메뉴 건너뛰기




Volumn 276, Issue 5 39-5, 1999, Pages

Regulation of α1-antitrypsin gene expression in human intestinal epithelial cell line Caco-2 by HNF-1α and HNF-4

Author keywords

Enterocyte differentiation; Hepatocyte nuclear factor 1 ; Hepatocyte nuclear factor 4

Indexed keywords

ALPHA 1 ANTITRYPSIN; CIS ACTING ELEMENT; DNA; DNA BINDING PROTEIN; MESSENGER RNA; NUCLEAR FACTOR; NUCLEAR FACTOR 1ALPHA; NUCLEAR FACTOR 4; RIBOZYME; TRANS ACTING FACTOR; UNCLASSIFIED DRUG;

EID: 33746471838     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.5.g1181     Document Type: Article
Times cited : (51)

References (60)
  • 1
    • 0018889401 scopus 로고
    • Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, alpha-1-antitrypsin, C8 and factor B
    • Alper, C. A., D. Raum, Z. L. Awdeh, B. H. Petersen, P. D. Taylor, and T. E. Starzl. Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, alpha-1-antitrypsin, C8 and factor B. Clin. Immunol. Immunopathol. 16: 84-89, 1980.
    • (1980) Clin. Immunol. Immunopathol. , vol.16 , pp. 84-89
    • Alper, C.A.1    Raum, D.2    Awdeh, Z.L.3    Petersen, B.H.4    Taylor, P.D.5    Starzl, T.E.6
  • 2
    • 0027382846 scopus 로고
    • More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing
    • Bach, I., and M. Yaniv. More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing. EMBO J. 12: 4229-4242, 1993.
    • (1993) EMBO J. , vol.12 , pp. 4229-4242
    • Bach, I.1    Yaniv, M.2
  • 3
    • 0024062728 scopus 로고
    • A variant nuclear protein in dedifferentiated hepatoma cells binds to the same functional sequences in the beta fibrinogen gene promoter as HNF-1
    • Baumhueter, S., G. Courtois, and G. R. Crabtree. A variant nuclear protein in dedifferentiated hepatoma cells binds to the same functional sequences in the beta fibrinogen gene promoter as HNF-1. EMBO J. 7: 2485-2493, 1988.
    • (1988) EMBO J. , vol.7 , pp. 2485-2493
    • Baumhueter, S.1    Courtois, G.2    Crabtree, G.R.3
  • 4
    • 0026561547 scopus 로고
    • Extinction of alpha-1-antitrypsin gene expression in somatic cell hybrids: Evidence for multiple controls
    • Bulla, G. A., V. DeSimone, R. Cortese, and R. E. K. Fournier. Extinction of alpha-1-antitrypsin gene expression in somatic cell hybrids: evidence for multiple controls. Genes Dev. 6: 316-327, 1992.
    • (1992) Genes Dev. , vol.6 , pp. 316-327
    • Bulla, G.A.1    DeSimone, V.2    Cortese, R.3    Fournier, R.E.K.4
  • 5
    • 0024061257 scopus 로고
    • A liver-specific factor essential for albumin transcription differs between differentiated and dedifferentiated rat hepatoma cells
    • Cereghini, S., M. Blumenfeld, and M. Yaniv. A liver-specific factor essential for albumin transcription differs between differentiated and dedifferentiated rat hepatoma cells. Genes Dev. 2: 957-974, 1988.
    • (1988) Genes Dev. , vol.2 , pp. 957-974
    • Cereghini, S.1    Blumenfeld, M.2    Yaniv, M.3
  • 6
    • 0023653288 scopus 로고
    • Factors involved in control of tissue-specific expression of albumin gene
    • Cereghini, S., M. Raymondjean, A. G. Carranca, P. Herbomel, and M. Yaniv. Factors involved in control of tissue-specific expression of albumin gene. Cell 50: 627-638, 1987.
