Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis

Journal of Biological Chemistry

Volumn 278, Issue 9, 2003, Pages 6848-6853

  Chen, Feng ^a   Chang, Roger ^a   Trivedi, Marcus ^a   Capetanaki, Yassemi ^b   Cryns, Vincent L ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUSCLE; MUTAGENESIS; PROTEINS;

APOPTOSIS;

BIOCHEMISTRY;

ASPARTIC ACID; CASPASE; CASPASE 6; CYTOSKELETON PROTEIN; DESMIN; INTERMEDIATE FILAMENT PROTEIN; N DESMIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CASP6 PROTEIN, HUMAN; CASP6 PROTEIN, MOUSE; CASP6 PROTEIN, RAT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; INTERMEDIATE FILAMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN TARGETING; RAT; ANIMAL; CELL CULTURE; CELL LINE; DOMINANT GENE; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOBLOTTING; METABOLISM; PLASMID; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; TIME;

ANIMALIA;

ANIMALS; APOPTOSIS; ASPARTIC ACID; CASPASE 6; CASPASES; CELL LINE; DESMIN; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENES, DOMINANT; HUMANS; IMMUNOBLOTTING; MICE; MUTAGENESIS, SITE-DIRECTED; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037470243     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212021200     Document Type: Article

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