Organization of the human gene encoding the epididymis-specific EP2 protein variants and its relationship to defensin genes

Biology of Reproduction

Volumn 64, Issue 4, 2001, Pages 1072-1079

  Frohlich O ^a   Po, C ^a   Young, L G ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gene regulation; Male reproductive tract; Sperm maturation; Testosterone

Indexed keywords

DEFENSIN; GENE PRODUCT; PROTEIN EP2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMOSOME 8P; EPIDIDYMIS; EXON; GENE EXPRESSION; GENE STRUCTURE; GENETIC VARIABILITY; INTRON; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SPERMATOZOON MATURATION; TISSUE SPECIFICITY;

EID: 0035085456     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod64.4.1072     Document Type: Article

References (33)

1. Alterations in primate sperm motility with maturation and during exposure to theophylline
2. Epididymal maturation and the acrosome reaction in mouse sperm: Response to zona pellucida develops coincident with modification of M42 antigen
3. FLB1, a human protein of epididymal origin that is involved in the sperm-oocyte recognition process
4. On the epididymis and its role in the development of the fertile ejaculate
5. Sperm surface components involved in the control of the acrosome reaction
6. Inconsistent reactivity of an anti-sperm monoclonal antibody and its relationship to sperm capacitation
7. Studies on sperm capacitation using monoclonal antibody - Disappearance of an antigen from the anterior part of mouse sperm head
8. Competition between zonae pellucidae and a proteinase inhibitor for sperm binding
9. Characterization of low Mr zona pellucida binding proteins from boar spermatozoa and seminal plasma
10. Specialized gene expression in the epididymis
11. Function of human epididymal proteins in sperm maturation
12. Androgens and epididymal function
13. Multiple promoter and splicing mRNA variants of the epididymis-specific gene EP2
14. HE2beta and HE2gamma, new members of an epididymis-specific family of androgen-regulated proteins in the human
15. Cloning and analysis of mRNAs expressed specifically in the human epididymis
16. Molecular cloning and characterization of a novel human sperm antigen (HE2) specifically expressed in the proximal epididymis
17. Defensins and other endogenous peptide antibiotics of vertebrates
18. The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: Two peptide families with differing disulfide topology share a common ancestry
19. Solution structure of bovine neutrophil beta-defensin-12: The peptide fold of the beta-defensins is identical to that of the classical defensins
20. Beta-defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6
21. hBD-1: A novel beta-defensin from human plasma
22. A peptide antibiotic from human skin
23. Mapping of the gene encoding human beta-defensin-2 (DEFB2) to chromosome region 8p22-p231
24. A 450-kb contig of defensin genes on human chromosome 8p23
25. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli
26. HE2/EP2, an androgen-dependent protein from the epididymis of the chimpanzee, Pan troglodytes
27. A consensus DNA-binding site for the androgen receptor
28. Extensive nuclear DNA sequence diversity among chimpanzees
29. Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-1 (CRISP-1) gene
30. The PEA3 protein of the Ets oncogene family is a putative transcriptional modulator of the mouse epididymis-specific glutathione peroxidase gene gpx5
31. Involvement of polyomavirus enhancer activator 3 in the regulation of expression of gamma-glutamyl transpeptidase messenger ribonucleic acid-IV in the rat epididymis
32. Intramolecular inhibition of human defensin HNP-1 by its propiece