메뉴 건너뛰기




Volumn 5, Issue 4, 2003, Pages 295-303

Molecular targets in therapy for human soft-tissue and bone sarcomas

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; APOLIPOPROTEIN; APOLIPOPROTEIN 2; CAMPTOTHECIN DERIVATIVE; CETUXIMAB; CISPLATIN; CYCLOPHOSPHAMIDE; DACARBAZINE; DNA TOPOISOMERASE INHIBITOR; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; GEFITINIB; GROWTH FACTOR; IFOSFAMIDE; IMATINIB; IRINOTECAN; LOPERAMIDE; MELPHALAN; METHOTREXATE; OBLIMERSEN; PLATELET DERIVED GROWTH FACTOR; PROTEIN BCL 2; TOPOTECAN; TRASTUZUMAB; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; VINCRISTINE;

EID: 0037658619     PISSN: 15233790     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11912-003-0069-8     Document Type: Review
Times cited : (6)

References (80)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA: The hallmarks of cancer. Cell 2000, 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 3
    • 0031865087 scopus 로고    scopus 로고
    • Results of two consecutive trials of dose-intensive chemotherapy with doxorubicin and ifosfamide in patients with sarcomas
    • Patel S, Vadhan-Raj S, Burgess M, et al.: Results of two consecutive trials of dose-intensive chemotherapy with doxorubicin and ifosfamide in patients with sarcomas. Am J Clin Oncol 1998, 21:317-321.
    • (1998) Am. J. Clin. Oncol. , vol.21 , pp. 317-321
    • Patel, S.1    Vadhan-Raj, S.2    Burgess, M.3
  • 4
    • 0030912403 scopus 로고    scopus 로고
    • High-dose ifosfamide in bone and soft-tissue sarcomas: Results of phase II and pilot studies - Dose response and schedule dependence
    • Patel S, Vadhan-Raj S, Papadopoulos N, et al.: High-dose ifosfamide in bone and soft-tissue sarcomas: results of phase II and pilot studies - dose response and schedule dependence. J Clin Oncol 1997, 15:2378-2384.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 2378-2384
    • Patel, S.1    Vadhan-Raj, S.2    Papadopoulos, N.3
  • 5
    • 0030693335 scopus 로고    scopus 로고
    • NEoadjuvant chemotherapy in malignant fibrous histiocytoma of bone and in osteosarcoma located in the extremities: Analogies and differences between the two tumors
    • Picci P, Bacci G, Ferrari S, et al.: NEoadjuvant chemotherapy in malignant fibrous histiocytoma of bone and in osteosarcoma located in the extremities: analogies and differences between the two tumors. Ann Oncol 1997, 8:1107-1115.
    • (1997) Ann. Oncol. , vol.8 , pp. 1107-1115
    • Picci, P.1    Bacci, G.2    Ferrari, S.3
  • 6
    • 0037103424 scopus 로고    scopus 로고
    • Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
    • Demetri GD, von Mehren M, Blanke CD, et al.: Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 2002, 347:472-480.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 472-480
    • Demetri, G.D.1    von Mehren, M.2    Blanke, C.D.3
  • 7
    • 0032793878 scopus 로고    scopus 로고
    • Molecular pathology of soft tissue and bone tumors: A review
    • Slominski A, Wortsman J, Carlson A, et al.: Molecular pathology of soft tissue and bone tumors: a review. Arch Pathol Lab Med 1999, 123:1246-1259.
    • (1999) Arch. Pathol. Lab. Med. , vol.123 , pp. 1246-1259
    • Slominski, A.1    Wortsman, J.2    Carlson, A.3
  • 8
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J: Cell signaling by receptor tyrosine kinases. Cell 2000, 103:211-225.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 9
    • 0016709236 scopus 로고
    • Adriamycin (NSC-123-127) used alone and in combination for soft tissue and bony sarcomas
    • Gottlieb J, Baker L, O'Bryan R, et al.: Adriamycin (NSC-123-127) used alone and in combination for soft tissue and bony sarcomas. Cancer Chemother Rep 1974, 6:271-282.
