메뉴 건너뛰기




Volumn 9, Issue 1-2, 2003, Pages 10-17

Interleukin- 10 deficiency increases atherosclerosis, thrombosis, and low-density lipoproteins in apolipoprotein E knockout mice

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; GELATINASE A; GELATINASE B; INTERLEUKIN 10; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MATRIX METALLOPROTEINASE; PROCOAGULANT; THROMBIN; THROMBOPLASTIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 0038544576     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03402102     Document Type: Article
Times cited : (296)

References (52)
  • 2
    • 0033569130 scopus 로고    scopus 로고
    • Protective role of interleukin-10 in atherosclerosis
    • Mallat Z et al. (1999) Protective role of interleukin-10 in atherosclerosis. Circ. Res. 85:e17-24.
    • (1999) Circ. Res. , vol.85
    • Mallat, Z.1
  • 3
    • 0037205317 scopus 로고    scopus 로고
    • Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient mice by altering lymphocyte and macrophage phenotypes
    • Pinderski LJ et al. (2002) Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient mice by altering lymphocyte and macrophage phenotypes. Circ. Res. 90:1064-71.
    • (2002) Circ. Res. , vol.90 , pp. 1064-1071
    • Pinderski, L.J.1
  • 4
    • 0000614773 scopus 로고    scopus 로고
    • Interleukin-10 blocks atherosclerotic events in vitro and in vivo
    • Pinderski Oslund LJ et al. (1999) Interleukin-10 blocks atherosclerotic events in vitro and in vivo. Arterioscler. Thromb. Vasc. Biol. 19:2847-53.
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 2847-2853
    • Pinderski Oslund, L.J.1
  • 5
    • 0035838424 scopus 로고    scopus 로고
    • In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice
    • Laurat E et al. (2001) In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice. Circulation 104:197-202.
    • (2001) Circulation , vol.104 , pp. 197-202
    • Laurat, E.1
  • 6
    • 0036193513 scopus 로고    scopus 로고
    • Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice
    • Caligiuri G, Nicoletti A, Poirier B, Hansson GK. (2002) Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice. J. Clin. Invest. 109:745-53.
    • (2002) J. Clin. Invest. , vol.109 , pp. 745-753
    • Caligiurt, G.1    Nicoletti, A.2    Poirier, B.3    Hansson, G.K.4
  • 7
    • 0027491655 scopus 로고
    • Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming
    • Seder RA, Gazzinelli R, Sher A, Paul WE. (1993) Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming. Proc. Natl. Acad. Sci. U.S.A. 90:10188-92.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 10188-10192
    • Seder, R.A.1    Gazzinelli, R.2    Sher, A.3    Paul, W.E.4
  • 8
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL. (1989) TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-73.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 9
    • 0028890866 scopus 로고
    • Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases
    • Liblau RS, Singer SM, McDevitt HO. (1995) Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol. Today 16:34-8.
    • (1995) Immunol. Today , vol.16 , pp. 34-38
    • Liblau, R.S.1    Singer, S.M.2    McDevitt, H.O.3
  • 10
    • 0033015659 scopus 로고    scopus 로고
    • Expression of interleukin-10 in advanced human atherosclerotic plaques: Relation to inducible nitric oxide synthase expression and cell death
    • Mallat Z et al. Expression of interleukin-10 in advanced human atherosclerotic plaques: relation to inducible nitric oxide synthase expression and cell death. Arterioscler. Thromb. Vasc. Biol. 19:611-6.
    • Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 611-616
    • Mallat, Z.1
  • 11
    • 15844415074 scopus 로고    scopus 로고
    • Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis
    • Uyemura K et al. (1996) Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis. J. Clin. Invest. 97:2130-8.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2130-2138
    • Uyemura, K.1
  • 12
    • 0024416254 scopus 로고
    • Detection of activated T lymphocytes in the human atherosclerotic plaque
    • Honsson GK, Holm J, Jonasson L. (1989) Detection of activated T lymphocytes in the human atherosclerotic plaque. Am. J. Pathol. 135:169-75.
