-
1
-
-
0025224576
-
Nucleosomes: Regulators of transcription
-
Grunstein M: Nucleosomes: Regulators of transcription. Trends Genet 1990, 6:395-400.
-
(1990)
Trends Genet
, vol.6
, pp. 395-400
-
-
Grunstein, M.1
-
2
-
-
0017255219
-
Analysis of subunit organization in chicken erythrocyte chromatin
-
Shaw BR, Herman TM, Kovacic RT, Beaudreau GS, Van Holde KE: Analysis of subunit organization in chicken erythrocyte chromatin. Proc Natl Acad Sci USA 1976, 73:505-509.
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, pp. 505-509
-
-
Shaw, B.R.1
Herman, T.M.2
Kovacic, R.T.3
Beaudreau, G.S.4
Van Holde, K.E.5
-
3
-
-
0030798245
-
Histone acetylation in chromatin structure and transcription
-
Grunstein M: Histone acetylation in chromatin structure and transcription. Nature 1997, 389:349-352. This article provides an excellent review of the role of histone acetylation in gene transcription.
-
(1997)
Nature
, vol.389
, pp. 349-352
-
-
Grunstein, M.1
-
4
-
-
0032030770
-
Histone acetylation and transcriptional regulatory mechanisms
-
Struhl K: Histone acetylation and transcriptional regulatory mechanisms. Genes Dev 1998, 12:599-606. An excellent recent overview of the role of histone acetylation in gene transcription and exploration of three models by which histone modification affects the transcriptional activities of specific genes.
-
(1998)
Genes Dev
, vol.12
, pp. 599-606
-
-
Struhl, K.1
-
5
-
-
0030959244
-
Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression
-
Alland L, Muhle R, Hou H, Potes J, Chin L, Schreiber-Agus N, DePinho RA: Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature 1997, 387:49-55. This paper is one of the first to identify an interaction between human HDAC1 and the carboxy-terminal region of mSin3, and to show that this carboxy-terminal region is essential for Mxi1/mSin3-mediated suppression of cellular transformation.
-
(1997)
Nature
, vol.387
, pp. 49-55
-
-
Alland, L.1
Muhle, R.2
Hou, H.3
Potes, J.4
Chin, L.5
Schreiber-Agus, N.6
DePinho, R.A.7
-
6
-
-
0031007189
-
Histone deacetylase activity is required for full transcriptional repression by mSin3
-
Hassig CA, Fleischer TC, Billin AN, Schreiber SL, Ayer DE: Histone deacetylase activity is required for full transcriptional repression by mSin3. Cell 1997, 89:341-347. The authors show that mSin3A and HDAC1 associate in vivo and that the HDAC inhibitor, trapoxin, interferes with mSin3A-mediated transcriptional repression.
-
(1997)
Cell
, vol.89
, pp. 341-347
-
-
Hassig, C.A.1
Fleischer, T.C.2
Billin, A.N.3
Schreiber, S.L.4
Ayer, D.E.5
-
7
-
-
0032484989
-
Retinoblastoma protein recruits histone deacetylase to repress transcription
-
The authors show that Rb can associate with and recruit HDAC1 to the E2F-regulated cyclin E promoter. This interaction results in repression of cyclin E gene expression.
-
Brehm A, Miska EA, McCance DJ, Reid JL, Bannister AJ, Kouzarides T: Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 1998, 391:597-601. The authors show that Rb can associate with and recruit HDAC1 to the E2F-regulated cyclin E promoter. This interaction results in repression of cyclin E gene expression.
-
(1998)
Nature
, vol.391
, pp. 597-601
-
-
Brehm, A.1
Miska, E.A.2
McCance, D.J.3
Reid, J.L.4
Bannister, A.J.5
Kouzarides, T.6
-
8
-
-
0032484904
-
Retinoblastoma protein represses transcription by recruiting a histone deacetylase
-
Magnaghi-Jaulin L, Groisman R, Naguibneva I, Robin P, Lorain S, Le Villain JP, Troalen F, Trouche D, Harel-Bellan A: Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature 1998, 391:601-605. This paper, like [7••], also demonstrates a physical interaction between Rb and HDAC1. The HDAC sequence involved is an LXCXE motif similar to that used by viral transforming proteins to contact Rb. The authors suggest the Rb/HDAC1 complex is a key element in the control of cell proliferation and differentiation and is a likely target for transforming viruses.
