Tamoxifen encapsulation within polyethylene glycol-coated nanospheres. A new antiestrogen formulation

International Journal of Pharmaceutics

Volumn 214, Issue 1-2, 2001, Pages 37-42

  Brigger, I ^a   Chaminade, P ^b   Marsaud, V ^a   Appel, M ^a   Besnard, M ^a   Gurny, R ^c   Renoir, M ^a   Couvreur, P ^a  

^a UNIV PARIS SUD   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Nanospheres; Near infrared hydrophilic hydrophobic model; Poly(MePEGcyanoacrylate co hexadecylcyanoacrylate); Tamoxifen; Transcription inhibitory activity

Indexed keywords

ANTIESTROGEN; COPOLYMER; NANOPARTICLE; POLOXAMER; TAMOXIFEN; TUMOR NECROSIS FACTOR ALPHA;

BREAST CANCER; CANCER CELL; CANCER CHEMOTHERAPY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SYNTHESIS; ENCAPSULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; INFRARED RADIATION; PRIORITY JOURNAL; ZETA POTENTIAL;

DRUG DELIVERY SYSTEMS; ESTROGEN RECEPTOR MODULATORS; MICELLES; POLYETHYLENE GLYCOLS; SPECTROSCOPY, NEAR-INFRARED; TAMOXIFEN;

EID: 0035910880     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00628-1     Document Type: Conference Paper

References (10)

1. Near infrared with principal component analysis as a novel analytical approach for nanoparticle technology
2. Data treatment in near infrared spectroscopy
3. MVLN cells: A bioluminescent MCE-7-derived cell line to study the modulation of estrogenic activity
4. Liposome circulation time and tumor targeting: Implications for cancer chemotherapy
5. Basic guide to the mechanisms of antiestrogen action
6. Pegylated nanoparticles from a novel methoxypolyethylene glycol cyanoacrylate-hexadecyl cyanoacrylate amphiphilic copolymer
7. Stealth® pegylated polycyanoacrylate nanoparticles for intravenous administration and splenic targeting
8. Passive tumor targeting of soluble macromolecules and drug conjugates
9. Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system
10. Antiestrogen: Tamoxifen