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Volumn 126, Issue 6, 1999, Pages 1136-1143

Activation of protein kinase B induced by H2O2 and heat shock through distinct mechanisms dependent and independent of phosphatidylinositol 3- kinase

Author keywords

Heat shock; Hydrogen peroxide (H2O2); Phosphatidylinositol 3 kinase; Pleckstrin homology domain; Protein kinase B

Indexed keywords

GROWTH FACTOR; HYDROGEN PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4 BISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHOLIPID; PLECKSTRIN; PROTEIN KINASE B; WORTMANNIN;

EID: 0033375906     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022559     Document Type: Article
Times cited : (42)

References (36)
  • 1
    • 0031053360 scopus 로고    scopus 로고
    • Akt signaling: Linking membrane events to life and death decisions
    • Hemmings, B.A. (1997) Akt signaling: linking membrane events to life and death decisions. Science 275, 628-630
    • (1997) Science , vol.275 , pp. 628-630
    • Hemmings, B.A.1
  • 2
    • 0032189381 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
    • Coffer, P.J., Jin, J., and Woodgett, J.R. (1998) Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem. J. 335, 1-13
    • (1998) Biochem. J. , vol.335 , pp. 1-13
    • Coffer, P.J.1    Jin, J.2    Woodgett, J.R.3
  • 3
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke, T.F., Yang, S.I., Chan, T.O., Datta, K., Kazlauskaus, A., Morison, D.K., Kaplan, D.R., and Tsichlis, P.N. (1995) The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81, 727-736
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.I.2    Chan, T.O.3    Datta, K.4    Kazlauskaus, A.5    Morison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 4
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering, B.M.T. and Coffer, P.J. (1995) Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376, 599-602
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.T.1    Coffer, P.J.2
  • 5
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross, D.A.E., Alessi, D.R., Cohen, P., Andjelkovic, M., and Hemmings, B.A. (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378, 785-789
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovic, M.4    Hemmings, B.A.5
  • 6
    • 0029143388 scopus 로고
    • Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing Ser/Thr kinase
    • Kohn, A.D., Kovacina, K.S., and Roth, R.A. (1995) Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing Ser/Thr kinase. EMBO J. 14, 4288-4295
    • (1995) EMBO J. , vol.14 , pp. 4288-4295
    • Kohn, A.D.1    Kovacina, K.S.2    Roth, R.A.3
  • 7
    • 0031015986 scopus 로고    scopus 로고
    • A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin ho-mology domain
    • Klippel, A., Kavanaugh, W.M., Pot, D., and Williams, L.T. (1997) A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin ho-mology domain. Mol. Cell. Biol. 17, 338-344
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 338-344
    • Klippel, A.1    Kavanaugh, W.M.2    Pot, D.3    Williams, L.T.4
  • 8
    • 0031039024 scopus 로고    scopus 로고
    • Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
    • Franke, T.F., Kaplan, D.R., Cantley, L.C., and Toker, A. (1997) Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science 275, 665-668
    • (1997) Science , vol.275 , pp. 665-668
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3    Toker, A.4
  • 9
    • 0030991386 scopus 로고    scopus 로고
    • High affinity binding of inositol phosphates and phosphoinositides to the pleckstrin homology domain of RAC/protein kinase B and their influence on kinase activity
    • Frech, M., Andjelkovic, M., Ingley, E., Reddy, K.K., Falck, J.R., and Hemmings, B.A. (1997) High affinity binding of inositol phosphates and phosphoinositides to the pleckstrin homology domain of RAC/protein kinase B and their influence on kinase activity. J. Biol. Chem. 272, 8474-8481
    • (1997) J. Biol. Chem. , vol.272 , pp. 8474-8481
    • Frech, M.1    Andjelkovic, M.2    Ingley, E.3    Reddy, K.K.4    Falck, J.R.5    Hemmings, B.A.6
  • 10
    • 0029810181 scopus 로고    scopus 로고
    • Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation
