Inhibition of tumor necrosis factor α-mediated NFκB activation and leukocyte adhesion, with enhanced endothelial apoptosis, by G protein-linked receptor (TP) ligands

Journal of Biological Chemistry

Volumn 278, Issue 14, 2003, Pages 11858-11866

  Ashton, Anthony W ^a   Ware, Gabriel M ^a   Kaul, Dhananjaya K ^a   Ware, J Anthony ^a,b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; PROTEINS;

TUMOR NECROSIS FACTOR (TNF);

TUMORS;

1 [7 [3 [3 HYDROXY 4 (4' IODOPHENOXY)] 1 BUTENYL] 7 OXABICYCLO[2.2.1]HEPTAN 2 YL] 5' HEPTANOIC ACID]; ANTISENSE OLIGONUCLEOTIDE; CASPASE 8; GUANINE NUCLEOTIDE BINDING PROTEIN; HEPTANOIC ACID DERIVATIVE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGAND; STAT1 PROTEIN; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR STIMULATING AGENT; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CASPASE; CELL SURFACE RECEPTOR; INTERLEUKIN 1; LEUKOCYTE ANTIGEN; TUMOR NECROSIS FACTOR RECEPTOR;

APOPTOSIS; ARTICLE; BLOOD VESSEL WALL; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; ISCHEMIA; LEUKOCYTE ADHERENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVASCULARIZATION; CELL ADHESION; CELL CULTURE; CYTOLOGY; DRUG EFFECT; IMMUNOLOGY; LEUKOCYTE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

ANTIGENS, CD; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL ADHESION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GTP-BINDING PROTEINS; HEPTANOIC ACIDS; HUMANS; INTERLEUKIN-1; LEUKOCYTES; LIGANDS; NF-KAPPA B; RECEPTOR CROSS-TALK; RECEPTORS, CELL SURFACE; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; SIGNAL TRANSDUCTION; THROMBOXANE A2; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL VEINS;

EID: 0038485645     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210766200     Document Type: Article

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