Engineered salt-insensitive α-defensins with end-to-end circularized structures

Journal of Biological Chemistry

Volumn 275, Issue 6, 2000, Pages 3943-3949

  Yu, Qitao ^a   Lehrer, Robert I ^b   Tam, James P ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEFENSIN;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CHEMICAL BOND; CYCLIZATION; DRUG SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

ALPHA-DEFENSINS; AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; DEFENSINS; DISULFIDES; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PROTEIN ENGINEERING; PROTEINS; RABBITS; SALMONELLA TYPHIMURIUM; SALTS; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; ORYCTOLAGUS CUNICULUS; SALMONELLA TYPHIMURIUM; THIA; TYPHIMURIUM;

EID: 0034635459     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.6.3943     Document Type: Article

References (57)

1. Ganz, T., and Lehrer, R. I. (1998) Curr. Opin. Immunol. 10, 41-44
2. Hancock, R. E., and Lehrer, R. (1998) Trends Biotechnol. 16, 82-88
3. Meister, M., Lemaitre, B., and Hoffmann, J. A (1997) BioEssays 19, 1019-1026
4. Ouellette, A. J., and Selsted, M. E. (1996) FASEB J. 10, 1280-1289
5. Nicolas, P., and Mor, A. (1995) Annu. Rev. Microbiol. 49, 277-304
6. Porter, E. M., Liu, L., Oren, A., Anton, P. A., and Ganz, T. (1997) Inf. Immun. 65, 2389-2395
7. Porter, E. M., van Dam, E., Valore, E. V., and Ganz, T. (1997) Inf. Immun. 65, 2396-2401
8. Charlet, M., Chernysh, S., Philippe, H., Hetru, C., Hoffmann, J. A., and Bulet, P. (1996) J. Biol. Chem. 271, 21808-21813
9. Selsted, M. E., Miller, S. I. Henschen, A. H., and Ouellette, A. J. (1992) J. Cell Biol. 118, 929-936
10. Valore, E. V., Park, C. H., Quayle, A. J., Wiles, K. R., McCray, P. B., Jr., and Ganz, T. (1998) J. Clin. Invest. 101, 1633-1642
11. Terras, F. R. G., Eggermont, K., Kovaleva, V., Raikhel, N. V., Osborn, R. W., Kester, A., Rees, S., Torrekens, S., Van Leuven, F., Vanderleyden, J., Cammue, B. P. A., and Broekaert, W. F. (1995) Plant Cell 7, 573-588
12. White, S. H., Wimley, W. C., and Selsted, M. E. (1995) Curr. Opin. Struct. Biol. 5, 521-527
13. Bals, R., Goldman, M. J., and Wilson, J. M. (1998) Infect. Immun. 66, 1225-1232
14. Goldman, M. J., Anderson, G. M., Stolzenberg, E. D., Kari, U. P., Zasloff, M., and Wilson, J. M. (1997) Cell 88, 553-560
15. Cornet, B., Bonmatin, J. M., Hetru, C., Hoffmann, J. A., Ptak, M., and Vovelle, F. (1995) Structure 3, 435-448
16. Bonmatin, J. M., Bonnat, J. L., Gallet, X., Vovelle, F., Ptak, M., Reichhart, J. M., Hoffmann, J. A., Keppi, E., Legrain, M., and Achstetter, T. (1992) J. Biomol. NMR 2, 235-256
17. Gustafson, K. R., Sowder, R. C., II, Henderson, L. E., Parsons, I. C., Kashman, Y., Cardellina, J. H., II, McMahon, J. B., Buckheit, R. W., Jr., Pannell, L. K., and Boyd, M. R. (1994) J. Am. Chem. Soc. 116, 9337-9338
18. Witherup, K. M., Bogusky, M. J., Anderson, P. S., Ramjit, H., Ransom, R. W., Wood, T., and Sardana, M. (1994) J. Nat. Prod. 57, 1619-1625
19. Gran, L. (1973) Acta Pharmacol. Toxicol. 32, 400-408
20. Saether, O., Craik, D. J., Campbell, I. D., Sletten, K., Juul, J., and Norman, D. G. (1995) Biochemistry 34, 4147-4158
21. Zhang, L., and Tam, J. P. (1997) J. Am. Chem. Soc. 119, 2363-2370
22. Hojo, H., and Aimoto, S. (1991) Bull. Chem. Soc. Jpn. 64, 111-117
