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Volumn 159, Issue 10, 1997, Pages 4720-4728

Constitutive Activation of JAKs and STATs in BCR-Abl-Expressing Cell Lines and Peripheral Blood Cells Derived from Leukemic Patients

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; DNA BINDING PROTEIN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; MILK PROTEIN; PROTEIN TYROSINE KINASE; STAT1 PROTEIN; STAT1 PROTEIN, HUMAN; STAT1 PROTEIN, MOUSE; STAT5 PROTEIN; TRANSACTIVATOR PROTEIN;

EID: 0031573141     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (233)

References (57)
  • 1
    • 0015694748 scopus 로고
    • A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
    • Rowley, J. D. 1973. A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature 243:290.
    • (1973) Nature , vol.243 , pp. 290
    • Rowley, J.D.1
  • 2
    • 0029348008 scopus 로고
    • Abl tyrosine protein kinase
    • Laneuville, P. 1995. Abl tyrosine protein kinase. Semin. Immunol. 7:255.
    • (1995) Semin. Immunol. , vol.7 , pp. 255
    • Laneuville, P.1
  • 3
    • 0026060082 scopus 로고
    • Expression of the chronic myelogenous leukemia-associated p210bcr/abl oncoprotein in a murine IL-3 dependent myeloid cell line
    • Laneuville, P., N. Heisterkamp, and J. Groffen. 1991. Expression of the chronic myelogenous leukemia-associated p210bcr/abl oncoprotein in a murine IL-3 dependent myeloid cell line. Oncogene 6:275.
    • (1991) Oncogene , vol.6 , pp. 275
    • Laneuville, P.1    Heisterkamp, N.2    Groffen, J.3
  • 4
    • 0024242641 scopus 로고
    • bcr-abl oncogene renders myeloid cell line factor independent: Potential autocrine mechanism in chronic myeloid leukemia
    • Hariharan, I. K., J. M. Adams, and S. Cory. 1988. bcr-abl oncogene renders myeloid cell line factor independent: potential autocrine mechanism in chronic myeloid leukemia. Oncogene Res. 3:387.
    • (1988) Oncogene Res. , vol.3 , pp. 387
    • Hariharan, I.K.1    Adams, J.M.2    Cory, S.3
  • 6
    • 0023410428 scopus 로고
    • In vitro transformation immature hematopoietic cells by the p210 BCR/ABL oncogene product of the Philadelphia chromosome
    • McLaughlin, J., E. Chianese, and O. N. Witte. 1987. In vitro transformation immature hematopoietic cells by the p210 BCR/ABL oncogene product of the Philadelphia chromosome. Proc. Natl. Acad. Sci. USA 84:6558.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 6558
    • McLaughlin, J.1    Chianese, E.2    Witte, O.N.3
  • 7
    • 0023696474 scopus 로고
    • Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures
    • Young, J. C., and O. N. Witte. 1988. Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures. Mol. Cell. Biol. 8:4079.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 4079
    • Young, J.C.1    Witte, O.N.2
  • 10
  • 11
    • 0028274049 scopus 로고
    • Expression of bcr-abl abrogates factor-dependent growth of human hematopoietic M07E cells by an autocrine mechanism
    • Sirard, C., P. Laneuville, and J. E. Dick. 1994. Expression of bcr-abl abrogates factor-dependent growth of human hematopoietic M07E cells by an autocrine mechanism. Blood 83:1575.
    • (1994) Blood , vol.83 , pp. 1575
    • Sirard, C.1    Laneuville, P.2    Dick, J.E.3
  • 12
    • 0030071777 scopus 로고    scopus 로고
    • The BCR-ABL oncogene requires both kinase activity and src-homology 2 domain to induce cytokine secretion
    • Anderson, S. M., and J. Mladenovic. 1996. The BCR-ABL oncogene requires both kinase activity and src-homology 2 domain to induce cytokine secretion. Blood 87:238.