    • (1989) Am. J. Pathol. , vol.135 , pp. 169-175
    • Honsson, G.K.1    Holm, J.2    Jonasson, L.3
  • 13
    • 0032522995 scopus 로고    scopus 로고
    • Hypercholesterolemia is associoted with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice
    • Zhou X, Paulsson G, Stemme S, Honsson GK. (1998) Hypercholesterolemia is associoted with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice. J. Clin. Invest. 101:1717-25.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1717-1725
    • Zhou, X.1    Paulsson, G.2    Stemme, S.3    Honsson, G.K.4
  • 14
    • 0032976126 scopus 로고    scopus 로고
    • The role of interleukin 12 in the development of atherosclerosis in ApoE-deficient mice
    • Lee TS, Yen HC, Pan CC, Chau LY. (1999) The role of interleukin 12 in the development of atherosclerosis in ApoE-deficient mice. Arterioscler. Thromb. Vasc. Biol. 19:734-42.
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 734-742
    • Lee, T.S.1    Yen, H.C.2    Pan, C.C.3    Chau, L.Y.4
  • 15
    • 0030974188 scopus 로고    scopus 로고
    • IFN-γ potentiates otherosclerosis in ApoE knockout mice
    • Gupta S et al. (1997) IFN-γ potentiates otherosclerosis in ApoE knockout mice. J. Clin. Invest. 99:2752-61.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2752-2761
    • Gupta, S.1
  • 17
    • 0034720851 scopus 로고    scopus 로고
    • Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes
    • Liuzzo G et al. (2000) Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes. Circulation. 101:2883-8.
    • (2000) Circulation , vol.101 , pp. 2883-2888
    • Liuzzo, G.1
  • 18
    • 0024811224 scopus 로고
    • Interferon γ inhibits both proliferation and expression of differentiation-specific α-smooth muscle actin in arterial smooth muscle cells
    • Hansson GK, Hellstrand M, Rymo L, Rubbia L, Gabbiani G. (1989) Interferon γ inhibits both proliferation and expression of differentiation-specific α-smooth muscle actin in arterial smooth muscle cells. J. Exp. Med. 170:1595-608.
    • (1989) J. Exp. Med. , vol.170 , pp. 1595-1608
    • Hansson, G.K.1    Hellstrand, M.2    Rymo, L.3    Rubbia, L.4    Gabbiani, G.5
  • 19
    • 0025800329 scopus 로고
    • Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells
    • Amento EP, Ehsani N, Palmer H, Libby P. (1991) Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells. Arterioscl. Thromb. 11:1223-30.
    • (1991) Arterioscl. Thromb. , vol.11 , pp. 1223-1230
    • Amento, E.P.1    Ehsani, N.2    Palmer, H.3    Libby, P.4
  • 20
    • 0029054734 scopus 로고
    • Molecular bases of the acute coronary syndromes
    • Libby P. (1995) Molecular bases of the acute coronary syndromes. Circulation. 91:2844-50.
    • (1995) Circulation , vol.91 , pp. 2844-2850
    • Libby, P.1
  • 21
    • 0030292766 scopus 로고    scopus 로고
    • TNF-α and IL-1β selectively induce expression of 92-kDa gelatinase by human macrophages
    • Saren P, Welgus HG, Kovanen PT. (1996) TNF-α and IL-1β selectively induce expression of 92-kDa gelatinase by human macrophages. J. Immunol. 157:4159-65.
    • (1996) J. Immunol. , vol.157 , pp. 4159-4165
    • Saren, P.1    Welgus, H.G.2    Kovanen, P.T.3
  • 22
    • 0028906905 scopus 로고
    • Interferon-γ modulates the fibrinolytic response in cultured human endothelial cells
    • Amman V, Stemme S, Rymo L, Risberg B. (1995) Interferon-γ modulates the fibrinolytic response in cultured human endothelial cells. Thromb. Res. 77:431-40.
