-
1
-
-
0034282916
-
Regulation of the liver fatty acid-binding protein gene by hepatocyte nuclear factor 1α (HNF-1α). Alterations in fatty acid homeostasis in HNF-1α-deficient mice
-
Akiyama TE, Ward JM, and Gonzalez FJ. Regulation of the liver fatty acid-binding protein gene by hepatocyte nuclear factor 1α (HNF-1α). Alterations in fatty acid homeostasis in HNF-1α-deficient mice. J Biol Chem 275: 27117-27122, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 27117-27122
-
-
Akiyama, T.E.1
Ward, J.M.2
Gonzalez, F.J.3
-
2
-
-
0027495280
-
Interplay of the liver-enriched transacting factors, DBP and HNF-1, in the transactivation of human IGFBP-1 promoter
-
Babajko S and Groyer A. Interplay of the liver-enriched transacting factors, DBP and HNF-1, in the transactivation of human IGFBP-1 promoter. Biochem Biophys Res Commun 196: 480-486, 1993.
-
(1993)
Biochem Biophys Res Commun
, vol.196
, pp. 480-486
-
-
Babajko, S.1
Groyer, A.2
-
3
-
-
0021956354
-
Regulation of the biosynthesis of two distinct fatty acid-binding proteins in rat liver and intestine. Influences of sex difference and of clofibrate
-
Bass NM, Manning JA, Ockner RK, Gordon JI, Seetharam S, and Alpers DH. Regulation of the biosynthesis of two distinct fatty acid-binding proteins in rat liver and intestine. Influences of sex difference and of clofibrate. J Biol Chem 260: 1432-1436, 1985.
-
(1985)
J Biol Chem
, vol.260
, pp. 1432-1436
-
-
Bass, N.M.1
Manning, J.A.2
Ockner, R.K.3
Gordon, J.I.4
Seetharam, S.5
Alpers, D.H.6
-
4
-
-
0028905545
-
Regulation of J6 gene expression by transcription factor GATA-4
-
Bielinska M and Wilson DB. Regulation of J6 gene expression by transcription factor GATA-4. Biochem J 307: 183-189, 1995.
-
(1995)
Biochem J
, vol.307
, pp. 183-189
-
-
Bielinska, M.1
Wilson, D.B.2
-
5
-
-
0037200071
-
Hepatocyte nuclear factor-1α, GATA-4, and caudal related homeodomain protein Cdx2 interact functiona]]y functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene
-
Boudreau F, Rings EHHM, van Wering HM, Kim RK, Swain GP, Krasinski SD, Moffett J, Grand RJ, Suh ER, and Traber PG. Hepatocyte nuclear factor-1α, GATA-4, and caudal related homeodomain protein Cdx2 interact functiona]]y functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene. J Biol Chem 277: 31909-31917, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 31909-31917
-
-
Boudreau, F.1
Rings, E.H.H.M.2
Van Wering, H.M.3
Kim, R.K.4
Swain, G.P.5
Krasinski, S.D.6
Moffett, J.7
Grand, R.J.8
Suh, E.R.9
Traber, P.G.10
-
6
-
-
0035943624
-
Sucrase-isomaltase gene transcription requires the hepatocyte nuclear factor-1 (HNF-1) regulatory element and is regulated by the ratio of HNF-1α to HNF-1β
-
Boudreau F, Zhu Y, and Traber PG. Sucrase-isomaltase gene transcription requires the hepatocyte nuclear factor-1 (HNF-1) regulatory element and is regulated by the ratio of HNF-1α to HNF-1β. J Biol Chem 276: 32122-32128, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 32122-32128
-
-
Boudreau, F.1
Zhu, Y.2
Traber, P.G.3
-
7
-
-
10244249309
-
Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12
-
Byrne NM, Sturis J, Menzel S, Yamagata K, Fajans SS, Dronsfield MJ, Bain SC, Hattersley AT, Velho G, Froguel P, Bell GI, and Polonsky KS. Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12. Diabetes 45: 1503-1510, 1996.
-
(1996)
Diabetes
, vol.45
, pp. 1503-1510
-
-
Byrne, N.M.1
Sturis, J.2
Menzel, S.3
Yamagata, K.4
Fajans, S.S.5
Dronsfield, M.J.6
Bain, S.C.7
Hattersley, A.T.8
Velho, G.9
Froguel, P.10
Bell, G.I.11
Polonsky, K.S.12
-
8
-
-
0032884694
-
Repression and activation of transcription of phosphoenolpyruvate carboxykinase gene during liver development
-
Cassuto H, Aran A, Cohen H, Eisenberger CL, and Reshef L. Repression and activation of transcription of phosphoenolpyruvate carboxykinase gene during liver development. FEBS Lett 457: 441-444, 1999.