    • (1996) Blood , vol.87 , pp. 238
    • Anderson, S.M.1    Mladenovic, J.2
  • 13
    • 0029031668 scopus 로고
    • Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects
    • Harrison, D. A., R. Binari, T. S. Nahreini, M. Gilman, and N. Perrimon. 1995. Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO J. 14:2857.
    • (1995) EMBO J. , vol.14 , pp. 2857
    • Harrison, D.A.1    Binari, R.2    Nahreini, T.S.3    Gilman, M.4    Perrimon, N.5
  • 15
    • 0029916933 scopus 로고    scopus 로고
    • Activation and association of Stat3 with Src in v-Src-transformed cell lines
    • Cao, X., A. Tay, G. R. Guy, and Y. H. Tan. 1996. Activation and association of Stat3 with Src in v-Src-transformed cell lines. Mol. Cell. Biol. 16:1595.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1595
    • Cao, X.1    Tay, A.2    Guy, G.R.3    Tan, Y.H.4
  • 16
    • 0028817880 scopus 로고
    • Jak-STAT signaling induced by the v-abl oncogene
    • Danial, N. N., A. Pernis, and P. B. Rothman. 1995. Jak-STAT signaling induced by the v-abl oncogene. Science 269:1875.
    • (1995) Science , vol.269 , pp. 1875
    • Danial, N.N.1    Pernis, A.2    Rothman, P.B.3
  • 17
    • 0029810923 scopus 로고    scopus 로고
    • Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia
    • Shuai, K., J. Halpern, J. ten Hoeve, X. Rao, and C. L. Sawyers. 1996. Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia. Oncogene 13:247.
    • (1996) Oncogene , vol.13 , pp. 247
    • Shuai, K.1    Halpern, J.2    Ten Hoeve, J.3    Rao, X.4    Sawyers, C.L.5
  • 18
    • 0029863169 scopus 로고
    • Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl
    • Carlesso, N., D. A. Frank, and J. D. Griffin. 1995. Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl. J. Exp. Med 183:811.
    • (1995) J. Exp. Med , vol.183 , pp. 811
    • Carlesso, N.1    Frank, D.A.2    Griffin, J.D.3
  • 19
    • 0000506439 scopus 로고    scopus 로고
    • P210 and p190 BCR/ABL induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members
    • Ilaria, R. L., Jr., and R. A. Van Etten. 1996. P210 and p190 BCR/ABL induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members. J. Biol. Chem. 271:31704.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31704
    • Ilaria Jr., R.L.1    Van Etten, R.A.2
  • 20
    • 24544479290 scopus 로고
    • BCR-Abl p210 and p190 induce constitutive activation of Stat5 in human and murine factor-dependent cell lines
    • Dusanter-Fourt, I., A. Ahmed, T. Bennardo, C. Issad, B. Varet, W. Vainchenker, and A. G. Turhan. 1995. BCR-Abl p210 and p190 induce constitutive activation of Stat5 in human and murine factor-dependent cell lines. Blood 86:166a.
    • (1995) Blood , vol.86
    • Dusanter-Fourt, I.1    Ahmed, A.2    Bennardo, T.3    Issad, C.4    Varet, B.5    Vainchenker, W.6    Turhan, A.G.7
  • 21
    • 0029680564 scopus 로고    scopus 로고
    • P210 Bcr-Abl interacts with the interleukin 3 receptor beta-c subunit and constitutively induces its tyrosine phosphorylation
    • Wilson-Rawls, J., S. Xie, J. Liu, P. Laneuville, and R. B. Arlinghaus. 1996. P210 Bcr-Abl interacts with the interleukin 3 receptor beta-c subunit and constitutively induces its tyrosine phosphorylation. Cancer Res. 56:3426.
    • (1996) Cancer Res. , vol.56 , pp. 3426
    • Wilson-Rawls, J.1    Xie, S.2    Liu, J.3    Laneuville, P.4    Arlinghaus, R.B.5
  • 23
    • 0030003920 scopus 로고    scopus 로고
    • Lack of constitutive activation of Janus kinases and signal transduction and activation of transcription factors in Philadelphia chromosome-positive acute lymphoblastic leukemia
    • Lett.