    • (1987) Cell , vol.50 , pp. 627-638
    • Cereghini, S.1    Raymondjean, M.2    Carranca, A.G.3    Herbomel, P.4    Yaniv, M.5
  • 7
    • 0025290218 scopus 로고
    • Hepatocyte dedifferentiation and extinction is accompanied by a block in the synthesis of mRNA coding for the transcription factor HNF1/LFB1
    • Cereghini, S., M. Yaniv, and R. Cortese. Hepatocyte dedifferentiation and extinction is accompanied by a block in the synthesis of mRNA coding for the transcription factor HNF1/LFB1. EMBO J. 9: 2257-2263, 1990.
    • (1990) EMBO J. , vol.9 , pp. 2257-2263
    • Cereghini, S.1    Yaniv, M.2    Cortese, R.3
  • 8
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonucleases
    • Chirgwin, T. M., A. E. Przbyla, R. J. MacDonald, and W. J. Rutter. Isolation of biologically active ribonucleic acid from sources enriched in ribonucleases. Biochemistry 18: 5294-5301, 1979.
    • (1979) Biochemistry , vol.18 , pp. 5294-5301
    • Chirgwin, T.M.1    Przbyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 9
    • 0022397466 scopus 로고
    • Cell-specific expression of a transfected human alpha-1-antitrypsin gene
    • Ciliberto, G., L. Dente, and R. Cortese. Cell-specific expression of a transfected human alpha-1-antitrypsin gene. Cell 41: 531-540, 1985.
    • (1985) Cell , vol.41 , pp. 531-540
    • Ciliberto, G.1    Dente, L.2    Cortese, R.3
  • 10
    • 0023628342 scopus 로고
    • Interaction of a liver-specific nuclear factor with the fibrinogen and alpha-1-antitrypsin promoters
    • Courtois, G., J. G. Morgan, L. A. Campbell, G. Fourel, and G. R. Crabtree. Interaction of a liver-specific nuclear factor with the fibrinogen and alpha-1-antitrypsin promoters. Science 238: 688-692, 1987.
    • (1987) Science , vol.238 , pp. 688-692
    • Courtois, G.1    Morgan, J.G.2    Campbell, L.A.3    Fourel, G.4    Crabtree, G.R.5
  • 11
    • 0026027585 scopus 로고
    • HNF-1, a member of a novel class of dimerizing homeodomain proteins
    • Crabtree, G. R., and D. B. Mendel. HNF-1, a member of a novel class of dimerizing homeodomain proteins. J. Biol. Chem. 266: 677-680, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 677-680
    • Crabtree, G.R.1    Mendel, D.B.2
  • 12
    • 0027445682 scopus 로고
    • Inhibition of HIV-1 replication by ribozymes that show poor activity in vitro
    • Crissell, P., S. Thompson, and W. James. Inhibition of HIV-1 replication by ribozymes that show poor activity in vitro. Nucleic Acids Res. 21: 5251-5255, 1993.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 5251-5255
    • Crissell, P.1    Thompson, S.2    James, W.3
  • 13
    • 2642655139 scopus 로고
    • Cis- and trans-acting elements responsible for the cell-specific expression of the human alpha-1-antitrypsin gene
    • De Simone, V., G. Ciliberto, E. Hardon, G. Paonessa, F. Palla, L. Lundberg, and R. Cortese. Cis-and trans-acting elements responsible for the cell-specific expression of the human alpha-1-antitrypsin gene. EMBO J. 6: 2759-2766, 1987.
    • (1987) EMBO J. , vol.6 , pp. 2759-2766
    • De Simone, V.1    Ciliberto, G.2    Hardon, E.3    Paonessa, G.4    Palla, F.5    Lundberg, L.6    Cortese, R.7
  • 14
    • 0026731145 scopus 로고
    • Transcription factors and liver-specific genes
    • De Simone, V., and R. Cortese. Transcription factors and liver-specific genes. Biochim. Biophys. Acta 1132: 119-126, 1992.