    • (1974) Cancer Chemother. Rep. , vol.6 , pp. 271-282
    • Gottlieb, J.1    Baker, L.2    O'Bryan, R.3
  • 10
    • 0003222972 scopus 로고    scopus 로고
    • High incidence of durable responses induced by imatinib mesylate (Gleevec) in patients with unresectable and metastatic gastrointestinal stromal tumors (GISTs)
    • [abstract]
    • von Mehren M, Blanke C, Joensuu H, et al.: High incidence of durable responses induced by imatinib mesylate (Gleevec) in patients with unresectable and metastatic gastrointestinal stromal tumors (GISTs) [abstract]. Proc ASCO 2002, 21:1608.
    • (2002) Proc. ASCO , vol.21 , pp. 1608
    • von Mehren, M.1    Blanke, C.2    Joensuu, H.3
  • 11
    • 0035810148 scopus 로고    scopus 로고
    • Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
    • Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al.: Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 2001, 344:1052-1056.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1052-1056
    • Joensuu, H.1    Roberts, P.J.2    Sarlomo-Rikala, M.3
  • 12
    • 0026572264 scopus 로고
    • Differential migratory response of U-2 OS osteosarcoma cell to the various forms of platelet-derived growth factor
    • Allam M, Martinet N, Martinet Y: Differential migratory response of U-2 OS osteosarcoma cell to the various forms of platelet-derived growth factor. Biochimie 1992, 74:183-186.
    • (1992) Biochimie , vol.74 , pp. 183-186
    • Allam, M.1    Martinet, N.2    Martinet, Y.3
  • 13
    • 0031685582 scopus 로고    scopus 로고
    • Neurofibrosarcoma-derived Schwann cells overexpress platelet-derived growth factor (PDGF) receptors and are induced to proliferate by PDGF BB
    • Badache A, De Vries GH: Neurofibrosarcoma-derived Schwann cells overexpress platelet-derived growth factor (PDGF) receptors and are induced to proliferate by PDGF BB. J Cell Physiol 1998, 177:334-342.
    • (1998) J. Cell Physiol. , vol.177 , pp. 334-342
    • Badache, A.1    De Vries, G.H.2
  • 14
    • 0024446720 scopus 로고
    • Expression of c-sis and other cellular proto-oncogenes in human sarcoma cell lines and biopsies
    • Fahrer C, Brachmann R, von der Helm K: Expression of c-sis and other cellular proto-oncogenes in human sarcoma cell lines and biopsies. Int J Cancer 1989, 44:652-657.
    • (1989) Int. J. Cancer , vol.44 , pp. 652-657
    • Fahrer, C.1    Brachmann, R.2    von der Helm, K.3
  • 15
    • 0344097469 scopus 로고    scopus 로고
    • A case of dermatofibrosarcoma protuberans with a ring chromosome 5 and a rearranged chromosome 22 containing amplified COL1A1 and PDGFB sequences
    • Gisselsson D, Hoglund M, O'Brien KP, et al.: A case of dermatofibrosarcoma protuberans with a ring chromosome 5 and a rearranged chromosome 22 containing amplified COL1A1 and PDGFB sequences. Cancer Lett 1998, 133:129-134.
    • (1998) Cancer Lett. , vol.133 , pp. 129-134
    • Gisselsson, D.1    Hoglund, M.2    O'Brien, K.P.3
  • 16
    • 0027313497 scopus 로고
    • Platelet derived growth factor/tyrosine kinase receptor mediated proliferation
    • Benito M, Lorenzo M: Platelet derived growth factor/tyrosine kinase receptor mediated proliferation. Growth Regul 1993, 3:172-179.
    • (1993) Growth Regul. , vol.3 , pp. 172-179
    • Benito, M.1    Lorenzo, M.2
  • 17
    • 0025055311 scopus 로고
    • Cultured Kaposi's sarcoma-derived cells express functional PDGF A-type and B-type receptors
    • Werner S, Hofschneider PH, Heldin CH, et al.: Cultured Kaposi's sarcoma-derived cells express functional PDGF A-type and B-type receptors. Exp Cell Res 1990, 187:98-103.
    • (1990) Exp. Cell Res. , vol.187 , pp. 98-103
    • Werner, S.1    Hofschneider, P.H.2    Heldin, C.H.3
  • 18
    • 0021266088 scopus 로고
    • Transformation of NIH 3T3 cells by a human c-sis cDNA clone
    • Clarke MF, Westin E, Schmidt D, et al.: Transformation of NIH 3T3 cells by a human c-sis cDNA clone. Nature 1984, 308:464-467.