    • Kanwar, V. S., B. Witthuhn, D. Campana, and J. N. Ihle. 1996. Lack of constitutive activation of Janus kinases and signal transduction and activation of transcription factors in Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood 87:4911 (Lett.).
    • (1996) Blood , vol.87 , pp. 4911
    • Kanwar, V.S.1    Witthuhn, B.2    Campana, D.3    Ihle, J.N.4
  • 24
    • 0024503246 scopus 로고
    • Identification and analysis of human erythropoietin receptors on a factor-dependent cell line, TF-1
    • Kitamura, T., A. Tojo, T. Kuwaki, S. Chiba, K. Miyazono, A. Urabe, and F. Takaku. 1989. Identification and analysis of human erythropoietin receptors on a factor-dependent cell line, TF-1. Blood 73:375.
    • (1989) Blood , vol.73 , pp. 375
    • Kitamura, T.1    Tojo, A.2    Kuwaki, T.3    Chiba, S.4    Miyazono, K.5    Urabe, A.6    Takaku, F.7
  • 26
    • 0023196145 scopus 로고
    • Cell lines and peripheral blood leukocytes derived from individuals with chronic myelogenous leukemia display virtually identical proteins phosphorylated on tyrosine residues
    • Huhn, R. D., M. R. Posner, S. I. Rayter, J. G. Foulkes, and A. R. Frackelton, Jr. 1987. Cell lines and peripheral blood leukocytes derived from individuals with chronic myelogenous leukemia display virtually identical proteins phosphorylated on tyrosine residues. Proc. Natl. Acad. Sci. USA 84:4408.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 4408
    • Huhn, R.D.1    Posner, M.R.2    Rayter, S.I.3    Foulkes, J.G.4    Frackelton Jr., A.R.5
  • 27
    • 0016640079 scopus 로고
    • Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome
    • Lozzio, C. B., and B. B. Lozzio. 1975. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood 45:321.
    • (1975) Blood , vol.45 , pp. 321
    • Lozzio, C.B.1    Lozzio, B.B.2
  • 29
    • 0025005197 scopus 로고
    • A bioassay for the measurement of human interleukin-4
    • Siegel, J. P., and H. S. Mostowski. 1990. A bioassay for the measurement of human interleukin-4. J. Immunol. Methods 132:287.
    • (1990) J. Immunol. Methods , vol.132 , pp. 287
    • Siegel, J.P.1    Mostowski, H.S.2
  • 30
    • 0025750139 scopus 로고
    • The Epstein-Barr virus nuclear protein encoded by the leader of the EBNA RNAs is important in B-lymphocyte transformation
    • Mannick, J. B., J. I. Cohen, M. Birkenbach, A. Marchini, and E. Kieff. 1991. The Epstein-Barr virus nuclear protein encoded by the leader of the EBNA RNAs is important in B-lymphocyte transformation. J. Virol. 65:6826.
    • (1991) J. Virol. , vol.65 , pp. 6826
    • Mannick, J.B.1    Cohen, J.I.2    Birkenbach, M.3    Marchini, A.4    Kieff, E.5
  • 31
    • 0028658374 scopus 로고
    • Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation
    • Mannick, J. B., K. Asano, K. Izumi, E. Kieff, and J. S. Stamler. 1994. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Cell 79:1137.
    • (1994) Cell , vol.79 , pp. 1137
    • Mannick, J.B.1    Asano, K.2    Izumi, K.3    Kieff, E.4    Stamler, J.S.5
  • 32
    • 0015509615 scopus 로고
    • Sensitivity of Epstein-Barr virus (EBV) producer and non-producer human lymphoblastoid cell lines to superinfection with EB-virus
    • Klein, G., L. Dombos, and B. Gothoskar. 1972. Sensitivity of Epstein-Barr virus (EBV) producer and non-producer human lymphoblastoid cell lines to superinfection with EB-virus. Int. J. Cancer 10:44.
