-
1
-
-
28244440935
-
-
For recent reviews of the metathesis reaction, see: (a) Armstrong, S. K. J. Chem. Soc., Perkin Trans. 1 1998, 371; (b) Grubbs, R. H.; Chang, S. Tetrahedron 1998, 54, 4413; (c) Tetrahedron symposium in print: Snapper, M. L.; Hoveyda, A. H. Eds.; 1999, 55, 8141; (d) Alkene Metathesis in Organic Synthesis; Top. Organomet. Chem. 1998, 1, Furstner, A. Ed.; (e) Blechert, S. Pure Appl. Chem. 1999, 8, 1393; (f) Furstner, A. Angew. Chem., Int. Ed. Engl. 2000, 39, 3012; (g) Trnka, T. M.; Grubbs, R. H. Acc. Chem. Res. 2001, 34, 18.
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(1998)
J. Chem. Soc., Perkin Trans. 1
, pp. 371
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Armstrong, S.K.1
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2
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0032580376
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For recent reviews of the metathesis reaction, see: (a) Armstrong, S. K. J. Chem. Soc., Perkin Trans. 1 1998, 371; (b) Grubbs, R. H.; Chang, S. Tetrahedron 1998, 54, 4413; (c) Tetrahedron symposium in print: Snapper, M. L.; Hoveyda, A. H. Eds.; 1999, 55, 8141; (d) Alkene Metathesis in Organic Synthesis; Top. Organomet. Chem. 1998, 1, Furstner, A. Ed.; (e) Blechert, S. Pure Appl. Chem. 1999, 8, 1393; (f) Furstner, A. Angew. Chem., Int. Ed. Engl. 2000, 39, 3012; (g) Trnka, T. M.; Grubbs, R. H. Acc. Chem. Res. 2001, 34, 18.
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(1998)
Tetrahedron
, vol.54
, pp. 4413
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Grubbs, R.H.1
Chang, S.2
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3
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0001082973
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-
For recent reviews of the metathesis reaction, see: (a) Armstrong, S. K. J. Chem. Soc., Perkin Trans. 1 1998, 371; (b) Grubbs, R. H.; Chang, S. Tetrahedron 1998, 54, 4413; (c) Tetrahedron symposium in print: Snapper, M. L.; Hoveyda, A. H. Eds.; 1999, 55, 8141; (d) Alkene Metathesis in Organic Synthesis; Top. Organomet. Chem. 1998, 1, Furstner, A. Ed.; (e) Blechert, S. Pure Appl. Chem. 1999, 8, 1393; (f) Furstner, A. Angew. Chem., Int. Ed. Engl. 2000, 39, 3012; (g) Trnka, T. M.; Grubbs, R. H. Acc. Chem. Res. 2001, 34, 18.
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(1999)
Tetrahedron Symposium in Print
, vol.55
, pp. 8141
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Snapper, M.L.1
Hoveyda, A.H.2
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4
-
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0003464699
-
-
For recent reviews of the metathesis reaction, see: (a) Armstrong, S. K. J. Chem. Soc., Perkin Trans. 1 1998, 371; (b) Grubbs, R. H.; Chang, S. Tetrahedron 1998, 54, 4413; (c) Tetrahedron symposium in print: Snapper, M. L.; Hoveyda, A. H. Eds.; 1999, 55, 8141; (d) Alkene Metathesis in Organic Synthesis; Top. Organomet. Chem. 1998, 1, Furstner, A. Ed.; (e) Blechert, S. Pure Appl. Chem. 1999, 8, 1393; (f) Furstner, A. Angew. Chem., Int. Ed. Engl. 2000, 39, 3012; (g) Trnka, T. M.; Grubbs, R. H. Acc. Chem. Res. 2001, 34, 18.
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(1998)
Alkene Metathesis in Organic Synthesis; Top. Organomet. Chem.
, pp. 1
-
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Furstner, A.1
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5
-
-
0000894823
-
-
For recent reviews of the metathesis reaction, see: (a) Armstrong, S. K. J. Chem. Soc., Perkin Trans. 1 1998, 371; (b) Grubbs, R. H.; Chang, S. Tetrahedron 1998, 54, 4413; (c) Tetrahedron symposium in print: Snapper, M. L.; Hoveyda, A. H. Eds.; 1999, 55, 8141; (d) Alkene Metathesis in Organic Synthesis; Top. Organomet. Chem. 1998, 1, Furstner, A. Ed.; (e) Blechert, S. Pure Appl. Chem. 1999, 8, 1393; (f) Furstner, A. Angew. Chem., Int. Ed. Engl. 2000, 39, 3012; (g) Trnka, T. M.; Grubbs, R. H. Acc. Chem. Res. 2001, 34, 18.