-
(1999)
FEBS Lett
, vol.457
, pp. 441-444
-
-
Cassuto, H.1
Aran, A.2
Cohen, H.3
Eisenberger, C.L.4
Reshef, L.5
-
9
-
-
0034674711
-
Identification of transacting factors responsible for the tissue-specific expression of human glucose transporter type 2 isoform gene. Cooperative role of hepatocyte nuclear factors 1α and 3β
-
Cha JY, Kim H, Kim KS, Hur MW, and Ahn Y. Identification of transacting factors responsible for the tissue-specific expression of human glucose transporter type 2 isoform gene. Cooperative role of hepatocyte nuclear factors 1α and 3β. J Biol Chem 275: 18358-18365, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 18358-18365
-
-
Cha, J.Y.1
Kim, H.2
Kim, K.S.3
Hur, M.W.4
Ahn, Y.5
-
10
-
-
0026032236
-
Temporal and spatial patterns of transgene expression in aging adult mice provide insights about the origins, organization, and differentiation of the intestinal epithelium
-
Cohn SM, Roth KA, Birkenmeier EH, and Gordon JI. Temporal and spatial patterns of transgene expression in aging adult mice provide insights about the origins, organization, and differentiation of the intestinal epithelium. Proc Natl Acad Sci USA 88: 1034-1038, 1991.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 1034-1038
-
-
Cohn, S.M.1
Roth, K.A.2
Birkenmeier, E.H.3
Gordon, J.I.4
-
12
-
-
0028892856
-
Transcription factor and liver-specific mRNA expression in facultative epithelial progenitor cells of liver and pancreas
-
Dabeva MD, Hurston E, and Sharitz DA. Transcription factor and liver-specific mRNA expression in facultative epithelial progenitor cells of liver and pancreas. Am J Pathol 147: 1633-1648, 1995.
-
(1995)
Am J Pathol
, vol.147
, pp. 1633-1648
-
-
Dabeva, M.D.1
Hurston, E.2
Sharitz, D.A.3
-
13
-
-
0025853775
-
LFB3, a heterodimerforming homeoprotein of the LFB1 family, is expressed in specialized epithelia
-
De Simone V, De Magistris L, Lazzaro D, Gerstner J, Monaci P, Nicosia A, and Cortese R. LFB3, a heterodimerforming homeoprotein of the LFB1 family, is expressed in specialized epithelia. EMBO J 10: 1435-1443, 1991.
-
(1991)
EMBO J
, vol.10
, pp. 1435-1443
-
-
De Simone, V.1
De Magistris, L.2
Lazzaro, D.3
Gerstner, J.4
Monaci, P.5
Nicosia, A.6
Cortese, R.7
-
14
-
-
0031431903
-
Liver-enriched transcription factors, HNF-1, HNF-3, and C/EBP, are major contributors to the strong activity of the chicken CYP 2H1 promoter in chick embryo hepatocytes
-
Dogra SC and May BK. Liver-enriched transcription factors, HNF-1, HNF-3, and C/EBP, are major contributors to the strong activity of the chicken CYP2H1 promoter in chick embryo hepatocytes. DNA Cell Biol 16: 1407-1418, 1997.
-
(1997)
DNA Cell Biol
, vol.16
, pp. 1407-1418
-
-
Dogra, S.C.1
May, B.K.2
-
15
-
-
0030042979
-
Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes
-
Drewes T, Senkel S, Holewa B, and Ryffel GU. Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes. Mol Cell Biol 16: 925-931, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 925-931
-
-
Drewes, T.1
Senkel, S.2
Holewa, B.3
Ryffel, G.U.4
-
16
-
-
0032584567
-
Regulation of a transcription factor network required for differentiation and metabolism
-
Duncan SA, Navas MA, Dufort D, Rossant J, and Stoffel M. Regulation of a transcription factor network required for differentiation and metabolism. Science 281: 692-695, 1998.
-
(1998)
Science
, vol.281
, pp. 692-695
-
-
Duncan, S.A.1
Navas, M.A.2
Dufort, D.3
Rossant, J.4
Stoffel, M.5
-
17
-
-
0033752712
-
Hepatocyte nuclear factor 1 alpha (HNF-1α) mutations in maturity-onset diabetes of the young
-
Ellard S. Hepatocyte nuclear factor 1 alpha (HNF-1α) mutations in maturity-onset diabetes of the young. Hum Mutat 16: 377-385, 2000.
-
(2000)
Hum Mutat
, vol.16
, pp. 377-385
-
-
Ellard, S.1
-
18
-
-
0035122282
-
β-cell genes and diabetes: Molecular and clinical characterization of mutations in transcription factors
-
Frayling TM, Evans JC, Bulman MP, Pearson E, Allen L, Owen K, Bingham C, Hannemann M, Shepherd M, Ellard S, and Hattersley AT. β-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors. Diabetes 50: S94-S100, 2001.
