate. Neoplasma 15: 607-622
-
(1968)
Neoplasma
, vol.15
, pp. 607-622
-
-
Fiala, S.1
-
19
-
-
0016605336
-
The role of DNA repair and somatic mutation in carcinogenesis
-
Trosko J. E. and Chu E. H. (1975) The role of DNA repair and somatic mutation in carcinogenesis. Adv. Cancer Res. 21: 391-425
-
(1975)
Adv. Cancer Res.
, vol.21
, pp. 391-425
-
-
Trosko, J.E.1
Chu, E.H.2
-
20
-
-
0019548446
-
An epigenetic model for the origin of cancer
-
Braun A. C. (1981) An epigenetic model for the origin of cancer. Q. Rev. Biol. 56: 33-60
-
(1981)
Q. Rev. Biol.
, vol.56
, pp. 33-60
-
-
Braun, A.C.1
-
21
-
-
0032862236
-
Differentiation: A central topic in developmental and cell biology
-
Muller W. A. (1999) Differentiation: a central topic in developmental and cell biology. Naturwissenschaften 86: 457-467
-
(1999)
Naturwissenschaften
, vol.86
, pp. 457-467
-
-
Muller, W.A.1
-
22
-
-
0002477990
-
Epithelial proliferative subpopulations
-
Cambridge University Press, Cambridge
-
Potten C. S. (1978) Epithelial proliferative subpopulations. In: Stem Cells and Tissue Homeostasis, pp. 315-334, Cambridge University Press, Cambridge
-
(1978)
Stem Cells and Tissue Homeostasis
, pp. 315-334
-
-
Potten, C.S.1
-
24
-
-
0346434985
-
-
Garland Science, New York
-
th edn, pp. 235-298 and 1313-1362, Garland Science, New York
-
(2002)
th Edn.
, pp. 235-298
-
-
Alberts, B.1
Johnson, A.2
Lewis, J.3
Raff, M.4
Roberts, K.5
Walter, P.6
-
25
-
-
0017261616
-
Carcinogenic mechanisms: A critical review and a suggestion that oncogenesis may be adaptive ontogenesis
-
Nery R. (1976) Carcinogenic mechanisms: a critical review and a suggestion that oncogenesis may be adaptive ontogenesis. Chem. Biol. Interact. 12: 145-69
-
(1976)
Chem. Biol. Interact.
, vol.12
, pp. 145-169
-
-
Nery, R.1
-
26
-
-
0027892512
-
Cellular origin of cancer: Dedifferentiation or stem cell maturation arrest?
-
Sell S. (1993) Cellular origin of cancer: dedifferentiation or stem cell maturation arrest? Environ. Health Perspect. 101 Suppl. 5: 15-26
-
(1993)
Environ. Health Perspect.
, vol.101
, Issue.SUPPL. 5
, pp. 15-26
-
-
Sell, S.1
-
28
-
-
0016195699
-
Regulation of membrane changes, differentiation and malignancy in carcinogenesis
-
Sachs L. (1974) Regulation of membrane changes, differentiation and malignancy in carcinogenesis. Harvey Lect. 68: 1-35
-
(1974)
Harvey Lect.
, vol.68
, pp. 1-35
-
-
Sachs, L.1
-
29
-
-
0019493823
-
Alterations in surface ultrastructure and anionic sites of rat dimethylhydrazine-induced intestinal tumors
-
Jacobs I. R. (1981) Alterations in surface ultrastructure and anionic sites of rat dimethylhydrazine-induced intestinal tumors. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 37: 207-216
-
(1981)
Virchows Arch. B Cell Pathol. Incl. Mol. Pathol.
, vol.37
, pp. 207-216
-
-
Jacobs, I.R.1
-
30
-
-
0034080924
-
Connexin gene mutations in human genetic diseases
-
Krutovskikh V. andYamasaki H. (2000) Connexin gene mutations in human genetic diseases. Mutat. Res. 462: 197-207
-
(2000)
Mutat. Res.
, vol.462
, pp. 197-207
-
-
Krutovskikh, V.1
Yamasaki, H.2
-
31
-
-
0035451330
-
Mechanism of up-regulated gap junctional intercellular communication during chemoprevention and chemotherapy of cancer
-
Trosko J. E. and Chang C. C. (2001) Mechanism of up-regulated gap junctional intercellular communication during chemoprevention and chemotherapy of cancer. Mutat. Res. 480-481: 219-229.
-
(2001)
Mutat. Res.
, vol.480-481
, pp. 219-229
-
-
Trosko, J.E.1
Chang, C.C.2
-
32
-
-
0035226207
-
'The metabolism of tumours': 70 Years later
-
Semenza G. L., Artemov D., Bedi A., Bhujwalla Z., Chiles K., Feldser D. et al (2001) 'The metabolism of tumours': 70 years later. Novartis Found. Symp. 240: 251-260
-
(2001)
Novartis Found. Symp.
