Comparison of cervicovaginal humoral immunity in clinically asymptomatic (CDC A1 and A2 category) patients with HIV-1 and HIV-2 infection

Journal of Clinical Immunology

Volumn 16, Issue 1, 1996, Pages 12-20

  Bélec, Laurent ^a,b   Tévi Bénissan, Carol ^b   Dupré, Thiérry ^b   Mohamed, Ali Si ^b   Prazuck, Thiérry ^c   Gilquin, Jacques ^b   Kanga, Jean Marie ^d   Pillot, Jacques ^a  

^a INSTITUT PASTEUR   (France)

^b HÔPITAL BROUSSAIS   (France)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^d CENTRE HOSPITALIER UNIVERSITAIRE DE TREICHVILLE   (Côte d’Ivoire)

Author keywords

Cervicovaginal immunity; HIV 1; HIV 2

Indexed keywords

GLYCOPROTEIN GP 105; GLYCOPROTEIN GP 160; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PRIORITY JOURNAL; VAGINA MUCOSA; VAGINA SECRETION;

ADULT; CERVIX UTERI; FEMALE; GENE PRODUCTS, ENV; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP160; HIV INFECTIONS; HIV-1; HIV-2; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MIDDLE AGED; SERUM ALBUMIN; VAGINA;

EID: 0030063139     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01540968     Document Type: Article

References (43)