    • (1972) Int. J. Cancer , vol.10 , pp. 44
    • Klein, G.1    Dombos, L.2    Gothoskar, B.3
  • 33
    • 0020038653 scopus 로고
    • Immunoglobulin heavy chain expression and class-switching in a murine leukemia cell line
    • Alt, F. W., N. Rosenberg, R. Casanova, E. Thomas, and D. Baltimore. 1982. Immunoglobulin heavy chain expression and class-switching in a murine leukemia cell line. Nature 296:325.
    • (1982) Nature , vol.296 , pp. 325
    • Alt, F.W.1    Rosenberg, N.2    Casanova, R.3    Thomas, E.4    Baltimore, D.5
  • 34
    • 0029087475 scopus 로고
    • Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene
    • Goga, A., J. McLaughlin, D. E. Afar, D. C. Saffran, and O. N. Witte. 1995. Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene. Cell 82:981.
    • (1995) Cell , vol.82 , pp. 981
    • Goga, A.1    McLaughlin, J.2    Afar, D.E.3    Saffran, D.C.4    Witte, O.N.5
  • 35
    • 0028097932 scopus 로고
    • Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene
    • Pine, R., A. Canova, and C. Schindler. 1994. Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene. EMBO J. 13:158.
    • (1994) EMBO J. , vol.13 , pp. 158
    • Pine, R.1    Canova, A.2    Schindler, C.3
  • 36
    • 0027771191 scopus 로고
    • Characterization of a pathway for ciliary neurotropic factor signaling to the nucleus
    • Bonni, A., D. A. Frank, C. Schindler, and M. E. Greenberg. 1992. Characterization of a pathway for ciliary neurotropic factor signaling to the nucleus. Science 262:1575.
    • (1992) Science , vol.262 , pp. 1575
    • Bonni, A.1    Frank, D.A.2    Schindler, C.3    Greenberg, M.E.4
  • 37
    • 0027240840 scopus 로고
    • The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage
    • Eilers, A., D. Seegert, C. Schindler, M. Baccarini, and T. Decker. 1993. The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage. Mol. Cell. Biol. 13:3245.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3245
    • Eilers, A.1    Seegert, D.2    Schindler, C.3    Baccarini, M.4    Decker, T.5
  • 38
    • 0026770248 scopus 로고
    • Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
    • Schindler, C., K. Shuai, V. R. Prezioso, and J. E. Darnell, Jr. 1992. Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257:809.
    • (1992) Science , vol.257 , pp. 809
    • Schindler, C.1    Shuai, K.2    Prezioso, V.R.3    Darnell Jr., J.E.4
  • 39
    • 0026725868 scopus 로고
    • Proteins of transcription factor ISGF-3: One gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon alpha
    • Schindler, C., X. Y. Fu, T. Improta, R. Aebersold, and J. Darnell, Jr. 1992. a. Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc. Natl. Acad. Sci. USA 89:7836.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7836
    • Schindler, C.1    Fu, X.Y.2    Improta, T.3    Aebersold, R.4    Darnell Jr., J.5
  • 42
    • 0028219966 scopus 로고
    • An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth
    • Keegan, A. D., K. Nelms, M. White, L. M. Wang, J. H. Pierce, and W. E. Paul. 1994. An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth. Cell 76:811.
    • (1994) Cell , vol.76 , pp. 811
    • Keegan, A.D.1    Nelms, K.2    White, M.3    Wang, L.M.4    Pierce, J.H.5    Paul, W.E.6
  • 44
    • 0027094764 scopus 로고
    • IL-4 activates a distinct signal transduction cascade from IL-3 in factor-dependent myeloid cells
    • Wang, L. M., A. D. Keegan, W. E. Paul, M. A. Heidaran, J. S. Gutkind, and J. H. Pierce. 1992. IL-4 activates a distinct signal transduction cascade from IL-3 in factor-dependent myeloid cells. EMBO J 11:4899.
