-
1
-
-
0030928225
-
Pharmacology of neurotrophic factors
-
Hefti F. Pharmacology of neurotrophic factors. Annu. Rev. Pharmacol. Toxicol. 37:1997;239-267.
-
(1997)
Annu. Rev. Pharmacol. Toxicol.
, vol.37
, pp. 239-267
-
-
Hefti, F.1
-
2
-
-
0032102110
-
The role of neuronal growth factors in neurodegenerative disorders of the human brain
-
Connor B., Dragunow M. The role of neuronal growth factors in neurodegenerative disorders of the human brain. Brain Res. Rev. 27:1998;1-39.
-
(1998)
Brain Res. Rev.
, vol.27
, pp. 1-39
-
-
Connor, B.1
Dragunow, M.2
-
3
-
-
0031924935
-
Localized delivery of proteins in the brain: Can transport be customized?
-
Haller M.F., Saltzman W.M. Localized delivery of proteins in the brain: can transport be customized? Pharm. Res. 15:1998;377-385.
-
(1998)
Pharm. Res.
, vol.15
, pp. 377-385
-
-
Haller, M.F.1
Saltzman, W.M.2
-
4
-
-
0035451329
-
Recombinant proteins for neurodegenerative diseases: The delivery issue
-
Aebischer P., Ridet J. Recombinant proteins for neurodegenerative diseases: the delivery issue. Trends Neurosci. 24:2001;533-540.
-
(2001)
Trends Neurosci.
, vol.24
, pp. 533-540
-
-
Aebischer, P.1
Ridet, J.2
-
5
-
-
0027380155
-
Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection
-
Morse J.K., Wiegand S.J., Anderson K., You Y., Cai N., Carnahan J., Miller J., DiStefano P.S., Altar C.A., Lindsay R.M. Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection. J. Neurosci. 13:1993;4146-4156.
-
(1993)
J. Neurosci.
, vol.13
, pp. 4146-4156
-
-
Morse, J.K.1
Wiegand, S.J.2
Anderson, K.3
You, Y.4
Cai, N.5
Carnahan, J.6
Miller, J.7
DiStefano, P.S.8
Altar, C.A.9
Lindsay, R.M.10
-
6
-
-
0028289716
-
Distribution of intracerebral ventricularly administered neurotrophins in rat brain and its correlation with trk receptor expression
-
Yan Q., Matheson C., Sun J., Radeke M.J., Feinstein S.C., Miller J.A. Distribution of intracerebral ventricularly administered neurotrophins in rat brain and its correlation with trk receptor expression. Exp. Neurol. 127:1994;23-36.
-
(1994)
Exp. Neurol.
, vol.127
, pp. 23-36
-
-
Yan, Q.1
Matheson, C.2
Sun, J.3
Radeke, M.J.4
Feinstein, S.C.5
Miller, J.A.6
-
7
-
-
0026512910
-
Nerve growth factor affects 11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (case report)
-
Olson L., Nordberg A., von Holst H., Backman L., Ebendal T., Alafuzoff I., Amberla K., Hartvig P., Herlitz A., Lilja A., et al. Nerve growth factor affects 11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (case report). J. Neural Transm. Park. Dis. Dement. Sect. 4:1992;79-95.
-
(1992)
J. Neural Transm. Park. Dis. Dement. Sect.
, vol.4
, pp. 79-95
-
-
Olson, L.1
Nordberg, A.2
Von Holst, H.3
Backman, L.4
Ebendal, T.5
Alafuzoff, I.6
Amberla, K.7
Hartvig, P.8
Herlitz, A.9
Lilja, A.10
-
8
-
-
0005868926
-
Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease
-
Eriksdotter Jonhagen M., Nordberg A., Amberla K., Backman L., Ebendal T., Meyerson B., Olson L., et al. Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 9:1998;246-257.
-
(1998)
Dement. Geriatr. Cogn. Disord.