    • (1984) Nature , vol.308 , pp. 464-467
    • Clarke, M.F.1    Westin, E.2    Schmidt, D.3
  • 19
    • 0021678482 scopus 로고
    • Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: Implications for autocrine receptor activation
    • Betsholtz C, Westermark B, Ek B, et al.: Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: implications for autocrine receptor activation. Cell 1984, 39:447-457.
    • (1984) Cell , vol.39 , pp. 447-457
    • Betsholtz, C.1    Westermark, B.2    Ek, B.3
  • 20
    • 0024259065 scopus 로고
    • Different effects of homo- and heterodimers of platelet-derived growth factor A and B chains on human and mouse fibroblasts
    • Kazlauskas A, Bowen-Pope D, Seifert R, et al.: Different effects of homo- and heterodimers of platelet-derived growth factor A and B chains on human and mouse fibroblasts. Embo J 1988, 7:3727-3735.
    • (1988) Embo. J. , vol.7 , pp. 3727-3735
    • Kazlauskas, A.1    Bowen-Pope, D.2    Seifert, R.3
  • 21
    • 0022336238 scopus 로고
    • The PDGF-inducible 'competence genes': Intracellular mediators of the mitogenic response
    • Callahan M, Cochran BH, Stiles CD: The PDGF-inducible 'competence genes': intracellular mediators of the mitogenic response. Ciba Found Symp 1985, 116:87-97.
    • (1985) Ciba Found. Symp. , vol.116 , pp. 87-97
    • Callahan, M.1    Cochran, B.H.2    Stiles, C.D.3
  • 22
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin CH, Westermark B: Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 1999, 79:1283-1316.
    • (1999) Physiol. Rev. , vol.79 , pp. 1283-1316
    • Heldin, C.H.1    Westermark, B.2
  • 23
    • 0031661840 scopus 로고    scopus 로고
    • Various regions within the alpha-helical domain of the COL1A1 gene are fused to the second exon of the PDGFB gene in dermatofibrosarcomas and giant-cell fibroblastomas
    • O'Brien KP, Seroussi E, Dal Cin P, et al.: Various regions within the alpha-helical domain of the COL1A1 gene are fused to the second exon of the PDGFB gene in dermatofibrosarcomas and giant-cell fibroblastomas. Genes Chromosomes Cancer 1998, 23:187-193.
    • (1998) Genes Chromosomes Cancer , vol.23 , pp. 187-193
    • O'Brien, K.P.1    Seroussi, E.2    Dal Cin, P.3
  • 24
    • 0035421175 scopus 로고    scopus 로고
    • Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis
    • Sjoblom T, Shimizu A, O'Brien KP, et al.: Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis. Cancer Res 2001, 61:5778-5783.
    • (2001) Cancer Res. , vol.61 , pp. 5778-5783
    • Sjoblom, T.1    Shimizu, A.2    O'Brien, K.P.3
  • 25
    • 0037143794 scopus 로고    scopus 로고
    • Differential sensitivity to imatinib of 2 patients with metastatic sarcoma arising from dermatofibrosarcoma protuberans
    • Maki RG, Awan RA, Dixon RH, et al.: Differential sensitivity to imatinib of 2 patients with metastatic sarcoma arising from dermatofibrosarcoma protuberans. Int J Cancer 2002, 100:623-626.
    • (2002) Int. J. Cancer , vol.100 , pp. 623-626
    • Maki, R.G.1    Awan, R.A.2    Dixon, R.H.3
  • 26
    • 0029076283 scopus 로고
    • Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor): A clinicopathologic and immunohistochemical study of 84 cases
    • Coffin CM, Watterson J, Priest JR, et al.: Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor): a clinicopathologic and immunohistochemical study of 84 cases. Am J Surg Pathol 1995, 19:859-872.
    • (1995) Am. J. Surg. Pathol. , vol.19 , pp. 859-872
    • Coffin, C.M.1    Watterson, J.2    Priest, J.R.3
  • 27
    • 0027240669 scopus 로고
    • Inflammatory myofibroblastic tumor in children
    • Souid AK, Ziemba MC, Dubansky AS, et al.: Inflammatory myofibroblastic tumor in children. Cancer 1993, 72:2042-2048.
