An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys

Journal of Virology

Volumn 70, Issue 5, 1996, Pages 3198-3206

  Reimann, Keith A ^a,f   John, T L I ^a   Voss, Gerald ^a   Lekutis, Christine ^a   Tenner Racz, Klara ^b   Racz, Paul ^b   Lin, Wenyu ^a   Montefiori, David C ^c   Lee Parritz, David E ^a   Yichen, L U ^d   Collman, Ronald G ^e   Sodroski, Joseph ^a   Letvin, Norman L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d Virus Research Institute Inc Cambridge   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY TITER; ARTICLE; EFFECTOR CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; IN SITU HYBRIDIZATION; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; RHESUS MONKEY; VIREMIA; VIRUS ENVELOPE; VIRUS ISOLATION; VIRUS REPLICATION;

EID: 9244224075     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.5.3198-3206.1996     Document Type: Article

References (40)

1. + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J. Virol. 68:6103-6110.
2. Clark, S. J., M. S. Saag, W. D. Decker, S. Campbell-Hill, J. L. Roberson, P. J. Veldkamp, J. C. Kappes, B. H. Hahn, and G. M. Shaw. 1991. High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection. N. Engl. J. Med. 324:954-960.
3. Collman, R., J. W. Balliet, S. A. Gregory, H. Friedman, D. L. Kolson, N. Nathanson, and A. Srinivasan. 1992. An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. J. Virol. 66:7517-7521.
4. Daar, E. S., T. Moudgil, R. D. Meyer, and D. D. Ho. 1991. Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection. N. Engl. J. Med. 324:961-964.
5. D'Souza, M. P., P. Durda, C. V. Hanson, G. Milman, and collaborating investigators. 1991. Evaluation of monoclonal antibodies to HIV-1 by neutralization and serological assays: an international collaboration. AIDS 5:1061-1070.
6. Fisher, A. G., E. Collalti, L. Ratner, R. C. Gallo, and F. Wong-Staal. 1985. A molecular clone of HTLV-III with biological activity. Nature (London) 316:262-265.
7. Fisher, R. 1991. CD4 molecules: rationale and potential as antiviral agents. AIDS Res. Rev. 1:289-300.
8. Fox, C. H., K. Tenner-Raez, P. Racz, A. Firpo, P. A. Pizzo, and A. S. Fauci. 1991. Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA. J. Infect. Dis. 164:1051-1057.
9. Fultz, P. N. 1993. Nonhuman primate models for AIDS. Clin. Infect. Dis. 17(Suppl. 1):S230-S235.
10. Hirsch, V. M., G. Dapolito, P. R. Johnson, W. R. Elkins, W. T. London, R. J. Montali, S. Goldstein, and C. Brown. 1995. Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogemcity correlates with extent of in vivo replication. J. Virol. 69:955-967.
11. Hirsch, V. M., J. E. Martin, G. Dapolito, W. R. Elkins, W. T. London, S. Goldstein, and P. R. Johnson. 1994. Spontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus. J. Virol. 68:2649-2661.
12. Igarashi, T., R. Shibata, F. Hasebe, Y. Ami, K. Shinohara, T. Komatsu, C. Stahl-Henning, H. Petry, G. Hunsmann, T. Kuwata, M. Jin, A. Adachi, T. Kurimura, M. Okada, T. Miura, and M. Hayami. 1994. Persistent infection with SIVmac chimeric virus having tat, rev, vpu. env and nef of HIV type 1 in macaque monkeys. AIDS Res. Hum. Retroviruses 10:1021-1029.
13. Javaherian, K., A. J. Langlois, S. Schmidt, M. Kaufmann, N. Cates, J. P. Langedijk, R. H. Meloen, R. C. Desrosiers, D. P. W. Borns, D. P. Bolognesi et al. 1992. The principal neutralization determinant of simian immunodeficiency virus differs from that of human imrmmodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 89:1418-1422.
14. Joling, P., L. J. Bakker, J. A. G. Van Strijp, T. Meerloo, L. de Graaf, M. E. M. Dekker, J. Goudsmit, J. Verhoef, and H.-J. Schurman. 1993. Binding of human immunodeficiency virus type-1 to follicular dendritic cells in vitro is complement dependent. J. Immunol. 150:1065-1073.
15. Kanki, P. J., M. F. McLane, N. W. King, Jr., N. L. Letvin, R. D. Hunt, P. Sehgal, M. D. Daniel, R. C. Desrosiers, and M. Essex. 1985 Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III. Science 228:1199-1201.
16. Kim, F. M., D. L. Kolson, J. M. Balliet, A. Srinivasan, and R. G. Collman. 1995. V3-independent determinants of macrophage tropism in a primary human immunodeficiency virus type 1 isolate. J. Virol. 69:1755-1761.
17. Koup, R. A., J. T. Safrit, Y. Cao, C. A. Andrews, G. McLeod, W. Borkowsky, C. Farthing, and D. D. Ho. 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome, J. Virol. 68:4650-4655.
18. Letvin, N. L. 1992 Animal models for the study of human immunodeficiency virus infections. Curr. Opin Immunol. 4:481-485.
19. Letvin, N. L., J. Li, M. Halloran, M. P. Cranage, E. W. Rud, and J. Sodroski. 1995. Prior infection with a nonpathogenic chimeric simian-human immunodeficiency virus does not efficiently protect macaques against challenge with simian immunodeficiency virus. J. Virol. 69:4569-4571.