    • (1995) Thromb. Res. , vol.77 , pp. 431-440
    • Arnman, V.1    Stemme, S.2    Rymo, L.3    Risberg, B.4
  • 23
    • 0030587084 scopus 로고    scopus 로고
    • IFN-γ inhibits thrombin- and endotoxin-induced plasminogen activator inhibitor type 1 in human endothelial cells
    • Gallicchio M, Hufnagl P, Wojta J, Tipping P. (1996) IFN-γ inhibits thrombin- and endotoxin-induced plasminogen activator inhibitor type 1 in human endothelial cells. J. Immunol. 157:2610-7.
    • (1996) J. Immunol. , vol.157 , pp. 2610-2617
    • Gallicchio, M.1    Hufnagl, P.2    Wojta, J.3    Tipping, P.4
  • 24
    • 0032953206 scopus 로고    scopus 로고
    • Interleukin 10 (IL-10) inhibition of primary human prostate cell-induced angiogenesis: IL-10 stimulation of tissue inhibitor of metalloproteinase-1 and inhibition of matrix metalloproteinase (MMP)-2/MMP-9 secretion
    • Stearns ME, Rhim J, Wang M. (1999) Interleukin 10 (IL-10) inhibition of primary human prostate cell-induced angiogenesis: IL-10 stimulation of tissue inhibitor of metalloproteinase-1 and inhibition of matrix metalloproteinase (MMP)-2/MMP-9 secretion. Clin. Cancer Res. 5:189-96.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 189-196
    • Stearns, M.E.1    Rhim, J.2    Wang, M.3
  • 25
    • 0027423733 scopus 로고
    • Interleukin-10 inhibits endotoxin-induced tissue factor mRNA production by human monocytes
    • Ramani M et al. (1993) Interleukin-10 inhibits endotoxin-induced tissue factor mRNA production by human monocytes. FEBS Lett. 334:114-6.
    • (1993) FEBS Lett. , vol.334 , pp. 114-116
    • Ramani, M.1
  • 26
    • 0030971484 scopus 로고    scopus 로고
    • Interleukin-10 inhibits activation of coagulation and fibrinolysis during human endotoxemia
    • Pajkrf D et al. (1997) Interleukin-10 inhibits activation of coagulation and fibrinolysis during human endotoxemia. Blood. 89:2701-5.
    • (1997) Blood , vol.89 , pp. 2701-2705
    • Pajkrf, D.1
  • 27
    • 0032761854 scopus 로고    scopus 로고
    • Interleukin-10 (IL-10) augments allograft arterial disease: Paradoxical effects of IL-10 in vivo
    • Furukawa Y, Becker G, Stinn JL, Shimizu K, Libby P, Mitchell RN. (1999) Interleukin-10 (IL-10) augments allograft arterial disease: paradoxical effects of IL-10 in vivo. Am. J. Pathol. 155:1929-39.
    • (1999) Am. J. Pathol. , vol.155 , pp. 1929-1939
    • Furukawa, Y.1    Becker, G.2    Stinn, J.L.3    Shimizu, K.4    Libby, P.5    Mitchell, R.N.6
  • 29
    • 0033650847 scopus 로고    scopus 로고
    • Thyroid hormone receptor β-deficient mice show complete loss of the normal cholesterol 7α-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol
    • Gullberg H, Rudling M, Forrest D, Angelin B, Vennstrom B. (2000) Thyroid hormone receptor β-deficient mice show complete loss of the normal cholesterol 7α-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol. Mol. Endocrinol. 14:1739-49.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1739-1749
    • Gullberg, H.1    Rudling, M.2    Forrest, D.3    Angelin, B.4    Vennstrom, B.5
  • 30
    • 0028877056 scopus 로고
    • Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations
    • Openshaw P et al. (1995) Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J. Exp. Med. 182:1357-67.
    • (1995) J. Exp. Med. , vol.182 , pp. 1357-1367
    • Openshaw, P.1
  • 31
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. (1993) Interleukin-10-deficient mice develop chronic enterocolitis. Cell. 75:263-74.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 32
    • 8944251136 scopus 로고    scopus 로고
    • Temporal relation between ischemic episodes and activation of the coagulation system in unstable angina
    • Biasucci LM et al. (1996) Temporal relation between ischemic episodes and activation of the coagulation system in unstable angina. Circulation. 93:2121-7.