-
(1998)
Nature
, vol.391
, pp. 601-605
-
-
Magnaghi-Jaulin, L.1
Groisman, R.2
Naguibneva, I.3
Robin, P.4
Lorain, S.5
Le Villain, J.P.6
Troalen, F.7
Trouche, D.8
Harel-Bellan, A.9
-
9
-
-
0029665857
-
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
-
Yang X-J, Ogryzko VV, Nishikawa J, Howard BH, Nakatani Y: A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 1996, 382:319-324.
-
(1996)
Nature
, vol.382
, pp. 319-324
-
-
Yang, X.-J.1
Ogryzko, V.V.2
Nishikawa, J.3
Howard, B.H.4
Nakatani, Y.5
-
10
-
-
0024829869
-
Histone acetylation decreased by estradiol in the MCF-7 human mammary cancer cell line
-
Pasqualini JR, Mercat P, Giambiagi N: Histone acetylation decreased by estradiol in the MCF-7 human mammary cancer cell line. Breast Cancer Res Treat 1989, 14:101-105.
-
(1989)
Breast Cancer Res Treat
, vol.14
, pp. 101-105
-
-
Pasqualini, J.R.1
Mercat, P.2
Giambiagi, N.3
-
11
-
-
0015098728
-
Epidemiology of cancer of the colon and rectum
-
Burkitt DP: Epidemiology of cancer of the colon and rectum. Cancer 1971, 28:3-13.
-
(1971)
Cancer
, vol.28
, pp. 3-13
-
-
Burkitt, D.P.1
-
12
-
-
0033590525
-
Dietry fiber and the risk of colorectal cancer and adenoma in women
-
Fuchs CS, Giovannucci EL, Colditz GA, Hunter DJ, Stampfer MJ, Rosner B. Speizer FE, Willet WC: Dietry fiber and the risk of colorectal cancer and adenoma in women. New Eng J Med 1999, 340:169-176.
-
(1999)
New Eng J Med
, vol.340
, pp. 169-176
-
-
Fuchs, C.S.1
Giovannucci, E.L.2
Colditz, G.A.3
Hunter, D.J.4
Stampfer, M.J.5
Rosner, B.6
Speizer, F.E.7
Willet, W.C.8
-
13
-
-
0030069148
-
Grist for the mill: Role of cereal fiber and calcium in prevention of colon cancer
-
Wargovich MJ, Levin B: Grist for the mill: Role of cereal fiber and calcium in prevention of colon cancer (editorial). J Natl Cancer Inst 1996, 88:67-69.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 67-69
-
-
Wargovich, M.J.1
Levin, B.2
-
14
-
-
0030810221
-
Wheat bran reduces tumor incidence in a rat model of colon cancer independent of effects on distal luminal butyrate concentrations
-
Zoran DL, Turner ND, Taddeo SS, Chapkin RS, Lupton JR: Wheat bran reduces tumor incidence in a rat model of colon cancer independent of effects on distal luminal butyrate concentrations. J Nutr 1997, 127:2217-2225. In a rat model of colon carcinogenesis (azoxymethane), the authors demonstrate that the less fermentable wheat bran fiber, as opposed to oats, was more protective against colon cancer development. The molar ratios of SCFAs and not the absolute butyrate concentration appeared to be most important in mediating this effect.
-
(1997)
J Nutr
, vol.127
, pp. 2217-2225
-
-
Zoran, D.L.1
Turner, N.D.2
Taddeo, S.S.3
Chapkin, R.S.4
Lupton, J.R.5
-
15
-
-
0029050647
-
Dietary fibers differ in their effects on large bowel epithelial proliferation and fecal fermentation-dependent events in rats
-
Folino M, McIntyre A, Young GP: Dietary fibers differ in their effects on large bowel epithelial proliferation and fecal fermentation-dependent events in rats. J Nutr 1995, 125:1521-1528.
-
(1995)
J Nutr
, vol.125
, pp. 1521-1528
-
-
Folino, M.1
McIntyre, A.2
Young, G.P.3
-
16
-
-
0024445622
-
Effects of wheat fiber and vitamin C and E on rectal polyps in patients with familial adenomatous polyposis
-
DeCosse JJ, Miller HH, Lesser ML: Effects of wheat fiber and vitamin C and E on rectal polyps in patients with familial adenomatous polyposis. J Natl Cancer Inst 1989, 81:1290-1297.