    • (1992) Biochim. Biophys. Acta , vol.1132 , pp. 119-126
    • De Simone, V.1    Cortese, R.2
  • 15
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11: 1475-1489, 1983.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 16
    • 0028031296 scopus 로고
    • Expression of transcription factor HNF-4 in the extra-embryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst
    • Duncan, S. A., K. Manova, W. S. Chen, P. Hoodless, D. C. Weinst, R. F. Bachvarova, and J. E. Darnell, Jr. Expression of transcription factor HNF-4 in the extra-embryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. Proc. Natl. Acad. Sci. USA 91: 7598-7602, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7598-7602
    • Duncan, S.A.1    Manova, K.2    Chen, W.S.3    Hoodless, P.4    Weinst, D.C.5    Bachvarova, R.F.6    Darnell J.E., Jr.7
  • 17
    • 0032584567 scopus 로고    scopus 로고
    • Regulation of a transcription factor network required for differentiation and metabolism
    • Duncan, S. A., M. A. Navas, D. Dufort, J. Rossant, and M. Stoffel. Regulation of a transcription factor network required for differentiation and metabolism. Science 281: 692-695, 1998.
    • (1998) Science , vol.281 , pp. 692-695
    • Duncan, S.A.1    Navas, M.A.2    Dufort, D.3    Rossant, J.4    Stoffel, M.5
  • 18
    • 0024452687 scopus 로고
    • The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain
    • Frain, M., G. Swart, P. Monaci, A. Nicosia, S. Stampfli, R. Frank, and R. Cortese. The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain. Cell 59: 145-157, 1989.
    • (1989) Cell , vol.59 , pp. 145-157
    • Frain, M.1    Swart, G.2    Monaci, P.3    Nicosia, A.4    Stampfli, S.5    Frank, R.6    Cortese, R.7
  • 19
    • 0027204617 scopus 로고
    • HNF4 and HNF1 as well as a panel of hepatic functions are extinguished and re-expressed in parallel in chromosomally reduced rat hepatoma-human fibroblast hybrids
    • Griffo, G., C. Hamon-Benais, P. O. Angrand, M. Fox, L. West, O. Lecoq, S. Povey, D. Cassio, and M. Weiss. HNF4 and HNF1 as well as a panel of hepatic functions are extinguished and re-expressed in parallel in chromosomally reduced rat hepatoma-human fibroblast hybrids. J. Cell Biol. 121: 887-898, 1993.
    • (1993) J. Cell Biol. , vol.121 , pp. 887-898
    • Griffo, G.1    Hamon-Benais, C.2    Angrand, P.O.3    Fox, M.4    West, L.5    Lecoq, O.6    Povey, S.7    Cassio, D.8    Weiss, M.9
  • 20
    • 0026652705 scopus 로고
    • Constitutive and modulated expression of the human alpha-1-antitrypsin gene. Different transcriptional initiation sites used in three different cell types
    • Hafeez, W., G. Ciliberto, and D. H. Perlmutter. Constitutive and modulated expression of the human alpha-1-antitrypsin gene. Different transcriptional initiation sites used in three different cell types. J. Clin. Invest. 89: 1214-1222, 1992.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1214-1222
    • Hafeez, W.1    Ciliberto, G.2    Perlmutter, D.H.3
  • 21
    • 0024023932 scopus 로고
    • Two distinct factors interact with the promoter regions of several liver-specific genes
    • Hardon, E. M., M. Frain, G. Paonessa, and R. Cortese. Two distinct factors interact with the promoter regions of several liver-specific genes. EMBO J. 7: 1711-1719, 1988.
    • (1988) EMBO J. , vol.7 , pp. 1711-1719
    • Hardon, E.M.1    Frain, M.2    Paonessa, G.3    Cortese, R.4
  • 22
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S. N., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. R. Pease. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77: 51-59, 1989.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 24
    • 0005937986 scopus 로고
    • Implications of the three-dimensional structure of α1-antitrypsin for the structure and function of serpins
    • Huber, R., and R. W. Carrell. Implications of the three-dimensional structure of α1-antitrypsin for the structure and function of serpins. Biochemistry 117: 48-53, 1990.
    • (1990) Biochemistry , vol.117 , pp. 48-53
    • Huber, R.1    Carrell, R.W.2
  • 25
    • 0025944522 scopus 로고
    • Subtractive hybridization cloning of a tissue-specific extinguisher: TSE1 encodes a regulatory subunit of protein kinase A
    • Jones, K. W., M. N. Shapero, M. Chevrette, and R. E. K. Fournier. Subtractive hybridization cloning of a tissue-specific extinguisher: TSE1 encodes a regulatory subunit of protein kinase A. Cell 66: 861-872, 1991.