, vol.240
, pp. 251-260
-
-
Semenza, G.L.1
Artemov, D.2
Bedi, A.3
Bhujwalla, Z.4
Chiles, K.5
Feldser, D.6
-
33
-
-
0027361208
-
Models of neoplasia and their diagnostic implications: A historical perspective
-
Goldberg D. M. and Diamandis E. P. (1993) Models of neoplasia and their diagnostic implications: a historical perspective. Clin. Chem. 39: 2360-2374
-
(1993)
Clin. Chem.
, vol.39
, pp. 2360-2374
-
-
Goldberg, D.M.1
Diamandis, E.P.2
-
34
-
-
0029077985
-
The significance of the cholesterol biosynthetic pathway in cell growth and carcinogenesis
-
Rao K. N. (1995) The significance of the cholesterol biosynthetic pathway in cell growth and carcinogenesis (review). Anticancer Res. 15: 309-314
-
(1995)
Anticancer Res.
, vol.15
, pp. 309-314
-
-
Rao, K.N.1
-
35
-
-
0034011261
-
Oxyradicals and DNA damage
-
Marnett L. J. (2000) Oxyradicals and DNA damage. Carcinogenesis 21: 361-370
-
(2000)
Carcinogenesis
, vol.21
, pp. 361-370
-
-
Marnett, L.J.1
-
36
-
-
0027938689
-
Oxy-radicals and cancer
-
Cerutti P. A. (1994) Oxy-radicals and cancer. Lancet 344: 862-863
-
(1994)
Lancet
, vol.344
, pp. 862-863
-
-
Cerutti, P.A.1
-
37
-
-
0034676492
-
A causal relationship between unscheduled eicosanoid signaling and tumor development: Cancer chemoprevention by inhibitors of arachidonic acid metabolism
-
Marks F., Muller-Decker K. and Furstenberger G. (2000) A causal relationship between unscheduled eicosanoid signaling and tumor development: cancer chemoprevention by inhibitors of arachidonic acid metabolism. Toxicology 153: 11-26
-
(2000)
Toxicology
, vol.153
, pp. 11-26
-
-
Marks, F.1
Muller-Decker, K.2
Furstenberger, G.3
-
38
-
-
0035296203
-
Role of nitric oxide in carcinogenesis and tumour progression
-
Lala P. K. and Chakraborty C. (2001) Role of nitric oxide in carcinogenesis and tumour progression. Lancet Oncol. 2: 149-156
-
(2001)
Lancet Oncol.
, vol.2
, pp. 149-156
-
-
Lala, P.K.1
Chakraborty, C.2
-
39
-
-
0026072467
-
Nonmutagenic mechanisms in carcinogenesis: Role of protein kinase C in signal transduction and growth control
-
Weinstein I. B. (1991) Nonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth control. Environ. Health Perspect. 93: 175-179
-
(1991)
Environ. Health Perspect.
, vol.93
, pp. 175-179
-
-
Weinstein, I.B.1
-
40
-
-
0036490157
-
Id proteins - Tumor markers or oncogenes?
-
Hasskarl J. and Munger K. (2002) Id proteins - tumor markers or oncogenes? Cancer Biol. Ther. 1: 91-96
-
(2002)
Cancer Biol. Ther.
, vol.1
, pp. 91-96
-
-
Hasskarl, J.1
Munger, K.2
-
42
-
-
54249116230
-
Genetic regulatory mechanisms in the synthesis of proteins
-
Jacob F. and Monod J (1961) Genetic regulatory mechanisms in the synthesis of proteins. J Mol. Biol. 3: 318-356
-
(1961)
J. Mol. Biol.
, vol.3
, pp. 318-356
-
-
Jacob, F.1
Monod, J.2
-
43
-
-
0014720786
-
Epigenetic processes and their relevance to the study of neoplasia
-
Sherbert G. V. (1970) Epigenetic processes and their relevance to the study of neoplasia. Adv. Cancer Res. 13: 97-167
-
(1970)
Adv. Cancer Res.
, vol.13
, pp. 97-167
-
-
Sherbert, G.V.1
-
45
-
-
0033382990
-
Cell damage, aging and transformation: A multilevel analysis of carcinogenesis
-
Rubin H. (1999) Cell damage, aging and transformation: a multilevel analysis of carcinogenesis. Anticancer Res. 19: 4877-4886
-
(1999)
Anticancer Res.
, vol.19
, pp. 4877-4886
-
-
Rubin, H.1
-
46
-
-
0002861227
-
Principles of molecular cell biology of cancer: Growth factors
-
DeVita V. T. Jr, Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
Mendelson J. and Lippman M. E. (1993). Principles of molecular cell biology of cancer: growth factors. In: Cancer, Principles and Practice of Oncology, 4th edn, pp. 114-133, DeVita V. T. Jr, Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
(1993)
Cancer, Principles and Practice of Oncology, 4th Edn.