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 1290-1297
-
-
DeCosse, J.J.1
Miller, H.H.2
Lesser, M.L.3
-
17
-
-
0023743841
-
Short chain fatty acid distributions of enema samples from a sigmoidoscopy population: An association of high acetate and low butyrate ratios with denomatous polyps and colon cancer
-
Weaver GA, Krause JA, Miler TL, Wolin MJ: Short chain fatty acid distributions of enema samples from a sigmoidoscopy population: An association of high acetate and low butyrate ratios with denomatous polyps and colon cancer. Gut 1988, 29:1539-1543.
-
(1988)
Gut
, vol.29
, pp. 1539-1543
-
-
Weaver, G.A.1
Krause, J.A.2
Miler, T.L.3
Wolin, M.J.4
-
18
-
-
0026591463
-
Colonic fermentation and markers of colorectal-cancer risk
-
Kashtan H, Stern HS, Jenkins DJA, Jenkins AL, Thompson LU, Kay K, Marcon N, Minkin S, Bruce WR: Colonic fermentation and markers of colorectal-cancer risk. Am J Clin Nutr 1992, 55:723-728.
-
(1992)
Am J Clin Nutr
, vol.55
, pp. 723-728
-
-
Kashtan, H.1
Stern, H.S.2
Jenkins, D.J.A.3
Jenkins, A.L.4
Thompson, L.U.5
Kay, K.6
Marcon, N.7
Minkin, S.8
Bruce, W.R.9
-
19
-
-
0025819938
-
Colonic fermentation of dietary fibre to short chain fatty acids in patients with adenomatous polyps and colonic cancer
-
Clausen MR, Bonnen H, Mortensen PB: Colonic fermentation of dietary fibre to short chain fatty acids in patients with adenomatous polyps and colonic cancer. Gut 1991, 32:923-929.
-
(1991)
Gut
, vol.32
, pp. 923-929
-
-
Clausen, M.R.1
Bonnen, H.2
Mortensen, P.B.3
-
20
-
-
0029924943
-
Butyrate enemas in experimental colitis and protection against large bowel cancer in a rat model
-
D'Argenio G, Cosenza V, Cave MD, Iovino P, Valle ND, Lombardi G, Mazzacca G: Butyrate enemas in experimental colitis and protection against large bowel cancer in a rat model. Gastroenterology 1996, 110:1727-1734.
-
(1996)
Gastroenterology
, vol.110
, pp. 1727-1734
-
-
D'Argenio, G.1
Cosenza, V.2
Cave, M.D.3
Iovino, P.4
Valle, N.D.5
Lombardi, G.6
Mazzacca, G.7
-
21
-
-
0031963958
-
Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer
-
Medina V, Alfonso JJ, Alvarez-Arguelles H, Hernandez C, Gonzalez F. Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer. J Parenter Enteral Nutr 1998, 22:14-17. This study addresses directly the effect of butyrate on development of colon cancer in a rat model and shows that butyrate decreases the incidence of colon cancers developed and that some of the tumors were of a less aggressive phenotype.
-
(1998)
J Parenter Enteral Nutr
, vol.22
, pp. 14-17
-
-
Medina, V.1
Alfonso, J.J.2
Alvarez-Arguelles, H.3
Hernandez, C.4
Gonzalez, F.5
-
22
-
-
0029842032
-
Butyrate inhibits seeding and growth of colorectal metastases to the liver
-
Velazquez OC, Jabbar A, DeMatteo RP, Rombeau JL: Butyrate inhibits seeding and growth of colorectal metastases to the liver. Surgery 1996, 120:440-448.
-
(1996)
Surgery
, vol.120
, pp. 440-448
-
-
Velazquez, O.C.1
Jabbar, A.2
DeMatteo, R.P.3
Rombeau, J.L.4
-
23
-
-
0022978527
-
Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM1215)
-
Whitehead RH, Young GP, Bhathal PS: Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM1215). Gut 1986, 27:1457-1464.
-
(1986)
Gut
, vol.27
, pp. 1457-1464
-
-
Whitehead, R.H.1
Young, G.P.2
Bhathal, P.S.3
-
24
-
-
0030741385
-
Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors
-
McBain JA, Eastman A, Nobel CS, Mueller GC: Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors. Biochem Pharmacol 1997, 53:1357-1368.