-
(2001)
Diabetes
, vol.50
-
-
Frayling, T.M.1
Evans, J.C.2
Bulman, M.P.3
Pearson, E.4
Allen, L.5
Owen, K.6
Bingham, C.7
Hannemann, M.8
Shepherd, M.9
Ellard, S.10
Hattersley, A.T.11
-
19
-
-
0033058487
-
Molecular genetics of maturity-onset diabetes of the young
-
Froguel P and Velho G. Molecular genetics of maturity-onset diabetes of the young. Trends Endocrinol Metab 10: 142-146, 1999.
-
(1999)
Trends Endocrinol Metab
, vol.10
, pp. 142-146
-
-
Froguel, P.1
Velho, G.2
-
20
-
-
0034796563
-
Regulatory mechanisms controlling human hepatocyte nuclear factor 4α gene expression
-
Hatzis P and Talianidis I. Regulatory mechanisms controlling human hepatocyte nuclear factor 4α gene expression. Mol Cell Biol 21: 7320-7330, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7320-7330
-
-
Hatzis, P.1
Talianidis, I.2
-
21
-
-
0031860393
-
Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL
-
Heinemeyer T, Wingender E, Reuter I, Hermjakob H, Kel AE, Kel OV, Ignatieva EV, Ananko EA, Podkolodnaya OA, Kolpakov FA, Podkolodny NL, and Kolchanov NA. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Res 26: 362-367, 1998.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 362-367
-
-
Heinemeyer, T.1
Wingender, E.2
Reuter, I.3
Hermjakob, H.4
Kel, A.E.5
Kel, O.V.6
Ignatieva, E.V.7
Ananko, E.A.8
Podkolodnaya, O.A.9
Kolpakov, F.A.10
Podkolodny, N.L.11
Kolchanov, N.A.12
-
22
-
-
0030783259
-
Hepatocyte nuclear factor-1α regulates transcription of the guanylin gene
-
Hochman JA, Sciaky D, Whitaker TL, Hawkins JA, and Cohen MB. Hepatocyte nuclear factor-1α regulates transcription of the guanylin gene. Am J Physiol Gastrointest Liver Physiol 273: G833-G841, 1997.
-
(1997)
Am J Physiol Gastrointest Liver Physiol
, vol.273
-
-
Hochman, J.A.1
Sciaky, D.2
Whitaker, T.L.3
Hawkins, J.A.4
Cohen, M.B.5
-
23
-
-
33746471838
-
1-antitrypsin gene expression in human intestinal epithelial cell line Caco-2 by HNF-1α and HNF-4
-
1-antitrypsin gene expression in human intestinal epithelial cell line Caco-2 by HNF-1α and HNF-4. Am J Physiol Gastrointest Liver Physiol 276: G1181-G1194, 1999.
-
(1999)
Am J Physiol Gastrointest Liver Physiol
, vol.276
-
-
Hu, C.1
Perlmutter, D.H.2
-
24
-
-
0034057412
-
Octamer transcription factor-1 enhances hepatic nuclear factor-1α-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter
-
Ishii Y, Hansen AJ, and Mackenzie PI. Octamer transcription factor-1 enhances hepatic nuclear factor-1α-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter. Mol Pharmacol 57: 940-947, 2000.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 940-947
-
-
Ishii, Y.1
Hansen, A.J.2
Mackenzie, P.I.3
-
25
-
-
15444341853
-
Mutations in the hepatocyte nuclear factor-1α/MODY3 gene in Japanese subjects with early- and late-onset NIDDM
-
Iwasaki N, Oda N, Ogata M, Hara M, Hinokio Y, Oda Y, Yamagata K, Kanematsu S, Ohgawara H, Omori Y, and Bell GI. Mutations in the hepatocyte nuclear factor-1α/MODY3 gene in Japanese subjects with early- and late-onset NIDDM. Diabetes 46: 1504-1508, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1504-1508
-
-
Iwasaki, N.1
Oda, N.2
Ogata, M.3
Hara, M.4
Hinokio, Y.5
Oda, Y.6
Yamagata, K.7
Kanematsu, S.8
Ohgawara, H.9
Omori, Y.10
Bell, G.I.11
-
26
-
-
0031767978
-
Liver and kidney function in Japanese patients with maturity-onset diabetes of the young
-
Iwasaki N, Ogata M, Tomonaga O, Kuroki H, Kasahara T, Yano N, and Iwamoto Y. Liver and kidney function in Japanese patients with maturity-onset diabetes of the young. Diabetes Care 21: 2144-2148, 1998.
