Comparison of different hepatocyte cell lines for use in a hybrid artificial liver model

Cytotechnology

Volumn 24, Issue 1, 1997, Pages 39-45

  Takagi, M ^a   Fukuda, N ^a   Yoshida, T ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

artificial liver; gluconeogenesis; hepatocyte cell line; microcarrier culture; porous beads; ureogenesis

Indexed keywords

EID: 0031005257     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007927906986     Document Type: Article

References (15)

1. Aden DP, Fogel A, Plotkin S, Damjanov I and Knowles BB (1979) Controlled synthesis of HBsAg in a differentiated human liver carcinima-derived cell line. Nature 282: 615-616.
2. Doi I, Namba M, Sato J (1975) Establishment and some biological characteristics of human hepatoma cell lines. Gann 66: 385-392.
3. Ijima H, Matsushita T and Funatsu K (1993) Development of a hybrid type artificial liver using PUF/spheroid culture system of adult hepetocytes. Jpn. J. Artif. Organs 22: 171-176.
4. Kasai S, Sawa M, Tomita I, Hashimoto M, Jiang B, Hirai S, Kakisaka A, Yamamoto T, Mito M and Inoue M (1993) Metabolic activities of multiporous cellulose microcarrier attached hepatocytes. Jpn. J. Artif. Organs 22: 159-163.
5. Macnab GM, Alexander JJ, Lecatsas G, Bey EM and Urbanowicz JM (1976) Hepatitis B surface antigen produced by a human hepatoma cell line. Br. J. Cancer 34: 509-515.
6. Miyoshi H, Yanagi H, Furukawa K and Ohshima N (1993) Continuous culture of hepatocytes under different medium conditions using a packed-bed reactor loaded with porous resins. Jpn. J. Artif. Organs 22: 147-152.
7. Nakabayashi H, Taketa K, Miyano K, Yamane T and Sato J (1982) Growth of human hepatoma cell lines with differentiated functions in chemically defined medium. Cancer Res. 42: 3858-3863.
8. Nyberg SL, Shatford RA, Peshwa MV, White HG, Cerra FB ans Hu W-S (1993) Evaluation of a hepatocyte.entrapment hollow fiber reactor: A potential bioartificial liver. Biotech. Bioeng. 41: 194-203.
9. Park S and Stephanopoulos G (1993) Packed bed bioreactor with porous ceramic beads for animal cell culture. Biotech. Bioeng. 41: 25-34. 34.
10. Razga J, Holzman MD, Ro M-S, Griffin DW, Neuzil DF, Giorgio T, Moscioni AD and Demetriou AA (1993) Development of a hyvrid bioartificial liver. Annals. Surgery 217: 502-511.
11. Sakai Y and Suzuki M (1994) Functional expressions by hepatocyte spheroids entrapped in collagen gel in hallow fiber modules Jpn. J. Artif. Organs 23: 473-478.
12. Sanford KK, Earle WR, Evans VJ, Waltz HK and Shannon JE (1959) The measurement of proliferation in tissue cultures by enumeration of cell nuclei. J. Nat. Cane. Inst. 11: 773-795.
13. Sussman NL and Kelly JH (1993) Improved liver function following treatment with an extracorporeal liver assist device. Artif. Organs 17: 27-30.
14. Takagi M, Shirokaze J, Oishi K, Otsubo K, Yamamoto K, Yoshida N and Fujimatsu I (1994) Production of S- (+)-ibuprofen with high optical purity from a nitrile compounds by cells immobilized on cellulose porous beads. J. Ferment. Bioeng. 78: 191-193.
15. Takeshita K, Ishibashi H, Suzuki M, Tobe S, Takei Y, Kishida A, Akaike T and Kodama M (1993) High cell-density culture system of hepatocytes entrapped in a three dimensional collagen-gel matrix using a hollow fiber module. Jpn. J. Artif. Organs 22: 153-158.