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Volumn 15, Issue 5, 2003, Pages 665-677

Clustering of immunoreceptor tyrosine-based activation motif-containing signalling subunits in CD4+ T cells is an optimal signal for IFN-γ production, but not for the production of IL-4

Author keywords

Cytokine; Gene therapy; Mouse; Th1; Th2; TCR

Indexed keywords

COLLAGEN ANTIBODY; COLLAGEN TYPE 2; GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 4; KEYHOLE LIMPET HEMOCYANIN; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT; RETROVIRUS VECTOR; TYROSINE;

EID: 0037406181     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxg064     Document Type: Article
Times cited : (6)

References (53)
  • 1
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25)
    • Sakaguchi, S., Sakaguchi, N., Asano, M,, Itoh, M. and Toda, M. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). J. Immunol. 155:1151.
    • (1995) J. Immunol. , vol.155 , pp. 1151
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 2
    • 0028179230 scopus 로고
    • + T cells are important for the balance between protective and pathogenic cell-mediated immunity
    • + T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. 179:589.
    • (1994) J. Exp. Med. , vol.179 , pp. 589
    • Powrie, F.1    Correa-Oliveira, R.2    Mauze, S.3    Coffman, R.L.4
  • 4
    • 0032514763 scopus 로고    scopus 로고
    • Gene therapy in allergic encephalomyelitis using myelin basic protein-specific T cells engineered to express latent transforming growth factor-β1
    • Chen, L. Z., Hochwald, G. M., Huang, C., Dakin, G., Tao, H., Cheng, C., Simmons, W. J., Dranoff, G. and Thorbecke, G. J. 1998. Gene therapy in allergic encephalomyelitis using myelin basic protein-specific T cells engineered to express latent transforming growth factor-β1. Proc. Natl Acad. Sci. USA 95:12516.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 12516
    • Chen, L.Z.1    Hochwald, G.M.2    Huang, C.3    Dakin, G.4    Tao, H.5    Cheng, C.6    Simmons, W.J.7    Dranoff, G.8    Thorbecke, G.J.9
  • 5
    • 0029150012 scopus 로고
    • h2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice
    • h2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice. J. Immunol. 155:4052.
    • (1995) J. Immunol. , vol.155 , pp. 4052
    • Gua, D.J.1    Hinton, D.R.2    Stohlman, S.A.3
  • 8
    • 0029559755 scopus 로고
    • Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor
    • Chernajovsky, Y., Adams, G., Podhajcer, O. L., Mueller, G. M., Robbins, P. D. and Feldmann, M. 1995. Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor. Gene Ther. 2:731.
    • (1995) Gene Ther. , vol.2 , pp. 731
    • Chernajovsky, Y.1    Adams, G.2    Podhajcer, O.L.3    Mueller, G.M.4    Robbins, P.D.5    Feldmann, M.6
  • 9
    • 0030813880 scopus 로고    scopus 로고
    • Pathogenic lymphoid cells engineered to express TGF β1 ameliorate disease in a collagen-induced arthritis model
    • Chernajovsky, Y., Adams, G., Triantaphyllopoulos, K., Ledda, M. F. and Podhajcer, O. L. 1997. Pathogenic lymphoid cells engineered to express TGF β1 ameliorate disease in a collagen-induced arthritis model. Gene Ther. 4:553.
    • (1997) Gene Ther. , vol.4 , pp. 553
    • Chernajovsky, Y.1    Adams, G.2    Triantaphyllopoulos, K.3    Ledda, M.F.4    Podhajcer, O.L.5
  • 10
    • 0032428468 scopus 로고    scopus 로고
    • Prevention of collagen-induced arthritis by gene delivery of soluble p75 tumour necrosis factor receptor
    • Mageed, R. A., Adams, G., Woodrow, D., Podhajcer, O. L. and Chernajovsky, Y. 1998. Prevention of collagen-induced arthritis by gene delivery of soluble p75 tumour necrosis factor receptor. Gene Ther. 5:1584.