-
(1998)
Diabetes Care
, vol.21
, pp. 2144-2148
-
-
Iwasaki, N.1
Ogata, M.2
Tomonaga, O.3
Kuroki, H.4
Kasahara, T.5
Yano, N.6
Iwamoto, Y.7
-
28
-
-
0027752776
-
An indirect negative autoregulatory mechanism involved in hepatocyte nuclear factor-1 gene expression
-
Kritis AA, Ktistaki E, Barda D, Zannis VI, and Talianidis I. An indirect negative autoregulatory mechanism involved in hepatocyte nuclear factor-1 gene expression. Nucleic Acids Res 21: 5882-5889, 1993.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 5882-5889
-
-
Kritis, A.A.1
Ktistaki, E.2
Barda, D.3
Zannis, V.I.4
Talianidis, I.5
-
29
-
-
0030848766
-
Modulation of hepatic gene expression by hepatocyte nuclear factor 1
-
Ktistaki E and Talianidis I. Modulation of hepatic gene expression by hepatocyte nuclear factor 1. Science 277: 109-112, 1997.
-
(1997)
Science
, vol.277
, pp. 109-112
-
-
Ktistaki, E.1
Talianidis, I.2
-
30
-
-
0030027263
-
Members of the caudal family of homeodomain proteins repress transcription from the human apolipoprotein B promoter in intestinal cells
-
Lee SY, Nagy BP, Brooks AR, Wang DM, Paulweber B, and Levy-Wilson B. Members of the caudal family of homeodomain proteins repress transcription from the human apolipoprotein B promoter in intestinal cells. J Biol Chem 271: 707-718, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 707-718
-
-
Lee, S.Y.1
Nagy, B.P.2
Brooks, A.R.3
Wang, D.M.4
Paulweber, B.5
Levy-Wilson, B.6
-
31
-
-
0031944313
-
Laron dwarfism and non-insulin-dependent diabetes mellitus in the HNF-1α knockout mouse
-
Lee YH, Sauer B, and Gonzalez FJ. Laron dwarfism and non-insulin-dependent diabetes mellitus in the HNF-1α knockout mouse. Mol Cell Biol 18: 3059-3068, 1998.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3059-3068
-
-
Lee, Y.H.1
Sauer, B.2
Gonzalez, F.J.3
-
32
-
-
0028086443
-
Transactivation of the rat CYP2C13 gene promoter involves HNF-1, HNF-3, and members of the orphan receptor subfamily
-
Legraverend C, Eguchi H, Strom A, Lahuna O, Mode A, Tollet P, Westin S, and Gustafsson JA. Transactivation of the rat CYP2C13 gene promoter involves HNF-1, HNF-3, and members of the orphan receptor subfamily. Biochemistry 33: 9889-9897, 1994.
-
(1994)
Biochemistry
, vol.33
, pp. 9889-9897
-
-
Legraverend, C.1
Eguchi, H.2
Strom, A.3
Lahuna, O.4
Mode, A.5
Tollet, P.6
Westin, S.7
Gustafsson, J.A.8
-
33
-
-
0032491430
-
Retinoic acid mediates down-regulation of the alpha-fetoprotein gene through decreased expression of hepatocyte nuclear factors
-
Magee TR, Cai Y, El-Houseini ME, Locker J, and Wan YJ. Retinoic acid mediates down-regulation of the alpha-fetoprotein gene through decreased expression of hepatocyte nuclear factors. J Biol Chem 273: 30024-30032, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 30024-30032
-
-
Magee, T.R.1
Cai, Y.2
El-Houseini, M.E.3
Locker, J.4
Wan, Y.J.5
-
34
-
-
0025892211
-
HNF-1α and HNF-1β (vHNF-1) share dimerization and homeodomains, but not activation domains, and form heterodimers in vitro
-
Mendel DB, Hansen LP, Graves MK, Conley PB, and Crabtree GR. HNF-1α and HNF-1β (vHNF-1) share dimerization and homeodomains, but not activation domains, and form heterodimers in vitro. Genes Dev 5: 1042-1056, 1991.
-
(1991)
Genes Dev
, vol.5
, pp. 1042-1056
-
-
Mendel, D.B.1
Hansen, L.P.2
Graves, M.K.3
Conley, P.B.4
Crabtree, G.R.5
-
35
-
-
0031684710
-
A low renal threshold for glucose in diabetic patients with a mutation in the hepatocyte nuclear factor-1α (HNF-1α) gene
-
Menzel R, Kaisaki PJ, Rjasanowski I, Heinke P, Kerner W, and Menzel S. A low renal threshold for glucose in diabetic patients with a mutation in the hepatocyte nuclear factor-1α (HNF-1α) gene. Diabet Med 15: 816-820, 1998.
