Effect of menstrual cycle on mucosal immunity to SHIV within the reproductive tract of baboons (Papio anubis): Preliminary findings

Journal of Medical Primatology

Volumn 32, Issue 3, 2003, Pages 161-169

  Ochiel, Daniel O ^a   Wango, E O ^a   Kigondu, C S ^a   Otsyula, M G ^b  

^a UNIVERSITY OF NAIROBI   (Kenya)

^b INSTITUTE OF PRIMATE RESEARCH   (Kenya)

Author keywords

Cervicovaginal lavage; Estrogen; Human immunodeficiency virus 1; Immunoglobulin A; Immunoglobulin G; Mucosal antibodies; Progesterone; Simian immunodeficiency virus

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; BABOON; CONTROLLED STUDY; CORRELATION ANALYSIS; EXPERIMENTAL INFECTION; FEMALE; FEMALE GENITAL SYSTEM; HORMONE DETERMINATION; HUMAN IMMUNODEFICIENCY VIRUS; HUMORAL IMMUNITY; IMMUNE RESPONSE; INFECTION SENSITIVITY; MENSTRUAL CYCLE; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR; SEROLOGY; SEXUAL TRANSMISSION; SIMIAN IMMUNODEFICIENCY VIRUS; VERTICAL TRANSMISSION; VIRUS LOAD; VIRUS SHEDDING; VIRUS TRANSMISSION;

ANIMALS; ANTIBODIES, VIRAL; CERVIX UTERI; ESTRADIOL; FEMALE; GENITALIA, FEMALE; HIV; HIV ANTIBODIES; IMMUNITY, MUCOSAL; MENSTRUAL CYCLE; PAPIO; PROGESTERONE; SIMIAN IMMUNODEFICIENCY VIRUS; VAGINA;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; PAPIO; PAPIO ANUBIS; PAPIO HAMADRYAS; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN-HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0037854517     PISSN: 00472565     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0684.2003.00019.x     Document Type: Article

References (39)