23. Ellman, G. L. (1959) Arch. Biochem. Biophys. 82, 70-77
24. Merrifield, R. B. (1963) J. Am. Chem. Soc. 85, 2149-2154
25. Merrifield, R. B. (1986) Science 57, 1619-1625
26. Stewart, S. M., and Young, J. D. (1984) Solid Phase Peptide Synthesis, 2nd Ed., p. 113, Pierce Chemical Co. Press, Rockford, IL
27. Steinberg, D., and Lehrer., R. I. (1997) in Methods in Molecular Biology (Shafer, W. M., ed). pp. 169-187, Humana Press, Totowa, NJ
28. Turner, J., Cho, Y., Dinh, N., Waring, A. J., and Lehrer, R. I. (1998) Antimicrob. Agents Chemother. 42, 2206-2214
29. Cho, Y., Turner, J. S., Dinh, N., and Lehrer, R. I. (1998) Infect. Immun. 66, 2791-2797
30. Merrifield, R. B., Juvvadi, P., Andreu, D., Ubach, J., Boman, A., and Boman, H. G. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 3449-3453
31. Juvvadi, P., Vunnam, S., and Merrifield, R. B. (1996) J. Am. Chem. Soc. 118, 8989-8997
32. Christensen, B., Fink, J., Merrifield, R. B., and Mauzerall, D. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 5072-5076
33. Hill, C. P., Yee, J., Selsted, M. E., and Eisenberg D. (1991) Science 251, 1481-1485
34. Liu, C.-F., and Tam, J. P. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 6584-6588
35. Liu, C.-F., Rao, C., and Tam, J. P. (1996) J. Am. Chem. Soc. 118, 307-312
36. Botti, P., Pallin, T. D., and Tam, J. P. (1996) J. Am. Chem. Soc. 118, 10018-10024
37. Tam, J. P., Lu, Y. A., Liu, C.-F., and Shao, J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 12485-12489
38. Tam, J. P., and Yu, Q. (1998) Biopolymer 46, 319-327
39. Liu, C.-F., Rao, C., and Tam, J. P. (1996) Tetrahedron Lett. 37, 933-936
40. Xu, M.-Q., and Perler, F. B. (1996) EMBO J. 15, 5146-5153
41. Xu, M.-Q., Southworth, M. W., Mersha, F. B., Hornstra, L. J., and Perler, F. B. (1993) Cell 75, 1371-1377
42. Zhang, L., and Tam, J. P. (1997) Tetrahedron Lett. 38, 3-6
43. Lu, Y. A., and Tam, J. P. (1997) Tetrahedron Lett. 38, 5599-5602
44. Tam, J. P., Wu, C. R., Liu, W., and Zhang, J. W. (1991) J. Am. Chem. Soc. 113, 6657-6662
45. Yang, Y., Sweeney, W. W., Schneider, K., Chait, B. T., and Tam, J. P. (1994) Protein Sci. 3, 1267-1275
46. Beamer, L. J., Carroll, S. F., and Eisenberg, D. (1997) Science 276, 1861-1864
47. Fourmy, D., Recht, M. I., Blanchard, S. C., and Puglisi, J. D. (1996) Science 274, 1367-1371
48. Struthers, M. D., Cheng, R. P., and Immperiali, B. (1996) Science 271, 342-345
49. Yeh, T. M., Chao, S. C., and Chang, H. C. (1994) Chin. J. Microbiol. Immunol. 27, 120-132
50. Shimoda, M., Ohki, K., Shimamoto, Y., and Kohashi, O. (1995) Infect. Immun. 63, 2886-2891
51. Kagan, B. L., Selsted, M. E., Ganz, T., and Lehrer, R. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 210-214
52. Fahrner, R. L., Dieckmann, T., Harwig, S. S., Lehrer, R. I., Eisenberg, D., and Feigon, J. (1996) J. Chem. Biol. 3, 543-550
53. Roumestand, C., Louis, V., Aumelas, A., Grassy, G., Calas, B., and Chavanieu, A. (1998) FEBS Lett. 421, 263-267
54. Zhang, X.-L., Selsted, M. E., and Pardi, A. (1992) Biochemistry 31, 11348-11356
55. Pardi, A. Zhang, X.-L., Selsted, M. E., Skalicky, J. J., and Yip, P. F. (1991) Biochemistry 31, 11357-11364
56. Lin, Y. Z., Ke, X.-H., and Tam, J. P. (1991) Biochemistry 30, 3310-3314
57. Tang, Y.-Q, Yuan, J., Osapay, G., Osapay, K., Tran, D., Miller, C. J., Ouellette, A. J., and Selsted, M. E. (1999) Science 286, 498-502