Mice and humans: Chromosome engineering and its application to functional genomics

Acta Biochimica Polonica

Volumn 49, Issue 3, 2002, Pages 553-569

  Klysik, Jan ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Chromosome engineering; Embryonic stem cell technology; ENU mutagenesis; Gene traps; Transgenesis

Indexed keywords

MAMMALIA;

EID: 0037848868     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.2002_3766     Document Type: Review

References (93)

1. Allen ND, et al. (1988) Transgenes as probes for active chromosomal domains in mouse development. Nature.; 333: 852-5.
2. Baribault H, Kemler R. (1989) Embryonic stem cell culture and gene targeting in transgenic mice. Mol Biol Med.; 6: 481-92.
3. Baum L, et al. (2000) Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology Microsc Res Tech.; 50: 278-81.
4. Beddington RSP. (1992) Transgenic strategies in mouse embryology and development. In Transgenic animals. Grosveld FG, Kollias G. eds, pp 79-98. Academic Press, San Diego.
5. Bottinger EP, Kopp JB. (1998) Lessons from TGF-beta transgenic mice. Miner Electrolyte Metab.; 24: 154-60.
6. Brandon EP, Idzerda RL, McKnight GS. (1995a) Knockouts. Targeting the mouse genome: a compendium of knockouts (Part I). Curr Biol.; 5: 625-34.
7. Brandon EP, Idzerda RL, McKnight GS. (1995b) Targeting the mouse genome: a compendium of knockouts (Part II) Curr Biol.; 5: 758-65.
8. Brandon EP, Idzerda RL, McKnight GS. (1995c) Targeting the mouse genome: a compendium of knockouts (Part III). Curr Biol.; 5: 873-81.
9. Brayton C, Justice M, Montgomery CA. (2001) Evaluating mutant mice: anatomic pathology. Vet Pathol.; 38: 1-19.
10. Brennan J, Skarnes WC. (1999) Gene trapping in mouse embryonic stem cells. Methods Mol Biol.; 97: 123-38.
11. Brinster RL. (1974) The effect of cells transferred into the mouse blastocyst on subsequent development. J Exp Med.; 140: 1049-56.
12. Brown SD, Nolan PM. (1998) Mouse mutagenesis-systematic studies of mammalian gene function. Hum Mol Genet.; 7: 1627-33.
13. Brusa R. (1999) Genetically modified mice in neuropharmacology. Pharmacol Res.; 39: 405-19.
14. Capecchi MR. (1989) Altering the genome by homologous recombination. Science.; 244: 1288-92.
15. Carter TC. (1951) Wavy-coated mice: phenotypic interactions and linkage tests between rex and (a) waved-1, (b) waved-2. J Genet.; 50: 268-76.
16. Cecconi F, Meyer BI. (2000) Gene trap: a way to identify novel genes and unravel their biological function. FEBS Lett.; 480: 63-71.
17. Chen Z, Friedrich GA, Soriano P. (1994) Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice. Genes Dev.; 8: 2293-301.
18. Chowdhury K, et al. (1997) Evidence for the stochastic integration of gene trap vectors into the mouse germline Nucleic Acids Res.; 25: 1531-6.
19. Clarke AR. (2000) Manipulating the germline: its impact on the study of carcinogenesis. Carcinogenesis.; 21: 435-41.
20. Crew FAE, Auerbach C. (1939) Rex: a dominant autosomal monogenic coat texture character in the mouse. J Genet.; 38: 341-4.
21. El-Sohemy A, Archer MC. (1999) Regulation of mevalonate synthesis in low density lipoprotein receptor knockout mice fed n-3 or n-6 polyunsaturated fatty acids. Lipids.; 34: 1037-43.
22. Evans MJ, Kaufman MH. (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature.; 292: 154-6.
23. Friedrich G, Soriano P. (1991) Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev.; 5: 1513-23.
24. Gu H, et al. (1994) Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science.; 265: 103-6.
25. Hadjantonakis AK, Nagy A. (2001) The color of mice: in the light of GFP-variant reporters. Histochem Cell Biol.; 115: 49-58.
26. Hadjantonakis AK, et al. (1998) Generating green fluorescent mice by germline transmission of green fluorescent ES cells. Mech Dev.; 76: 79-90.
27. Hanahan D. (1989) Transgenic mice as probes into complex systems. Science.; 246: 1265-75.
28. Hidaka M, et al. (2000) Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells. Mech Dev.; 90: 3-15.
29. Hitotsumachi S, Carpenter DA, Russell WL. (1985) Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia. Proc Natl Acad Sci U S A.; 82: 6619-21.
30. Holschneider DP, Shih JC. (2000) Genotype to phenotype: challenges and opportunities. Int J Dev Neurosci.; 18: 615-8.