1. AL-HARTHI L, WRIGHT DJ, ANDERSON D, COHEN M, MATITY A-D, COHN J, CU-UVIN S, BURNS D, REICHELD-ERFER P, BECKNER S, KOVACS A, LANDAY A: The impact of the ovulatory cycle on cytokine production: evaluation of systemic, cervicovaginal and salivary compartments. J Interferon Cytokine Res 20:719-724, 2000.
2. ALEXANDER MJ: Sexual transmission of human immuno-deficiency virus: virus entry into the male and female genital tract. Fert Steril 54:1-18, 1990.
3. ALLAN JS, RAY P, BOUSSARD S, WHITEHEAD E, HUBBARD G, BUTLER T, BRASKY K, LUCIN P, CHENG-MAYER C, LEVY JA, STEIMER K, LI J, SODROSKI J, GARCIA-MOLL MI: Infection of baboons with simian/Human Immuno-deficiency viruses. J Acquir Immune Defic Syndr Hum Retrovirol 9(s):429-441, 1995.
4. BELEC L, TEVI-BENISSAN C, DUCRE J, MOHAMMED AS, PRAZUCK T, GILQUIN J, KANGA JM, PILOT J: Comparison of Cervicovaginal humoral immunity of clinically assymptomatic (CDC A1 and A2 category) patients with HIV-1 and HIV-2 infection. J Clin Immunol 16:12-20, 1996.
5. COLLMAN R, BALIET JW, GREGORY SA, FRIEDMAN H, KOLSON DL, NATHANSON N, SRINIVASAN A: An infectious molecular clone of unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. J Virol 66:7517-7521, 1992.
6. DORELL L, HESSELL AJ, WANG M, WHITTLE H, SABALLY S, ROWLAND-JONES S, BURTON DR, PARREN PW: Absence of specific mucosal antibody responses in HIV-exposed uninfected sex workers from the Gambia. AIDS 14:1117-1122, 2000.
7. ELEY RM, BAMBRA CS: Basic reproductive biology of the baboon. In: Veterinary Management and Research Techniques for Reproductive Studies in the Baboon: A Practical Approach. BAMBRA CS. (ed.). Nairobi: National Museums of Kenya 29-40, 1993.
8. FIORE JR, LADDAGO V, LEPERA A, LA GRASTA L, DI STEFANO M, SARACINO A, LOPALCO P, PASTORE G, ANGARANO G: Limited secretory-IgA response in cervicovaginal secretions from HIV-1 infected, but not high risk seronegative women: lack of correlation to genital viral shedding. New Microbiol 23:85-92, 2000.
9. HARMOVICI F, MAYER KH, ANDERSON DJ: Quantitation of HIV-1 specific IgG, IgA and IgM antibodies in human genital tract secretions. J Acquir Immune Defic Syndr Hum Retrovirol 15:185-191, 1997.
10. HENDRICKX AG, KRAEMER DC: Reproduction. In: Reproductive Embryology of the Baboon. HENDRICKX AG (ed.). Chicago: University of Chicago Press 3-30, 1971.
11. KATO H, BUKAWA H, HAGIWARA E, XIN K-Q, HAMAJIMA K, KAWAMOTO S, SUGIYAMA M, SUGIYAMA M, MODA E, MISHIZAKI M, OKUDA K: Rectal and vaginal immunization with macromolecular multicomponent peptide vaccine candidate for HIV-1 infection induces HIV-1-specific protective immune responses. Vaccine 18:1151-1160, 2000.
12. KAUL R, TRABATTONI D, BWAYO JJ, ARIENTI D, ZAGLIAN A, MWANGI FM, KARIUKI C, NGUGI EN, MACDONALD KS, BALL TB, CLERICI M, PLUMMER FA: HIV-I-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers. AIDS 13:23-29, 1999.
13. KAZLOWSKI PA, CU-UVIN S, NEUTRA MR, FLANIGAN TP: Mucosal vaccination strategies for women. J Infect Dis 179(Suppl 3):S493-S498, 1999.
14. KLINDLT TJ, HIRSCH VM, JOHNSON PR, SAWASDIKOSOL S: Animal models for acquired immunodeficiency syndrome. Adv Immunol 52:425-474, 1992.
15. KLING RO, WESTFAHL KP: Steroid changes during the menstrual cycle of the baboon (Papio cynocephalus) and human. Biol Reprod 18:392-400, 1978.
16. KLINGER JM, HIMATHONGKHAM S, LEGG H, LUCIW PA, BARNETT SW: Infection of baboons with a Simian Immunodeficiency Virus/HIV-1 chimeric virus constructed with an HIV-1 Thai subtype E envelope. AIDS 12: 849-857, 1998.
17. KOVACS A, CHAN LS, CHEN ZC, MEYER WA, MUDERS-PACH L, YOUNG M, ANASTOS K, LEVINE AM: HIV-1 RNA in plasma and genital tract secretions in women infected with HIV-1. J Acquir Immune Defic Syndr 22:124-131, 1999.
18. KUTTEH WH, MESTECKY J: Secretory immunity in the female reproductive tract. Am J Reprod Immunol 31: 40-46, 1994.
19. KUTTEH WH, PRINCE SJ, HAMMOND KR, KUTTEH CC, MESTECKEY J: Variations in immunoglobulins and IgA subclasses of human uterine cervical secretions around the time of ovulation. Clin Exp Immunol 103:538-542, 1996.