, vol.9
, pp. 246-257
-
-
Eriksdotter Jonhagen, M.1
Nordberg, A.2
Amberla, K.3
Backman, L.4
Ebendal, T.5
Meyerson, B.6
Olson, L.7
-
9
-
-
0032850453
-
Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease
-
Kordower J.H., Palfi S., Chen E.Y., Ma S.Y., Sendera T., Cochran E.J., Mufson E.J., Penn R., Goetz C.G., Comella C.D. Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease. Ann. Neurol. 46:1999;419-424.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 419-424
-
-
Kordower, J.H.1
Palfi, S.2
Chen, E.Y.3
Ma, S.Y.4
Sendera, T.5
Cochran, E.J.6
Mufson, E.J.7
Penn, R.8
Goetz, C.G.9
Comella, C.D.10
-
10
-
-
0029009934
-
Differential distribution of exogenous BDNF, NGF, and NT-3 in the brain corresponds to the relative abundance and distribution of high-affinity and low-affinity neurotrophin receptors
-
Anderson K.D., Alderson R.F., Altar C.A., DiStefano P.S., Corcoran T.L., Lindsay R.M., Wiegand S.J. Differential distribution of exogenous BDNF, NGF, and NT-3 in the brain corresponds to the relative abundance and distribution of high-affinity and low-affinity neurotrophin receptors. J. Comp. Neurol. 357:1995;296-317.
-
(1995)
J. Comp. Neurol.
, vol.357
, pp. 296-317
-
-
Anderson, K.D.1
Alderson, R.F.2
Altar, C.A.3
DiStefano, P.S.4
Corcoran, T.L.5
Lindsay, R.M.6
Wiegand, S.J.7
-
11
-
-
0030690936
-
A gene therapy approach to regulated delivery of erythropoietin as a function of oxygen tension
-
Rinsch C., Regulier E., Déglon N., Dalle B., Beuzard Y., Aebischer P. A gene therapy approach to regulated delivery of erythropoietin as a function of oxygen tension. Hum. Gene Ther. 8:1997;1881-1889.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 1881-1889
-
-
Rinsch, C.1
Regulier, E.2
Déglon, N.3
Dalle, B.4
Beuzard, Y.5
Aebischer, P.6
-
12
-
-
0029846012
-
Central nervous system delivery of recombinant ciliary neurotrophic factor by polymer encapsulated differentiated C2C12 myoblasts
-
Déglon N., Heyd B., Tan S.A., Joseph J.M., Zurn A.D., Aebischer P. Central nervous system delivery of recombinant ciliary neurotrophic factor by polymer encapsulated differentiated C2C12 myoblasts. Hum. Gene Ther. 7:1996;2135-2146.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 2135-2146
-
-
Déglon, N.1
Heyd, B.2
Tan, S.A.3
Joseph, J.M.4
Zurn, A.D.5
Aebischer, P.6
-
13
-
-
13344293675
-
Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells
-
Moens K., Heimberg H., Flamez D., Huypens P., Quartier E., Ling Z., Pipeleers D., Gremlich S., Thorens B., Schuit F. Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Diabetes. 45:1996;257-261.
-
(1996)
Diabetes
, vol.45
, pp. 257-261
-
-
Moens, K.1
Heimberg, H.2
Flamez, D.3
Huypens, P.4
Quartier, E.5
Ling, Z.6
Pipeleers, D.7
Gremlich, S.8
Thorens, B.9
Schuit, F.10
-
14
-
-
0034255026
-
Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus
-
Hottinger A.F., Azzouz M., Déglon N., Aebischer P., Zurn A.D. Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus. J. Neurosci. 20:2000;5587-5593.
-
(2000)
J. Neurosci.
, vol.20
, pp. 5587-5593
-
-
Hottinger, A.F.1
Azzouz, M.2
Déglon, N.3
Aebischer, P.4
Zurn, A.D.5
-
15
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
-
Kordower J.H., Emborg M.E., Bloch J., Ma S.Y., Chu Y.P., Leventhal L., McBride J., Chen E.Y., Palfi S., Roitberg B.Z., Brown W.D., Holden J.E., Pyzalski R., Taylor M.D., Carvey P., Ling Z.D., Trono D., Hantraye P., Deglon N., Aebischer P. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science. 290:2000;767-773.
-
(2000)
Science
, vol.290
, pp. 767-773
-
-
Kordower, J.H.1
Emborg, M.E.2
Bloch, J.3
Ma, S.Y.4
Chu, Y.P.5
Leventhal, L.6
McBride, J.7
Chen, E.Y.8
Palfi, S.9
Roitberg, B.Z.10
Brown, W.D.11
Holden, J.E.12
Pyzalski, R.13
Taylor, M.D.14
Carvey, P.15
Ling, Z.D.16
Trono, D.17
Hantraye, P.18
Deglon, N.19
Aebischer, P.20
more..
-
17
-
-
0025115891
-
NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria-fornix lesion
-
Hoffman D., Wahlberg L., Aebischer P. NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria-fornix lesion. Exp. Neurol. 110:1990;39-44.
-
(1990)
Exp. Neurol.
