Toxic effects of MPP+ and MPTP in PC12 cells independent of reactive oxygen species formation

Brain Research

Volumn 905, Issue 1-2, 2001, Pages 199-206

  Fonck, Carlos ^a   Baudry, Michel ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

6 OHDA; Dopaminergic; Free radical; MPP+; MPTP; Parkinson's disease; PC12

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ACETYLCYSTEINE; ANTIOXIDANT; GLUTATHIONE; MANGANESE N,N' ETHYLENEBIS(3 METHOXYSALICYLIDENEAMINE); OXIDOPAMINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SCAVENGER; TERT BUTYL HYDROPEROXIDE;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DRUG CYTOTOXICITY; DRUG EFFECT; ENERGY METABOLISM; INCUBATION TIME; LIPID PEROXIDATION; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; RAT;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; 1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; DOPAMINE; DOPAMINE AGENTS; DRUG INTERACTIONS; FREE RADICAL SCAVENGERS; HERBICIDES; LIPID PEROXIDATION; NAD; NERVE GROWTH FACTOR; NEURONS; OXIDOPAMINE; PARKINSONIAN DISORDERS; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; SUBSTANTIA NIGRA; TRITIUM;

EID: 0035968068     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02551-3     Document Type: Article

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