, pp. 114-133
-
-
Mendelson, J.1
Lippman, M.E.2
-
47
-
-
0010523031
-
Polypeptide and neuropeptide grqoth factos: Signalling pathways and role in cancer
-
Peckham M., Pinedo H. and U Veronesi U. (eds), Oxford University Press, Oxford
-
Rozengurt E. (1995) Polypeptide and neuropeptide grqoth factos: signalling pathways and role in cancer. In: Peckham M., Pinedo H. and U Veronesi U. (eds), Oxford Textbook of Oncology, pp. 12-20, Oxford University Press, Oxford
-
(1995)
Oxford Textbook of Oncology
, pp. 12-20
-
-
Rozengurt, E.1
-
48
-
-
0021958679
-
Autocrine growth factors and cancer
-
Sporn M. B. and Roberts A. B. (1985) Autocrine growth factors and cancer. Nature 313: 745-747
-
(1985)
Nature
, vol.313
, pp. 745-747
-
-
Sporn, M.B.1
Roberts, A.B.2
-
49
-
-
0003422388
-
-
W. H. Freeman, New York
-
Lodish H., Berk A., Zipursky S. L., Matsudaira P., Baltimore D. and Darnell J. (eds) (2000), Molecular Cell Biology, pp. 1066-1067, W. H. Freeman, New York
-
(2000)
Molecular Cell Biology
, pp. 1066-1067
-
-
Lodish, H.1
Berk, A.2
Zipursky, S.L.3
Matsudaira, P.4
Baltimore, D.5
Darnell, J.6
-
50
-
-
0012018756
-
Oncogenes and cell proliferation: An overview
-
D. M. Glover, and B. D. Hames (eds), IRL Press, Oxford
-
Marshall C. J. (1989) Oncogenes and cell proliferation: an overview. In: Oncogenes, pp. 1-21, D. M. Glover, and B. D. Hames (eds), IRL Press, Oxford
-
(1989)
Oncogenes
, pp. 1-21
-
-
Marshall, C.J.1
-
52
-
-
0004191854
-
-
Oxford University Press, Oxford
-
rd edn, p. 222, Oxford University Press, Oxford
-
(1991)
rd Edn.
, pp. 222
-
-
Weatherall, D.J.1
-
53
-
-
0038227159
-
Principles of cancer management: Cancer genetics
-
DeVita, V. T., Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
Bale A. E. and Li F. P. (1997) Principles of cancer management: cancer genetics. In: Cancer: Principles and Practice of Oncology, 5th edn, pp. 285-293, DeVita, V. T., Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
(1997)
Cancer: Principles and Practice of Oncology, 5th Edn.
, pp. 285-293
-
-
Bale, A.E.1
Li, F.P.2
-
54
-
-
0026059515
-
Tumor suppressor genes
-
Marshall C. J. (1991) Tumor suppressor genes. Cell 64: 313-326
-
(1991)
Cell
, vol.64
, pp. 313-326
-
-
Marshall, C.J.1
-
55
-
-
0025976103
-
Recessive oncogenes, antioncogenes and tumour suppression
-
Mitchell C. D. (1991) Recessive oncogenes, antioncogenes and tumour suppression. Br. Med. Bull. 47: 136-56
-
(1991)
Br. Med. Bull.
, vol.47
, pp. 136-156
-
-
Mitchell, C.D.1
-
56
-
-
0021332973
-
Retinoblastoma: Clues to human oncogenesis
-
Murphree A. L. and Benedict W. F. (1984) Retinoblastoma: clues to human oncogenesis. Science 223: 1028-1033
-
(1984)
Science
, vol.223
, pp. 1028-1033
-
-
Murphree, A.L.1
Benedict, W.F.2
-
57
-
-
0344766067
-
The emerging p53 gene family
-
Kaelin W. G. (1999) The emerging p53 gene family. J. Natl. Cancer Inst. 91: 594-598
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 594-598
-
-
Kaelin, W.G.1
-
58
-
-
0032988122
-
Introduction: p53 - The first twenty years
-
Oren M. and Rotter V. (1999) Introduction: p53 - the first twenty years. Cell Mol. Life Sci. 55: 9-11
-
(1999)
Cell Mol. Life Sci.
, vol.55
, pp. 9-11
-
-
Oren, M.1
Rotter, V.2
-
59
-
-
0027401607
-
The multistep nature of cancer
-
Vogelstein B. and Kinzler K. W. (1993) The multistep nature of cancer. Trends Genet. 9: 138-141
-
(1993)
Trends Genet.
, vol.9
, pp. 138-141
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
60
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler K. W. and Vogelstein B. (1996) Lessons from hereditary colorectal cancer. Cell 87: 159-170
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
61
-
-
0028559017
-
Hypomethylation of DNA: An epigenetic mechanism involved in tumor promotion
-
Counts J. L. and Goodman J. I. (1994) Hypomethylation of DNA: an epigenetic mechanism involved in tumor promotion. Mol. Carcinog. 11: 185-188
-
(1994)
Mol. Carcinog.
, vol.11
, pp. 185-188
-
-
Counts, J.L.1
Goodman, J.I.2
-
62
-
-
0031467130
-
X-chromosome inactivation in mammals
-
Heard E., Clerc P. and Avner P. (1997) X-chromosome inactivation in mammals. Annu. Rev. Genet. 31: 571-610
-
(1997)
Annu. Rev. Genet.
