A natural antibody missing a cysteine in V(H): Consequences for thermodynamic stability and folding

Journal of Molecular Biology

Volumn 265, Issue 2, 1997, Pages 161-172

  Proba, Karl ^a   Honegger, Annemarie ^a   Plückthun, Andreas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Antibodies; Disulfide bond; Protein folding; scFv fragment; Stability

Indexed keywords

ANTIBODY; CYSTEINE; GLUTATHIONE; IMMUNOGLOBULIN HEAVY CHAIN; TYROSINE;

AFFINITY CHROMATOGRAPHY; ANTIBODY STRUCTURE; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; IMMUNOGLOBULIN VARIABLE REGION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STABILITY; THERMODYNAMICS;

ESCHERICHIA COLI;

EID: 0031575401     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0726     Document Type: Article

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