-
(1999)
Pure Appl. Chem.
, vol.8
, pp. 1393
-
-
Blechert, S.1
-
6
-
-
33751304593
-
-
For recent reviews of the metathesis reaction, see: (a) Armstrong, S. K. J. Chem. Soc., Perkin Trans. 1 1998, 371; (b) Grubbs, R. H.; Chang, S. Tetrahedron 1998, 54, 4413; (c) Tetrahedron symposium in print: Snapper, M. L.; Hoveyda, A. H. Eds.; 1999, 55, 8141; (d) Alkene Metathesis in Organic Synthesis; Top. Organomet. Chem. 1998, 1, Furstner, A. Ed.; (e) Blechert, S. Pure Appl. Chem. 1999, 8, 1393; (f) Furstner, A. Angew. Chem., Int. Ed. Engl. 2000, 39, 3012; (g) Trnka, T. M.; Grubbs, R. H. Acc. Chem. Res. 2001, 34, 18.
-
(2000)
Angew. Chem., Int. Ed. Engl.
, vol.39
, pp. 3012
-
-
Furstner, A.1
-
7
-
-
0034746687
-
-
For recent reviews of the metathesis reaction, see: (a) Armstrong, S. K. J. Chem. Soc., Perkin Trans. 1 1998, 371; (b) Grubbs, R. H.; Chang, S. Tetrahedron 1998, 54, 4413; (c) Tetrahedron symposium in print: Snapper, M. L.; Hoveyda, A. H. Eds.; 1999, 55, 8141; (d) Alkene Metathesis in Organic Synthesis; Top. Organomet. Chem. 1998, 1, Furstner, A. Ed.; (e) Blechert, S. Pure Appl. Chem. 1999, 8, 1393; (f) Furstner, A. Angew. Chem., Int. Ed. Engl. 2000, 39, 3012; (g) Trnka, T. M.; Grubbs, R. H. Acc. Chem. Res. 2001, 34, 18.
-
(2001)
Acc. Chem. Res.
, vol.34
, pp. 18
-
-
Trnka, T.M.1
Grubbs, R.H.2
-
9
-
-
0034697870
-
-
Bassingdale M.J., Edwards A.S., Hamley P., Adams H., Harrity J.P.A. Chem. Commun. 2000;1035.
-
(2000)
Chem. Commun.
, pp. 1035
-
-
Bassingdale, M.J.1
Edwards, A.S.2
Hamley, P.3
Adams, H.4
Harrity, J.P.A.5
-
16
-
-
0037190847
-
-
Wybrow R.A.J., Johnson L.A., Auffray B., Moran W.J., Adams H., Harrity J.P.A. Tetrahedron Lett. 43:2002;7851.
-
(2002)
Tetrahedron Lett.
, vol.43
, pp. 7851
-
-
Wybrow, R.A.J.1
Johnson, L.A.2
Auffray, B.3
Moran, W.J.4
Adams, H.5
Harrity, J.P.A.6
-
23
-
-
0029884246
-
-
For ring opening, double ring-closing strategies see, inter alia: (a) Zuercher, W. J.; Hashimoto, M.; Grubbs, R. H. J. Am. Chem. Soc. 1996, 118, 6634; (b) Zuercher, W. J.; Scholl, M.; Grubbs, R. H. J. Org. Chem. 1998, 63, 4291; (c) Burke, S. D.; Quinn, K. J.; Chen, V. J. J. Org. Chem. 1998, 63, 8628; (d) Nicolaou, K. C.; Vega, J. A.; Vassilikogiannakis, G. Angew. Chem., Int. Ed. Engl. 2001, 40, 4441.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 6634
-
-
Zuercher, W.J.1
Hashimoto, M.2
Grubbs, R.H.3
-
24
-
-
0001117364
-
-
For ring opening, double ring-closing strategies see, inter alia: (a) Zuercher, W. J.; Hashimoto, M.; Grubbs, R. H. J. Am. Chem. Soc. 1996, 118, 6634; (b) Zuercher, W. J.; Scholl, M.; Grubbs, R. H. J. Org. Chem. 1998, 63, 4291; (c) Burke, S. D.; Quinn, K. J.; Chen, V. J. J. Org. Chem. 1998, 63, 8628; (d) Nicolaou, K. C.; Vega, J. A.; Vassilikogiannakis, G. Angew. Chem., Int. Ed. Engl. 2001, 40, 4441.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 4291