, vol.31
, pp. 571-610
-
-
Heard, E.1
Clerc, P.2
Avner, P.3
-
63
-
-
0034003798
-
Epigenetic gene silencing in cancer
-
Tycko B. (2000) Epigenetic gene silencing in cancer. J. Clin. Invest. 105: 401-407
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 401-407
-
-
Tycko, B.1
-
64
-
-
0032960181
-
Cancer epigenetics comes of age
-
Jones P. A. and Laird P. W. (1999) Cancer epigenetics comes of age. Nat. Genet. 21: 163-167
-
(1999)
Nat. Genet.
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
65
-
-
0034176798
-
DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
-
Baylin S. B. and Herman J. G. (2000) DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet. 16: 168-174
-
(2000)
Trends Genet.
, vol.16
, pp. 168-174
-
-
Baylin, S.B.1
Herman, J.G.2
-
66
-
-
0037068353
-
DNA methylation in cancer: Too much, but also too little
-
Ehrlich M. (2002) DNA methylation in cancer: too much, but also too little. Oncogene 21: 5400-1354
-
(2002)
Oncogene
, vol.21
, pp. 5400-1354
-
-
Ehrlich, M.1
-
67
-
-
0025805631
-
Transcription and cancer
-
Cox P. M. and Goding C. R. (1991) Transcription and cancer. Br. J. Cancer 63: 651-662
-
(1991)
Br. J. Cancer
, vol.63
, pp. 651-662
-
-
Cox, P.M.1
Goding, C.R.2
-
70
-
-
0027880281
-
Cell cycle controls: Potential targets for chemical carcinogens?
-
Afshari C. A. and Barrett J. C. (1993) Cell cycle controls: potential targets for chemical carcinogens? Environ. Health Perspect. 101 Suppl. 5: 9-14
-
(1993)
Environ. Health Perspect.
, vol.101
, Issue.SUPPL. 5
, pp. 9-14
-
-
Afshari, C.A.1
Barrett, J.C.2
-
71
-
-
0035063789
-
Molecular profiling of breast cancer: Portraits but not physiognomy
-
Brenton J. D., Aparicio S. A. and Caldas C. (2001) Molecular profiling of breast cancer: portraits but not physiognomy. Breast Cancer Res. 3: 77-80
-
(2001)
Breast Cancer Res.
, vol.3
, pp. 77-80
-
-
Brenton, J.D.1
Aparicio, S.A.2
Caldas, C.3
-
73
-
-
0038227158
-
The study of tumours in animals
-
rd edn, Lloyd-Luke, London
-
rd edn, pp. 622-658, Lloyd-Luke, London
-
(1964)
General Pathology
, pp. 622-658
-
-
Berenblum, I.1
-
74
-
-
0019829342
-
Mechanisms of chemical carcinogenesis
-
Miller E. C. and Miller J. A. (1981) Mechanisms of chemical carcinogenesis. Cancer 47 (5 Suppl.): 1055-1064
-
(1981)
Cancer
, vol.47
, Issue.5 SUPPL.
, pp. 1055-1064
-
-
Miller, E.C.1
Miller, J.A.2
-
75
-
-
0022841074
-
Critical genetic determinants and molecular events in multistage skin carcinogenesis
-
Slaga T. J., O'Connell J., Rotstein J., Patskan G., Morris R., Aldaz C. M. et al. (1986) Critical genetic determinants and molecular events in multistage skin carcinogenesis. Symp. Fundam. Cancer Res. 39: 31-44.
-
(1986)
Symp. Fundam. Cancer Res.
, vol.39
, pp. 31-44
-
-
Slaga, T.J.1
O'Connell, J.2
Rotstein, J.3
Patskan, G.4
Morris, R.5
Aldaz, C.M.6
-
76
-
-
0027274815
-
The molecular biology of carcinogenesis
-
Pitot H. C. (1993) The molecular biology of carcinogenesis. Cancer 72 (3 Suppl.): 962-70
-
(1993)
Cancer
, vol.72
, Issue.3 SUPPL.
, pp. 962-970
-
-
Pitot, H.C.1
-
77
-
-
0033782874
-
The origin of oncogenic mutations: Where is the primary damage?
-
Steen H. B. (2000) The origin of oncogenic mutations: where is the primary damage? Carcinogenesis 21: 1773-1776
-
(2000)
Carcinogenesis
, vol.21
, pp. 1773-1776
-
-
Steen, H.B.1
-
79
-
-
0022160578
-
Multistage models of carcinogenesis
-
Armitage P. (1985) Multistage models of carcinogenesis. Environ. Health Perspect. 63: 195-201
-
(1985)
Environ. Health Perspect.
, vol.63
, pp. 195-201
-
-
Armitage, P.1
-
80
-
-
0025312380
-
The Armitage-Doll multistage model of carcinogenesis
-
Day N. E. (1990) The Armitage-Doll multistage model of carcinogenesis. Stat. Med. 9: 677-679
-
(1990)
Stat. Med.