    • Kohn, A.D., Takeuchi, F., and Roth, R.A. (1996) Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation. J. Biol. Chem. 271, 21920-21926
    • (1996) J. Biol. Chem. , vol.271 , pp. 21920-21926
    • Kohn, A.D.1    Takeuchi, F.2    Roth, R.A.3
  • 11
    • 0029942186 scopus 로고    scopus 로고
    • Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
    • Andjelkovic, M., Jakubowicz, T., Cron, P., Ming, X.F., Han, J.W., and Hemmings, B.A. (1997) Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors. Proc. Natl. Acad. Sci. USA 93, 5699-5704
    • (1997) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5699-5704
    • Andjelkovic, M.1    Jakubowicz, T.2    Cron, P.3    Ming, X.F.4    Han, J.W.5    Hemmings, B.A.6
  • 13
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
    • Alessi, D.R., James, S.R., Downes, C.P., Holmes, A.B., Gaffney, P.R.J., Reese, C.B., and Cohen, P. (1997) Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα. Curr. Biol. 7, 261-269
    • (1997) Curr. Biol. , vol.7 , pp. 261-269
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.J.5    Reese, C.B.6    Cohen, P.7
  • 17
    • 0029821721 scopus 로고    scopus 로고
    • Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase
    • Konishi, H., Matsuzaki, H., Tanaka, M., Ono, Y., Tokunaga, C., Kuroda, S., and Kikkawa, U. (1996) Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase. Proc. Natl. Acad. Sci. USA 93, 7639-7643
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7639-7643
    • Konishi, H.1    Matsuzaki, H.2    Tanaka, M.3    Ono, Y.4    Tokunaga, C.5    Kuroda, S.6    Kikkawa, U.7
  • 18
    • 0032533546 scopus 로고    scopus 로고
    • 2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2
    • 2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2. Biochem. J. 336, 241-246
    • (1998) Biochem. J. , vol.336 , pp. 241-246
    • Shaw, M.1    Cohen, P.2    Alessi, D.R.3
  • 19
    • 0033537830 scopus 로고    scopus 로고
    • Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation
    • Tirosh, A., Potashnik, R., Bashan, N., and Rudich, A. (1999) Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation. J. Biol. Chem. 274, 10595-10602
    • (1999) J. Biol. Chem. , vol.274 , pp. 10595-10602
    • Tirosh, A.1    Potashnik, R.2    Bashan, N.3    Rudich, A.4
  • 20
    • 0030680132 scopus 로고    scopus 로고
    • Heat shock activates c-Src tyrosine kinases and phosphatidylinositol 3-kinase in NIH3T3 fibroblasts
    • Lin, R.Z., Hu, Z.W., Chin, J.H., and Hoffman, B.B. (1997) Heat shock activates c-Src tyrosine kinases and phosphatidylinositol 3-kinase in NIH3T3 fibroblasts. J. Biol. Chem. 272, 31196-31202
    • (1997) J. Biol. Chem. , vol.272 , pp. 31196-31202
    • Lin, R.Z.1    Hu, Z.W.2    Chin, J.H.3    Hoffman, B.B.4
  • 21
    • 0030785701 scopus 로고    scopus 로고
    • Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27
    • Konishi, H., Matsuzaki, H., Tanaka, M., Takemura, Y., Kuroda, S., Ono, Y., and Kikkawa, U. (1997) Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27. FEBS Lett. 410, 493-498
    • (1997) FEBS Lett. , vol.410 , pp. 493-498
    • Konishi, H.1    Matsuzaki, H.2    Tanaka, M.3    Takemura, Y.4    Kuroda, S.5    Ono, Y.6    Kikkawa, U.7
  • 22
    • 0033529675 scopus 로고    scopus 로고
    • Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells
    • Ushio-Fukai, M., Alexander, R.W., Akers, M., Yin, Q., Fujio, Y., Walsh, K., and Griendling, K.K. (1999) Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells. J. Biol. Chem. 274, 22699-22704
    • (1999) J. Biol. Chem. , vol.274 , pp. 22699-22704
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3    Yin, Q.4    Fujio, Y.5    Walsh, K.6    Griendling, K.K.7
  • 24
    • 0027985080 scopus 로고
    • Molecular cloning of rat RAC protein kinase α and β and their association with protein kinase C ζ
    • Konishi, H., Shinomura, T., Kuroda, S., Ono, Y., and Kikkawa, U. (1994) Molecular cloning of rat RAC protein kinase α and β and their association with protein kinase C ζ. Biochem. Biophys. Res. Commun. 205, 817-825
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 817-825