20. LEHNER T, BERMEIR LA, PAGOTIODI C, TAO L, BROOKES R, KLAVINSKI LS, WORD RG, HUSSAIN L, GEARING AJH, ADAMS SE: Induction of mucosal and sytemic immunity to a recombinant Simian Immunodeficiency viral protein. Science 258:1365-1369, 1992.
21. LU XS, BELEC L, PILLOT J: Anti-gp160 IgG and IgA antibodies associated with a large increase in total IgG in cervicovaginal secretions from human immunodefieciency virus type-1 infected women. J Infect Dis 167:1189-1192, 1993.
22. LU FX, MA Z, ROURKE T, SRINIVASAN S, MCCHESNEY M, MILLER CJ: Immunoglobulin concentrations and antigen-specific antibody levels in cervicovaginal lavages of rhesus macaques are influenced by the stage of the menstrual cycle. Infect Immun 67:6321-6328, 1999.
23. LU FX: Predominate HIV1-specific IgG activity in various mucosal compartments of HIV1-infected individuals. Clin Immunol 97:59-68, 2000.
24. LU Y, BROSIO B, LAFAILE M, LI J, COLLMAN RG, SODROSKI J, MILLER CJ: Vaginal transmission of chimeric simian/human immunodeficiency viruses in rhesus macaques. J Virol 70:3045-3050, 1996.
25. MARX PA, SPIRA AI, DAILEY PJ, VEAZEY RS, LACKNER AA, MAHONEY CJ, MILLER CJ, CLAYPOOL LE, HO DD, ALEXANDER NY: Progesterone implants enhance SIV vaginal transmission and early virus load. Nat Med 2:1084-1089, 1996.
26. MUSEY L, HU Y, ECKERT L, CHRISTENSEN M, KARCHMER T, MCELRATH MJ: HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women. J Exp Med 185:293-303, 1997.
27. OTSYULA MG, MILLER CJ, MARTHAS ML, VAN ROMPAY KKA, COLLINS JR, PEDERSEN NC, MCCHESNEY MB: Virus-induced immunosuppression is linked to rapidly fatal disease in infant rhesus macaques infected with simian immmunodeficiency virus. Pediatr Res 36:630-636, 1996.
28. QUESNEL A, CU-UVIN S, MURPHY D, ASHLEY RL, FLANIGAN T, NEUTRA MR: Comparative analysis of methods for collection and measurement of immunoglobulins in cervical and vaginal secretions of women. J Immunol Methods 202:153-161, 1997.
29. REIHMAN KA, LI JT, VASS G, LEKUTIS C, TENNER-RACZ K, LIN W, MONTEFIORI DC, LEE-PARRITZ DE, LU Y, COLLMAN RG, SODROSKI J, LETVIN NL: An env gene derived from a primary immunodeficiency virus type1 isolate confers high replicative capacity to a chimeric Simian/Human Immunodeficiency virus in rhesus monkeys. J Virol 7:3198-3206, 1996.
30. SHAHEEN F, SISON AV, MCINTOSN L, MUKHTAR M, POMERATZ RJ: Analysis of HIV-1 in the cervicovaginal secretions and blood of pregnant and non-pregnant women. J Hum Virol 2:154-166, 1999.
31. SHAIKH AA, CELAYA CL, GOMEZ I, SHAIKH SA: Temporal relationship of hormonal peaks to ovulation and sex skin deturgescence in the baboon. Primates 23:444-452, 1982.
32. SMITH SM, BASKIN GB, MARX PA: Estrogen protects against vaginal transmission of Simian Immunodeficiency Virus. J Infect Dis 182:708-715, 1997.
33. STEVENS V: Some reproductive studies in the baboon. Human Reprod Update 3:533-540, 1997.
34. SUFI SB, DONALDSON A, JEFFCOATE SL: WHO Programme for the Provision of Matched Assay Reagents for the Radioimmunoassay of Hormones in Reproductive Physiology: A Laboratory Manual. Cambridge University Press, Cambridge, UK 1997.
35. UVIN SC, CALIENDO AM: Cervicovaginal human immunodeficiency virus secretions and plasma viral load in human immunodeficiency virus-seropositive women. Obstet Gynecol 90:739-743, 1997.
36. WILDT DE, DOYLE LL, STONE SC, HARRISON RM: Correlation of perineal swelling with serum ovarian hormone levels, vaginal cytology and ovarian follicular development during the baboon reproductive cycle. Primates 18:261-270, 1977.
37. WIRA CR, KAUSHIC C: Mucosal immunity in the female reproductive tract: effects of sex hormones and immune recognition and responses. In: Mucosal Vaccines: New Trends in Immunization. Kyono H, Ogra PL & McGhee JR (eds). NY: Academic Press 375-388, 1996.
38. WIRA CR, KAUSHIC C, RICHARDSON J: Role of sex hormones and cytokines in regulating the mucosal immune system in the female reproductive tract. In: Handbook of Mucosal Diseases. Ogra PL, Mestecky J, Lamm ME, Strober W, McGhee JR & Bienenstock J (eds). NY: Academic Press 1449-1461, 1999.
39. WIRA CR, SULLIVAN DA: Estradiol and progesterone regulation of immunoglobulin A and G and secretory component in cervicovaginal secretions of the rat. Biol Reprod 32:90-95, 1985.