-
-
Zuercher, W.J.1
Scholl, M.2
Grubbs, R.H.3
-
25
-
-
0000504201
-
-
For ring opening, double ring-closing strategies see, inter alia: (a) Zuercher, W. J.; Hashimoto, M.; Grubbs, R. H. J. Am. Chem. Soc. 1996, 118, 6634; (b) Zuercher, W. J.; Scholl, M.; Grubbs, R. H. J. Org. Chem. 1998, 63, 4291; (c) Burke, S. D.; Quinn, K. J.; Chen, V. J. J. Org. Chem. 1998, 63, 8628; (d) Nicolaou, K. C.; Vega, J. A.; Vassilikogiannakis, G. Angew. Chem., Int. Ed. Engl. 2001, 40, 4441.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 8628
-
-
Burke, S.D.1
Quinn, K.J.2
Chen, V.J.3
-
26
-
-
0035803694
-
-
For ring opening, double ring-closing strategies see, inter alia: (a) Zuercher, W. J.; Hashimoto, M.; Grubbs, R. H. J. Am. Chem. Soc. 1996, 118, 6634; (b) Zuercher, W. J.; Scholl, M.; Grubbs, R. H. J. Org. Chem. 1998, 63, 4291; (c) Burke, S. D.; Quinn, K. J.; Chen, V. J. J. Org. Chem. 1998, 63, 8628; (d) Nicolaou, K. C.; Vega, J. A.; Vassilikogiannakis, G. Angew. Chem., Int. Ed. Engl. 2001, 40, 4441.
-
(2001)
Angew. Chem., Int. Ed. Engl.
, vol.40
, pp. 4441
-
-
Nicolaou, K.C.1
Vega, J.A.2
Vassilikogiannakis, G.3
-
27
-
-
0001354464
-
-
For tandem RCM reaction of dienynes see, inter alia: (a) Kim, S.-H.; Zuercher, W. J.; Bowden, N. B.; Grubbs, R. H. J. Org. Chem. 1996, 61, 1073; (b) Renaud, J.; Graf, C.-D.; Oberer, L. Angew. Chem., Int. Ed. Engl. 2000, 39, 3101; (c) Choi, T.-L.; Grubbs, R. H. Chem. Commun. 2001, 2648; (d) Boyer, F.-D.; Hanna, I. Tetrahedron Lett. 2002, 43, 7469.
-
(1996)
J. Org. Chem.
, vol.61
, pp. 1073
-
-
Kim, S.-H.1
Zuercher, W.J.2
Bowden, N.B.3
Grubbs, R.H.4
-
28
-
-
0034283391
-
-
For tandem RCM reaction of dienynes see, inter alia: (a) Kim, S.-H.; Zuercher, W. J.; Bowden, N. B.; Grubbs, R. H. J. Org. Chem. 1996, 61, 1073; (b) Renaud, J.; Graf, C.-D.; Oberer, L. Angew. Chem., Int. Ed. Engl. 2000, 39, 3101; (c) Choi, T.-L.; Grubbs, R. H. Chem. Commun. 2001, 2648; (d) Boyer, F.-D.; Hanna, I. Tetrahedron Lett. 2002, 43, 7469.
-
(2000)
Angew. Chem., Int. Ed. Engl.
, vol.39
, pp. 3101
-
-
Renaud, J.1
Graf, C.-D.2
Oberer, L.3
-
29
-
-
0035930791
-
-
For tandem RCM reaction of dienynes see, inter alia: (a) Kim, S.-H.; Zuercher, W. J.; Bowden, N. B.; Grubbs, R. H. J. Org. Chem. 1996, 61, 1073; (b) Renaud, J.; Graf, C.-D.; Oberer, L. Angew. Chem., Int. Ed. Engl. 2000, 39, 3101; (c) Choi, T.-L.; Grubbs, R. H. Chem. Commun. 2001, 2648; (d) Boyer, F.-D.; Hanna, I. Tetrahedron Lett. 2002, 43, 7469.
-
(2001)
Chem. Commun.