    • (1991) Cell , vol.66 , pp. 861-872
    • Jones, K.W.1    Shapero, M.N.2    Chevrette, M.3    Fournier, R.E.K.4
  • 26
    • 0030848766 scopus 로고    scopus 로고
    • Modulation of hepatic gene expression by hepatocyte nuclear factor I
    • Ktistaki, E., and I. Talianidis. Modulation of hepatic gene expression by hepatocyte nuclear factor I. Science 277: 109-111, 1997.
    • (1997) Science , vol.277 , pp. 109-111
    • Ktistaki, E.1    Talianidis, I.2
  • 28
    • 0028898120 scopus 로고
    • Role of the liver-enriched transcription factor HNF-1 alpha in expression of the CYP2E1 gene
    • Liu, S., and F. J. Gonzalez. Role of the liver-enriched transcription factor HNF-1 alpha in expression of the CYP2E1 gene. DNA Cell Biol. 14: 285-293, 1995.
    • (1995) DNA Cell Biol. , vol.14 , pp. 285-293
    • Liu, S.1    Gonzalez, F.J.2
  • 29
    • 0027340235 scopus 로고
    • A G→A substitution in an HNF-1 binding site in the human alpha-fetoprotein gene is associated with hereditary persistance of alpha-fetoprotein (HPAFP)
    • McVey, J. H., K. Michaelides, L. P. Hansen, M. Ferguson-Smith, S. Tilghman, R. Krumlauf, and E. D. G. Tuddenham. A G→A substitution in an HNF-1 binding site in the human alpha-fetoprotein gene is associated with hereditary persistance of alpha-fetoprotein (HPAFP). Hum. Mol. Genet. 2: 379-384, 1993.
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 379-384
    • McVey, J.H.1    Michaelides, K.2    Hansen, L.P.3    Ferguson-Smith, M.4    Tilghman, S.5    Krumlauf, R.6    Tuddenham, E.D.G.7
  • 30
    • 0026589377 scopus 로고
    • Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells
    • Mietus-Snyder, M., F. M. Sladek, G. S. Ginsburg, C. F. Kuo, J. A. Ladias, J. E. Darnell, and S. K. Karathanasis. Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. Mol. Cell. Biol. 12: 1708-1718, 1992.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1708-1718
    • Mietus-Snyder, M.1    Sladek, F.M.2    Ginsburg, G.S.3    Kuo, C.F.4    Ladias, J.A.5    Darnell, J.E.6    Karathanasis, S.K.7
  • 31
    • 0032557437 scopus 로고    scopus 로고
    • The HOXC11 homeodomain protein interacts with the lactase-phlorizin hydrolase promoter and stimulates HNF1-alpha-dependent transcription
    • Mitchelmore, C., J. T. Troelsen, H. Sjostrom, and O. Noren. The HOXC11 homeodomain protein interacts with the lactase-phlorizin hydrolase promoter and stimulates HNF1-alpha-dependent transcription. J. Biol. Chem. 273: 13297-13306, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13297-13306
    • Mitchelmore, C.1    Troelsen, J.T.2    Sjostrom, H.3    Noren, O.4
  • 32
    • 0027361105 scopus 로고
    • Cell-specific expression of alpha-1-antitrypsin in human intestinal epithelium
    • Molmenti, E. P., D. H. Perlmutter, and D. C. Rubin. Cell-specific expression of alpha-1-antitrypsin in human intestinal epithelium. J. Clin. Invest. 92: 2022-2034, 1993.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2022-2034
    • Molmenti, E.P.1    Perlmutter, D.H.2    Rubin, D.C.3
  • 33
    • 0027315712 scopus 로고
    • Evidence for an acute phase response in human intestinal epithelial cells
    • Molmenti, E. P., T. Ziambaras, and D. H. Perlmutter. Evidence for an acute phase response in human intestinal epithelial cells. J. Biol. Chem. 268: 14116-14124, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14116-14124
    • Molmenti, E.P.1    Ziambaras, T.2    Perlmutter, D.H.3
  • 34
    • 0024041297 scopus 로고
    • Two different liver-specific factors stimulate in vitro transcription from the human alpha-1-antitrypsin promoter
    • Monaci, P., A. Nicosia, and R. Cortese. Two different liver-specific factors stimulate in vitro transcription from the human alpha-1-antitrypsin promoter. EMBO J. 7: 2075-2087, 1988.