-
(1998)
Diabet Med
, vol.15
, pp. 816-820
-
-
Menzel, R.1
Kaisaki, P.J.2
Rjasanowski, I.3
Heinke, P.4
Kerner, W.5
Menzel, S.6
-
37
-
-
0032557437
-
The HOXC11 homeodomain protein interacts with the lactase-phlorizin hydrolase promoter and stimulates HNF-1α-dependent transcription
-
Mitchelmore C, Troelsen JT, Sjostrom H, and Noren O . The HOXC11 homeodomain protein interacts with the lactase-phlorizin hydrolase promoter and stimulates HNF-1α-dependent transcription. J Biol Chem 273: 13297-13306, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 13297-13306
-
-
Mitchelmore, C.1
Troelsen, J.T.2
Sjostrom, H.3
Noren, O.4
-
38
-
-
0034163801
-
Interaction between the homeodomain proteins Cdx2 and HNF-1α mediates expression of the lactase-phlorizin hydrolase gene
-
Mitchelmore C, Troelsen JT, Spodsberg N, Sjostrom H, and Noren O. Interaction between the homeodomain proteins Cdx2 and HNF-1α mediates expression of the lactase-phlorizin hydrolase gene. Biochem J 346: 529-535, 2000.
-
(2000)
Biochem J
, vol.346
, pp. 529-535
-
-
Mitchelmore, C.1
Troelsen, J.T.2
Spodsberg, N.3
Sjostrom, H.4
Noren, O.5
-
39
-
-
0021996148
-
The first intron of the human growth hormone gene contains a binding site for glucocorticoid receptor
-
Moore DD, Marks AR, Buckley DI, Kapler G, Payvar F, and Goodman HM. The first intron of the human growth hormone gene contains a binding site for glucocorticoid receptor. Proc Natl Acad Sci USA 82: 699-702, 1985.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 699-702
-
-
Moore, D.D.1
Marks, A.R.2
Buckley, D.I.3
Kapler, G.4
Payvar, F.5
Goodman, H.M.6
-
40
-
-
0034809513
-
Maturity-onset diabetes of the young: From clinical description to molecular genetic characterization
-
Owen K and Hattersley AT. Maturity-onset diabetes of the young: from clinical description to molecular genetic characterization. Best Practice Res Clin Endocrinol Metab 15: 309-323, 2001.
-
(2001)
Best Practice Res Clin Endocrinol Metab
, vol.15
, pp. 309-323
-
-
Owen, K.1
Hattersley, A.T.2
-
41
-
-
0026672433
-
Hepatocyte nuclear factor 3β contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein
-
Pani L, Overdier DG, Porcella A, Qian X, Lai E, and Costa RH. Hepatocyte nuclear factor 3β contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein. Mol Cell Biol 12: 3723-3732, 1992.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3723-3732
-
-
Pani, L.1
Overdier, D.G.2
Porcella, A.3
Qian, X.4
Lai, E.5
Costa, R.H.6
-
42
-
-
0035918294
-
The mouse fetoprotein transcription factor (FTF) gene promoter is regulated by three GATA elements with tandem E box and Nkx motifs, and FTF in turn activates the HNF-3β, HNF-4α, and HNF-1α gene promoters
-
Pare JF, Roy S, Galarneau L, and Belanger L. The mouse fetoprotein transcription factor (FTF) gene promoter is regulated by three GATA elements with tandem E box and Nkx motifs, and FTF in turn activates the HNF-3β, HNF-4α, and HNF-1α gene promoters. J Biol Chem 276: 13136-13144, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 13136-13144
-
-
Pare, J.F.1
Roy, S.2
Galarneau, L.3
Belanger, L.4
-
43
-
-
0030031453
-
Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome
-
Pontoglio M, Barra J, Hadchouel M, Doyen A, Kress C, Bach JP, Babinet C, and Yaniv M. Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome. Cell 84: 575-585, 1996.
-
(1996)
Cell
, vol.84
, pp. 575-585
-
-
Pontoglio, M.1
Barra, J.2
Hadchouel, M.3
Doyen, A.4
Kress, C.5
Bach, J.P.6
Babinet, C.7
Yaniv, M.8
-
44
-
-
18144452590
-
Defective insulin secretion in hepatocyte nuclear factor 1α-deficient mice
-
Pontoglio M, Sreenan S, Roe M, Pugh W, Ostrega D, Doyen A, Pick AJ, Baldwin A, Velho G, Froguel P, Levisetti M, Bonner-Weir S, Bell GI, Yaniv M, and Polonsky KS. Defective insulin secretion in hepatocyte nuclear factor 1α-deficient mice. J Clin Invest 101: 2215-2222, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 2215-2222
-
-
Pontoglio, M.1
Sreenan, S.2
Roe, M.3
Pugh, W.4
Ostrega, D.5
Doyen, A.6
Pick, A.J.7
Baldwin, A.8
Velho, G.9
Froguel, P.10
Levisetti, M.11
Bonner-Weir, S.12
Bell, G.I.13
Yaniv, M.14
Polonsky, K.S.15
-
45
-
-
0025775278
-
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
-
Rey-Campos J, Chouard T, Yaniv M, and Cereghini S. vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1. EMBO J 10: 1445-1457, 1991.