    • (1996) Circulation , vol.93 , pp. 2121-2127
    • Biasucci, L.M.1
  • 34
    • 0032774697 scopus 로고    scopus 로고
    • Effects of sex and age on atherosclerosis and autoimmunity in apoE deficient mice
    • Caligiuri G, Nicoletti A, Zhou X, Tomberg I, Hansson GK. (1999) Effects of sex and age on atherosclerosis and autoimmunity in apoE deficient mice. Atherosclerosis. 145:301-8.
    • (1999) Atherosclerosis , vol.145 , pp. 301-308
    • Caligiuri, G.1    Nicoletti, A.2    Zhou, X.3    Tornberg, I.4    Hansson, G.K.5
  • 36
  • 37
    • 0026351574 scopus 로고
    • Differential effects of oestrogen in murine lupus: Acceleration of glomerulonephritis and amelioration of T cell-mediated lesions
    • Carlsten H, Nilsson N, Jonsson R, Tarkowski A. (1991) Differential effects of oestrogen in murine lupus: acceleration of glomerulonephritis and amelioration of T cell-mediated lesions. J. Autoimmun. 4:845-56.
    • (1991) J. Autoimmun. , vol.4 , pp. 845-856
    • Carlsten, H.1    Nilsson, N.2    Jonsson, R.3    Tarkowski, A.4
  • 38
    • 0026658133 scopus 로고
    • Estrogen accelerates immune complex glomerulonephritis but ameliorates T cell-mediated vasculitis and sialadenitis in autoimmune MRL Ipr/Ipr mice
    • Carlsten H et al. (1992) Estrogen accelerates immune complex glomerulonephritis but ameliorates T cell-mediated vasculitis and sialadenitis in autoimmune MRL Ipr/Ipr mice. Cell. Immunol. 144:190-202.
    • (1992) Cell. Immunol. , vol.144 , pp. 190-202
    • Carlsten, H.1
  • 39
    • 0027359538 scopus 로고
    • Histocompatibility complex gene products and exposure to oestrogen: Two independent disease accelerating factors in murine lupus
    • Carlsten H, Tarkowski A. (1993) Histocompatibility complex gene products and exposure to oestrogen: two independent disease accelerating factors in murine lupus. Scand. J. Immunol. 38:341-7.
    • (1993) Scand. J. Immunol. , vol.38 , pp. 341-347
    • Carlsten, H.1    Tarkowski, A.2
  • 40
    • 0024822798 scopus 로고
    • Oestrogen is a potent immunomodulator of murine experimental rheumatoid disease
    • Holmdahl R, Carlsten H, Jansson L, Larsson P. (1989) Oestrogen is a potent immunomodulator of murine experimental rheumatoid disease. Br. J. Rheumatol. 28:54-8.
    • (1989) Br. J. Rheumatol. , vol.28 , pp. 54-58
    • Holmdahl, R.1    Carlsten, H.2    Jansson, L.3    Larsson, P.4
  • 41
    • 0033949866 scopus 로고    scopus 로고
    • Sex hormone levels correlate with the activity of cytokine-secreting cells in vivo
    • Verthelyi D, Klinman DM. (2000) Sex hormone levels correlate with the activity of cytokine-secreting cells in vivo. Immunology 100:384-90.
    • (2000) Immunology , vol.100 , pp. 384-390
    • Verthelyi, D.1    Klinman, D.M.2
  • 42
    • 0025003076 scopus 로고
    • Metabolic responses to cachectin/TNF. A brief review
    • Tracey KJ, Cerami A. (1990) Metabolic responses to cachectin/TNF. A brief review. Ann. N.Y. Acad. Sci. 587:325-31.
