β-cell genes and diabetes: Molecular and clinical characterization of mutations in transcription factors

Diabetes

Volumn 50, Issue SUPPL. 1, 2001, Pages

  Frayling, Timothy M ^a,b   Evans, Julie C ^a   Bulman, Michael P ^a   Pearson, Ewan ^a   Allen, Lisa ^a   Owen, Katharine ^a   Bingham, Coralie ^a   Hannemann, Michael ^a   Shepherd, Maggie ^a   Ellard, Sian ^a   Hattersley, Andrew T ^a  

^a UNIVERSITY OF EXETER   (United Kingdom)

^b School of Postgraduate Medicine and Health Sciences   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE; NUCLEAR FACTOR I; TRANSCRIPTION FACTOR;

ADOLESCENT; ADULT; AMINO ACID SUBSTITUTION; CAUCASIAN; CLINICAL FEATURE; COHORT ANALYSIS; CONFERENCE PAPER; DIABETES MELLITUS; GENE MUTATION; GENETIC LINKAGE; GENOTYPE; HUMAN; HUMAN CELL; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MATURITY ONSET DIABETES MELLITUS; MOLECULAR GENETICS; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; SCHOOL CHILD; SEQUENCE ANALYSIS; TRANSACTIVATION;

EID: 0035122282     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.50.2007.s94     Document Type: Conference Paper

References (40)

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17. Frameshift mutation, A263fsinsGG, in the hepatocyte nuclear factor-1 beta gene associated with diabetes and renal dysfunction
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36. No evidence of linkage or diabetes-associated mutations in the transcription factors BETA2/NEUROD1 and PAX4 in type II diabetes in France
37. A high prevalence of glucokinase mutations in gestational diabetic subjects selected by clinical criteria
38. Mutation P29 1fsinsC in the transcription factor hepatocyte nuclear factor-1 alpha is dominant negative
39. Nonsense-mediated mRNA decay in health and disease
40. Natural history, genetics and pathogenesis of HNF-4α/MODY1: A 40-year prospective study of the RW pedigree