20. Li, J., M. Halloran, C. I. Lord, A. Watson, J. Ranchalis, M. Fung, N. L. Letvin, and J. G. Sodroski. 1995. Persistent infection of macaques with simian-human immunodeficiency viruses. J Virol. 69:7061-7071.
21. mac virus that expresses the HIV-1 envelope glycoproteins. J. Acquired Immune Defic. Syndr. 5:639-646.
22. Luciw, P. A., E. Pratt-Lowe, K. E. S. Shaw, J. A. Levy, and C. Cheng-Mayer. 1995. Persistent infection of rhesus macaques with T-cell-Iine-tropic and macrophage-tropic clones of simian/human immunodeficiency viruses (SHIV). Proc. Natl. Acad. Sci. USA 92:7490-7494.
23. Meyers, G., B. Korber, S. Wain-Hobson, and R. F. Smith (ed.). 1993. Human retroviruses and AIDS 1993. Los Alamos National Laboratory, Los Alamos, N.Mex.
24. Montefiori, D. C., B. S. Graham, J. Y. Zhon, J. T. Zhou, and J. M. Ahearn. 1994. Binding of human immunodeficiency virus type 1 to the C3b/C4b receptor, CRI (CD35), and red blood cells in the presence of envelopespecific antibodies and complement J. Infect. Dis. 170:429-432.
25. Montefiori, D. C., W. E. Robinson, Jr., S. S. Schuffinan, and W. M. Mitchell. 1988. Evaluation of antiviral drugs and neutralizing antibodies against human immunodeficiency virus by a rapid and sensitive microtiter infection assay. J. Clin. Microbiol. 26:231-235.
26. Montefiori, D. C, J. Zhon, and D. I. Shaff. 1992. CD4-mdependent binding of HIV-1 to the B lymphocyte receptor CR2 (CD21) in the presence of complement and antibody. Clin. Exp. Immunol. 90:383-389.
27. Mon, K., D. J. Ringler, T. Kodama, and R. C. Desrosiers. 1992. Complex determinants of macrophage tropism in env of simian immunodeficiency virus. J. Virol. 66:2067-2075.
28. Marphy-Corb, M., L. N. Martin, S. R. S. Rangan, G. B. Baskin, B. J. Gormus, R. H. Wolf, W. A. Andes, M. West, and R. C. Montelaro. 1986. Isolation of an HTLV-III-related retrovirus from macaques with simian AIDS and its possible origin in asymptomatic mangabeys. Nature (London) 321:435-438.
29. National Institutes of Health. 1985. Guide for the care and use of laboratory animals, rev ed. Department of Health and Human Services publication no. (NIH) 85-23 National Institutes of Health, Bethesda, Md.
30. Nooij, F. J. M., J. G. Borst, G. J. E. Van Meurs, M. Jonker, and H. Balner. 1986. Differentiation antigens on rhesus monkey lymphocytes. I. Identification of T cells bearing CD3 and CD8, and of a subset of CD8-bearing cells. Eur. J. Immunol. 16:975-979.
31. Reimann, K. A., R. L. Cate, Y. Wu, L. Palmer, D. Olson, B. C. D. Waite, N. L. Lenin, and L. C. Burkly. 1995. In vivo administration of CD4-specific monoclonal antibody: effect on provirus load in rhesus monkeys chronically infected with the simian immunodeficiency virus of macaques. AIDS Res. Hum. Retroviruses 11:517-525.
32. Reimann, K. A., K. Tenner-Racz, P. Racz,D. C. Montefiori, Y. Yasutomi, W. Lin, B. J. Ransil, and N. L. Letvin. 1994. Immunopathogenic events in acute infection of rhesus monkeys with simian immunodeficiency virus of macaques. J. Virol. 68:2362-2370.
33. Reimann, K. A., B. C. D. Waite, D. E. Lee-Parritz, W. Lin, B. Uchanska-Ziegler, M. J. O'Connell, and N. L. Letvin. 1994 Use of human leukocyte-specific monoclonal antibodies for clinically immunophenotyping lymphocytes of rhesus monkeys. Cytometry 17:102-108.
34. Rho, H., B. Poiesz, F. Ruscetti, and R. C. Gallo. 1981. Characterization of the reverse transcriptase from a new retrovirus (HTLV) produced by a human cutaneous T-cell lymphoma cell line Virology 112:355-360.
35. Shaw, G. M., B. H. Hahn, S. K. Arya, J. E. Groopman, R. C. Gallo, and F. Wong-Staal. 1984 Molecular characterization of human T cell leukemia (lymphotropic) virus type III in the acquired immune deficiency syndrome. Science 226:1165-1171.
36. + T-helper cells. Am. J. Pathol. 140:15-22.
37. Sullivan, N., Y. Sun, J. Li, W. Hoffman, and J. Sodroski. 1995. Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates. J. Virol. 69:4413-4422
38. Tenner-Racz, K., P. Racz, M. Bofill, A. Schulz-Meyer, M. Dietrich, P. Kern, J. Weber, A. J. Pinching, F. Veronese-Dimarzo, M. Popovic, D. Klatzman, J. C. Gluckman, and G. Janossy. 1986. HTLV-III/LAV viral antigens in lymph nodes of homosexual men with persistent generalized lymphadenopathy and AIDS. Am. J. Pathol 123:9-15.
39. Voss, G., J. Li, K. Manson, M. Wyand, J. Sodroski, and N. L. Letvin. 1995. Human immunodeficiency virus type 1 envelope glycoprotein-specific cytotoxic T lymphocytes in simian-human immunodeficiency virus-infected rhesus monkeys. Virology 208:770-775.
40. Watanabe, M., K. A. Reimann, P. A. DeLong, T. Liu, R. A. Fisher, and N. L. Letvin. 1989. Effect of recombinant soluble CD4 in rhesus monkeys infected with simian immunodeficiency virus of macaques. Nature (London) 337:267-270.