메뉴 건너뛰기




Volumn 88, Issue 6, 2003, Pages 918-927

TRAIL-β and TRAIL-γ two novel splice variants of the human TNF-related apoptosis-inducing ligand (TRAIL) without apoptotic potential

Author keywords

Alternative splicing; Apoptosis; Neoplastic cells; TRAIL

Indexed keywords

SPLICED LEADER RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND BETA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND GAMMA; UNCLASSIFIED DRUG;

EID: 0037464356     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600772     Document Type: Article
Times cited : (34)

References (57)
  • 3
    • 0025882349 scopus 로고
    • PROSITE: A dictionary of sites and patterns in proteins
    • Bairoch A (1991) PROSITE: a dictionary of sites and patterns in proteins. Nucleic Acids Res 19: 2241-2245
    • (1991) Nucleic Acids Res , vol.19 , pp. 2241-2245
    • Bairoch, A.1
  • 4
    • 0035920230 scopus 로고    scopus 로고
    • Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1
    • Bernard D, Quatannens B, Vandenbunder B, Abbadie C (2001) Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1. J Biol Chem 276: 27322-27328
    • (2001) J Biol Chem , vol.276 , pp. 27322-27328
    • Bernard, D.1    Quatannens, B.2    Vandenbunder, B.3    Abbadie, C.4
  • 6
    • 0034617304 scopus 로고    scopus 로고
    • Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL
    • Bodmer JL, Meier P, Tschopp J, Schneider P (2000b) Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL. J Biol Chem 275: 20632-20637
    • (2000) J Biol Chem , vol.275 , pp. 20632-20637
    • Bodmer, J.L.1    Meier, P.2    Tschopp, J.3    Schneider, P.4
  • 8
    • 0028963667 scopus 로고
    • Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing
    • Cascino I, Fiucci G, Papoff G, Ruberti G (1995) Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing. J Immunol 154: 2706-2713
    • (1995) J Immunol , vol.154 , pp. 2706-2713
    • Cascino, I.1    Fiucci, G.2    Papoff, G.3    Ruberti, G.4
  • 10
    • 0035970031 scopus 로고    scopus 로고
    • Caspase-2 pre-mRNA alternative splicing: Identification of an intronic element containing a decoy 3′ acceptor site
    • Cote J, Dupuis S, Jiang Z, Wu JY (2001) Caspase-2 pre-mRNA alternative splicing: identification of an intronic element containing a decoy 3′ acceptor site. Proc Natl Acad Sci USA 98: 938-943
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 938-943
    • Cote, J.1    Dupuis, S.2    Jiang, Z.3    Wu, J.Y.4
  • 11
    • 0032942436 scopus 로고    scopus 로고
    • To die or not to die - The quest of the TRAIL receptors
    • Degli-Esposti MA (1999) To die or not to die - the quest of the TRAIL receptors. J Leuk Biol 65: 535-542
    • (1999) J Leuk Biol , vol.65 , pp. 535-542
    • Degli-Esposti, M.A.1
  • 12
    • 0031414749 scopus 로고    scopus 로고
    • The novel receptor TRAIL-R4 induces NF-κB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
    • Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG (1997a) The novel receptor TRAIL-R4 induces NF-κB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 7: 813-820
    • (1997) Immunity , vol.7 , pp. 813-820
    • Degli-Esposti, M.A.1    Dougall, W.C.2    Smolak, P.J.3    Waugh, J.Y.4    Smith, C.A.5    Goodwin, R.G.6
  • 14
    • 0033710429 scopus 로고    scopus 로고
    • Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan
    • Dejosez M, Ramp U, Mahotka C, Krieg A, Walczak H, Gabbert HE, Gerharz CD (2000) Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan. Cell Death Differ 7: 1127-1136
    • (2000) Cell Death Differ , vol.7 , pp. 1127-1136
    • Dejosez, M.1    Ramp, U.2    Mahotka, C.3    Krieg, A.4    Walczak, H.5    Gabbert, H.E.6    Gerharz, C.D.7
  • 16
    • 0035866396 scopus 로고    scopus 로고