    • (1993) Cancer , vol.72 , pp. 2042-2048
    • Souid, A.K.1    Ziemba, M.C.2    Dubansky, A.S.3
  • 28
    • 0034761584 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: A comparative immunohistochemical study
    • Cook JR, Dehner LP, Collins MH, et al.: Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical study. Am J Surg Pathol 2001, 25:1364-1371.
    • (2001) Am. J. Surg. Pathol. , vol.25 , pp. 1364-1371
    • Cook, J.R.1    Dehner, L.P.2    Collins, M.H.3
  • 29
    • 0031966587 scopus 로고    scopus 로고
    • Detection of Epstein-Barr virus in inflammatory pseudotumor
    • Arber DA, Weiss LM, Chang KL: Detection of Epstein-Barr virus in inflammatory pseudotumor. Semin Diagn Pathol 1998, 15:155-160.
    • (1998) Semin. Diagn. Pathol. , vol.15 , pp. 155-160
    • Arber, D.A.1    Weiss, L.M.2    Chang, K.L.3
  • 30
    • 0035015810 scopus 로고    scopus 로고
    • Human herpesvirus-8 genes are expressed in pulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor)
    • Gomez-Roman JJ, Sanchez-Velasco P, Ocejo-Vinyals G, et al.: Human herpesvirus-8 genes are expressed in pulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor). Am J Surg Pathol 2001, 25:624-629.
    • (2001) Am. J. Surg. Pathol. , vol.25 , pp. 624-629
    • Gomez-Roman, J.J.1    Sanchez-Velasco, P.2    Ocejo-Vinyals, G.3
  • 31
    • 0031955219 scopus 로고    scopus 로고
    • Inflammatory myofibroblastic tumor, inflammatory fibrosarcoma, and related lesions: An historical review with differential diagnostic considerations
    • Coffin CM, Dehner LP, Meis-Kindblom JM: Inflammatory myofibroblastic tumor, inflammatory fibrosarcoma, and related lesions: an historical review with differential diagnostic considerations. Semin Diagn Pathol 1998, 15:102-110.
    • (1998) Semin. Diagn. Pathol. , vol.15 , pp. 102-110
    • Coffin, C.M.1    Dehner, L.P.2    Meis-Kindblom, J.M.3
  • 32
    • 0031959425 scopus 로고    scopus 로고
    • Inflammatory myofibroblastic tumor: Cytogenetic evidence supporting clonal origin
    • Su LD, Atayde-Perez A, Sheldon S, et al.: Inflammatory myofibroblastic tumor: cytogenetic evidence supporting clonal origin. Mod Pathol 1998, 11:364-368.
    • (1998) Mod. Pathol. , vol.11 , pp. 364-368
    • Su, L.D.1    Atayde-Perez, A.2    Sheldon, S.3
  • 33
    • 0028874674 scopus 로고
    • Clonal changes in inflammatory pseudotumor of the lung: A case report
    • Snyder CS, Dell'Aquila M, Haghighi P, et al.: Clonal changes in inflammatory pseudotumor of the lung: a case report. Cancer 1995, 76:1545-1549.
    • (1995) Cancer , vol.76 , pp. 1545-1549
    • Snyder, C.S.1    Dell'Aquila, M.2    Haghighi, P.3
  • 34
    • 0033564831 scopus 로고    scopus 로고
    • Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors
    • Griffin CA, Hawkins AL, Dvorak C, et al.: Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors. Cancer Res 1999, 59:2776-2780.
    • (1999) Cancer Res. , vol.59 , pp. 2776-2780
    • Griffin, C.A.1    Hawkins, A.L.2    Dvorak, C.3
  • 35
    • 0028198206 scopus 로고
    • Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
    • Morris SW, Kirstein MN, Valentine MB, et al.: Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 1994, 263:1281-1284.
    • (1994) Science , vol.263 , pp. 1281-1284
    • Morris, S.W.1    Kirstein, M.N.2    Valentine, M.B.3
  • 36
    • 0033890820 scopus 로고    scopus 로고
    • TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors
    • Lawrence B, Perez-Atayde A, Hibbard MK, et al.: TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. Am J Pathol 2000, 157:377-384.
