The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites

BMC Cell Biology

Volumn 2, Issue , 2001, Pages

  Lutter, Michael ^a   Perkins, Guy A ^b   Wang, Xiaodong ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN; CYTOCHROME C; GLUTAMIC ACID; GLYCINE; MUTANT PROTEIN; PROTEIN BCL 2; PROTEIN BID; BID PROTEIN, MOUSE; CARRIER PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ELECTRON MICROSCOPY; IMMUNOELECTRON MICROSCOPY; IMMUNOGOLD LABELING; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NONHUMAN; OUTER MEMBRANE; POINT MUTATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN TARGETING; REGULATORY MECHANISM; STATISTICAL ANALYSIS; TOMOGRAPHY; WILD TYPE; ANIMAL; CHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INTRACELLULAR MEMBRANE; LIVER MITOCHONDRION; METHODOLOGY; PHYSIOLOGY; THREE DIMENSIONAL IMAGING; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; IMAGING, THREE-DIMENSIONAL; IMMUNOHISTOCHEMISTRY; INTRACELLULAR MEMBRANES; MICE; MICROSCOPY, ELECTRON; MITOCHONDRIA; MITOCHONDRIA, LIVER; PROTO-ONCOGENE PROTEINS C-BCL-2; TOMOGRAPHY;

EID: 18744374204     PISSN: 14712121     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2121-2-22     Document Type: Article

References (33)

1. Vander Heiden MG, Thompson CB: Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis? Nat Cell Biol 1999, 1:E209-216
2. Li H, Zhu H, Xu C, Yuan J: Cleavage of Bid by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998, 94:491-501
3. Luo X, Budihardjo I, Zou H, Slaughter C, Wang X: Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998, 94:481-490
4. Du C, Fang M, Li Y, Li L, Wang X: Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000, 102:33-42
5. Li LY, Luo X, Wang X: Endonuclease G is an apoptotic DNAse when released from mitochondria. Nature 2001, 412:95-99
6. Vander Heiden MG, Chandel NS, Schumacker PT, Thompson CB: Bcl-XL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange. Molecular Cell 1999, 3:159-167
7. Vander Heiden MG, Li XX, Gottlieb E, Hill RB, Thompson CB, Colombini M: Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. J Biol Chem 2001, 276:19414-19419
8. Mootha VK, Wei MC, Buttle KF, Scorrano L, Panoutsakopoulou V, Mannella CA, Korsmeyer SK: A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c. EMBO J 2001, 20:661-671
9. Lutter M, Fang M, Luo X, Nishijima M, Xie X, Wang X: Cardiolipin provides specificity for targeting of tBid to mitochondria. Nature Cell Biol 2000, 2:754-761
10. Ardail D, Privat J, Egret-Charlier M, Levrat C, Lerme F, Louisot P: Mitochondrial Contact Sites. J Biol Chem 1990, 265:18797-18802
11. Perkins G, Frey T: Electron tomography In: Encyclopedia of Molecular Biology. (Edited by Creighton T). New York, John Wiley & Sons 1999796
12. Frey TG, Mannella CA: The internal structure of mitochondria. TIBS 2000, 25:319-324
13. Perkins G, Renken C, Martone M, Young S, Ellisman MH, Frey TG: Electron tomography of neuronal mitochondria : 3-D structure and organization of cristae and membrane contacts. J Struct Biol 1997, 119:260-272
14. Perkins G, Frey T: Recent structural insights into mitochondria obtained by microscopy. Micron 2000, 31:97-111
15. Perkins G, Renken C, Song JY, Young S, Lamont S, Martone M, Lindsey S, Frey TG, Ellisman MH: Electron tomography of large, multicomponent biological structures. J Struct Biol 1997, 120:219-227
16. Boots BN, Getis A: Point Pattern Analysis. Newbury Park, Sage 1988
17. Lehninger AL, Nelson DL, Cox MM: Principles of Biochemistry. New York, Worth Publishers 1993
18. Crompton M: Mitochondrial intermembrane junctional complexes and their role in cell death. J Physiol 2000, 529:11-21
19. Chen JJ, Bertrand H, Yu BP: Inhibition of adenine nucleotide translocator by lipid peroxidation products. Free Radical Biol Medicine 1995, 19:583-590
20. Hoffmann B, Stockl A, Schlame M, Beyer K, Klingenberg M: The reconstituted ADP/ATP carrier activity has an absolute requirement for cardiolipin as shown in cysteine mutants. J Biol Chem 1994, 269:1940-1944
21. Muller M, Moser R, Cheneval D, Carafoli E: Cardiolipin is the membrane receptor for mitochondrial creatine phosphokinase. J Biol Chem 1985, 260:3839-3843
22. Weiss C, Oppliger W, Vergeres G, Demel R, Jeno P, Horst M, De Kruijff B, Schatz G, Azem A: Domain structure and lipid interaction of recombinant yeast Tim 44. Proc Natl Acad Sci USA 1999, 96:8890-8894
23. Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ: Proapoptotic Bax and Bak: A requisite gateway to mitochondrial dysfunction and death. Science 2001, 292:727-730
24. Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB: BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 2001, 15:1481-1486
25. Basanez G, Nechushtan A, Drozhinin O, Chanturiya A, Choe E, Tutt S, Wood KA, Hsu Y, Zimmerberg J, Youle RJ: Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations. Proc Natl Acad Sci USA 1999, 96:5492-5497
26. Kudla G, Montessuit S, Eskes R, Berrier C, Martinou J, Ghazi A, Antonsson B: The destabilization of lipid membranes induced by the c-terminal fragment of caspase-8 cleaved Bid is inhibited by the n-terminal fragment. J Biol Chem 2000, 275:22713-22718
27. Bernardi P, Petronilli V, Di Lisa F, Forte M: A mitochondrial perspective on cell death. Trends Biochem Sci 2001, 26:112-117
28. Doran E, Halestrap AP: Cytochrome c release from isolated liver can occur independently of outer-membrane rupture: Possible role of contact sites. Biochem J 2000, 348:343-350
29. Von Ahsen O, Renken C, Perkins G, Kluck RM, Bossy-Wetzel E, Newmeyer DD: Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release. J Cell Biol 2000, 150:1027-1036
30. Vander Heiden MG, Chandel NS, Williamson EK, Schumacher PT, Thompson CB: Bcl-XL regulates the membrane potential and volume homeostasis of mitochondria. Cell 1997, 91:627-637
31. Cai J, Jones DP: Mitochondrial generation triggered by cytochrome c loss. J Biol Chem 1998, 273:11401-11404
32. Shoop RD, Martone ME, Yamada N, Ellisman ME, Berg DK: Neuronal acetylcholine receptors with α7 subunits are concentrated on somatic spines for synaptic signaling in embryonic chick ciliary ganglia. J Neurosci 1999, 19:692-704
33. Hackenbrock CR: Chemical and physical fixation of isolated mitochondria in low-energy and high-energy states. Proc Natl Acad Sci USA 1968, 61:598-605