-
(1991)
EMBO J
, vol.10
, pp. 1445-1457
-
-
Rey-Campos, J.1
Chouard, T.2
Yaniv, M.3
Cereghini, S.4
-
46
-
-
0034892164
-
Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: Functional and pathological consequences
-
Ryffel GU. Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences. J Mol Endocrinol 27: 11-29, 2001.
-
(2001)
J Mol Endocrinol
, vol.27
, pp. 11-29
-
-
Ryffel, G.U.1
-
47
-
-
0033621427
-
Inducible gene knockouts in the small intestinal and colonic epithelium
-
Saam JR and Gordon JI. Inducible gene knockouts in the small intestinal and colonic epithelium. J Biol Chem 274: 38071-38082, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 38071-38082
-
-
Saam, J.R.1
Gordon, J.I.2
-
49
-
-
0035092762
-
Genetic testing in maturity onset diabetes of the young (MODY): A new challenge for the diabetic clinic
-
Shepherd M, Sparkes A, and Hattersley A. Genetic testing in maturity onset diabetes of the young (MODY): A new challenge for the diabetic clinic. Pract Diab Int 18: 16-21, 2001.
-
(2001)
Pract Diab Int
, vol.18
, pp. 16-21
-
-
Shepherd, M.1
Sparkes, A.2
Hattersley, A.3
-
50
-
-
0035072875
-
Hepatocyte nuclear factor-1α is an essential regulator of bile acid and plasma cholesterol metabolism
-
Shih DQ, Bussen M, Sehayek E, Ananthanarayanan M, Shneider BL, Suchy FJ, Shefer S, Bollileni JS, Gonzalez FJ, Breslow JL, and Stoffel M. Hepatocyte nuclear factor-1α is an essential regulator of bile acid and plasma cholesterol metabolism. Nat Genet 27: 375-382, 2001.
-
(2001)
Nat Genet
, vol.27
, pp. 375-382
-
-
Shih, D.Q.1
Bussen, M.2
Sehayek, E.3
Ananthanarayanan, M.4
Shneider, B.L.5
Suchy, F.J.6
Shefer, S.7
Bollileni, J.S.8
Gonzalez, F.J.9
Breslow, J.L.10
Stoffel, M.11
-
51
-
-
0030929853
-
Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice
-
Simon TC, Cho A, Tso P, and Gordon JI. Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice. J Biol Chem 272: 10652-10663, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 10652-10663
-
-
Simon, T.C.1
Cho, A.2
Tso, P.3
Gordon, J.I.4
-
52
-
-
0027185340
-
Use of transgenic mice to map cis-acting elements in the liver fatty acid-binding protein gene (Fabpl) that regulate its cell lineage-specific, differentiation-dependent, and spatial patterns of expression in the gut epithelium and in the liver acinus
-
Simon TC, Roth KA, and Gordon JI. Use of transgenic mice to map cis-acting elements in the liver fatty acid-binding protein gene (Fabpl) that regulate its cell lineage-specific, differentiation-dependent, and spatial patterns of expression in the gut epithelium and in the liver acinus. J Biol Chem 268: 18345-18358, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 18345-18358
-
-
Simon, T.C.1
Roth, K.A.2
Gordon, J.I.3
-
53
-
-
0025690311
-
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
-
Sladek FM, Zhong WM, Lai E, and Darnell JE Jr. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev 4: 2353-2365, 1990.