    • (1998) Gene Ther. , vol.5 , pp. 1584
    • Mageed, R.A.1    Adams, G.2    Woodrow, D.3    Podhajcer, O.L.4    Chernajovsky, Y.5
  • 12
    • 0033892744 scopus 로고    scopus 로고
    • Soluble complement receptor 1 (CD35) delivered by retrovirally infected syngeneic cells or by naked DNA injection prevents the progression of collagen-induced arthritis
    • Dreja, H., Annenkov, A. and Chernajovsky, Y. 2000. Soluble complement receptor 1 (CD35) delivered by retrovirally infected syngeneic cells or by naked DNA injection prevents the progression of collagen-induced arthritis. Arthritis Rheum. 43:1698.
    • (2000) Arthritis Rheum. , vol.43 , pp. 1698
    • Dreja, H.1    Annenkov, A.2    Chernajovsky, Y.3
  • 15
    • 0030738659 scopus 로고    scopus 로고
    • Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells
    • Mathisen, P. M., Yu, M., Johnson, J. M., Drazba, J. A. and Tuohy, V. K. 1997. Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells. J. Exp. Med. 186:159.
    • (1997) J. Exp. Med. , vol.186 , pp. 159
    • Mathisen, P.M.1    Yu, M.2    Johnson, J.M.3    Drazba, J.A.4    Tuohy, V.K.5
  • 16
    • 0028866451 scopus 로고
    • Gene transfer through the blood-nerve barrier: NGF-engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis
    • Kramer, R., Zhang, Y., Gehrmann, J., Gold, R., Thoenen, H. and Wekerle, H. 1995. Gene transfer through the blood-nerve barrier: NGF-engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis. Nat. Med. 1:1162.
    • (1995) Nat. Med. , vol.1 , pp. 1162
    • Kramer, R.1    Zhang, Y.2    Gehrmann, J.3    Gold, R.4    Thoenen, H.5    Wekerle, H.6
  • 17
    • 0024980981 scopus 로고
    • Antigen receptor tail clue
    • Reth, M. 1989. Antigen receptor tail clue. Nature 338:383.
    • (1989) Nature , vol.338 , pp. 383
    • Reth, M.1
  • 18
    • 0032534575 scopus 로고    scopus 로고
    • Loss of original antigenic specificity in T cell hybridomas transduced with a chimeric receptor containing single-chain Fv of an anti-collagen antibody and FcεRI-signaling γ subunit
    • Annenkov, A. E., Moyes, S. P., Eshhar, Z., Mageed, R. A. and Chernajovsky, Y. 1998. Loss of original antigenic specificity in T cell hybridomas transduced with a chimeric receptor containing single-chain Fv of an anti-collagen antibody and FcεRI-signaling γ subunit. J. Immunol. 161:6604.
    • (1998) J. Immunol. , vol.161 , pp. 6604
    • Annenkov, A.E.1    Moyes, S.P.2    Eshhar, Z.3    Mageed, R.A.4    Chernajovsky, Y.5
  • 19
    • 0034114370 scopus 로고    scopus 로고
    • Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR ζ
    • Annenkov, A. and Chernajovsky, Y. 2000. Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR ζ. Gene Ther. 7:714.
    • (2000) Gene Ther. , vol.7 , pp. 714
    • Annenkov, A.1    Chernajovsky, Y.2
  • 20
    • 0036516095 scopus 로고    scopus 로고
    • Highly efficient gene transfer into antigen-specific primary mouse lymphocytes with replication-deficient retrovirus expressing the 10A1 envelope protein
    • Annenkov, A. E., Daly, G. M. and Chernajovsky, Y. 2002. Highly efficient gene transfer into antigen-specific primary mouse lymphocytes with replication-deficient retrovirus expressing the 10A1 envelope protein. J. Gene Med. 4:133.