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 1357-1368
-
-
McBain, J.A.1
Eastman, A.2
Nobel, C.S.3
Mueller, G.C.4
-
25
-
-
0031408419
-
Butyrate can act as a stimulator of growth or inducer of apoptosis in human colonic epithelial cell lines depending on the presence of alternative energy sources
-
Singh B, Halestrap AP, Paraskeva C: Butyrate can act as a stimulator of growth or inducer of apoptosis in human colonic epithelial cell lines depending on the presence of alternative energy sources. Carcinogenesis 1997, 18:1265-1270. This paper shows that, in the absence of glucose, low concentrations of butyrate stimulate growth of colon cancer cells; however, in the presence of glucose or at high concentrations of butyrate, apoptosis occurs.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1265-1270
-
-
Singh, B.1
Halestrap, A.P.2
Paraskeva, C.3
-
26
-
-
0017864644
-
The effect of sodium butyrate on histone modification
-
SeaLy L, Chalkley R: The effect of sodium butyrate on histone modification. Cell 1978, 14:115-121.
-
(1978)
Cell
, vol.14
, pp. 115-121
-
-
Sealy, L.1
Chalkley, R.2
-
27
-
-
0026495376
-
Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats
-
Boffa LC, Lupton JR, Mariani MR, Ceppi M, Newmark HL, Scalmati A, Lipkin M: Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats. Cancer Res 1992, 52:5906-5912.
-
(1992)
Cancer Res
, vol.52
, pp. 5906-5912
-
-
Boffa, L.C.1
Lupton, J.R.2
Mariani, M.R.3
Ceppi, M.4
Newmark, H.L.5
Scalmati, A.6
Lipkin, M.7
-
28
-
-
0032577235
-
A protein phosphatase is involved in the inhibition of histone deacetylation by sodium butyrate
-
Cuisset L, Tichonicky L, Delpech M: A protein phosphatase is involved in the inhibition of histone deacetylation by sodium butyrate. Biochem Biophys Res Commun 1998, 246:760-764. The authors show that specific serine-threonine phosphatase inhibitors blunted, to a varying degree, butyrate's effects on histone acetylation and implicate a role for a phosphatase of the PP1 type in inhibition of histone deacetylation by butyrate.
-
(1998)
Biochem Biophys Res Commun
, vol.246
, pp. 760-764
-
-
Cuisset, L.1
Tichonicky, L.2
Delpech, M.3
-
29
-
-
0027617675
-
Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells
-
Barnard JA, Warwick G: Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. Cell Growth Differ 1993, 4:495-501.
-
(1993)
Cell Growth Differ
, vol.4
, pp. 495-501
-
-
Barnard, J.A.1
Warwick, G.2
-
30
-
-
0023689244
-
Reversible arrest of proliferation of rat 3Y1 fibroblasts in both the G1 and G2 phases by trichostatin A
-
Yoshida M, Beppu T: Reversible arrest of proliferation of rat 3Y1 fibroblasts in both the G1 and G2 phases by trichostatin A. Exp Cell Res 1988, 177:122-131.
-
(1988)
Exp Cell Res
, vol.177
, pp. 122-131
-
-
Yoshida, M.1
Beppu, T.2
-
31
-
-
0032499756
-
WAF1 is required for butyrate-mediated growth inhibition of human colon cancer cells
-
WAF1 is required for butyrate-mediated growth inhibition of human colon cancer cells. Proc Natl Acad Sci USA 1998, 95:6791-6796. The authors show that p21 is induced in colon cancer cells via butyrate by a process which does not require new protein synthesis, is p53-independent, and at least partly involves histone hyperacetylation. This paper is the first to show that p21 is required for growth inhibition in colon cancer cells by butyrate.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6791-6796
-
-
Archer, S.1
Meng, S.2
Shei, A.3
Hodin, R.A.4
-
32
-
-
0030772026
-
Butyrate activates the WAF1/CIP1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line
-
Nakano K, Mizuno T, Sowa Y, Orita T, Yoshino T, Okuyama Y, Fujita T, Ohtani-Fujita N, Matsukawa Y, Tokino T et al.: Butyrate activates the WAF1/CIP1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line. J Biol Chem 1997, 272:22199-22206. This paper locates the p21 gene butyrate-response cis elements in WiDR colon cancer cells to two Sp1 sites at -82 and -69 relative to the transcriptional start site. The authors also show that a TATA element at -46 and two overlapping consensus Sp1 sites at -60 and -55 are essential for basal promoter activity.
-
(1997)
J Biol Chem
, vol.272
, pp. 22199-22206
-
-
Nakano, K.1
Mizuno, T.2
Sowa, Y.3
Orita, T.4
Yoshino, T.5
Okuyama, Y.6
Fujita, T.7
Ohtani-Fujita, N.8
Matsukawa, Y.9
Tokino, T.10
|