    • (2000) Am. J. Pathol. , vol.157 , pp. 377-384
    • Lawrence, B.1    Perez-Atayde, A.2    Hibbard, M.K.3
  • 37
    • 0033134786 scopus 로고    scopus 로고
    • A new fusion gene TPM3-ALK in anaplastic large cell lymphoma created by a (1;2)(q25;p23) translocation
    • Lamant L, Dastugue N, Pulford K, et al.: A new fusion gene TPM3-ALK in anaplastic large cell lymphoma created by a (1;2)(q25;p23) translocation. Blood 1999, 93:3088-3095.
    • (1999) Blood , vol.93 , pp. 3088-3095
    • Lamant, L.1    Dastugue, N.2    Pulford, K.3
  • 38
    • 0034989396 scopus 로고    scopus 로고
    • ALK1 and p80 expression and chromosomal rearrangements involving 2p23 in inflammatory myofibroblastic tumor
    • Coffin CM, Patel A, Perkins S, et al.: ALK1 and p80 expression and chromosomal rearrangements involving 2p23 in inflammatory myofibroblastic tumor. Mod Pathol 2001, 14:569-576.
    • (2001) Mod. Pathol. , vol.14 , pp. 569-576
    • Coffin, C.M.1    Patel, A.2    Perkins, S.3
  • 39
    • 0036134884 scopus 로고    scopus 로고
    • Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma
    • Zhang Q, Raghunath PN, Xue L, et al.: Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma. J Immunol 2002, 168:466-474.
    • (2002) J. Immunol. , vol.168 , pp. 466-474
    • Zhang, Q.1    Raghunath, P.N.2    Xue, L.3
  • 40
    • 0035871444 scopus 로고    scopus 로고
    • Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms
    • Sausville EA, Arbuck SC, Messmann R, et al.: Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms. J Clin Oncol 2001, 19:2319-2333.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 2319-2333
    • Sausville, E.A.1    Arbuck, S.C.2    Messmann, R.3
  • 41
    • 0037013154 scopus 로고    scopus 로고
    • A senescence program controlled by p53 and p16(INK4a) contributes to the outcome of cancer therapy
    • Shmitt C, Fridman J, Yang M, et al.: A senescence program controlled by p53 and p16(INK4a) contributes to the outcome of cancer therapy. Cell 2002, 109:335-346.
    • (2002) Cell , vol.109 , pp. 335-346
    • Shmitt, C.1    Fridman, J.2    Yang, M.3
  • 42
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972, 26:239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 43
    • 0033026714 scopus 로고    scopus 로고
    • Mechanisms of apoptosis avoidance in cancer
    • Reed JC: Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 1999, 11:68-75.
    • (1999) Curr. Opin. Oncol. , vol.11 , pp. 68-75
    • Reed, J.C.1
  • 44
    • 0028972616 scopus 로고
    • Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance
    • Reed JC: Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance. Curr Opin Oncol 1995, 7:541-546.
    • (1995) Curr. Opin. Oncol. , vol.7 , pp. 541-546
    • Reed, J.C.1
  • 45
    • 0034523187 scopus 로고    scopus 로고
    • Mitochondria-dependent apoptosis and cellular PH regulation
    • Matsuyama S, Reed JC: Mitochondria-dependent apoptosis and cellular PH regulation: Cell Death Differ 2000, 7:1155-1165.
    • (2000) Cell Death Differ. , vol.7 , pp. 1155-1165
    • Matsuyama, S.1    Reed, J.C.2
  • 46
    • 0035870123 scopus 로고    scopus 로고
    • Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis
    • Gao CF, Ren S, Zhang L, et al.: Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis. Exper Cell Res 2001, 265:145-151.
    • (2001) Exper. Cell Res. , vol.265 , pp. 145-151
    • Gao, C.F.1    Ren, S.2    Zhang, L.3
  • 47
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik Y: Caspases: enemies within. Science 1998, 281:1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 48
    • 0026655474 scopus 로고
    • Bcl-2 initiates a new category of oncogenes: Regulators of cell death
    • Korsmeyer SJ: Bcl-2 initiates a new category of oncogenes: regulators of cell death. Blood 1992, 80:879-886.