    • Resistance to tumor necrosis factor related apoptosis-inducing ligand-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression
    • Eggert A, Grotzer MA, Zuzak TJ, Wiewrodt BR, Ho R, Ikegaki N, Brodeur GM (2001) Resistance to tumor necrosis factor related apoptosis-inducing ligand-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression. Cancer Res 61: 1314-1319
    • (2001) Cancer Res , vol.61 , pp. 1314-1319
    • Eggert, A.1    Grotzer, M.A.2    Zuzak, T.J.3    Wiewrodt, B.R.4    Ho, R.5    Ikegaki, N.6    Brodeur, G.M.7
  • 19
    • 0034192904 scopus 로고    scopus 로고
    • Regulation of TRAIL-induced apoptosis by transcription factors
    • Goke R, Goke A, Goke B, Chen Y (2000) Regulation of TRAIL-induced apoptosis by transcription factors. Cell Immunol 201: 77-82
    • (2000) Cell Immunol , vol.201 , pp. 77-82
    • Goke, R.1    Goke, A.2    Goke, B.3    Chen, Y.4
  • 20
    • 0034736062 scopus 로고    scopus 로고
    • Genomic organization and transcriptional regulation of human Apo2/TRAIL gene
    • Gong B, Almasan A (2000) Genomic organization and transcriptional regulation of human Apo2/TRAIL gene. Biochem Biophys Res Commun 278: 747-752
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 747-752
    • Gong, B.1    Almasan, A.2
  • 21
    • 0032530612 scopus 로고    scopus 로고
    • Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
    • Griffith TS, Chin WA, Jackson GC, Lynch DH, Kubin MZ (1998) Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J Immunol 161: 2833-2840
    • (1998) J Immunol , vol.161 , pp. 2833-2840
    • Griffith, T.S.1    Chin, W.A.2    Jackson, G.C.3    Lynch, D.H.4    Kubin, M.Z.5
  • 22
    • 0031782909 scopus 로고    scopus 로고
    • TRAIL: A molecule with multiple receptors and control mechanisms
    • Griffith TS, Lynch DH (1998) TRAIL: a molecule with multiple receptors and control mechanisms. Curr Opin Immunol 10: 559-563
    • (1998) Curr Opin Immunol , vol.10 , pp. 559-563
    • Griffith, T.S.1    Lynch, D.H.2
  • 23
    • 0030763774 scopus 로고    scopus 로고
    • How TRAIL kills cancer cells but not normal cells
    • Gura T (1997) How TRAIL kills cancer cells but not normal cells. Science 277: 68
    • (1997) Science , vol.277 , pp. 68
    • Gura, T.1
  • 24
    • 0035860696 scopus 로고    scopus 로고
    • Modulation of tumor necrosis factor apoptosis-inducing ligand-induced NF-κB activation by inhibition of apical caspases
    • Harper N, Farrow SN, Kaptein A, Cohen GM, MacFarlane M (2001) Modulation of tumor necrosis factor apoptosis-inducing ligand-induced NF-κB activation by inhibition of apical caspases. J Biol Chem 276: 34743-34752
    • (2001) J Biol Chem , vol.276 , pp. 34743-34752
    • Harper, N.1    Farrow, S.N.2    Kaptein, A.3    Cohen, G.M.4    MacFarlane, M.5
  • 25
    • 0031810458 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells
    • Jeremias I, Kupatt C, Baumann B, Herr I, Wirth T, Debatin KM (1998) Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells. Blood 91: 4624-4631
    • (1998) Blood , vol.91 , pp. 4624-4631
    • Jeremias, I.1    Kupatt, C.2    Baumann, B.3    Herr, I.4    Wirth, T.5    Debatin, K.M.6
  • 26
    • 0032914182 scopus 로고    scopus 로고
    • Alternative splicing and programmed cell death
    • Jiang ZH, Wu JY (1999) Alternative splicing and programmed cell death. Proc Soc Exp Biol Med 220: 64-72
    • (1999) Proc Soc Exp Biol Med , vol.220 , pp. 64-72
    • Jiang, Z.H.1    Wu, J.Y.2
  • 27
    • 0032482968 scopus 로고    scopus 로고
    • Regulation of Ich-1 pre-mRNA alternative splicing and apoptosis by mammalian splicing factors
    • Jiang ZH, Zhang WJ, Rao Y, Wu JY (1998) Regulation of Ich-1 pre-mRNA alternative splicing and apoptosis by mammalian splicing factors. Proc Natl Acad Sci USA 95: 9155-9160