    • (1988) EMBO J. , vol.7 , pp. 2075-2087
    • Monaci, P.1    Nicosia, A.2    Cortese, R.3
  • 35
    • 0030662044 scopus 로고    scopus 로고
    • Human apolipoprotein B-transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes
    • Nielsen, L. B., S. P.A. McCormick, V. Pierotti, C. Tam, M. D. Gunn, H. Shizuya, and S. G. Young. Human apolipoprotein B-transgenic mice generated with 207-and 145-kilobase pair bacterial artificial chromosomes. J. Biol. Chem. 272: 29752-29758, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29752-29758
    • Nielsen, L.B.1    McCormick, S.P.A.2    Pierotti, V.3    Tam, C.4    Gunn, M.D.5    Shizuya, H.6    Young, S.G.7
  • 36
    • 0032579267 scopus 로고    scopus 로고
    • Identification of a goblet cell-specific enhancer element in the rat intestinal trefoil factor gene promoter bound by a goblet cell nuclear protein
    • Ogata, H., N. Inoue, and D. K. Podolsky. Identification of a goblet cell-specific enhancer element in the rat intestinal trefoil factor gene promoter bound by a goblet cell nuclear protein. J. Biol. Chem. 273: 3060-3067, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 3060-3067
    • Ogata, H.1    Inoue, N.2    Podolsky, D.K.3
  • 37
    • 0026354991 scopus 로고
    • The mechanisms by which a human apolipoprotein B gene enhancer and reducer interact with the promoter are different in cultured cells of hepatic and intestinal origin
    • Paulweber, B., and B. Levy-Wilson. The mechanisms by which a human apolipoprotein B gene enhancer and reducer interact with the promoter are different in cultured cells of hepatic and intestinal origin. J. Biol. Chem. 266: 24161-24168, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24161-24168
    • Paulweber, B.1    Levy-Wilson, B.2
  • 38
    • 0026329407 scopus 로고
    • Similarities and differences in the function of regulatory elements at the 5′-end of the human apolipoprotein B gene in cultured hepatoma (Hep G2) and colon carcinoma (CaCo-2) cells
    • Paulweber, B., M. A. Onasch, B. P. Nagy, and B. Levy-Wilson. Similarities and differences in the function of regulatory elements at the 5′-end of the human apolipoprotein B gene in cultured hepatoma (Hep G2) and colon carcinoma (CaCo-2) cells. J. Biol. Chem. 266: 24149-24160, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24149-24160
    • Paulweber, B.1    Onasch, M.A.2    Nagy, B.P.3    Levy-Wilson, B.4
  • 39
    • 0011067148 scopus 로고
    • α1-Antitrypsin: Structure, function, physiology
    • edited by A. Mackiewicz, I. Kushner, and H. Baumann. Miami, FL: CRC
    • Perlmutter, D. H. α1-Antitrypsin: structure, function, physiology. In: Acute Phase Proteins: Molecular Biology, Biochemistry, and Clinical Application, edited by A. Mackiewicz, I. Kushner, and H. Baumann. Miami, FL: CRC, 1993, p. 149-167.
