Antibacterial properties of the sperm-binding proteins and peptides of human epididymis 2 (HE2) family; salt sensitivity, structural dependence and their interaction with outer and cytoplasmic membranes of Escherichia coli

Biochemical Journal

Volumn 372, Issue 2, 2003, Pages 473-483

  Yenugu, Suresh ^a   Hamil, Katherine G ^a   Birse, Charles E ^b   Ruben, Steven M ^b   French, Frank S ^a   Hall, Susan H ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

Antibacterial activity; Defensin; Fertility; Host defence; Human epididymis 2 (HE2); Sperm binding protein

Indexed keywords

BIOLOGICAL MEMBRANES; CHEMICAL BONDS; ESCHERICHIA COLI; NITROGEN COMPOUNDS; SODIUM CHLORIDE;

SPERM-BINDING PROTEINS;

PROTEINS;

BETA DEFENSIN; BINDING PROTEIN; DISULFIDE; HUMAN EPIDIDYMIS 2ALPHA; HUMAN EPIDIDYMIS 2BETA1; HUMAN EPIDIDYMIS 2BETA2; LIPOCALIN; RECOMBINANT PROTEIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL PERMEABILIZATION; COLONY FORMING UNIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISULFIDE BOND; DRUG MECHANISM; DRUG POTENCY; ERYTHROCYTE; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE SEQUENCE; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; REDUCTION; SPERM; TIME;

ALKYLATION; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTIGENS, SURFACE; BETA-DEFENSINS; CARRIER PROTEINS; CELL MEMBRANE PERMEABILITY; COLONY COUNT, MICROBIAL; CYSTEINE PROTEINASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDIDYMIS; ESCHERICHIA COLI; GLYCOPEPTIDES; HUMANS; MALE; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; SEMEN; SEMINAL PLASMA PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM CHLORIDE; SPERMATOZOA;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0037662757     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030225     Document Type: Article

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