    • (2002) J. Gene Med. , vol.4 , pp. 133
    • Annenkov, A.E.1    Daly, G.M.2    Chernajovsky, Y.3
  • 21
    • 0022656277 scopus 로고
    • Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal ant-type II collagen antibodies
    • Holmdahl, R., Rubin, K., Klareskog, L., Larsson, E. and Wigzell, H. 1986. Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal ant-type II collagen antibodies. Arthritis Rheum. 29:400.
    • (1986) Arthritis Rheum. , vol.29 , pp. 400
    • Holmdahl, R.1    Rubin, K.2    Klareskog, L.3    Larsson, E.4    Wigzell, H.5
  • 22
    • 0018652555 scopus 로고
    • Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens
    • Ledbetter, J. A. and Herzenberg, L. A. 1979. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47:63.
    • (1979) Immunol. Rev. , vol.47 , pp. 63
    • Ledbetter, J.A.1    Herzenberg, L.A.2
  • 23
    • 0015516429 scopus 로고
    • Structural studies on cartilage collagen employing limited cleavage and solubilization with pepsin
    • Miller, E. J. 1972. Structural studies on cartilage collagen employing limited cleavage and solubilization with pepsin. Biochemistry 11:4903.
    • (1972) Biochemistry , vol.11 , pp. 4903
    • Miller, E.J.1
  • 24
    • 0030604714 scopus 로고    scopus 로고
    • The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
    • Ho, I. C., Hodge, M. R., Rooney, J. W. and Glimcher, L. H. 1996. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85:973.
    • (1996) Cell , vol.85 , pp. 973
    • Ho, I.C.1    Hodge, M.R.2    Rooney, J.W.3    Glimcher, L.H.4
  • 25
    • 0034176856 scopus 로고    scopus 로고
    • Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease
    • Costa, G. L., Benson, J. M., Seroogy, C. M., Achacoso, P., Fathman, C. G. and Nolan, G. P. 2000. Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease. J. Immunol. 164:3581.
    • (2000) J. Immunol. , vol.164 , pp. 3581
    • Costa, G.L.1    Benson, J.M.2    Seroogy, C.M.3    Achacoso, P.4    Fathman, C.G.5    Nolan, G.P.6
  • 27
    • 0033558278 scopus 로고    scopus 로고
    • Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: Relationship to the quality of individual TCR signaling events
    • Itoh, Y., Hemmer, B., Martin, R. and Germain, R. N. 1999. Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: relationship to the quality of individual TCR signaling events. J. Immunol. 162:2073.
    • (1999) J. Immunol. , vol.162 , pp. 2073
    • Itoh, Y.1    Hemmer, B.2    Martin, R.3    Germain, R.N.4
  • 28
    • 0032526345 scopus 로고    scopus 로고
    • Relationships among TCR ligand potency, thresholds for effector function elicitation, and the quality of early signaling events in human T cells
    • Hemmer, B., Stefanova, I., Vergelli, M., Germain, R. N. and Martin, R. 1998. Relationships among TCR ligand potency, thresholds for effector function elicitation, and the quality of early signaling events in human T cells. J. Immunol. 160:5807.
    • (1998) J. Immunol. , vol.160 , pp. 5807
    • Hemmer, B.1    Stefanova, I.2    Vergelli, M.3    Germain, R.N.4    Martin, R.5
  • 29
    • 0029037210 scopus 로고
    • Serial triggering of many T-cell receptors by a few peptide-MHC complexes
    • Valitutti, S., Muller, S., Cella, M., Padovan, E. and Lanzavecchia, A. 1995. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 375:148.
    • (1995) Nature , vol.375 , pp. 148
    • Valitutti, S.1    Muller, S.2    Cella, M.3    Padovan, E.4    Lanzavecchia, A.5
  • 30
    • 0025998529 scopus 로고
    • T-cell and basophil activation through the cytoplasmic tail of the T-cell-receptor ζ family protein
    • Letourneur, F. and Klausner, R. D. 1991. T-cell and basophil activation through the cytoplasmic tail of the T-cell-receptor ζ family protein. Proc. Natl Acad. Sci. USA 88:8905.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 8905
    • Letourneur, F.1    Klausner, R.D.2
  • 31
    • 0026064305 scopus 로고
    • The cytoplasmic domain of the Fc receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathway
    • Irving, B. A. and Weiss, A. 1991. The cytoplasmic domain of the Fc receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathway. Cell 64:891.