1. De Cock KM, Brun-Vézinet F, Soro B: HIV-1 and HIV-2 infections and AIDS in West Africa. AIDS 5 (Suppl 1):S21-S28, 1991
2. De Cock KM, Adjorlolo G, Ekpini E, Sibailly T, Kouadio J, Maran M, Brattegaard K, Vetter KM, Doorly R, Gayle HD: Epidemiology and transmission of HIV-2. Why there is no HIV-2 pandemic. JAMA 270:2083-2086, 1993
3. Marlink R, Kanki P, Thior I, Travers K, Eisen G, Siby T, Traore I, Hsieh C-C, Ciré Dia M, Gueye E-H, Hellinger J, Guèye-Ndiaye A, Sankalé J-L, Ndoye I, Mboup S, Essex M: Reduced rate of disease development after HIV-2 infection as compared to HIV-1. Science 265:1587-1590, 1994
4. De Cock KM, Brun-Vézinet F: Epidemiology of HIV-2 infection. AIDS 3 (Suppl 1):S89-S95, 1989
5. Kanki FJ, Travers KU, MBoup S, Hsieh C-C, Marlink RG, Gueye-Ndiaye A, Siby T, Thior I, Hernandez-Avila M, Sankalé J-L, NDoye I, Essex ME: Slower heterosexual spread of HIV-2 than HIV-1. Lancet 343:943-946, 1994
6. Möst J, Spötl L, Sarcletti M, Vogetseder W, Dierich MP, Zangerle R: Differences in heterosexual transmission of HIV-1 and HIV-2. Lancet 344:1572-1573, 1994
7. Simon F, Matheron S, Tamalet C, Loussert-Ajaka I, Bartczack S, Pépin JM, Dhiver C, Gamba E, Elbim C, Gastaut JA, Saimot AG, Brun-Vézinet F: Cellular and plasma viral load in patients infected with HIV-2. AIDS 7:1411-1417, 1993
8. Archibald DW, Witt DJ, Craven DE, Vogt MW, Hirsch MS, Essex M: Antibodies to human immunodeficiency virus in cervical secretions from women at risk for AIDS. J Infect Dis 156:240-241, 1987
9. Belec L, Georges AJ, Steenman G, Martin PMV: Antibodies to human immunodeficiency virus in vaginal secretion of heterosexual women. J Infect Dis 160:385-391, 1989
10. O'Shea S, Cordery M, Barrett WY, Richman DD, Bradbeer C, Banatvala JE: HIV excretion patterns and specific antibody responses in body fluids. J Med Virol 31:291-296, 1990
11. Lu X-S, Bélec L, Pillot J: Anti-gp160 IgG and IgA antibodies associated with a large increase in total IgG in cervicovaginal secretions from human immunodeficiency virus type-1 infected women. J Infect Dis 167:1189-1192, 1993
12. Bélec L, Grésenguet G, Dragon M-A, Meillet D, Pillot J: Detection of antibodies to human immunodeficiency virus in vaginal secretions by immunoglobulin G antibody capture enzyme-linked immunosorbent assay: Application to detection of seminal antibodies after sexual intercourse. J Clin Microbiol 32:1249-1255, 1994
13. Bélec L, Tévi-Bénissan C, Lu X-L, Prazuck T, Pillot J: Local synthesis of IgG to HIV within the female and male genital tracts during asymptomatic and pre-AIDS stages of HIV infection. AIDS Res Hum Retrovirus 11:719-729, 1995
14. Bélec L, Gherardi R, Payan C, Prazuck T, Tévi-Bénissan C, J-E Malkin, Pillot J: HIV-enhancing proinflammatory cytokines in cervicovaginal secretions from normal and HIV-infected women. Cytokine 7:568-574, 1995
15. Bélec L, Meillet D, Gaillard O, Prazück T, Michel E, Ngondi-Ekome J, Pillot J: Decreased cervicovaginal production of both IgA1 and IgA2 subclasses in women with AIDS. Clin Exp Immunol 101:100-106, 1995
16. Belec L, Peghini M, Georges AJ, Barabe P, Martin PMV: Antibodies to HIV-2 in genital secretions. Res Virol 140:15-21, 1989
17. World Health Organization: Proposed WHO criteria for interpreting results from Western blot assays for HIV-1, HIV-2 and HTLV-I/HTLV-II. Wkly Epidem Rec 37:281-283, 1990
18. Bélec L, Meillet D, Levy M, Georges AJ, Tevi-Benissan C, Pillot J: Dilution assessment of cervico-vaginal secretions obtained by vaginal washing for immunological assays. Clin Diag Lab Immunol 2:57-61, 1995
19. Lu X-S, Delfraissy JF, Grangeot-Keros L, Rannou MT, Pillot J: Rapid and constant detection of HIV antibody response in saliva of HIV infected patients; selective distribution of anti-HIV activity in the IgG isotype. Res Virol 145:369-377, 1994
20. Weiblen BJ, Schumacher RT, Hoff R: Detection of IgM and IgA antibodies after removal of IgG with recombinant protein G. J Immunol Methods 126:199-204, 1990
21. Jonard PP, Rambaud JC, Dive C, Vaerman JP, Gallan A, Delacroix DL: Secretion of immunoglobulins and plasma proteins from the jejunal mucosa. Transport rate and origin of polymeric immunoglobulin A. J Clin Invest 74:525-535, 1984
22. Bouvet J-P, Bélec L, Pirès R, Pillot J: Immunoglobulin G antibodies in human vaginal secretions after parenteral vaccination. Infect Immun 62:3957-3961, 1994
23. Kutteh WH, Mestecky J: Secretory immunity in the female reproductive tract. Am J Reprod Immunol 31:40-46, 1994