31. Hong HK, et al. (2001) The winged heix/forkhead transcription factor Foxq1 regulates differentiation of hair in satin mice. Genesis.; 29: 163-71.
32. Ihle JN. (2000) The challenges of translating knockout phenotypes into gene function. Cell.; 102: 131-4.
33. Jaenisch R. (1976) Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus. Proc Natl Acad Sci U S A.; 73: 1260-4.
34. Justice MJ, Bode VC. (1988) Three ENU-induced alleles of the murine quaking locus are recessive embryonic lethal mutations. Genet Res.; 51: 95-102.
35. Justice MJ, Zheng B, Bradley A. (1997) Using targeted large deletions and high-efficiency N-ethyl-N-nitrosourea mutagenesis for functional analyses of the mammalian genome. Methods.; 13: 423-36.
36. Kaminski N. (2000) Bioinformatics A user's perspective. Am J Respir Cell Mol Biol.; 23: 705-11.
37. Klysik J, et al. (1999) An integrated gene and SSLP BAC map framework of mouse chromosome 11 Genomics.; 62: 123-8.
38. Klysik J. (2001) Concept of immunomics: a new frontier in the battle for gene function? Acta Biotheor.; 49: 191-202.
39. Klysik J, Justice M, Bradley A. (2002) Chromosome engineering and ENU mutagenesis: their use for defining gene function. Curr Genomics.; (in press).
40. Kollias F, Grosveld FG. (1992) Transgenic strategies in mouse embryology and development. In Transgenic Animals. Grosveld FG, Kollias G. eds, pp 47-77. Academic Press, San Diego.
41. Kothary R, et al. (1988) A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube. Nature.; 335: 435-7.
42. Lander ES, et al. (2001) Initial sequencing and analysis of the human genome. Nature.; 409: 860-921.
43. Lewandoski M. (2001) Conditional control of gene expression in the mouse. Nat Rev Genet.; 2: 743-55.
44. Lindsay EA, et al. (1999) Congenital heart disease in mice deficient for the DiGeorge syndrome region. Nature.; 401: 379-83.
45. Lindsay EA, et al. (2001) Tbx1 haploinsufficiency in the DiGeorge syndrome region causes aortic arch defects in mice. Nature.; 410: 97-101.
46. Lyon MF, Phillips RJ, Fisher G. (1982) Use of an inversion to test for induced X-linked lethals in mice. Mutat Res.; 92: 217-28.
47. Martin GR. (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A.; 78: 7634-8.
48. McClatchey AI, Jacks T. (1998) Tumor suppressor mutations in mice: the next generation. Curr Opin Genet Dev.; 8: 304-10.
49. Merscher S, et al. (2001) TBX1 is responsible for cardiovascular defects in velo-cardio-facial/ DiGeorge syndrome. Cell.; 104: 619-29.
50. Miklos GL, Rubin GM. (1996) The role of the genome project in determining gene function: insights from model organisms. Cell.; 86: 521-9.
51. Minabe-Saegusa C, et al. (1998) Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach. Dev Growth Differ.; 40: 343-53.
52. Mintz B, Cronmiller C. (1978) Normal blood cells of anemic genotype in teratocarcinoma-derived mosaic mice. Proc Natl Acad Sci U S A.; 75: 6247-51.
53. Moore KJ. (1999) Utilization of mouse models in the discovery of human disease genes. Drug Discov Today.; 4: 123-8.
54. Muller HJ. (1918) Genetic variability, twin hybrids and constant hybrids, in a case of balanced lethal factors. Genetics.; 3: 422-99.
55. Nolan PM, et al. (2000) Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource. Mamm Genome.; 11: 500-6.
56. Noveroske JK, Weber JS, Justice MJ. (2000) The mutagenic action of N-ethyl-N-nitrosourea in tne mouse. Mamm Genome.; 11: 478-83.
57. Palapattu GS, et al. (1998) Transgenic mouse models for tumor suppressor genes. Cancer Detect Prev.; 22: 75-86.
58. Palmiter RD, Brinster RL. (1986) Germ-line transformation of mice. Annu Rev Genet.; 20: 465-99.
59. Papaioannou VE, et al. (1975) Fate of teratocarcinoma cells injected into early mouse embryos. Nature.; 258: 70-3.
60. Pennisi E. (2000) Human genome. Finally, the book of life and instructions for navigating it. Science.; 288: 2304-7.
61. Pirity M, Hadjantonakis AK, Nagy A. (1998) Embryonic stem cells, creating transgenic animals. Methods Cell Biol.; 57: 279-93.
62. Pitot HC, et al. (2000) Review article: the stages of gastrointestinal carcinogenesis - application of rodent models to human disease. Aliment Pharmacol Ther.; 14: (Suppl 1) 153-60.
63. Postic C, et al. (1999) Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic β cell-specific gene knock-outs using Cre recombinase. J Biol Chem.; 274: 305-15.