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9155-9160
    • Jiang, Z.H.1    Zhang, W.J.2    Rao, Y.3    Wu, J.Y.4
  • 28
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M, Kim TH, Seol DW, Esplen JE, Dorko K, Billiar TR, Strom SC (2000) Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 6: 564-567
    • (2000) Nat Med , vol.6 , pp. 564-567
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3    Esplen, J.E.4    Dorko, K.5    Billiar, T.R.6    Strom, S.C.7
  • 29
    • 0035870294 scopus 로고    scopus 로고
    • Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene
    • Kagawa S, He C, Gu J, Koch P, Rha SJ, Roth JA, Curley SA, Stephens LC, Fang B (2001) Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene. Cancer Res 61: 3330-3338
    • (2001) Cancer Res , vol.61 , pp. 3330-3338
    • Kagawa, S.1    He, C.2    Gu, J.3    Koch, P.4    Rha, S.J.5    Roth, J.A.6    Curley, S.A.7    Stephens, L.C.8    Fang, B.9
  • 31
    • 0033662433 scopus 로고    scopus 로고
    • Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
    • Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A (2000) Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 12: 611-620
    • (2000) Immunity , vol.12 , pp. 611-620
    • Kischkel, F.C.1    Lawrence, D.A.2    Chuntharapai, A.3    Schow, P.4    Kim, K.J.5    Ashkenazi, A.6
  • 33
    • 0034682802 scopus 로고    scopus 로고
    • FADD is required for DR4- and DR5-mediated apoptosis: Lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts
    • Kuang AA, Diehl GE, Zhang J, Winoto A (2000) FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts. J Biol Chem 275: 25065-25068
    • (2000) J Biol Chem , vol.275 , pp. 25065-25068
    • Kuang, A.A.1    Diehl, G.E.2    Zhang, J.3    Winoto, A.4
  • 34
    • 0033975513 scopus 로고    scopus 로고
    • Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes
    • Leverkus M, Neumann M, Mengling T, Rauch CT, Brocker EB, Krammer PH, Walczak H (2000) Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes. Cancer Res 60: 553-559
    • (2000) Cancer Res , vol.60 , pp. 553-559
    • Leverkus, M.1    Neumann, M.2    Mengling, T.3    Rauch, C.T.4    Brocker, E.B.5    Krammer, P.H.6    Walczak, H.7
  • 36
    • 0033571983 scopus 로고    scopus 로고
    • Survivin-ΔEx3 and Survivin-2B: Two novel splice variants of the apoptosis inhibitor survivin with different anti-apoptotic properties
    • Mahotka C, Wenzel M, Springer E, Gabbert HE, Gerharz CD (1999) Survivin-ΔEx3 and Survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different anti-apoptotic properties. Cancer Res 59: 6097-6102
    • (1999) Cancer Res , vol.59 , pp. 6097-6102
    • Mahotka, C.1    Wenzel, M.2    Springer, E.3    Gabbert, H.E.4    Gerharz, C.D.5
  • 37
    • 0031945015 scopus 로고    scopus 로고
    • Surface expression of TRAIL/Apo-2 ligand in activated mouse T and B cells
    • Mariani SM, Krammer PH (1998) Surface expression of TRAIL/Apo-2 ligand in activated mouse T and B cells. Eur J Immunol 28: 1492-1498
    • (1998) Eur J Immunol , vol.28 , pp. 1492-1498
    • Mariani, S.M.1    Krammer, P.H.2
  • 39
    • 0035374366 scopus 로고    scopus 로고
    • A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins
    • Miyazaki T, Reed JC (2001) A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins. Nat Immunol 2: 493-500
    • (2001) Nat Immunol , vol.2 , pp. 493-500
    • Miyazaki, T.1    Reed, J.C.2
  • 40
    • 0031627483 scopus 로고    scopus 로고
    • Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): A new receptor protecting lymphocytes from the death ligand TRAIL
    • Mongkolsapaya J, Cowper AE, Xu XN, Morris G, McMichael AJ, Bell JI, Screaton GR (1998) Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): a new receptor protecting lymphocytes from the death ligand TRAIL. J Immunol 160: 3-6
