Transplantation of highly differentiated immortalized human hepatocytes to treat acute liver failure

Transplantation

Volumn 69, Issue 2, 2000, Pages 202-207

  Kobayashi, Naoya ^a   Miyazaki, Masahiro ^a   Fukaya, Kenichi ^a   Inoue, Yusuke ^a   Sakaguchi, Masakiyo ^a   Uemura, Tadahiro ^a   Noguchi, Hirofumi ^a   Kondo, Asami ^a   Tanaka, Noriaki ^a   Namba, Masayoshi ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS LARGE T ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTIFICIAL LIVER; CELL IMMORTALIZATION; CELL ISOLATION; CONFERENCE PAPER; HEPATIC ENCEPHALOPATHY; HUMAN; HUMAN TISSUE; HYPERAMMONEMIA; LIVER CELL; LIVER FAILURE; LIVER FUNCTION; LIVER RESECTION; MALE; METABOLIC RATE; NONHUMAN; PRIORITY JOURNAL; RAT; SIMIAN VIRUS 40; SURVIVAL RATE; TISSUE SPECIFICITY;

EID: 0034719370     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200001270-00002     Document Type: Conference Paper

References (29)

1. Sussman NL, Kelly JH. Artificial liver: a forthcoming attraction. Hepatology 1993; 17: 1163.
2. Rozga J Podesta L, LePage E, Morsiani E, Moscioni AD, Hoffman A, et al. A bioartificial liver to treat severe acute liver failure. Ann Surg 1994; 219: 538.
3. Shnyra A, Bocharov A, Bochkova N, Spirov V. Bioartificial liver using hepatocytes on Biosilon microcarriers: treatment of chemically induced acute hepatic failure in rats. Artif Organs 1991; 15: 189.
4. Sussman NL, Kelly JH. Improved liver function following treatment with an extracorporeal liver assist device. Artif Organs 1993; 17: 27.
5. Jauregui HO, Gann KL. Mammalian hepatocytes as a foundation for treatment in human liver failure. J Cell Biochem 1991; 45: 359.
6. Yarmush ML, Dunn JC, Tompkins RG. Assessment of artificial liver support technology. Cell Transplantation 1992; 1: 323.
7. Nyberg SL, Shatford RA, Hu WS, Payne WD, Cerra FB. Hepatocyte culture systems for artificial liver support: implication to critical care medicine. Crit Care Med 1992; 20: 1157.
8. Knowles BB, Howe CC, Aden DP. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 1980; 209: 497.
9. Zeindl-Eberhart E, Rabes HM. Variant protein patterns in hepatomas and transformed liver cell lines as determined by high resolution two-dimensional gel electrophoresis (2DE). Carcinogenesis 1992; 13: 1177.
10. Demetriou AA, Reisner A, Sanchez J, Levenson SM, Moscioni AD, Chowdhury JR. Transplantation of microcarrier-attached hepatocytes into 90% partially hepatectomized rats. Hepatology 1988; 8: 1069.
11. Emond J, Capron-Laudereau M, Meriggi F, Bernuau J, Reynes M, Houssin RD. Extent of hepatectomy in the rat: evaluation of basal conditions and effect of therapy. Eur Surg Res 1989; 21: 251.
12. Bures J, Buresova O, Huston JP. Innate and motivated behavior. In: Techniques and basic experiments for the study of brain and behavior. New York: Elsevier, 1976: 37.
13. Van de Vyver FL, Giuliano RA, Paulus GJ. Hemoperfusion-hemodialysis ineffective for paraquat removal in life-threatening poisoning? Clin Toxicol 1985; 23: 117.
14. Hughes R, Williams R. Clinical experience with charcoal and resin hemoperfusion. Semin Liver Dis 1986; 6: 164-173.
15. O'Grady JG, Gimson AE, O'Brein CJ, Pucknell A, Hughes RD, Williams R. Controlled trials of charcoal hemoperfusion and prognostic factors in fulminant hepatic failure. Gastroenterology 1988; 94: 1186.
16. Takahashi M, Ishikura H, Takahashi C, Nakajima Y, Matsushita M, Matue H, et al. Immunologic considerations in the use of cultured porcine hepatocytes as a hybrid artificial liver: anti-porcine hepatocyte human serum. ASAIO J 1993; 39: M242.
17. Miyazaki M, Mihara K, Bai L, Kano Y, Tsuboi S, Endo A, et al. Immortalization of epithelial-like cells from human liver tissue with SV40 T-antigen gene. Exp Cell Res 1993; 206: 27.
18. Namba M, Nishitani K, Kimoto T, Sato K. In: Chadwick KH, Seymour C, Barnhart B, eds. Cell transformation and radiation-induced cancer., Bristol/New York: Adam Hilger, 1989: 67.
19. Wang XD, Soltesz V, Andersson R, Bengmark S. Bacterial translocation in acute liver failure induced by ninety percent hepatectomy in the rat. Br J Surg 1993; 80: 66.
20. Woods RJ, Fuller BJ, Attenburrow VD, Nutt LH, Hobbs KEF. Functional assessment of hepatocytes after transplantation into rat spleen. Transplantation 1982; 33: 123.
21. Cuervas-Mons V, Cienfuegos JA, Maganto P. Long-term evaluation of isolated syngeneic hepatocytes transplanted into the normal rat spleen by Tc-99M-HIDA scintigraphy. Transplantation 1985; 39: 87.
22. Panis Y, Puts JP, Ballet J, Ballet F, Penin E, Delelo R. The isolated perfused spleen: an original method for studying the function of hepatocytes transplanted into the spleen. Transplantation 1990; 49: 756.
23. Naganto P, Traber PG, Rusnell C, Dobbins WO, Keren D, Gumucio JJ. Long-term maintenance of the adult pattern of liver-specific expression for P-450b, P-450e, albumin and a-fetoprotein genes in intrasplenically transplanted hepatocytes. Hepatology 1990; 11: 585.
24. Strom SC, Fisher RA, Thompson MT, Sanya, AJ, Cole PE, Ham JM, et al. Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure. Transplantation 1997; 63: 559.
25. Gebhardt R, Jirtle R, Moorman AFM, Lamers WH, Michalopoulos G. Induction of glutamine synthetase and transient coexpression with carbamoylphosphate synthetase in hepatocytes transplanted into fat pads of syngeneic hosts. Histochemistry 1989; 92: 337.
26. Wagenaar GTM, Chamuleau RAFM, de Haan JG. Experimental evidence that the physiological position of the liver within the circulation is not a major determination of zonation of gene expression. Hepatology 1993; 18: 1144.
27. Chen L, Davis GJ, Crabb DW, Lumeng L. Intrasplenic transplantation of isolated periportal and perivenous hepatocytes as a long-term system to study liver-specific gene expression. Hepatology 1994; 19: 989.
28. Westerman KA, Leboulch P. Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination. Proc Natl Acad Sci USA 1996; 93: 8971.
29. Schumacher IK, Okamoto T, Kim BH, Chowdhury NR, Chowdhury JR, Fox IJ. Transplantation of conditionally immortalized hepatocytes to treat hepatic encephalopathy. Hepatology 1996; 24: 337.