Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease

Journal of Neuroscience

Volumn 16, Issue 16, 1996, Pages 5168-5181

  Emerich, Dwaine F ^a   Lindner, Mark D ^a   Winn, Shelley R ^a   Chen, Er Yun ^b   Frydel, Beata R ^a   Kordower, Jeffrey H ^a  

^a CytoTherapeutics Inc   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

CNTF; fibroblasts; genetic modification; Huntington's disease; neurotrophic factor; polymer encapsulation; quinolinic acid; transplantation

Indexed keywords

CHOLINE ACETYLTRANSFERASE; CILIARY NEUROTROPHIC FACTOR; GLUTAMATE DECARBOXYLASE; NEUROPROTECTIVE AGENT; QUINOLINIC ACID; RECOMBINANT CILIARY NEUROTROPHIC FACTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR MODIFICATION; CONTROLLED STUDY; CORPUS STRIATUM; FIBROBLAST; HISTOPATHOLOGY; HUNTINGTON CHOREA; IMPLANTATION; INTRACEREBRAL DRUG ADMINISTRATION; MALE; NERVE DEGENERATION; NEUROTROPISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0029761786     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-16-05168.1996     Document Type: Article

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