    • Konishi, H.1    Shinomura, T.2    Kuroda, S.3    Ono, Y.4    Kikkawa, U.5
  • 25
    • 0025882091 scopus 로고
    • Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily
    • Jones, F.F., Jakubowicz, T., Pitossi, F.J., Maurer, F., and Hemmings, B.A. (1991) Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. Proc. Natl. Acad. Sci. USA 88, 4171-4175
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4171-4175
    • Jones, F.F.1    Jakubowicz, T.2    Pitossi, F.J.3    Maurer, F.4    Hemmings, B.A.5
  • 26
    • 0032498791 scopus 로고    scopus 로고
    • MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase
    • Suzuki, A., Sugiyama, Y., Hayashi, Y., Nyu-i, N., Yoshida, M., Nonaka, I., Ishiura, S., Arahata, K., and Ohno, S. (1998) MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase. J. Cell Biol. 140, 1113-1124
    • (1998) J. Cell Biol. , vol.140 , pp. 1113-1124
    • Suzuki, A.1    Sugiyama, Y.2    Hayashi, Y.3    Nyu-i, N.4    Yoshida, M.5    Nonaka, I.6    Ishiura, S.7    Arahata, K.8    Ohno, S.9
  • 27
    • 0024382926 scopus 로고
    • Phosphatidylinositol kinase type I activity associates with various oncogene products
    • Fukui, Y., Kornbluth, S., Jong, S.-M., Wang, L.-H., and Hanafusa, H. (1989) Phosphatidylinositol kinase type I activity associates with various oncogene products. Oncogene Res. 4, 283-292
    • (1989) Oncogene Res. , vol.4 , pp. 283-292
    • Fukui, Y.1    Kornbluth, S.2    Jong, S.-M.3    Wang, L.-H.4    Hanafusa, H.5
  • 28
    • 0030992837 scopus 로고    scopus 로고
    • Signalling through the lipid products of phosphoinositide-3-OH kinase
    • Toker, A. and Cantley, L.C. (1997) Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature 387, 673-676
    • (1997) Nature , vol.387 , pp. 673-676
    • Toker, A.1    Cantley, L.C.2
  • 32
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/ AKT by the integrin-lmked kinase
    • Delcommenne, M., Tan, C., Gray, V., Rue, L., Woodgett, J., and Dedhar, S. (1998) Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/ AKT by the integrin-lmked kinase. Proc. Natl. Acad. Sci. USA 95, 11211-11216
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 11211-11216
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Rue, L.4    Woodgett, J.5    Dedhar, S.6
  • 33
    • 0033594480 scopus 로고    scopus 로고
    • PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2
    • Balendran, A., Casamayor, A., Deak, M., Paterson, A., Gaffney, P., Currie, R., Downes, C.P., and Alessi, D.R. (1999) PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2. Curr. Biol. 9, 393-404
    • (1999) Curr. Biol. , vol.9 , pp. 393-404
    • Balendran, A.1    Casamayor, A.2    Deak, M.3    Paterson, A.4    Gaffney, P.5    Currie, R.6    Downes, C.P.7    Alessi, D.R.8
  • 34
    • 16944366762 scopus 로고    scopus 로고
    • Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and β-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms
    • Moule, S.K., Welsh, G.I., Edgell, N.J., Foulstone, E.J., Proud, C.G., and Denton, R.M. (1997) Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and β-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms. J. Biol. Chem. 272, 7713-7719
    • (1997) J. Biol. Chem. , vol.272 , pp. 7713-7719
    • Moule, S.K.1    Welsh, G.I.2    Edgell, N.J.3    Foulstone, E.J.4    Proud, C.G.5    Denton, R.M.6
  • 35
    • 0032997270 scopus 로고    scopus 로고
    • Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase
    • Filippa, N., Sable, C.L., Filloux, C., Hemmings, B., and Van Obberghen, E. (1999) Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase. Mol. Cell. Biol. 19, 4989-5000
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4989-5000
    • Filippa, N.1    Sable, C.L.2    Filloux, C.3    Hemmings, B.4    Van Obberghen, E.5
  • 36
    • 0028346451 scopus 로고
    • Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27
    • Kato, K., Hasegawa, K., Goto, S., and Inaguma, Y. (1994) Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27. J. Biol. Chem. 269, 11274-11278
    • (1994) J. Biol. Chem. , vol.269 , pp. 11274-11278
    • Kato, K.1    Hasegawa, K.2    Goto, S.3    Inaguma, Y.4


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