    • (1990) Ann. N.Y. Acad. Sci. , vol.587 , pp. 325-331
    • Tracey, K.J.1    Cerami, A.2
  • 43
    • 0031458498 scopus 로고    scopus 로고
    • Lipoprotein heterogeneity and apolipoprotein B metabolism
    • Packard CJ, Shepherd J. (1997) Lipoprotein heterogeneity and apolipoprotein B metabolism. Arterioscler. Thromb. Vasc. Biol. 17:3542-56.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 3542-3556
    • Packard, C.J.1    Shepherd, J.2
  • 44
    • 0035723938 scopus 로고    scopus 로고
    • Lipoprotein size and atherosclerosis susceptibility in ApoE(-/-) and LDLR(-/-) mice
    • Veniant MM, Withycombe S, Young SG. (2001) Lipoprotein size and atherosclerosis susceptibility in ApoE(-/-) and LDLR(-/-) mice. Arterioscler. Thromb. Vasc. Biol. 21:1567-70.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 1567-1570
    • Veniant, M.M.1    Withycombe, S.2    Young, S.G.3
  • 45
    • 0035195656 scopus 로고    scopus 로고
    • Increased prevalence of atherosclerosis in patients with medium term rheumatoid arthritis
    • Jonsson SW et al. (2001) Increased prevalence of atherosclerosis in patients with medium term rheumatoid arthritis. J. Rheumatol. 28:2597-602.
    • (2001) J. Rheumatol. , vol.28 , pp. 2597-2602
    • Jonsson, S.W.1
  • 46
    • 0035676862 scopus 로고    scopus 로고
    • Elevated levels of small, low-density lipoprotein with high affinity for arterial matrix components in patients with rheumatoid arthritis: Possible contribution of phospholipase A2 to this atherogenic profile
    • Hurt-Camejo E et al. (2001) Elevated levels of small, low-density lipoprotein with high affinity for arterial matrix components in patients with rheumatoid arthritis: possible contribution of phospholipase A2 to this atherogenic profile. Arthritis Rheum. 44:2761-7.
    • (2001) Arthritis Rheum , vol.44 , pp. 2761-2767
    • Hurt-Camejo, E.1
  • 47
    • 0030952954 scopus 로고    scopus 로고
    • Tissue-factor antigen and activity in human coronary atherosclerotic plaques
    • Ardissino D et al. (1997) Tissue-factor antigen and activity in human coronary atherosclerotic plaques. Lancet. 349:769-71.
    • (1997) Lancet , vol.349 , pp. 769-771
    • Ardissino, D.1
  • 48
    • 0032145662 scopus 로고    scopus 로고
    • Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes
    • Kai H et al. (1998) Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes. J. Am. Coll. Cardiol. 32:368-72.
    • (1998) J. Am. Coll. Cardiol. , vol.32 , pp. 368-372
    • Kai, H.1
  • 49
    • 0035129613 scopus 로고    scopus 로고
    • Atherosclerotic plaque rupture in the apolipoprotein E knockout mouse
    • Johnson JL, Jackson CL. (2001) Atherosclerotic plaque rupture in the apolipoprotein E knockout mouse. Atherosclerosis. 154:399-406.
    • (2001) Atherosclerosis , vol.154 , pp. 399-406
    • Johnson, J.L.1    Jackson, C.L.2
  • 50
    • 0033669676 scopus 로고    scopus 로고
    • Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse
    • Rosenfeld ME et al. (2000) Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse. Arterioscler. Thromb. Vasc. Biol. 20:2587-92.
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 2587-2592
    • Rosenfeld, M.E.1
  • 51
    • 0029113033 scopus 로고
    • Heightened thrombin formation but normal plasma levels of activated factor VII in patients with acute coronary syndromes
    • Merlini PA et al. (1995) Heightened thrombin formation but normal plasma levels of activated factor VII in patients with acute coronary syndromes. Arterioscler. Thromb. Vasc. Biol. 15:1675-9.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 1675-1679
    • Merlini, P.A.1
  • 52
    • 0032146691 scopus 로고    scopus 로고
    • IL-10 regulates thrombus-induced vein wall inflammation and thrombosis
    • Downing LJ et al. (1998) IL-10 regulates thrombus-induced vein wall inflammation and thrombosis. J Immunol. 161:1471-6.
    • (1998) J. Immunol. , vol.161 , pp. 1471-1476
    • Downing, L.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.