, vol.110
, pp. 39-44
-
-
Hoffman, D.1
Wahlberg, L.2
Aebischer, P.3
-
18
-
-
0343517501
-
Implantation of bioactive growth factor-secreting rods enhances fetal dopaminergic graft survival, outgrowth density, and functional recovery in a rat model of Parkinson's disease
-
Tornqvist N., Björklund L., Almqvist P., Wahlberg L., Stromberg I. Implantation of bioactive growth factor-secreting rods enhances fetal dopaminergic graft survival, outgrowth density, and functional recovery in a rat model of Parkinson's disease. Exp. Neurol. 164:2000;130-138.
-
(2000)
Exp. Neurol.
, vol.164
, pp. 130-138
-
-
Tornqvist, N.1
Björklund, L.2
Almqvist, P.3
Wahlberg, L.4
Stromberg, I.5
-
19
-
-
0031031008
-
GDNF reduces drug-induced rotational behavior after medial forebrain bundle transection by a mechanism not involving striatal dopamine
-
Tseng J.L., Baetge E.E., Zurn A.D., Aebischer P. GDNF reduces drug-induced rotational behavior after medial forebrain bundle transection by a mechanism not involving striatal dopamine. J. Neurosci. 17:1997;325-333.
-
(1997)
J. Neurosci.
, vol.17
, pp. 325-333
-
-
Tseng, J.L.1
Baetge, E.E.2
Zurn, A.D.3
Aebischer, P.4
-
20
-
-
0031936437
-
Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts
-
Sautter J., Tseng J.L., Braguglia D., Aebischer P., Spenger C., Seiler R.W., Widmer H.R., Zurn A.D. Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts. Exp. Neurol. 149:1998;230-236.
-
(1998)
Exp. Neurol.
, vol.149
, pp. 230-236
-
-
Sautter, J.1
Tseng, J.L.2
Braguglia, D.3
Aebischer, P.4
Spenger, C.5
Seiler, R.W.6
Widmer, H.R.7
Zurn, A.D.8
-
21
-
-
0032102162
-
Neurturin protects dopaminergic neurons following medial forebrain bundle axotomy
-
Tseng J.L., Bruhn S.L., Zurn A.D., Aebischer P. Neurturin protects dopaminergic neurons following medial forebrain bundle axotomy. NeuroReport. 9:1998;1817-1822.
-
(1998)
NeuroReport
, vol.9
, pp. 1817-1822
-
-
Tseng, J.L.1
Bruhn, S.L.2
Zurn, A.D.3
Aebischer, P.4
-
22
-
-
0031920726
-
Cellular delivery of CNTF but not NT-4/5 prevents degeneration of striatal neurons in a rodent model of Huntington's disease
-
Emerich D.F., Bruhn S., Chu Y., Kordower J.H. Cellular delivery of CNTF but not NT-4/5 prevents degeneration of striatal neurons in a rodent model of Huntington's disease. Cell Transplant. 7:1998;213-225.
-
(1998)
Cell Transplant.
, vol.7
, pp. 213-225
-
-
Emerich, D.F.1
Bruhn, S.2
Chu, Y.3
Kordower, J.H.4
-
23
-
-
0029761786
-
Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease
-
Emerich D.F., Lindner M.D., Winn S.R., Chen E.Y., Frydel B.R., Kordower J.H. Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease. J. Neurosci. 16:1996;5168-5181.
-
(1996)
J. Neurosci.
, vol.16
, pp. 5168-5181
-
-
Emerich, D.F.1
Lindner, M.D.2
Winn, S.R.3
Chen, E.Y.4
Frydel, B.R.5
Kordower, J.H.6
-
24
-
-
0030906578
-
Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease
-
Emerich D.F., Winn S.R., Hantraye P.M., Peschanski M., Chen E.Y., Chu Y., McDermott P., Baetge E.E., Kordower J.H. Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease. Nature. 386:1997;395-399.