    • (1993) Acute Phase Proteins: Molecular Biology, Biochemistry, and Clinical Application , pp. 149-167
    • Perlmutter, D.H.1
  • 40
    • 0021979206 scopus 로고
    • Expression of the alpha-1-proteinase inhibitor gene in human monocytes and macrophages
    • Perlmutter, D. H., F. S. Cole, P. Kilbridge, and T. Rossing. Expression of the alpha-1-proteinase inhibitor gene in human monocytes and macrophages. Proc. Natl. Acad. Sci. USA 82: 795-799, 1985.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 795-799
    • Perlmutter, D.H.1    Cole, F.S.2    Kilbridge, P.3    Rossing, T.4
  • 42
    • 0027316339 scopus 로고
    • Comparison of the patterns of expression of rat intestinal fatty acid binding protein/human growth hormone fusion genes in cultured intestinal epithelial cell lines and in the gut epithelium of transgenic mice
    • Rottman, J. N., and J. I. Gordon. Comparison of the patterns of expression of rat intestinal fatty acid binding protein/human growth hormone fusion genes in cultured intestinal epithelial cell lines and in the gut epithelium of transgenic mice. J. Biol. Chem. 268: 11994-12002, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11994-12002
    • Rottman, J.N.1    Gordon, J.I.2
  • 43
    • 0000778479 scopus 로고
    • Extraction, purification and analysis of messenger RNA from eukaryotic cells
    • Plainview, NY: Cold Spring Harbor Laboratory
    • Sambrook, J., E. F. Fritsch, and T. Maniatis. Extraction, purification and analysis of messenger RNA from eukaryotic cells. In: Molecular Cloning: A Laboratory Manual. Plainview, NY: Cold Spring Harbor Laboratory, 1989, p. 7.26-7.29.
    • (1989) Molecular Cloning: A Laboratory Manual , pp. 726-729
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 44
    • 0029033124 scopus 로고
    • A 20-nucleotide element in the intestinal fatty acid binding protein gene modulates its cell lineage-specific, differentiation-dependent, and cephalocaudal patterns of expression in transgenic mice
    • Simon, T. C., L. J. Roberts, and J. I. Gordon. A 20-nucleotide element in the intestinal fatty acid binding protein gene modulates its cell lineage-specific, differentiation-dependent, and cephalocaudal patterns of expression in transgenic mice. Proc. Natl. Acad. Sci. USA 92: 8685-8689, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8685-8689
    • Simon, T.C.1    Roberts, L.J.2    Gordon, J.I.3
  • 45
    • 0027662208 scopus 로고
    • Orphan receptor HNF-4 and liver-specific gene expression
    • edited by F. Tronch and M. Yaniv. Austin, TX: Landes
    • Sladek, F. M. Orphan receptor HNF-4 and liver-specific gene expression. In: Transcriptional Regulation of Liver Specific Genes, edited by F. Tronch and M. Yaniv. Austin, TX: Landes, 1994, p. 223-232.
    • (1994) Transcriptional Regulation of Liver Specific Genes , pp. 223-232
    • Sladek, F.M.1
  • 46
    • 0025690311 scopus 로고
    • Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
    • Sladek, F. M., W. Zhong, E. Lai, and J. E. Darnell, Jr. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev. 4: 2353-2365, 1990.
    • (1990) Genes Dev. , vol.4 , pp. 2353-2365
    • Sladek, F.M.1    Zhong, W.2    Lai, E.3    Darnell J.E., Jr.4
  • 47
    • 0030032310 scopus 로고    scopus 로고
    • An intestine-specific homeobox gene regulates proliferation and differentiation
    • Suh, E., and P. G. Traber. An intestine-specific homeobox gene regulates proliferation and differentiation. Mol. Cell. Biol. 16: 619-625, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 619-625
    • Suh, E.1    Traber, P.G.2
  • 48
    • 0023371227 scopus 로고
    • DNA sequence analysis with a modified bacteriophage T7 DNA polymerase
    • Tabor, S., and C. C. Richardson. DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. Proc. Natl. Acad. Sci. USA 84: 4767-4771, 1987.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 4767-4771
    • Tabor, S.1    Richardson, C.C.2
  • 49
    • 0029859978 scopus 로고    scopus 로고
    • Molecular pathogenesis of liver disease in alpha-1-antitrypsin deficiency
    • Teckman, J. H., D. Qu, and D. H. Perlmutter. Molecular pathogenesis of liver disease in alpha-1-antitrypsin deficiency. Hepatology 24: 1504-1516, 1996.