, vol.9
, pp. 677-679
-
-
Day, N.E.1
-
81
-
-
0027130929
-
Multistage carcinogenesis - Genetic and epigenetic mechanisms in relation to cancer prevention
-
11993
-
Pitot H. C. (11993) Multistage carcinogenesis - genetic and epigenetic mechanisms in relation to cancer prevention. Cancer Detect. Prev. 17: 567-573
-
Cancer Detect. Prev.
, vol.17
, pp. 567-573
-
-
Pitot, H.C.1
-
82
-
-
0025486010
-
Modulation of intercellular communication during radiation and chemical carcinogenesis
-
Trosko J. E., Chang C. C. and Madhukar B. V. (1990) Modulation of intercellular communication during radiation and chemical carcinogenesis. Radiat. Res. 123: 241-251
-
(1990)
Radiat. Res.
, vol.123
, pp. 241-251
-
-
Trosko, J.E.1
Chang, C.C.2
Madhukar, B.V.3
-
84
-
-
0000078117
-
Molecular biology of cancer: Invasion and metastasis
-
DeVita, V. T., Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
Fidler I. J. (1997). Molecular biology of cancer: invasion and metastasis. In: Cancer: Principles and Practice of Oncology, 5th edn, pp. 135-152, DeVita, V. T., Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
(1997)
Cancer: Principles and Practice of Oncology, 5th Edn.
, pp. 135-152
-
-
Fidler, I.J.1
-
85
-
-
0029919109
-
Hereditary cancer: Two hits revisited
-
Knudson A. G. (1996) Hereditary cancer: two hits revisited. J. Cancer Res. Clin. Oncol. 122: 135-140
-
(1996)
J. Cancer Res. Clin. Oncol.
, vol.122
, pp. 135-140
-
-
Knudson, A.G.1
-
86
-
-
0034511179
-
Chasing the cancer demon
-
Knudson A. G. (2000) Chasing the cancer demon. Annu. Rev. Genet. 34: 1-19
-
(2000)
Annu. Rev. Genet.
, vol.34
, pp. 1-19
-
-
Knudson, A.G.1
-
87
-
-
0035522894
-
Two genetic hits (more or less) to cancer
-
Knudson A. G. (2001) Two genetic hits (more or less) to cancer. Nat. Rev. Cancer. 1: 157-162
-
(2001)
Nat. Rev. Cancer.
, vol.1
, pp. 157-162
-
-
Knudson, A.G.1
-
89
-
-
0028691022
-
From fluorescence spectra to mutational spectra, a historical overview and DNA-reactive compounds
-
Lawley P. D. (1994) From fluorescence spectra to mutational spectra, a historical overview and DNA-reactive compounds. IARC Scientific Publication No. 125: 3-22.
-
(1994)
IARC Scientific Publication
, vol.125
, pp. 3-22
-
-
Lawley, P.D.1
-
90
-
-
0025250171
-
Protein adducts in the molecular dosimetry of chemical carcinogens
-
Skipper P. L. and Tannenbaum S. R. (1990) Protein adducts in the molecular dosimetry of chemical carcinogens. Carcinogenesis 11: 507-518
-
(1990)
Carcinogenesis
, vol.11
, pp. 507-518
-
-
Skipper, P.L.1
Tannenbaum, S.R.2
-
91
-
-
0034027867
-
Studies on biomarkers in cancer etiology and prevention: A summary and challenge of 20 years of inter-disciplinary research
-
Bartsch H. (2000) Studies on biomarkers in cancer etiology and prevention: a summary and challenge of 20 years of inter-disciplinary research. Mutat. Res. 462: 255-279
-
(2000)
Mutat. Res.
, vol.462
, pp. 255-279
-
-
Bartsch, H.1
-
92
-
-
0034092008
-
Carcinogen macromolecular adducts and their measurement
-
Poirier M. C., Santella R. M. and Weston A. (2000) Carcinogen macromolecular adducts and their measurement. Carcinogenesis 21: 353-359
-
(2000)
Carcinogenesis
, vol.21
, pp. 353-359
-
-
Poirier, M.C.1
Santella, R.M.2
Weston, A.3
-
93
-
-
0037192321
-
Molecular epidemiology and cancer: Promising areas for future research in the post-genomic era
-
Wild C. P., Law G. R. and Roman E. (2002) Molecular epidemiology and cancer: promising areas for future research in the post-genomic era. Mutat. Res. 499: 3-512
-
(2002)
Mutat. Res.
, vol.499
, pp. 3-512
-
-
Wild, C.P.1
Law, G.R.2
Roman, E.3
-
94
-
-
0027881803
-
Absence of morphologic correlation between chemical toxicity and chemical carcinogenesis
-
Huff J. (1993) Absence of morphologic correlation between chemical toxicity and chemical carcinogenesis. Environ. Health Perspect. 101 Suppl. 5: 45-53
-
(1993)
Environ. Health Perspect.
