Single-molecule detection technologies in miniaturized high-throughput screening: Fluorescence intensity distribution analysis

Journal of Biomolecular Screening

Volumn 8, Issue 1, 2003, Pages 19-33

  Haupts, Ulrich ^a,c   Rüdiger, Martin ^a   Ashman, Stephen ^a   Turconi, Sandra ^a,d   Bingham, Ryan ^a   Wharton, Charlotte ^a   Hutchinson, Jonathan ^a   Carey, Charlotte ^a   Moore, Keith J ^a   Pope, Andrew J ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b GLAXOSMITHKLINE   (United States)

^c Direvo Biotech AG   (Germany)

^d Devgen   (Belgium)

Author keywords

Confocal; Fluorescence; Miniaturization; Single molecule; uHTS

Indexed keywords

ALCOHOL DEHYDROGENASE; ALKALINE PHOSPHATASE; CASPASE 3; CATHEPSIN D; CYTOCHROME; CYTOCHROME P450; FLUORESCEIN; GUANOSINE DIPHOSPHATE; ISOTHIOCYANIC ACID; MELANIN CONCENTRATING HORMONE; NEW DRUG; PHOSPHOLIPASE A2; PHOSPHOTRANSFERASE; PHOSPHOTYROSINE; PROTEIN KINASE P60; PROTEIN P21; PROTEINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RESORUFIN DERIVATIVE; RHODAMINE; RIBOSOME RNA; STAUROSPORINE; TETRAMETHYLRHODAMINE; UNCLASSIFIED DRUG; HUMAN PLATELET ANTIGEN 1B; LIGAND; RNA; THROMBOCYTE ANTIGEN;

ANISOTROPY; ARGON LASER; ARTICLE; AUTOFLUORESCENCE; BRIGHTNESS; COMPUTER PROGRAM; CONFOCAL MICROSCOPY; ENZYME ASSAY; FLUORESCENCE; FLUORESCENCE INTENSITY DISTRIBUTION ANALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HELIUM NEON LASER; HIGH THROUGHPUT SCREENING; MASS; MOLECULE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STOICHIOMETRY; METABOLISM;

ALCOHOL DEHYDROGENASE; ALKALINE PHOSPHATASE; ANTIGENS, HUMAN PLATELET; ENDOPEPTIDASES; FLUORESCENCE; LIGANDS; MICROSCOPY, CONFOCAL; RNA;

EID: 0038479634     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057102239669     Document Type: Article

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