    • (1992) Blood , vol.80 , pp. 879-886
    • Korsmeyer, S.J.1
  • 49
    • 0031847132 scopus 로고    scopus 로고
    • Expression of bcl-2 oncoprotein in benign and malignant spindle cell tumors of soft tissue, skin, serosal surfaces, and gastrointestinal tract
    • Suster S, Fisher C, Moran CA, et al.: Expression of bcl-2 oncoprotein in benign and malignant spindle cell tumors of soft tissue, skin, serosal surfaces, and gastrointestinal tract. Am J Surg Pathol 1998, 22:863-872.
    • (1998) Am. J. Surg. Pathol. , vol.22 , pp. 863-872
    • Suster, S.1    Fisher, C.2    Moran, C.A.3
  • 50
    • 0035115145 scopus 로고    scopus 로고
    • Apoptosis, bcl-2 expression, and p53 expression in gastrointestinal stromal/smooth muscle tumors
    • Cunningham RE, Abbondanzo SL, Chu WS, et al.: Apoptosis, bcl-2 expression, and p53 expression in gastrointestinal stromal/smooth muscle tumors. Appl Immunohistochem Mol Morphol 2001, 9:19-23.
    • (2001) Appl. Immunohistochem. Mol. Morphol. , vol.9 , pp. 19-23
    • Cunningham, R.E.1    Abbondanzo, S.L.2    Chu, W.S.3
  • 51
    • 0028060247 scopus 로고
    • Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression
    • Kitada S, Takayama S, De Riel K, et al.: Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression. Antisense Res Dev 1994, 4:71-79.
    • (1994) Antisense Res. Dev. , vol.4 , pp. 71-79
    • Kitada, S.1    Takayama, S.2    De Riel, K.3
  • 52
    • 0029366403 scopus 로고
    • Antisense oligodeoxyribonucleotide down-regulation of bcl-2 gene expression inhibits growth of the low-grade non-Hodgkin's lymphoma cell line WSU-FSCCL
    • Smith MR, Abubakr Y, Mohammad R, et al.: Antisense oligodeoxyribonucleotide down-regulation of bcl-2 gene expression inhibits growth of the low-grade non-Hodgkin's lymphoma cell line WSU-FSCCL. Cancer Gene Ther 1995, 2:207-212.
    • (1995) Cancer Gene Ther. , vol.2 , pp. 207-212
    • Smith, M.R.1    Abubakr, Y.2    Mohammad, R.3
  • 53
    • 0030797704 scopus 로고    scopus 로고
    • Antisense oligonucleotide inhibitors for the treatment of cancer: 1. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides
    • Geary RS, Leeds JM, Henry SP, et al.: Antisense oligonucleotide inhibitors for the treatment of cancer: 1. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides. Anticancer Drug Des 1997, 12:383-393.
    • (1997) Anticancer Drug Des. , vol.12 , pp. 383-393
    • Geary, R.S.1    Leeds, J.M.2    Henry, S.P.3
  • 54
    • 0030888664 scopus 로고    scopus 로고
    • BCL-2 antisense therapy in patients with non-Hodgkin lymphoma
    • Webb A, Cunningham D, Cotter F, et al.: BCL-2 antisense therapy in patients with non-Hodgkin lymphoma. Lancet 1997, 349:1137-1141.
    • (1997) Lancet , vol.349 , pp. 1137-1141
    • Webb, A.1    Cunningham, D.2    Cotter, F.3
  • 55
    • 0034015672 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma
    • Waters JS, Webb A, Cunningham D, et al.: Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma. J Clin Oncol 2000, 18:1812-1823.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1812-1823
    • Waters, J.S.1    Webb, A.2    Cunningham, D.3
  • 56
    • 0031007491 scopus 로고    scopus 로고
    • Pharmacokinetics of G3139, a phosphorothioate oligodeoxynucleotide antisense to bcl-2, after intravenous administration or continuous subcutaneous infusion to mice
    • Raynaud FI, Orr RM, Goddard PM, et al.: Pharmacokinetics of G3139, a phosphorothioate oligodeoxynucleotide antisense to bcl-2, after intravenous administration or continuous subcutaneous infusion to mice. J Pharmacol Exp Ther 1997, 281:420-427.
    • (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 420-427
    • Raynaud, F.I.1    Orr, R.M.2    Goddard, P.M.3
  • 57
    • 0031907428 scopus 로고    scopus 로고
    • bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
    • Jansen B, Schlagbauer-Wadl H, Brown BD, et al.: bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat Med 1998, 4:232-234.