24. Brandtzaeg P, Christiansen E, Müller F, Purvis K: Humoral immune response pattern of human mucosae, including the reproductive tracts. In Local Immunity in Reproductive Tract Tissues, PD Griffin, PM Johnson (eds). Oxford University Press, Oxford, 1993, pp 97-130
25. Lim SG, Condez A, Lee CA, Johnson MA, Elia C, Poulter LW: Loss of mucosal CD4 lymphocytes in an early feature of HIV infection. Clin Exp Immunol 92:448-454, 1993
26. Janoff EN, Jackson S, Wahl SM, Thomas K, Peterman JH, Smith PD: Intestinal mucosal immunoglobulins during human immunodeficiency virus type 1 infection. J Infect Dis 170:299-307, 1994
27. Miller CJ, Kang DW, Marthas M, Moldoveanu Z, Kiyono H, Marx P, Eldridge JH, Mestecky J, McGhee JR: Genital secretory immune response to chronic simian immunodeficiency virus (SIV) infection: A comparison between intravenously and genitally inoculated rhesus macaques. Clin Exp Immunol 88:520-526, 1992
28. Archibald DW, Hebert CA, Alger LS, Johnson JP: Detection of HIV-specific antibodies in saliva and cervical secretions. Vaccine Res 1:215-219, 1992
29. Brandtzaeg P: Distribution and characteristics of mucosal immunoglobulin-producing cells. In Handbook of Mucosal Immunology, PL Ogra, W Strober, J Mestecky, JR McGhee, ME Lamm, J Bienenstock (eds). San Diego, CA, Academic Press, 1994, pp 251-262
30. Hénin Y, Mandelbrot L, Henrion R, Prainbaud R, Coulaud JP, Montagnier L: Virus excretion in the cervico-vaginal secretions of pregnant and non pregnant HIV-infected women. J AIDS 6:72-75, 1993
31. Clemetson DBA, Moss GB, Willerford DM, Hensel M, Emonyi W, Holmes KK, Plummer F, Ndinya-Achola J, Roberts PL, Hillier S, Kreiss JK: Detection of HIV DNA in cervical and vaginal secretions. Prevalence and correlates among women in Nairobi, Kenya. JAMA 269:2860-2864, 1993
32. Pomerantz RJ, De la Monte S, Donegan SP, Rota TR, Vogt MW, Craven DE, Hirsch MS: Human immunodeficiency virus (HIV) infection of the uterine cervix. Ann Intern Med 108:321-327, 1988
33. Nuovo GJ, Forde A, Mac Connell P, Fahrenwald R: In situ detection of PCR-amplified HIV-1 nucleic acids and tumor necrosis factor cDNA in cervical tissues. Am J Pathol 143:40-48, 1993
34. Van de Perre P, De Clercq A, Cogniaux-Leclerc J, Nzaramba D, Butzler J-P, Sprecher-Goldberger S: Detection of HIV p17 antigen in lymphocytes but not epithelial cells from cervicovaginal secretions of women seropositive for HIV: Implications for heterosexual transmission of the virus. Genitourin Med 64:30-33, 1988
35. Tedder RS, O'Connor T, Hughes A, N'Jie H, Corrah T, Whittle H: Envelope cross reactivity in Western blot for HIV-1 and HIV-2 may not indicate dual infection. Lancet 2:927-930, 1988
36. De Cock KM, Porter A, Kouadio J, Maran M, Lafontaine M-F, Gershy-Damet C-M, Hyeward WL, George R: Cross-reactivity on Western blots in HIV-1 and HIV-2 infections. AIDS 15:859-863, 1991
37. Guyader M, Emerman M, Sonigo P, Clavel F, Montagnier L, Alizon M: Genome organization and transactivation of the human immunodeficiency virus type 2. Nature 326:662-669, 1987
38. Weiss RA, Clapham PR, Weber JN, Whitby D, Tedder RS, O'Connor T, Chamaret S, Montagnier L: HIV-2 antisera cross-neutralize HIV-1. AIDS 2:95-100, 1988
39. Rayfield M, De Cock K, Heyward W, Golstein L, Krebs J, Kwok S, Lee S, McCormick J, Moreau JM, Odehouri K, Schochetman G, Sninsky J, Ou C-Y: Mixed human immunodeficiency virus (HIV) infection in an individual: Demonstration of both HIV type 1 and type 2 proviral sequences by using polymerase chain reaction. J Infect Dis 158:1170-1176, 1988
40. George JR, Ou C-Y, Parekh B, Brattegaard K, Brown V, Boateng E, De Cock KM: Prevalence of HIV-1 and HIV-2 mixed infections in Côte d'Ivoire. Lancet 340:337-339, 1992
41. Travers K, Mboup S, Marlink R, Guèye-Ndiaye A, Siby T, Thior I, Traore I, Dieng-Sarr A, Sankalé J-L, Mullins C, Ndoye I, Hseih C-C, Essex M, Kanki P: Natural protection against HIV-1 infection provided by HIV-2. Science 268:1612-1615, 1995
42. Grankvist O, Bredberg-Radèn U, Gustafsson A, Albert J, Albino P, Andreasson PA, Nauclér A, Biberfeld G, Wadell G: Improved detection of HIV-2 DNA in clinical samples using a nested primer-based polymerase chain reaction. J AIDS 5:286-293, 1992
43. Loussert-Ajaka I, Simon F, Farfara I, Houhou N, Couto-Fernandez J, Dazza MC, Brun-Vézinet F: Comparative study of single and nested PCR for the detection of proviral HIV2 DNA. Res Virol 145:337-342, 1994