, vol.101
, Issue.SUPPL. 5
, pp. 45-53
-
-
Huff, J.1
-
95
-
-
0029314191
-
DNA adducts in human carcinogenesis: Etiological relevance and structure-activity relationship
-
Bartsch H. (1996) DNA adducts in human carcinogenesis: etiological relevance and structure-activity relationship. Mutat. Res. 340: 67-79
-
(1996)
Mutat. Res.
, vol.340
, pp. 67-79
-
-
Bartsch, H.1
-
96
-
-
0032543359
-
The role of DNA adducts in chemical carcinogenesis
-
Garner R. C. (1998) The role of DNA adducts in chemical carcinogenesis. Mutat. Res. 402: 67-75
-
(1998)
Mutat. Res.
, vol.402
, pp. 67-75
-
-
Garner, R.C.1
-
97
-
-
0034125042
-
DNA adducts: Endogenous and induced
-
Povey A. C. (2000) DNA adducts: endogenous and induced. Toxicol. Pathol. 28: 405-414
-
(2000)
Toxicol. Pathol.
, vol.28
, pp. 405-414
-
-
Povey, A.C.1
-
98
-
-
0033804390
-
Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens
-
Seo K. Y., Jelinsky S. A. and Loechler E. L. (2000) Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens. Mutat. Res. 463: 215-246
-
(2000)
Mutat. Res.
, vol.463
, pp. 215-246
-
-
Seo, K.Y.1
Jelinsky, S.A.2
Loechler, E.L.3
-
99
-
-
0036382913
-
Toward understanding the mutagenicity of an environmental carcinogen: Structural insights into nucleotide incorporation preferences
-
Perlow RA, Broyde S. (2002) Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences. J. Mol. Biol. 322: 291-309
-
(2002)
J. Mol. Biol.
, vol.322
, pp. 291-309
-
-
Perlow, R.A.1
Broyde, S.2
-
100
-
-
0035366319
-
Evading the proofreading machinery of a replicative DNA polymerase: Induction of a mutation by an environmental carcinogen
-
Perlow R. A. and Broyde S. (2001) Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen. J. Mol. Biol. 309: 519-536
-
(2001)
J. Mol. Biol.
, vol.309
, pp. 519-536
-
-
Perlow, R.A.1
Broyde, S.2
-
101
-
-
0034471653
-
DNA adducts, mutations, and cancer 2000
-
Hemminki K., Koskinen M., Rajaniemi H. and Zhao C. (2000) DNA adducts, mutations, and cancer 2000. Regul. Toxicol. Pharmacol. 32: 264-275
-
(2000)
Regul. Toxicol. Pharmacol.
, vol.32
, pp. 264-275
-
-
Hemminki, K.1
Koskinen, M.2
Rajaniemi, H.3
Zhao, C.4
-
102
-
-
0031204599
-
Photocarcinogenesis: An overview
-
Black H. S., deGruijl F. R., Forbes P. D., Cleaver J. E., Ananthaswamy H. N., deFabo E. C. et al (1997) Photocarcinogenesis: an overview. J. Photochem. Photobiol. B 40: 29-47
-
(1997)
J. Photochem. Photobiol. B
, vol.40
, pp. 29-47
-
-
Black, H.S.1
DeGruijl, F.R.2
Forbes, P.D.3
Cleaver, J.E.4
Ananthaswamy, H.N.5
DeFabo, E.C.6
-
103
-
-
0030904893
-
DNA methylation, heterochromatin and epigenetic carcinogens
-
Klein C. B. and Costa M. (1997) DNA methylation, heterochromatin and epigenetic carcinogens. Mutat. Res. 386: 163-180
-
(1997)
Mutat. Res.
, vol.386
, pp. 163-180
-
-
Klein, C.B.1
Costa, M.2
-
104
-
-
0027463052
-
Comparison of target organs of carcinogenicity for mutagenic and non-mutagenic chemicals
-
Gold L. S., Slone T. H., Stern B. R. and Bernstein L. (1993) Comparison of target organs of carcinogenicity for mutagenic and non-mutagenic chemicals. Mutat. Res. 286: 75-100
-
(1993)
Mutat. Res.
, vol.286
, pp. 75-100
-
-
Gold, L.S.1
Slone, T.H.2
Stern, B.R.3
Bernstein, L.4
-
105
-
-
0026683780
-
Non-genotoxic factors in the carcinogenetic process: Problems of detection and hazard evaluation
-
Parodi S., Malacarne D. and Taningher M. (1992) Non-genotoxic factors in the carcinogenetic process: problems of detection and hazard evaluation. Toxicol. Lett. 64-65: 621-630
-
(1992)
Toxicol. Lett.
, vol.64-65
, pp. 621-630
-
-
Parodi, S.1
Malacarne, D.2
Taningher, M.3
-
106
-
-
0035061652
-
Commentary: Is the concept of 'tumour promotion' a useful paradigm?
-
Trosko J. E. (2001) Commentary: is the concept of 'tumour promotion' a useful paradigm? Mol. Carcinog. 30: 131-137
-
(2001)
Mol. Carcinog.