    • (1991) Cell , vol.64 , pp. 891
    • Irving, B.A.1    Weiss, A.2
  • 33
    • 0027471898 scopus 로고
    • Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody binding domains and the γ or ζ subunits of the immunoglobulin and T-cell receptors
    • Eshhar, Z., Walks, T., Gross, G. and Schindler, D. G. 1993. Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody binding domains and the γ or ζ subunits of the immunoglobulin and T-cell receptors. Proc. Natl Acad. Sci. USA 90:720.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 720
    • Eshhar, Z.1    Walks, T.2    Gross, G.3    Schindler, D.G.4
  • 34
    • 0028902765 scopus 로고
    • Signals through T cell receptor-ζ chain alone are insufficient to prime resting T lymphocytes
    • Brocker, T. and Karjalainen, K. 1995. Signals through T cell receptor-ζ chain alone are insufficient to prime resting T lymphocytes. J. Exp. Med. 181:1653.
    • (1995) J. Exp. Med. , vol.181 , pp. 1653
    • Brocker, T.1    Karjalainen, K.2
  • 35
    • 0026537801 scopus 로고
    • Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor ζ chain
    • Romeo, C., Amiot, M. and Seed, B. 1992. Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor ζ chain. Cell 68:889.
    • (1992) Cell , vol.68 , pp. 889
    • Romeo, C.1    Amiot, M.2    Seed, B.3
  • 37
    • 0028182749 scopus 로고
    • Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling
    • Pages, F., Ragueneau, M., Rottapel, R., Truneh, A., Nunes, J., Imbert, J. and Olive, D. 1994. Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling. Nature 369:327.
    • (1994) Nature , vol.369 , pp. 327
    • Pages, F.1    Ragueneau, M.2    Rottapel, R.3    Truneh, A.4    Nunes, J.5    Imbert, J.6    Olive, D.7
  • 38
    • 0031567886 scopus 로고    scopus 로고
    • Analysis of CD28 cytoplasmic tail tyrosine residues as regulators and substrates for the protein tyrosine kinases, EMT and LCK
    • King, P. D., Sadra, A., Teng, J. M., Xiao-Rong, L., Han, A., Selvakumar, A., August, A. and Dupont, B. 1997. Analysis of CD28 cytoplasmic tail tyrosine residues as regulators and substrates for the protein tyrosine kinases, EMT and LCK. J. Immunol. 158:580.
    • (1997) J. Immunol. , vol.158 , pp. 580
    • King, P.D.1    Sadra, A.2    Teng, J.M.3    Xiao-Rong, L.4    Han, A.5    Selvakumar, A.6    August, A.7    Dupont, B.8
  • 40
    • 0035159272 scopus 로고    scopus 로고
    • Cutting edge: The related molecules CD28 and inducible costimulator deliver both unique and complementary signals required for optimal T cell activation
    • Gonzalo, J.-A., Delaney, T., Corcoran, J., Goodearl, A., Gutierrez-Ramos, J. C. and Coyle, A. J. 2001. Cutting edge: the related molecules CD28 and inducible costimulator deliver both unique and complementary signals required for optimal T cell activation. J. Immunol. 166:1.
    • (2001) J. Immunol. , vol.1 , pp. 166
    • Gonzalo, J.-A.1    Delaney, T.2    Corcoran, J.3    Goodearl, A.4    Gutierrez-Ramos, J.C.5    Coyle, A.J.6
  • 42
    • 0034655166 scopus 로고    scopus 로고
    • LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response
    • Tamada, K., Shimozaki, K., Chapoval, A. I., Zhai, Y., Su, J., Chen, S.-F., Hsieh, S.-L., Nagata, S., Ni, J. and Chen, L. 2000. LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response. J. Immunol. 164:4105.