    • (1992) EMBO J , vol.11 , pp. 4899
    • Wang, L.M.1    Keegan, A.D.2    Paul, W.E.3    Heidaran, M.A.4    Gutkind, J.S.5    Pierce, J.H.6
  • 46
    • 0025282332 scopus 로고
    • Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 T cells
    • Yu-Lee, L. Y., J. A. Hrachovy, A. M. Stevens, and L. A. Schwarz. 1990. Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 T cells. Mol. Cell. Biol. 10:3087.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 3087
    • Yu-Lee, L.Y.1    Hrachovy, J.A.2    Stevens, A.M.3    Schwarz, L.A.4
  • 47
    • 0028211553 scopus 로고
    • The signalling pathways of interleukin-6 and gamma Interferon converge by the activation of different transcription factors which bind to common responsive DNA elements
    • Yuan, J., U. M. Wegenka, C. Lutticken, J. Buschmann, T. Decker, C. Schindler, P. C. Heinrich, and F. Horn. 1994. The signalling pathways of interleukin-6 and gamma Interferon converge by the activation of different transcription factors which bind to common responsive DNA elements. Mol. Cell. Biol. 14:1657.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1657
    • Yuan, J.1    Wegenka, U.M.2    Lutticken, C.3    Buschmann, J.4    Decker, T.5    Schindler, C.6    Heinrich, P.C.7    Horn, F.8
  • 48
    • 0029045866 scopus 로고
    • Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5
    • Mui, A. L., H. Wakao, N. Harada, A. M. O'Farrell, and A. Miyajima. 1995. Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5. J. Leukocyte Biol. 57:799.
    • (1995) J. Leukocyte Biol. , vol.57 , pp. 799
    • Mui, A.L.1    Wakao, H.2    Harada, N.3    O'Farrell, A.M.4    Miyajima, A.5
  • 49
    • 0028963550 scopus 로고
    • Interleukin-3. granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs
    • Mui, A. L., H. Wakao, A. M. O'Farrell, N. Harada, and A. Miyajima. 1995. Interleukin-3. granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J. 14:1166.
    • (1995) EMBO J. , vol.14 , pp. 1166
    • Mui, A.L.1    Wakao, H.2    O'Farrell, A.M.3    Harada, N.4    Miyajima, A.5
  • 52
    • 0028931604 scopus 로고
    • Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
    • Stahl, N., T. J. Farrugella, T. G. Boulton, Z. Zhong, J. E. Darnell, Jr., and G. D. Yancopoulos. 1995. Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science 267:1349.
    • (1995) Science , vol.267 , pp. 1349
    • Stahl, N.1    Farrugella, T.J.2    Boulton, T.G.3    Zhong, Z.4    Darnell Jr., J.E.5    Yancopoulos, G.D.6
  • 53
    • 0028946158 scopus 로고
    • Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway
    • Heim, M. H., I. M. Kerr, G. R. Stark, and J. E. Darnell, Jr. 1995. Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway. Science 267:1347.
    • (1995) Science , vol.267 , pp. 1347
    • Heim, M.H.1    Kerr, I.M.2    Stark, G.R.3    Darnell Jr., J.E.4
  • 54
    • 0028411110 scopus 로고
    • Abl-mediated transformation, immunoglobulin gene rearrangements and arrest of B lymphocyte differentiation
    • Rosenberg, N. 1994. Abl-mediated transformation, immunoglobulin gene rearrangements and arrest of B lymphocyte differentiation. Semin. Cancer Biol. 5:95.
    • (1994) Semin. Cancer Biol. , vol.5 , pp. 95
    • Rosenberg, N.1
  • 55
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo, T. G., A. Pendergast, A. J. Muller, and O. N. Witte. 1990. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science 247: 1079.
    • (1990) Science , vol.247 , pp. 1079
    • Lugo, T.G.1    Pendergast, A.2    Muller, A.J.3    Witte, O.N.4
  • 56
    • 0028972103 scopus 로고
    • The SH2 domain of P210 BCR/ABL is not required for the transformation of hematopoietic factor-dependent cells
    • Ilaria, R. L., Jr., and R. A. Van Etten. 1995. The SH2 domain of P210 BCR/ABL is not required for the transformation of hematopoietic factor-dependent cells. Blood 86:3897.
    • (1995) Blood , vol.86 , pp. 3897
    • Ilaria Jr., R.L.1    Van Etten, R.A.2


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