, pp. 2648
-
-
Choi, T.-L.1
Grubbs, R.H.2
-
30
-
-
0037078394
-
-
For tandem RCM reaction of dienynes see, inter alia: (a) Kim, S.-H.; Zuercher, W. J.; Bowden, N. B.; Grubbs, R. H. J. Org. Chem. 1996, 61, 1073; (b) Renaud, J.; Graf, C.-D.; Oberer, L. Angew. Chem., Int. Ed. Engl. 2000, 39, 3101; (c) Choi, T.-L.; Grubbs, R. H. Chem. Commun. 2001, 2648; (d) Boyer, F.-D.; Hanna, I. Tetrahedron Lett. 2002, 43, 7469.
-
(2002)
Tetrahedron Lett.
, vol.43
, pp. 7469
-
-
Boyer, F.-D.1
Hanna, I.2
-
32
-
-
0034681742
-
-
Wallace D.J., Cowden C.J., Kennedy D.J., Ashwood M.S., Cottrell I.F., Dolling U.-H. Tetrahedron Lett. 41:2000;2027.
-
(2000)
Tetrahedron Lett.
, vol.41
, pp. 2027
-
-
Wallace, D.J.1
Cowden, C.J.2
Kennedy, D.J.3
Ashwood, M.S.4
Cottrell, I.F.5
Dolling, U.-H.6
-
33
-
-
0035107363
-
-
Wallace D.J., Bulger P.G., Kennedy D.J., Ashwood M.S., Cottrell I.F., Dolling U.-H. Synlett. 2001;357.
-
(2001)
Synlett
, pp. 357
-
-
Wallace, D.J.1
Bulger, P.G.2
Kennedy, D.J.3
Ashwood, M.S.4
Cottrell, I.F.5
Dolling, U.-H.6
-
34
-
-
0035826378
-
-
Wallace D.J., Goodman J.M., Kennedy D.J., Davies A.J., Cowden C.J., Ashwood M.S., Cottrell I.F., Dolling U.-H., Reider P.J. Org. Lett. 3:2001;671.
-
(2001)
Org. Lett.
, vol.3
, pp. 671
-
-
Wallace, D.J.1
Goodman, J.M.2
Kennedy, D.J.3
Davies, A.J.4
Cowden, C.J.5
Ashwood, M.S.6
Cottrell, I.F.7
Dolling, U.-H.8
Reider, P.J.9
-
36
-
-
85031229554
-
-
All new compounds gave satisfactory spectroscopic and HRMS or microanalytical data
-
All new compounds gave satisfactory spectroscopic and HRMS or microanalytical data.
-
-
-
-
37
-
-
85031218164
-
-
6: C, 55.81; H, 7.02
-
4Na (M+Na) 409.2355, found 409.2375.
-
-
-
-
38
-
-
33746236970
-
-
Schwab P., France M.B., Ziller J.W., Grubbs R.H. Angew. Chem., Int. Ed. Engl. 34:1995;2039.
-
(1995)
Angew. Chem., Int. Ed. Engl.
, vol.34
, pp. 2039
-
-
Schwab, P.1
France, M.B.2
Ziller, J.W.3
Grubbs, R.H.4
-
41
-
-
85031222998
-
-
To a solution of octaene 3 (75 mg, 0.203 mmol) in dichloromethane (6.0 mL) was added catalyst 11 (18.0 mg, 0.02 mmol), the mixture was de-gassed and stirred for 3 h whereupon a further 10 mol% of catalyst was added and stirring continued for 24 h. Concentration and column chromatography (EtOAc:hexanes 1:1 increasing to EtOAc and then EtOAc:MeOH 4:1) afforded 10a (14.0 mg, 25%), 10b (19.5 mg, 35%) and 10c (14.0 mg, 24%)
-
4Na (M+Na) 297.1103, found 297.1104.
-
-
-
-
42
-
-
85031234957
-
-
f value
-
f value.
-
-
-
-
43
-
-
85031224437
-
-
Modeling studies performed using PC Sparton Pro suggest dipole moments: 10a=0.53 debye, 10b=2.46 debye and 10c=4.26 debye. More rigorous molecular modeling studies are planned and will be presented in a full paper
-
Modeling studies performed using PC Sparton Pro suggest dipole moments: 10a=0.53 debye, 10b=2.46 debye and 10c=4.26 debye. More rigorous molecular modeling studies are planned and will be presented in a full paper.
-
-
-
-
44
-
-
85031216217
-
-
The rapid formation of five membered rings in RCM reactions has been noted before, see inter alia, Refs. 3a, 3c, 5a, 8c
-
The rapid formation of five membered rings in RCM reactions has been noted before, see inter alia, Refs. 3a, 3c, 5a, 8c.
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