, vol.30
, pp. 131-137
-
-
Trosko, J.E.1
-
107
-
-
0032579187
-
Studies of initiation and promotion of carcinogenesis by N-nitroso compounds
-
Hasegawa R., Futakuchi M., Mizoguchi Y., Yamaguchi T., Shirai T., Ito N. et al (1998) Studies of initiation and promotion of carcinogenesis by N-nitroso compounds. Cancer Lett. 123: 185-191
-
(1998)
Cancer Lett.
, vol.123
, pp. 185-191
-
-
Hasegawa, R.1
Futakuchi, M.2
Mizoguchi, Y.3
Yamaguchi, T.4
Shirai, T.5
Ito, N.6
-
109
-
-
0033163236
-
Epigenetic events during the process of cell transformation induced by carcinogens
-
Nguyen-Ba G. and Vasseur P. (1999) Epigenetic events during the process of cell transformation induced by carcinogens (review). Oncol. Rep. 6: 925-932
-
(1999)
Oncol. Rep.
, vol.6
, pp. 925-932
-
-
Nguyen-Ba, G.1
Vasseur, P.2
-
110
-
-
0035978873
-
Mutagens that are not carcinogens: Faulty theory or faulty tests?
-
Zeiger E. (2001) Mutagens that are not carcinogens: faulty theory or faulty tests? Mutat. Res. 492: 29-38
-
(2001)
Mutat. Res.
, vol.492
, pp. 29-38
-
-
Zeiger, E.1
-
111
-
-
0029435518
-
Of mice and men: A critical reappraisal of the two-stage theory of carcinogenesis
-
Iversen O. H. (1995) Of mice and men: a critical reappraisal of the two-stage theory of carcinogenesis. Crit. Rev. Oncog. 6: 357-405
-
(1995)
Crit. Rev. Oncog.
, vol.6
, pp. 357-405
-
-
Iversen, O.H.1
-
112
-
-
0037611834
-
Genetic instability in Escherichia coli
-
Schwartz N. M. (1965) Genetic instability in Escherichia coli. J. Bacteriol. 89: 712-717.
-
(1965)
J. Bacteriol.
, vol.89
, pp. 712-717
-
-
Schwartz, N.M.1
-
113
-
-
0014151680
-
Altered base ratios in the DNA of an Escherichia coli mutator strain
-
Cox E. C. and Yanofsky C. (1967) Altered base ratios in the DNA of an Escherichia coli mutator strain. Proc. Natl Acad. Sci. USA 58: 1895-1902
-
(1967)
Proc. Natl. Acad. Sci. USA
, vol.58
, pp. 1895-1902
-
-
Cox, E.C.1
Yanofsky, C.2
-
115
-
-
0034500024
-
DNA mismatch repair and genetic instability
-
Harfe B. D. and Jinks-Robertson S. (2000) DNA mismatch repair and genetic instability. Annu. Rev. Genet. 34: 359-399
-
(2000)
Annu. Rev. Genet.
, vol.34
, pp. 359-399
-
-
Harfe, B.D.1
Jinks-Robertson, S.2
-
116
-
-
0002002741
-
Genetic stability and instability in turnouts
-
M. Sluyser (ed.), Ellis Horwood, New York
-
Volpe J. (1990) Genetic stability and instability in turnouts. In: Molecular Biology of Cancer Genes, pp. 9-23. M. Sluyser (ed.), Ellis Horwood, New York
-
(1990)
Molecular Biology of Cancer Genes
, pp. 9-23
-
-
Volpe, J.1
-
117
-
-
0015083627
-
Genetic implication of karyological instability of malignant somatic cells
-
Ono S. (1971) Genetic implication of karyological instability of malignant somatic cells. Physiol. Rev. 51: 496-526.
-
(1971)
Physiol. Rev.
, vol.51
, pp. 496-526
-
-
Ono, S.1
-
118
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell P. C. (1976) The clonal evolution of tumor cell populations. Science 194: 23-28
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
119
-
-
0016692602
-
Mutation selection and the natural history of cancer
-
Cairns J. (1975) Mutation selection and the natural history of cancer. Nature 255: 197-200
-
(1975)
Nature
, vol.255
, pp. 197-200
-
-
Cairns, J.1
-
120
-
-
0014421995
-
Defective repair replication of DNA in xeroderma pigmentosum
-
Cleaver J. E. (1968) Defective repair replication of DNA in xeroderma pigmentosum. Nature 218: 652-656
-
(1968)
Nature
, vol.218
, pp. 652-656
-
-
Cleaver, J.E.1
-
121
-
-
0033592960
-
The onset and extent of genomic instability in sporadic colorectal tumor progression
-
Stoler D. L., Chen N., Basik M., Kahlenberg M. S., Rodriguez-Bigas M. A., Petrelli N. J. et al. (1999) The onset and extent of genomic instability in sporadic colorectal tumor progression. Proc. Natl Acad. Sci. USA 96: 15121-15126
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 15121-15126
-
-
Stoler, D.L.1
Chen, N.2
Basik, M.3
Kahlenberg, M.S.4
Rodriguez-Bigas, M.A.5
Petrelli, N.J.6
-
122
-
-
0020286123
-
Is the establishment of a clone exhibiting defective DNA repair the initial stage of carcinogenesis?
