Pharmacokinetics and biodistribution of oligonucleotide adsorbed onto poly(isobutylcyanoacrylate) nanoparticles after intravenous administration in mice

Pharmaceutical Research

Volumn 13, Issue 1, 1996, Pages 38-43

  Nakada, Yuichiro ^a,b   Fattal, Elias ^b   Foulquier, Monique ^b   Couvreur, Patrick ^b  

^a KANEBO LTD   (Japan)

^b CNRS   (France)

Author keywords

Nanoparticles; Oligonucleotides; Pharmacokinetics; Poly(isobutylcyanoacrylate); Stability; Tissue distribution

Indexed keywords

BUCRILATE; NANOPARTICLE; OLIGONUCLEOTIDE;

ANIMAL EXPERIMENT; ARTICLE; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG STABILITY; DRUG TARGETING; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

ADSORPTION; ANIMALS; CYANOACRYLATES; DRUG CARRIERS; DRUG STABILITY; EVALUATION STUDIES; INJECTIONS, INTRAVENOUS; LIVER; MICE; MICE, INBRED STRAINS; MICROSPHERES; PARTICLE SIZE; POLYMERS; THYMINE NUCLEOTIDES; TISSUE DISTRIBUTION;

EID: 0029983418     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016017014573     Document Type: Article

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