-
(1990)
Genes Dev
, vol.4
, pp. 2353-2365
-
-
Sladek, F.M.1
Zhong, W.M.2
Lai, E.3
Darnell J.E., Jr.4
-
54
-
-
0032561358
-
Vitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1α and 1β
-
Song YH, Ray K, Liebhaber SA, and Cooke NE. Vitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1α and 1β. J Biol Chem 273: 28408-28418, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 28408-28418
-
-
Song, Y.H.1
Ray, K.2
Liebhaber, S.A.3
Cooke, N.E.4
-
55
-
-
0032941790
-
Functional study of the E276Q mutant hepatocyte nuclear factor-4α found in type 1 maturity-onset diabetes of the young: Impaired synergy with chicken ovalbumin upstream promoter transcription factor II on the hepatocyte nuclear factor-1 promoter
-
Suaud L, Hemimou Y, Formstecher P, and Laine B. Functional study of the E276Q mutant hepatocyte nuclear factor-4α found in type 1 maturity-onset diabetes of the young: impaired synergy with chicken ovalbumin upstream promoter transcription factor II on the hepatocyte nuclear factor-1 promoter. Diabetes 48: 1162-1167, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 1162-1167
-
-
Suaud, L.1
Hemimou, Y.2
Formstecher, P.3
Laine, B.4
-
56
-
-
0024097375
-
Mechanisms underlying generation of gradients in gene expression within the intestine: An analysis using transgenic mice containing fatty acid binding protein-human growth hormone fusion genes
-
Sweetser DA, Birkenmeier EH, Hoppe PC, McKeel DW, and Gordon JI. Mechanisms underlying generation of gradients in gene expression within the intestine: an analysis using transgenic mice containing fatty acid binding protein-human growth hormone fusion genes. Genes Dev 2: 1318-1332, 1988.
-
(1988)
Genes Dev
, vol.2
, pp. 1318-1332
-
-
Sweetser, D.A.1
Birkenmeier, E.H.2
Hoppe, P.C.3
McKeel, D.W.4
Gordon, J.I.5
-
57
-
-
0031410425
-
Comparison of intestinal phospholipase A/lysophospholipase and sucrase-isomaltase genes suggest a common structure for enterocyte-specific promoters
-
Taylor JK, Boll W, Levy T, Suh E, Siang S, Mantei N, and Traber PG. Comparison of intestinal phospholipase A/lysophospholipase and sucrase-isomaltase genes suggest a common structure for enterocyte-specific promoters. DNA Cell Biol 16: 1419-1428, 1997.
-
(1997)
DNA Cell Biol
, vol.16
, pp. 1419-1428
-
-
Taylor, J.K.1
Boll, W.2
Levy, T.3
Suh, E.4
Siang, S.5
Mantei, N.6
Traber, P.G.7
-
58
-
-
0024841330
-
Use of transgenic mice to study the routing of secretory proteins in intestinal epithelial cells: Analysis of human growth hormone compartmentalization as a function of cell type and differentiation
-
Trahair JF, Neutra MR, and Gordon JI. Use of transgenic mice to study the routing of secretory proteins in intestinal epithelial cells: analysis of human growth hormone compartmentalization as a function of cell type and differentiation. J Cell Biol 109: 3231-3242, 1989.
-
(1989)
J Cell Biol
, vol.109
, pp. 3231-3242
-
-
Trahair, J.F.1
Neutra, M.R.2
Gordon, J.I.3
-
59
-
-
18344376912
-
HNF-1α G319S, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an Oji-Cree community
-
Triggs-Raine BL, Kirkpatrick RD, Kelly SL, Norquay LD, Cattini PA, Yamagata K, Hanley AJG, Zinman B, Harris SB, Barrett PH, and Hegele RA. HNF-1α G319S, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an Oji-Cree community. Proc Natl Acad Sci USA 99: 4614-4619, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4614-4619
-
-
Triggs-Raine, B.L.1
Kirkpatrick, R.D.2
Kelly, S.L.3
Norquay, L.D.4
Cattini, P.A.5
Yamagata, K.6
Hanley, A.J.G.7
Zinman, B.8
Harris, S.B.9
Barrett, P.H.10
Hegele, R.A.11
-
60
-
-
0026928723
-
HNF1, a homeoprotein member of the hepatic transcription regulatory network
-
Tronche F and Yaniv M. HNF1, a homeoprotein member of the hepatic transcription regulatory network. Bioessays 14: 579-587, 1992.
-
(1992)
Bioessays
, vol.14
, pp. 579-587
-
-
Tronche, F.1
Yaniv, M.2
-
61
-
-
0030953245
-
Synergistic transactivation of HNF-1α, HNF-3, and NF-I contributes to the activation of the liver-specific protein C gene
-
Tsay W, Lee YM, Lee SC, Shen MC, and Chen PJ. Synergistic transactivation of HNF-1α, HNF-3, and NF-I contributes to the activation of the liver-specific protein C gene. DNA Cell Biol 16: 569-577, 1997.