    • (1998) Nat. Med. , vol.4 , pp. 232-234
    • Jansen, B.1    Schlagbauer-Wadl, H.2    Brown, B.D.3
  • 58
    • 0030792712 scopus 로고    scopus 로고
    • Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
    • Sheridan JP, Marsters SA, Pitti RM, et al.: Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997, 277:818-821.
    • (1997) Science , vol.277 , pp. 818-821
    • Sheridan, J.P.1    Marsters, S.A.2    Pitti, R.M.3
  • 59
    • 0036605042 scopus 로고    scopus 로고
    • Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis
    • Evdokiou A, Bouralexis S, Atkins GJ, et al.: Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis. Int J Cancer 2002, 99:491-504.
    • (2002) Int. J. Cancer , vol.99 , pp. 491-504
    • Evdokiou, A.1    Bouralexis, S.2    Atkins, G.J.3
  • 60
    • 13144265771 scopus 로고    scopus 로고
    • A novel receptor for Apo2L/TRAIL contains a truncated death domain
    • Marsters SA, Sheridan JP, Pitti RM, et al.: A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr Biol 1997, 7:1003-1006.
    • (1997) Curr. Biol. , vol.7 , pp. 1003-1006
    • Marsters, S.A.1    Sheridan, J.P.2    Pitti, R.M.3
  • 61
    • 0000005230 scopus 로고    scopus 로고
    • Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells
    • Zhang XD, Franco AV, Nguyen T, et al.: Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells. J Immunol 2000, 164:3961-3970.
    • (2000) J. Immunol. , vol.164 , pp. 3961-3970
    • Zhang, X.D.1    Franco, A.V.2    Nguyen, T.3
  • 62
    • 0032530612 scopus 로고    scopus 로고
    • Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
    • Griffith TS, Chin WA, Jackson GC, et al.: Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J Immunol 1998, 161:2833-2840.
    • (1998) J. Immunol. , vol.161 , pp. 2833-2840
    • Griffith, T.S.1    Chin, W.A.2    Jackson, G.C.3
  • 63
    • 0032713075 scopus 로고    scopus 로고
    • Safety and antitumor activity of recombinant soluble Apo2 ligand
    • Ashkenazi A, Pai RC, Fong S, et al.: Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 1999, 104:155-162.
    • (1999) J. Clin. Invest. , vol.104 , pp. 155-162
    • Ashkenazi, A.1    Pai, R.C.2    Fong, S.3
  • 64
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M, Kim TH, Seol DW, et al.: Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 2000, 6:564-567.
    • (2000) Nat. Med. , vol.6 , pp. 564-567
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3
  • 65
    • 0035050960 scopus 로고    scopus 로고
    • Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
    • Lawrence D, Shahrokh Z, Marsters S, et al.: Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med 2001, 7:383-385.
    • (2001) Nat. Med. , vol.7 , pp. 383-385
    • Lawrence, D.1    Shahrokh, Z.2    Marsters, S.3
  • 66
    • 0035866369 scopus 로고    scopus 로고
    • Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis
    • Lacour S, Hammann A, Wotawa A, et al.: Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis. Cancer Res 2001, 61:1645-1651.
    • (2001) Cancer Res. , vol.61 , pp. 1645-1651
    • Lacour, S.1    Hammann, A.2    Wotawa, A.3
  • 67
    • 0034747649 scopus 로고    scopus 로고
    • Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin
    • Mizutani Y, Nakao M, Ogawa O, et al.: Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin. J Urol 2001, 165:263-270.
    • (2001) J. Urol. , vol.165 , pp. 263-270
    • Mizutani, Y.1    Nakao, M.2    Ogawa, O.3
  • 68
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • Loeb LA: Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 1991, 51:3075-3079.
    • (1991) Cancer Res. , vol.51 , pp. 3075-3079
    • Loeb, L.A.1
  • 69
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    • Hsiang YH, Hertzberg R, Hecht S, et al.: Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 1985, 260:14873-14878.
    • (1985) J. Biol. Chem. , vol.260 , pp. 14873-14878
    • Hsiang, Y.H.1    Hertzberg, R.2    Hecht, S.3
  • 70
    • 0015262632 scopus 로고
    • An activity from mammalian cells that untwists superhelical DNA: A possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay)
    • Champoux JJ, Dulbecco R: An activity from mammalian cells that untwists superhelical DNA: a possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay). Proc Natl Acad Sci U S A 1972, 69:143-146.