-
Riley P. A. (1982) Is the establishment of a clone exhibiting defective DNA repair the initial stage of carcinogenesis? Med. Hypotheses 9: 163-168
-
(1982)
Med. Hypotheses
, vol.9
, pp. 163-168
-
-
Riley, P.A.1
-
123
-
-
0025615595
-
Is the initial event in carcinogenesis an enhancement of the mutation rate?
-
Riley P. A. (1990) Is the initial event in carcinogenesis an enhancement of the mutation rate? Free Radic. Res. Commun. 11: 59-63
-
(1990)
Free Radic. Res. Commun.
, vol.11
, pp. 59-63
-
-
Riley, P.A.1
-
124
-
-
0030442815
-
Many mutations in cancers
-
Loeb L. A. (1996) Many mutations in cancers. Cancer Surv. 28: 329-342
-
(1996)
Cancer Surv.
, vol.28
, pp. 329-342
-
-
Loeb, L.A.1
-
125
-
-
0034011427
-
Significance of multiple mutations in cancer
-
Loeb K. R. and Loeb L. A. (2000) Significance of multiple mutations in cancer. Carcinogenesis 21: 379-385
-
(2000)
Carcinogenesis
, vol.21
, pp. 379-385
-
-
Loeb, K.R.1
Loeb, L.A.2
-
126
-
-
0035870243
-
A mutator phenotype in cancer
-
Loeb L. A. (2001) A mutator phenotype in cancer. Cancer Res. 61: 230-239
-
(2001)
Cancer Res.
, vol.61
, pp. 230-239
-
-
Loeb, L.A.1
-
127
-
-
0033395272
-
Genomic instability: First step to carcinogenesis
-
Schmutte C. and Fishel R. (1999) Genomic instability: first step to carcinogenesis. Anticancer Res. 19: 4665-4696
-
(1999)
Anticancer Res.
, vol.19
, pp. 4665-4696
-
-
Schmutte, C.1
Fishel, R.2
-
129
-
-
0029095626
-
Interaction of bulky chemical carcinogens with DNA in chromatin
-
MacLeod M. C. (1995) Interaction of bulky chemical carcinogens with DNA in chromatin. Carcinogenesis 16: 2009-2014
-
(1995)
Carcinogenesis
, vol.16
, pp. 2009-2014
-
-
MacLeod, M.C.1
-
130
-
-
0028073444
-
Base-specific arrest of in vitro DNA replication by carcinogenic chromium: Relationship to DNA interstrand crosslinking
-
Bridgewater L. C., Manning F. C. and Patierno S. R. (1994) Base-specific arrest of in vitro DNA replication by carcinogenic chromium: relationship to DNA interstrand crosslinking. Carcinogenesis 15: 2421-2427
-
(1994)
Carcinogenesis
, vol.15
, pp. 2421-2427
-
-
Bridgewater, L.C.1
Manning, F.C.2
Patierno, S.R.3
-
133
-
-
0023219250
-
Persistent structural change in replicating hepatic DNA isolated from diethylnitrosamine-treated rats
-
Stewart B. W. and Hristoforidis C. (1987) Persistent structural change in replicating hepatic DNA isolated from diethylnitrosamine-treated rats. Cancer Lett. 35: 263-269
-
(1987)
Cancer Lett.
, vol.35
, pp. 263-269
-
-
Stewart, B.W.1
Hristoforidis, C.2
-
135
-
-
0002926374
-
Hormonal therapies
-
DeVita, V. T., Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
Ehrlichman C. and Loprinzi C. L. (1997) Hormonal therapies. In: Cancer: Principles and Practice of Oncology, 5th edn, pp. 395-405, DeVita, V. T., Hellman S. and Rosenberg S. A. (eds), Lippincott-Raven, Philadelphia
-
(1997)
Cancer: Principles and Practice of Oncology, 5th Edn.
, pp. 395-405
-
-
Ehrlichman, C.1
Loprinzi, C.L.2
-
136
-
-
84989405875
-
Synchronization of mammalian cells with respect to the mitotic cycle
-
Nais A.H. and Fox M. (1971) Synchronization of mammalian cells with respect to the mitotic cycle. Cell Tissue Kinet. 4: 375-398
-
(1971)
Cell Tissue Kinet.
, vol.4
, pp. 375-398
-
-
Nais, A.H.1
Fox, M.2
-
137
-
-
0032925857
-
Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast
-
Tran H. T., Degtyareva N. P., Gordenin D. A. and Resnick M. A. (1999) Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast. Genetics 152: 47-59
-
(1999)
Genetics
, vol.152
, pp. 47-59
-
-
Tran, H.T.1
Degtyareva, N.P.2
Gordenin, D.A.3
Resnick, M.A.4
|