    • (1996) Hepatology , vol.24 , pp. 1504-1516
    • Teckman, J.H.1    Qu, D.2    Perlmutter, D.H.3
  • 50
    • 0019061278 scopus 로고
    • Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose
    • Thomas, P. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc. Natl. Acad. Sci. USA 77: 5201-5205, 1980.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 5201-5205
    • Thomas, P.1
  • 51
    • 0025718822 scopus 로고
    • Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4
    • Tian, J.-M., and U. Schibler. Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4. Genes Dev. 5: 2225-2234, 1991.
    • (1991) Genes Dev. , vol.5 , pp. 2225-2234
    • Tian, J.-M.1    Schibler, U.2
  • 52
    • 0029919065 scopus 로고    scopus 로고
    • Intestine-specific gene transcription
    • Traber, P. G., and D. G. Silberg Intestine-specific gene transcription. Annu. Rev. Physiol. 58: 275-297, 1996.
    • (1996) Annu. Rev. Physiol. , vol.58 , pp. 275-297
    • Traber, P.G.1    Silberg, D.G.2
  • 53
    • 0025991953 scopus 로고
    • Disruption of the LF-A1 and LF-B1 binding sites in the human alpha-1-antitrypsin gene has a differential effect during development in transgenic mice
    • Tripodi, M., C. Abbott, M. Vivian, R. Cortese, and R. Lovell-Badge. Disruption of the LF-A1 and LF-B1 binding sites in the human alpha-1-antitrypsin gene has a differential effect during development in transgenic mice. EMBO J. 10: 3177-3182, 1991.
    • (1991) EMBO J. , vol.10 , pp. 3177-3182
    • Tripodi, M.1    Abbott, C.2    Vivian, M.3    Cortese, R.4    Lovell-Badge, R.5
  • 54
    • 0026928723 scopus 로고
    • HNF1, a homeoprotein member of the hepatic transcription regulatory network
    • Tronche, F., and M. Yaniv. HNF1, a homeoprotein member of the hepatic transcription regulatory network. Bioessays 14: 579-587, 1992.
    • (1992) Bioessays , vol.14 , pp. 579-587
    • Tronche, F.1    Yaniv, M.2
  • 55
    • 0025247956 scopus 로고
    • The ontogeny of alpha-fetoprotein gene expression in the mouse gastrointestial tract
    • Tyner, A. L., R. Godbout, R. S. Compton, and S. M. Tilghman. The ontogeny of alpha-fetoprotein gene expression in the mouse gastrointestial tract. J. Cell Biol. 110: 915-927, 1990.
    • (1990) J. Cell Biol. , vol.110 , pp. 915-927
    • Tyner, A.L.1    Godbout, R.2    Compton, R.S.3    Tilghman, S.M.4
  • 56
    • 0028180450 scopus 로고
    • Hepatocyte nuclear factor-1 alpha (HNF-1 alpha) and HNF-1 beta regulate transcription via two elements in an intestine-specific promoter
    • Wu, G. D., L. Chen, K. Forslund, and P. G. Traber. Hepatocyte nuclear factor-1 alpha (HNF-1 alpha) and HNF-1 beta regulate transcription via two elements in an intestine-specific promoter. J. Biol. Chem. 269: 17080-17085, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17080-17085
    • Wu, G.D.1    Chen, L.2    Forslund, K.3    Traber, P.G.4
  • 59
    • 0030067113 scopus 로고    scopus 로고
    • Regulation of sucrase-isomaltase gene expression in human intestinal epithelial cells by inflammatory cytokines
    • Ziambaras, T., D. C. Rubin, and D. H. Perlmutter. Regulation of sucrase-isomaltase gene expression in human intestinal epithelial cells by inflammatory cytokines. J. Biol. Chem. 271: 1237-1242, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1237-1242
    • Ziambaras, T.1    Rubin, D.C.2    Perlmutter, D.H.3
  • 60
    • 0030634286 scopus 로고    scopus 로고
    • PCR-based construction of long hammerhead ribozymes
    • Zillman, M., and G. Robinson. PCR-based construction of long hammerhead ribozymes. Methods Mol. Biol. 74: 131-139, 1997.
    • (1997) Methods Mol. Biol. , vol.74 , pp. 131-139
    • Zillman, M.1    Robinson, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.