Cervicovaginal human immunodeficiency virus secretion and plasma viral load in human immunodeficiency virus-seropositive women

Obstetrics and Gynecology

Volumn 90, Issue 5, 1997, Pages 739-743

  Uvin, Susan Cu ^a   Callendo, Angela M ^b  

^a MIRIAM HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RNA;

ADULT; ARTICLE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LAVAGE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; UTERINE CERVIX; VAGINA; VIRUS DETECTION; VIRUS EXCRETION; VIRUS TITRATION;

ADULT; ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; CERVIX UTERI; FEMALE; HIV INFECTIONS; HIV SEROPOSITIVITY; HIV-1; HUMANS; IRRIGATION; RNA, VIRAL; VAGINA; VIRAL LOAD;

EID: 0030855865     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0029-7844(97)00411-0     Document Type: Article

References (20)

1. Global Programs on AIDS. Current and future dimensions of HIV/AIDS pandemic. A capsule summary. Geneva, Switzerland: World Health Organization, 1992.
2. Centers for Disease Control. National HIV serosurveillance summary: Results through 1992. Vol. 3. Atlanta: U.S. Department of Health and Human Services, 1994.
3. Centers for Disease Control and Prevention. AIDS in women. U.S. 1994. MMWR 1995;44:81-4.
4. Vogt MW, Witt DJ, Craven D, Byington R, Crawford PF, Hutchinson M, et al. Isolation of HTLV-III/LAV from cervical secretions of women at risk for AIDS. Lancet 1986;1:525-7.
5. Vogt MW, Witt DJ, Craven D, Byington R, Crawford PF, Hutchinson M, et al. Isolation patterns of HIV from cervical secretions during the menstrual cycle of women at risk for AIDS. Ann Intern Med 1987;106:380-2.
6. Clementson DB, Moss GB, Willerford DM, Hensel M, Emoneji W, Holmes K, et al. Detection of HIV DNA in cervical and vaginal secretions: Prevalence and correlates among women in Nairobi, Kenya. JAMA 1993;269:2860-4.
7. Kreiss JK, Coombs R, Plummer F, Holmes K, Bevely N, Cameron N, et al. Isolation of human immunodeficiency virus from genital ulcers in Nairobi prostitutes. J Infect Dis 1989;160:380-4.
8. Wofsy CB, Cohen JB, Hauer LB, Padian NS, Michaelis BA, Evans LA, et al. Isolation of AIDS-associated retroviruses from genital secretions of women with antibodies to the virus. Lancet 1986;1: 527-9.
9. Goulston C, Stevens E, Gallo D, Mullins JI, Hanson C, Katzenstein D. Human immunodeficiency virus in plasma and genital secretions during the menstrual cycle. J Infect Dis 1996;174:858-61.
10. Henin Y, Mandelbrot L, Henrion R, Pradinaud R, Coulaud JP, Montagnier L. Virus excretion on cervicovaginal secretions of pregnant and non-pregnant HIV-infected women. J Acquir Immune Defic Syndr 1993;6:72-5.
11. Kreiss JK, Willerford DM, Hensel M, Emonyi W, Plummer F, Ndinya-Achola J, et al. Association between cervical inflammation and cervical shedding of HIV DNA, J Infect Dis 1994;170:1597-601.
12. Boom R, Sol CJ, Salimans MM, Jansen CL, Wertheim-van Dillen PM, van der Noordaa J. Rapid and simple method for purification of nucleic acids. J Clin Microbiol 1990;28:495-503.
13. Van Gemen B, Kievits T, Nara P, Huisman HG, Jurriaans S, Goudsmit J, et al. Qualitative and quantitative detection of HIV-1 RNA by nucleic acid sequence based amplification. AIDS 1993; 7(Suppl 2):S107-10.
14. Van Gemen B, Van Beuningen R, Nabbe A, van Strijp D, Jurriaans S, Lens P, et al. A one-tube quantitative HIV-1 RNA NASBA nucleic acid amplification assay using electrochemiluminescent (ECL) labelled probes. J Virol Methods 1994;49:157-67.
15. Saag MS, Crain MJ, Decker WD, Campbell-Hill S, Robinson S, Brown WE, et al. High level viremia in adults and children infected with human immunodeficiency virus: Relation to disease stage and CD4 lymphocyte levels. J Infect Dis 1991;164:72-80.
16. European Study Group on Heterosexual Transmission of HIV. Comparison of female to male and male to female transmission of HIV-1 in 563 stable couples. BMJ 1992;304:809-13.
17. Dickover RE, Garratty EM, Herman SA, Sim MS, Plaeger S, Boyer PJ, et al. Identification of levels of maternal HIV-1 RNA associated with risk of perinatal transmission: Effect of maternal zidovudine on viral load. JAMA 1996;275:599-605.
18. Anderson DJ, O'Brien TR, Politch JA, Martinez A, Seage GR, Padian N, et al. Effects of disease stage and zidovudine therapy on the detection of human immunodeficiency virus type-1 in semen. JAMA 1992;267:2769-74.
19. Rasheed S, Li Z, Xu D, Kovacs A. Presence of cell-free human immunodeficiency virus in cervicovaginal secretions is independent of viral load in the blood of human immunodeficiency virus-infected women. Am J Obstet Gynecol 1996;175:122-30.
20. John CC, Irduati RW, Mbori-Ngacha D, Overbaugh J, Welch M, Richardson BA, et al. Genital shedding of human immunodeficiency virus type 1 DNA during pregnancy: Association with immunosuppression, abnormal cervical or vaginal discharge, and severe vitamin A deficiency. J Infect Dis 1997;174:57-62.