-
(1997)
DNA Cell Biol
, vol.16
, pp. 569-577
-
-
Tsay, W.1
Lee, Y.M.2
Lee, S.C.3
Shen, M.C.4
Chen, P.J.5
-
62
-
-
0037008768
-
Physical interaction between GATA-5 and HNF-1α results in synergistic activation of the human lactase-phlorizin hydrolase promoter
-
Van Wering H, Huibregtse I, van der Zwan S, de Bie M, Dowling L, Grand R, and Krasinski S. Physical interaction between GATA-5 and HNF-1α results in synergistic activation of the human lactase-phlorizin hydrolase promoter. J Biol Chem 277: 27659-27667, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 27659-27667
-
-
Van Wering, H.1
Huibregtse, I.2
Van der Zwan, S.3
De Bie, M.4
Dowling, L.5
Grand, R.6
Krasinski, S.7
-
63
-
-
0033544962
-
Anatomy of a homeoprotein revealed by the analysis of human MODY3 mutations
-
Vaxillaire M, Abderrahmani A, Boutin P, Bailleul B, Froguel P, Yaniv M, and Pontoglio M. Anatomy of a homeoprotein revealed by the analysis of human MODY3 mutations. J Biol Chem 274: 35639-35646, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 35639-35646
-
-
Vaxillaire, M.1
Abderrahmani, A.2
Boutin, P.3
Bailleul, B.4
Froguel, P.5
Yaniv, M.6
Pontoglio, M.7
-
64
-
-
8244219694
-
Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3)
-
Vaxillaire M, Rouard M, Yamagata K, Oda N, Kaisaki PJ, Boriraj W, Chevre JC, Boccio V, Cox RD, Lathrop GM, Dussoix P, Philippe J, Timsit J, Charpentier G, Velho G, Bell GI, and Froguel P. Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3). Hum Mol Genet 6: 583-586, 1997.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 583-586
-
-
Vaxillaire, M.1
Rouard, M.2
Yamagata, K.3
Oda, N.4
Kaisaki, P.J.5
Boriraj, W.6
Chevre, J.C.7
Boccio, V.8
Cox, R.D.9
Lathrop, G.M.10
Dussoix, P.11
Philippe, J.12
Timsit, J.13
Charpentier, G.14
Velho, G.15
Bell, G.I.16
Froguel, P.17
-
65
-
-
0036008552
-
Exploring the etiology of haploinsufficiency
-
Veitia RA. Exploring the etiology of haploinsufficiency. Bioessays 24: 175-184, 2002.
-
(2002)
Bioessays
, vol.24
, pp. 175-184
-
-
Veitia, R.A.1
-
66
-
-
0030891555
-
Maturity-onset diabetes of the young (MODY), MODY genes and non-insulin-dependent diabetes mellitus
-
Velho G and Froguel P. Maturity-onset diabetes of the young (MODY), MODY genes and non-insulin-dependent diabetes mellitus. Diabetes Metab 23, Suppl 2: 34-37, 1997.
-
(1997)
Diabetes Metab
, vol.23
, Issue.SUPPL. 2
, pp. 34-37
-
-
Velho, G.1
Froguel, P.2
-
67
-
-
0028180450
-
Hepatocyte nuclear factor-1α (HNF-1α) and HNF-1β regulate transcription via two elements in an intestine-specific promoter
-
Wu GD, Chen L, Forslund K, and Traber PG. Hepatocyte nuclear factor-1α (HNF-1α) and HNF-1β regulate transcription via two elements in an intestine-specific promoter. J Biol Chem 269: 17080-17085, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 17080-17085
-
-
Wu, G.D.1
Chen, L.2
Forslund, K.3
Traber, P.G.4
-
68
-
-
0028012070
-
The transcription factor HNF1 acts with C/EBP alpha to synergistically activate the human albumin promoter through a novel domain
-
Wu KJ, Wilson DR, Shih C, and Darlington GJ. The transcription factor HNF1 acts with C/EBP alpha to synergistically activate the human albumin promoter through a novel domain. J Biol Chem 269: 1177-1182, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 1177-1182
-
-
Wu, K.J.1
Wilson, D.R.2
Shih, C.3
Darlington, G.J.4
-
69
-
-
0028036672
-
Transcriptional regulation of the phosphoenolpyruvate carboxykinase gene by cooperation between hepatic nuclear factors
-
Yanuka-Kashles O, Cohen H, Trus M, Aran A, Benvenisty N, and Reshef L. Transcriptional regulation of the phosphoenolpyruvate carboxykinase gene by cooperation between hepatic nuclear factors. Mol Cell Biol 14: 7124-7133, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7124-7133
-
-
Yanuka-Kashles, O.1
Cohen, H.2
Trus, M.3
Aran, A.4
Benvenisty, N.5
Reshef, L.6
-
70
-
-
0033135570
-
Developmental competence of the gut endoderm: Genetic potentiation by GATA and HNF3/fork head proteins
-
Zaret K. Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins. Dev Biol 209: 1-10, 1999.
-
(1999)
Dev Biol
, vol.209
, pp. 1-10
-
-
Zaret, K.1
|