    • (2000) J. Immunol. , vol.164 , pp. 4105
    • Tamada, K.1    Shimozaki, K.2    Chapoval, A.I.3    Zhai, Y.4    Su, J.5    Chen, S.-F.6    Hsieh, S.-L.7    Nagata, S.8    Ni, J.9    Chen, L.10
  • 43
    • 0035869569 scopus 로고    scopus 로고
    • B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function
    • Tamura, H., Dong, H., Zhu, G., Sica, G. L., Flies, D. B., Tamada, K. and Chen, L. 2001. B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function. Blood 97:1809.
    • (2001) Blood , vol.97 , pp. 1809
    • Tamura, H.1    Dong, H.2    Zhu, G.3    Sica, G.L.4    Flies, D.B.5    Tamada, K.6    Chen, L.7
  • 45
    • 0034667688 scopus 로고    scopus 로고
    • Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS
    • Wang, S., Zhu, G., Chapoval, A. I., Dong, H., Tamada, K., Ni, J. and Chen, L. 2000. Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS. Blood 96:2808.
    • (2000) Blood , vol.96 , pp. 2808
    • Wang, S.1    Zhu, G.2    Chapoval, A.I.3    Dong, H.4    Tamada, K.5    Ni, J.6    Chen, L.7
  • 47
    • 0034176032 scopus 로고    scopus 로고
    • Vav synergizes with protein kinase Cθ to mediate IL-4 gene expression in response to CD28 costimulation in T cells
    • Hehner, S. P., Li-Weber, M., Giaisi, M., Droge, W., Krammer, P. H. and Schmitz, M. L. 2000. Vav synergizes with protein kinase Cθ to mediate IL-4 gene expression in response to CD28 costimulation in T cells. J. Immunol. 164:3829.
    • (2000) J. Immunol. , vol.164 , pp. 3829
    • Hehner, S.P.1    Li-Weber, M.2    Giaisi, M.3    Droge, W.4    Krammer, P.H.5    Schmitz, M.L.6
  • 50
    • 0031205443 scopus 로고    scopus 로고
    • Selective loss of the calcium ion signaling pathway in T cells maturing toward a T helper 2 phenotype
    • Sloan-Lancaster, J., Steinberg, T. and Allen, P. 1997. Selective loss of the calcium ion signaling pathway in T cells maturing toward a T helper 2 phenotype. J. Immunol. 159:1160.
    • (1997) J. Immunol. , vol.159 , pp. 1160
    • Sloan-Lancaster, J.1    Steinberg, T.2    Allen, P.3
  • 51
    • 0028342952 scopus 로고
    • Signal transmission between the plasma membrane and nucleus of T lymphocytes
    • Crabtree, G. R. and Clipstone, N. A. 1994. Signal transmission between the plasma membrane and nucleus of T lymphocytes. Annu. Rev. Biochem. 63:1045.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 1045
    • Crabtree, G.R.1    Clipstone, N.A.2
  • 52
    • 0026559309 scopus 로고
    • Failure to synthesize the CD3-γ chain. Consequences for T cell antigen receptor assembly, processing, and expression
    • Geisler, C. 1992. Failure to synthesize the CD3-γ chain. Consequences for T cell antigen receptor assembly, processing, and expression. J. Immunol. 148:2437.
    • (1992) J. Immunol. , vol.148 , pp. 2437
    • Geisler, C.1
  • 53
    • 0035889157 scopus 로고    scopus 로고
    • Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes
    • Geiger, T. L., Nguyen, P., Leitenberg, D. and Flavell, R. A. 2001. Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes. Blood 98:2364.
    • (2001) Blood , vol.98 , pp. 2364
    • Geiger, T.L.1    Nguyen, P.2    Leitenberg, D.3    Flavell, R.A.4


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