Synergistic transactivation of HNF-1α, HNF-3, and NF-I contributes to the activation of the liver-specific protein C gene

DNA and Cell Biology

Volumn 16, Issue 5, 1997, Pages 569-577

  Tsay, Woei ^a  

^a INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NUCLEAR FACTOR; NUCLEAR FACTOR I; PROTEIN C;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIVER CELL NUCLEUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; TISSUE SPECIFICITY; TRANSACTIVATION;

ANIMALIA;

EID: 0030953245     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1997.16.569     Document Type: Article

References (4)

1. BERG, L.-P., WHITE, D.A., ALHAQ, A., KAKKAR, V.V., and COOPER, D.N. (1994). Disruption of a binding site for hepatocyte nuclear factor-1 (HNF-1) in the protein C (PROC) gene promoter is associated with hereditary thrombophilia. Hum. Mol. Genet. 3, 2147-2152.
2. BRENNAN, R.G. (1993). The winged-helix DNA-binding motif: Another helix-turn-helix takeoff. Cell 74, 773-776.
3. CHIU, R., IMAGAWA, M., IMBRA, R.J., BOCKOVEN, J.R., and KARIN, M. (1987). Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters. Natures 329, 648-651.
4. CHOUARD, T., BLUMENFELD, M., BACH, I., VANDEKERCKHOVE, J., CEREGHINI, S., and YANIV, M. (1990). A distal dimerization domain is essential for DNA-binding by the atypical HNF1 homeodomain. Nucleic Acids Res. 18, 5853-5863.