64. Ramirez-Solis R, Liu P, Bradley A. (1995) Chromosome engineering in mice. Nature.; 378: 720-4.
65. Rathkolb B, et al. (2000) Large-scale N-Ethyl-N-nitrosourea mutagenesis of mice - from phenotypes to genes. Exp Physiol.; 85: 635-44.
66. Rinchik EM. (1991) Chemical mutagenesis and fine-structure functional analysis of the mouse genome. Trends Genet.; 7: 15-21.
67. Rinchik EM. (2000) Developing genetic reagents to facilitate recovery, analysis, and maintenance of mouse mutations. Mamm Genome.; 11: 345-51.
68. Rinchik EM, Carpenter DA. (1999) N-ethyl-N-nitrosourea mutagenesis of a 6- to 11-cM subregion of the Fah-Hbb interval of mouse chromosome 7: Completed testing of 4557 gametes and deletion mapping and complementation analysis of 31 mutations. Genetics.; 152: 373-83.
69. Rinchik EM, Carpenter DA, Selby PB. (1990) A strategy for fine-structure functional analysis of a 6- to 11-centimorgan region of mouse chromosome 7 by high-efficiency mutagenesis. Proc Natl Acad Sci U S A.; 87: 896-900.
70. Robertson EJ. (1987) Embryo-derived stem cell lines. In Teratocarcinomas and embryonic stem cells: a practical approach. Robertson EJ. ed, pp 71-112. IRL Press, Oxford.
71. Rogers J, Bradley A. (2001) The mouse genome sequence: status and prospects. Genomics.; 77: 117-8.
72. Ross AJ, et al. (1998) Testicular degeneration in Bclw-deficient mice. Nat Genet.; 18: 251-6.
73. Sam M, et al. (1998) Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif. Dev Dyn.; 212: 304-17.
74. Shedlovsky A, et al. (1993) Mouse models of human phenylketonuria. Genetics.; 134: 1205-10.
75. Shedlovsky A, King TR, Dove WF. (1988) Saturation germ line mutagenesis of the murine t region including a lethal allele at the quaking locus. Proc Natl Acad Sci U S A.; 85: 180-4.
76. Shibuya T, Morimoto K. (1993) A review of the genotoxicity of 1-ethyl-1-nitrosourea. Mutat Res.; 297: 3-38.
77. Sidman RL, Dicke MM, Appel SH. (1964) Mutant mice (quaking and jimpy) with deficient myelination in the central nervous system. Science.; 144: 309-11.
78. Si-Hoe SL, Wells S, Murphy D. (2001) Production of transgenic rodents by the microinjection of cloned DNA into fertilized one-cell eggs. Mol Biotechnol.; 17: 151-82.
79. Skarnes WC, et al. (1995) Capturing genes encoding membrane and secreted proteins important for mouse development. Proc Natl Acad Sci U S A.; 92: 6592-6.
80. Smith AG, et al. (1988) Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature.; 336: 688-90.
81. Soewarto D, et al. (2000) The large-scale Munich ENU-mouse-mutagenesis screen. Mamm Genome.; 11: 507-10.
82. Sreekumar KR, Aravind L, Koonin EV. (2001) Computational analysis of human disease-associated genes and their protein products. Curr Opin Genet Dev.; 11: 247-57.
83. Takeuchi T, et al. (1995) Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation. Genes Dev.; 9: 1211-22.
84. Thorey IS, et al. (1998) Selective disruption of genes transiently induced in differentiating mouse embryonic stem cells by using gene trap mutagenesis and site-specific recombination. Mol Cell Biol.; 18: 3081-8.
85. Tsai TF, et al. (1999) Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome. Hum Mol Genet.; 8: 1357-64.
86. Tsoka S, Ouzounis CA. (2000) Recent developments and future directions in computational genomics. FEBS Lett.; 480: 42-8.
87. Venter JC, et al. (2001) The sequence of the human genome. Science.; 291: 1304-51.
88. Wobus AM, et al. (1984) Characterization of a pluripotent stem cell line derived from a mouse embryo. Exp Cell Res.; 152: 212-9.
89. Woychik RP, Alagramam K. (1998) Insertional mutagenesis in transgenic mice generated by the pronuclear microinjection procedure. Int J Dev Biol.; 42: 1009-17.
90. Zambrowicz BP, Friedrich GA. (1998) Comprehensive mammalian genetics: history and future prospects of gene trapping in the mouse. Int J Dev Biol.; 42: 1025-36.
91. Zheng B, Mills AA, Bradley A. (1999) A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice. Nucleic Acids Res.; 27: 2354-60.
92. Zheng B, Mills AA, Bradley A. (2001) Introducing defined chromosomal rearrangements into the mouse genome. Methods.; 24: 81-94.
93. Zheng B, et al. (1999) Engineering a mouse balancer chromosome. Nat Genet.; 22: 375-8.