-
(1997)
Nature
, vol.386
, pp. 395-399
-
-
Emerich, D.F.1
Winn, S.R.2
Hantraye, P.M.3
Peschanski, M.4
Chen, E.Y.5
Chu, Y.6
McDermott, P.7
Baetge, E.E.8
Kordower, J.H.9
-
25
-
-
0034690615
-
Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease
-
Mittoux V., Joseph J.M., Conde F., Palfi S., Dautry C., Poyot T., Bloch J., Deglon N., Ouary S., Nimchinsky E.A., Brouillet E., Hof P.R., Peschanski M., Aebischer P., Hantraye P. Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease. Hum. Gene Ther. 11:2000;1177-1187.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 1177-1187
-
-
Mittoux, V.1
Joseph, J.M.2
Conde, F.3
Palfi, S.4
Dautry, C.5
Poyot, T.6
Bloch, J.7
Deglon, N.8
Ouary, S.9
Nimchinsky, E.A.10
Brouillet, E.11
Hof, P.R.12
Peschanski, M.13
Aebischer, P.14
Hantraye, P.15
-
26
-
-
15844381714
-
Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients
-
Aebischer P., Schluep M., Déglon N., Joseph J.M., Hirt L., Heyd B., Goddard M., Hammang J.P., Zurn A.D., Kato A.C., Regli F., Baetge E.E. Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients. Nat. Med. 2:1996;696-699.
-
(1996)
Nat. Med.
, vol.2
, pp. 696-699
-
-
Aebischer, P.1
Schluep, M.2
Déglon, N.3
Joseph, J.M.4
Hirt, L.5
Heyd, B.6
Goddard, M.7
Hammang, J.P.8
Zurn, A.D.9
Kato, A.C.10
Regli, F.11
Baetge, E.E.12
-
27
-
-
0033771207
-
Evaluation of an intrathecal immune response in amyotrophic lateral sclerosis patients implanted with encapsulated genetically engineered xenogeneic cells
-
Zurn A.D., Henry H., Schluep M., Aubert V., Winkel L., Eilers B., Bachmann C., Aebischer P. Evaluation of an intrathecal immune response in amyotrophic lateral sclerosis patients implanted with encapsulated genetically engineered xenogeneic cells. Cell Transplant. 9:2000;471-484.
-
(2000)
Cell Transplant.
, vol.9
, pp. 471-484
-
-
Zurn, A.D.1
Henry, H.2
Schluep, M.3
Aubert, V.4
Winkel, L.5
Eilers, B.6
Bachmann, C.7
Aebischer, P.8
-
28
-
-
0032191380
-
Lentiviruses as gene transfer agents for delivery to non-dividing cells
-
Naldini L. Lentiviruses as gene transfer agents for delivery to non-dividing cells. Curr. Opin. Biotechnol. 9:1998;457-463.
-
(1998)
Curr. Opin. Biotechnol.
, vol.9
, pp. 457-463
-
-
Naldini, L.1
-
29
-
-
0034278156
-
Lentiviral vectors: Excellent tools for experimental gene transfer and promising candidates for gene therapy
-
Vigna E., Naldini L. Lentiviral vectors: excellent tools for experimental gene transfer and promising candidates for gene therapy. J. Gene Med. 2:2000;308-316.
-
(2000)
J. Gene Med.
, vol.2
, pp. 308-316
-
-
Vigna, E.1
Naldini, L.2
-
30
-
-
0033977265
-
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
-
Déglon N., Tseng J.L., Bensadoun J.C., Zurn A.D., Arsenijevic Y., Pereira de Almeida L., Zufferey R., Trono D., Aebischer P. Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease. Hum. Gene Ther. 11:2000;179-190.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 179-190
-
-
Déglon, N.1
Tseng, J.L.2
Bensadoun, J.C.3
Zurn, A.D.4
Arsenijevic, Y.5
Pereira de Almeida, L.6
Zufferey, R.7
Trono, D.8
Aebischer, P.9
-
31
-
-
0343517507
-
Lentiviral vectors as a gene delivery system in the mouse midbrain: Cellular and behavioural improvements in a 6-OHDA model of Parkinson's disease using GDNF
-
Bensadoun J.C., Déglon N., Tseng J.L., Ridet J.L., Zurn A.D., Aebischer P. Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioural improvements in a 6-OHDA model of Parkinson's disease using GDNF. Exp. Neurol. 164:2000;15-24.
-
(2000)
Exp. Neurol.
, vol.164
, pp. 15-24
-
-
Bensadoun, J.C.1
Déglon, N.2
Tseng, J.L.3
Ridet, J.L.4
Zurn, A.D.5
Aebischer, P.6
-
32
-
-
0033759915
-
Development of multigene and regulated lentivirus vectors
-
Reiser J., Lai Z.N., Zhang X.Y., Brady R.O. Development of multigene and regulated lentivirus vectors. J. Virol. 74:2000;10589-10599.
-
(2000)
J. Virol.
, vol.74
, pp. 10589-10599
-
-
Reiser, J.1
Lai, Z.N.2
Zhang, X.Y.3
Brady, R.O.4
|