    • (1998) J Immunol , vol.160 , pp. 3-6
    • Mongkolsapaya, J.1    Cowper, A.E.2    Xu, X.N.3    Morris, G.4    McMichael, A.J.5    Bell, J.I.6    Screaton, G.R.7
  • 41
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxity assays
    • Mosman T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxity assays. J Immunol Methods 65: 55-64
    • (1983) J Immunol Methods , vol.65 , pp. 55-64
    • Mosman, T.1
  • 42
    • 0032972509 scopus 로고    scopus 로고
    • PSORT: A program for detecting sorting signals in proteins and predicting their subcellular localization
    • Nakai K, Horton P (1999) PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem Sci 24: 34-36
    • (1999) Trends Biochem Sci , vol.24 , pp. 34-36
    • Nakai, K.1    Horton, P.2
  • 43
    • 0035963273 scopus 로고    scopus 로고
    • Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells
    • Oya M, Ohtsubo M, Takayanagi A, Tachibana M, Shimizu N, Murai M (2001) Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells. Oncogene 20: 3888-3896
    • (2001) Oncogene , vol.20 , pp. 3888-3896
    • Oya, M.1    Ohtsubo, M.2    Takayanagi, A.3    Tachibana, M.4    Shimizu, N.5    Murai, M.6
  • 44
    • 0030762815 scopus 로고    scopus 로고
    • An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    • Pan G, Ni J, Wie YF, Yu G, Gentz R, Dixit VM (1997a) An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 277: 815-818
    • (1997) Science , vol.277 , pp. 815-818
    • Pan, G.1    Ni, J.2    Wie, Y.F.3    Yu, G.4    Gentz, R.5    Dixit, V.M.6
  • 46
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A (1996) Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271: 12687-12690
    • (1996) J Biol Chem , vol.271 , pp. 12687-12690
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5    Ashkenazi, A.6
  • 48
    • 0033556310 scopus 로고    scopus 로고
    • The role of c-FLIP in modulation of CD95-induced apoptosis
    • Scaffidi C, Schmitz I, Krammer PH, Peter ME (1999) The role of c-FLIP in modulation of CD95-induced apoptosis. J Biol Chem 274: 1541-1548
    • (1999) J Biol Chem , vol.274 , pp. 1541-1548
    • Scaffidi, C.1    Schmitz, I.2    Krammer, P.H.3    Peter, M.E.4
  • 50
    • 0033667778 scopus 로고    scopus 로고
    • FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
    • Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, Krammer PH, Walczak H (2000) FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12: 599-609
    • (2000) Immunity , vol.12 , pp. 599-609
    • Sprick, M.R.1    Weigand, M.A.2    Rieser, E.3    Rauch, C.T.4    Juo, P.5    Blenis, J.6    Krammer, P.H.7    Walczak, H.8
  • 52
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice
    • Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680
    • (1994) Nucleic Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 56
    • 0034989624 scopus 로고    scopus 로고
    • In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity
    • Wuchter C, Krappmann D, Cai Z, Ruppert V, Scheidereit C, Dorken B, Ludwig WD, Karawajew L (2001) In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity. Leukemia 15: 921-928
    • (2001) Leukemia , vol.15 , pp. 921-928
    • Wuchter, C.1    Krappmann, D.2    Cai, Z.3    Ruppert, V.4    Scheidereit, C.5    Dorken, B.6    Ludwig, W.D.7    Karawajew, L.8
  • 57
    • 0013583837 scopus 로고    scopus 로고
    • Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
    • Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P (1999) Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res 59: 2747-2753
    • (1999) Cancer Res , vol.59 , pp. 2747-2753
    • Zhang, X.D.1    Franco, A.2    Myers, K.3    Gray, C.4    Nguyen, T.5    Hersey, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.