STAT-related transcription factors are constitutively activated in peripheral blood cells from acute leukemia patients

Blood

Volumn 87, Issue 5, 1996, Pages 1692-1697

  Gouilleux Gruart, Valérie ^a   Gouilleux, Fabrice ^b   Desaint, Corinne ^b   Claisse, Jean François ^b   Capiod, Jean Claude ^b   Delobel, Jacques ^b   Weber Nordt, Renate ^b   Dusanter Fourt, Isabelle ^b   Dreyfus, François ^b   Groner, Bernd ^b   Prin, Lionel ^b  

^a AMIENS UNIVERSITY HOSPITAL   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA CASEIN; DNA; NUCLEAR PROTEIN; OLIGONUCLEOTIDE; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; HUMAN; HUMAN CELL; LEUKOCYTE; OLIGONUCLEOTIDE PROBE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 13344279401     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.5.1692.bloodjournal8751692     Document Type: Article

References (35)

1. Darnell JE, Kerr IM, Stark GR: JAK-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415, 1994
2. Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, Silvennoinen O: Signaling by the cytokine receptor superfamily: JAKs and STATs. Trends Biochem Sci 19:222, 1994
3. Wilks AF, Harpur AG: Cytokine signal transduction and the JAK family of protein tyrosine kinases. Bioessays 16:313, 1994
4. Briscoe J, Guschin D, Müller M: Just another signaling pathway. Curr Biol 4:1033, 1994
5. Taniguchi T: Cytokine signaling through non receptor protein tyrosine kinases. Science 268:251, 1995
6. Shuai K, Schindler C, Prezioso VR, Darnell JE: Activation of transcription by IFN-γ: Tyrosine phosphorylation of a 91-kD DNA-binding protein. Science 259:1808, 1992
7. Schindler C, Fu XY, Improta T, Aebersold R, Darnell JE: Proteins of transcription factor ISGF-3: One gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon α. Proc Natl Acad Sci USA 89:7836, 1992
8. Fu XY, Schindler C, Improta T, Aebersold R, Darnell JE: The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction. Proc Natl Acad Sci USA 89:7840, 1992
9. Zhong Z, Wen Z, Darnell JE: Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264:95, 1994
10. Akira S, Nishio Y, Inoue M, Wang X-J, Wei S, Matsusaka T, Yoshida K, Sudo T, Naruto M, Kishimoto T: Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 77:63, 1994
11. Jacobson NG, Szabo Sj, Weber-Nordt RM, Zhong Z, Schreiber RD, Darnell JE, Murphy KM: Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphrylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp Med 181:1755. 1995
12. Tian S-S, Lamb P, Seidel MH, Stein RB, Rosen J: Rapid activation of the Stat3 transcription factor by granulocyte colony-stimulating factor. Blood 84:1760, 1994
13. Yamamoto K, Quelle FW, Thierfelder WE, Kreider BL, Gilbert DJ, Jenkins NA, Copeland NG, Silvennoinen O, Ihle JN: STAT4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. Mol Cell Biol 14:4342, 1994
14. Wakao H, Gouilleux F, Groner B: Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response. EMBO J 13:2182, 1994
15. Gouilleux F, Pallard C, Dusanter-Fourt I, Wakao H, Haldosen L-A, Norstedt G, Levy D, Groner B: Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-STAT5 DNA-binding activity. EMBO J 14:2005, 1995
16. Wood TJJ, Sliva D, Lobie PE, Pircher TJ, Gouilleux F, Wakao H, Gustafsson J-A, Groner B, Norstedt G, Haldosén L-A: Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/STAT5. J Biol Chem 270:9448, 1995
17. Pallard C, Gouilleux F, Benit L, Cocault L, Souyri M, Levy D, Groner B, Gisselbrecht S, Dusanter-Fourt I: Thrombopoietin activates a STAT5-like factor in hematopoietic cells. EMBO J 14:2847, 1995
18. Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC: Signaling through the interleukin 2 receptor β chain activates a STAT5-like DNA-binding activity. Proc Natl Acad Sci USA 92:7192, 1995
19. Wakao H, Harada N, Kitamura T, Mui ALF, Miyajima A: Interleukin 2 (IL-2) and erythropoietin (EPO) activate STAT5/MGF via distinct pathways. EMBO J 14:2527, 1995
20. Mui ALF, Wakao II, O'Farrell AM, Harada N, Miyajima A: Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J 14.1166, 1995
21. Azam M, Erdjument-Bromage H, Kreider BL, Xia M, Quelle F, Basu R, Saris C, Tempst P, Ihle JN, Schindler C: Interleukin-3 signals through multiple isoforms of Stat5. EMBO J 14:1402, 1995
22. Liu X, Robinson GW, Gouilleux F, Groner B, Hennighausen L: Cloning and expression of STAT5 and an additional homologue (STAT5b) involved in prolactin signal transduction in mouse mammary tissue. Proc Natl Acad Sci USA 92.8831, 1995
23. Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, McKnight SL. An interleukin-4-induced transcription factor: IL-4 Stat. Science 265:1701, 1994
24. Quelle FW, Shimoda K, Thierfelder W, Fischer C, Kim A, Ruben SM, Cleveland JI, Pierce JH, Keegan AD, Nelms K, Paul WE, Ihle JN: Cloning of murine STAT6 and human STAT6, STAT proteins that are tyrosine phosphorylated in responses to IL4 and IL3 but are not required for mitogenesis. Mol Cell Biol 15.3336, 1995
25. Tion-1 JAK kinase causes leukemia-like hematopoietic defects. EMBO J 14:1412, 1995
26. Harrison DA, Binari R, Nahreini TS, Gilman M, Perrimon N: Activation of a Drosophilia Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO J 14:2857, 1995
27. Migone T-S, Lin J-X, Cereseto A, Mulloy JC, O'Shea JJ, Franchini G, Leonard W: Constitutively activated JAK-STAT pathway in T cells transformed with HTLV-1 Science 269:79, 1995
28. Benett JM, Catovski D, Daniel M-T, Flandrin G, Galton DAG, Gralnick HR, Sultan C: Proposal for the classification of the acute leukemia (FAB cooperation group). Br J Haematol 33:451, 1976
29. Schaefer TS, Sanders LK, Nathans D: Cooperative transcriptional activity of Jun and Stat3β, a short form of Stat3. Proc Natl Acad Sci USA 92:9097, 1995
30. Watson CJ, Miller WR: Elevated levels of Stat family of transcription factors in breast carcinoma nuclear extracts. Br J Cancer 71:840, 1995
31. Happ B, Hynes NE, Groner B: Ha-ras and v-raf, but not int-2 and c-myc, interfere with the lactogenic hormone dependent activation of the mammary gland specific transcription factor MGF. Cell Growth Differ 4:9, 1993
32. Yu C-L, Meyer DJ, Campbell GS, Larner AC, Carter-Su C, Schwartz J, Jove R: Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 269:81, 1995
33. Konopka JB, Watanabe SM, Witte ON: An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Cell 37:1035, 1984
34. Lu D, Liu J, Campbell M, Guo JQ, Heisterkamp N, Groffen J, Canaai E, Arlinghaus R: Tyrosine phosphorylation of P160 BCR by P210 BCR-ABL. Blood 82:1257, 1993
35. Danial NN, Pernis A, Rothman PB: Jak-STAT signaling induced by the v-abl oncogene. Science 269:1875, 1995