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The report of the human genome sequence from the private company Celera Genomics. In the preliminary analysis of the predicted human proteome, molecular functions for ˜60% of the proteins have been assigned by automatic means utilizing the protein family databases such as Pfam and SMART. The authors have also identified a partial set of human-fly and human-worm orthologs. A preliminary survey of the differences between the human genome and other sequenced eukaryotic genomes is also presented
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Experimental validation of the role of frataxin in mitochondrial energy conversion that corroborates with the computational prediction
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