    • (1972) Proc. Natl. Acad. Sci. U. S. A. , vol.69 , pp. 143-146
    • Champoux, J.J.1    Dulbecco, R.2
  • 71
    • 0030826929 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors: Review and update
    • Rothenberg ML: Topoisomerase I inhibitors: review and update. Ann Oncol 1997, 8:837-855.
    • (1997) Ann. Oncol. , vol.8 , pp. 837-855
    • Rothenberg, M.L.1
  • 72
    • 0030014198 scopus 로고    scopus 로고
    • Experimental antitumor activity and pharmacokinetics of the camptothecin analog irinotecan (CPT-11) in mice
    • Bissery MC, Vrignaud P, Lavelle F, et al.: Experimental antitumor activity and pharmacokinetics of the camptothecin analog irinotecan (CPT-11) in mice. Anticancer Drugs 1996, 7:437-460.
    • (1996) Anticancer Drugs , vol.7 , pp. 437-460
    • Bissery, M.C.1    Vrignaud, P.2    Lavelle, F.3
  • 74
    • 0028158012 scopus 로고
    • Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks
    • Rowinsky EK, Grochow LB, Ettinger DS, et al.: Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks. Cancer Res 1994, 54:427-436.
    • (1994) Cancer Res. , vol.54 , pp. 427-436
    • Rowinsky, E.K.1    Grochow, L.B.2    Ettinger, D.S.3
  • 75
    • 0028854897 scopus 로고
    • Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients
    • Abigerges D, Chabot GG, Armand JP, et al.: Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients. J Clin Oncol 1995, 13:210-221.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 210-221
    • Abigerges, D.1    Chabot, G.G.2    Armand, J.P.3
  • 76
    • 0027933519 scopus 로고
    • Phase I and pharmacokinetic study of the camptothecin derivative irinotecan, administered on a weekly schedule in cancer patients
    • de Forni M, Bugat R, Chabot GG, et al.: Phase I and pharmacokinetic study of the camptothecin derivative irinotecan, administered on a weekly schedule in cancer patients. Cancer Res 1994, 54:4347-4354.
    • (1994) Cancer Res. , vol.54 , pp. 4347-4354
    • de Forni, M.1    Bugat, R.2    Chabot, G.G.3
  • 77
    • 0030034610 scopus 로고    scopus 로고
    • Evaluation of irinotecan in combination with 5-fluorouracil or etoposide in xenograft models of colon adenocarcinoma and rhabdomyosarcoma
    • Houghton JA, Cheshire PJ, Hallman JD II, et al.: Evaluation of irinotecan in combination with 5-fluorouracil or etoposide in xenograft models of colon adenocarcinoma and rhabdomyosarcoma. Clin Cancer Res 1996, 2:107-118.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 107-118
    • Houghton, J.A.1    Cheshire, P.J.2    Hallman II, J.D.3
  • 78
    • 0029116438 scopus 로고
    • Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors
    • Houghton PJ, Cheshire PJ, Hallman JD II, et al.: Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors. Cancer Chemother Pharmacol 1995, 36:393-403.
    • (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 393-403
    • Houghton, P.J.1    Cheshire, P.J.2    Hallman II, J.D.3
  • 79
    • 0033039308 scopus 로고    scopus 로고
    • Direct translation of a protracted irinotecan schedule from a xenograft model to a phase I trial in children
    • Furman WL, Stewart CF, Poquette CA, et al.: Direct translation of a protracted irinotecan schedule from a xenograft model to a phase I trial in children. J Clin Oncol 1999, 17:1815-1824.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1815-1824
    • Furman, W.L.1    Stewart, C.F.2    Poquette, C.A.3
  • 80
    • 0036171172 scopus 로고    scopus 로고
    • Irinotecan for pediatric solid tumors: The Memorial Sloan-Kettering experience
    • Cosetti M, Wexler LH, Calleja E, et al.: Irinotecan for pediatric solid tumors: the Memorial Sloan-Kettering experience. J Pediatr Hematol Oncol 2002, 24:101-105. x
    • (2002) J. Pediatr. Hematol. Oncol. , vol.24 , pp. 101-105
    • Cosetti, M.1    Wexler, L.H.2    Calleja, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.