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Volumn 8, Issue 5, 1996, Pages 689-699

Biological characteristics of an immunoregulatory activity secreted by an autoreactive CD4+ T cell clone that suppresses autoimmune diabetes in non-obese diabetic mice

Author keywords

Allogeneic mixed lymphocyte reaction; Cytokine; Insulin dependent diabetes mellitus; Non obese diabetic mice; Regulatory T lymphocyte; Syngeneic mixed lymphocyte reaction

Indexed keywords

CD4 ANTIGEN; CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4;

EID: 0029871013     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.5.689     Document Type: Article
Times cited : (8)

References (49)
  • 1
    • 0025234628 scopus 로고
    • Type I diabetes: A chronic autoimmune disease of human, mouse, and rat
    • Castano, L and Eisenbarth, G S 1990 Type I diabetes: a chronic autoimmune disease of human, mouse, and rat Annu Rev Immunol. 8:647.
    • (1990) Annu Rev Immunol. , vol.8 , pp. 647
    • Castano, L.1    Eisenbarth, G.S.2
  • 3
    • 0002758516 scopus 로고
    • The NOD mouse a model for analyzing the interplay between heredity and environment in development of autoimmune disease
    • Leiter, E H 1993 The NOD mouse a model for analyzing the interplay between heredity and environment in development of autoimmune disease. ILAR News 35 4.
    • (1993) ILAR News , vol.35 , pp. 4
    • Leiter, E.H.1
  • 4
    • 0025301142 scopus 로고
    • MHC-linked protection from diabetes dissociated from clonal deletion of T cells
    • Bohme, J., Schuhbaur, B , Kanagawa, O., Benoist, C and Mathis, D 1990 MHC-linked protection from diabetes dissociated from clonal deletion of T cells Science 249 293.
    • (1990) Science , vol.249 , pp. 293
    • Bohme, J.1    Schuhbaur, B.2    Kanagawa, O.3    Benoist, C.4    Mathis, D.5
  • 5
    • 0027429150 scopus 로고
    • Failure of a protective major histocompatibility complex class II molecule to delete autoreactive T cells in autoimmune diabetes
    • Slattery, R. M , Miller, J F. A. P., Heath, W R and Charlton, B. 1993 Failure of a protective major histocompatibility complex class II molecule to delete autoreactive T cells in autoimmune diabetes Proc Natl Acad Sci USA 90 10808
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10808
    • Slattery, R.M.1    Miller, J.F.A.P.2    Heath, W.R.3    Charlton, B.4
  • 6
    • 0027378612 scopus 로고
    • Following a diabetogenic T cell from genesis to pathogenesis
    • Katz, J D , Wang, B , Haskins, K , Benoist C and Mathis, D 1993 Following a diabetogenic T cell from genesis to pathogenesis Cell 74:1089
    • (1993) Cell , vol.74 , pp. 1089
    • Katz, J.D.1    Wang, B.2    Haskins, K.3    Benoist, C.4    Mathis, D.5
  • 8
    • 0023879559 scopus 로고
    • Defective activation of T suppresor cell function in nonobese diabetic mice
    • Serreze, D V and Leiter, E H. 1988 Defective activation of T suppresor cell function in nonobese diabetic mice J Immunol. 140:3801
    • (1988) J Immunol. , vol.140 , pp. 3801
    • Serreze, D.V.1    Leiter, E.H.2
  • 9
    • 0027173029 scopus 로고
    • Defects in the differentiation and function of antigen presenting cells in NOD/ Lt mice
    • Serezze, D V Gaskins, H R and Leiter, E. H 1993 Defects in the differentiation and function of antigen presenting cells in NOD/ Lt mice J Immunol 150:2534
    • (1993) J Immunol , vol.150 , pp. 2534
    • Serezze, D.V.1    Gaskins, H.R.2    Leiter, E.H.3
  • 10
    • 0027443570 scopus 로고
    • Haematopoetic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: Defective regulation of cytokine receptors and protein kinase C
    • Serreze D V., Gaedeke, J and Leiter, E 1993 Haematopoetic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C Proc. Natl Acad Sci. USA 90 9625
    • (1993) Proc. Natl Acad Sci. USA , vol.90 , pp. 9625
    • Serreze, D.V.1    Gaedeke, J.2    Leiter, E.3
  • 12
    • 0025735437 scopus 로고
    • Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice
    • Zipris, D., Lazarus, A. H., Crow, A R , Hadzija M and Delovitch, T L 1991 Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice J Immunol 146 3763
    • (1991) J Immunol , vol.146 , pp. 3763
    • Zipris, D.1    Lazarus, A.H.2    Crow, A.R.3    Hadzija, M.4    Delovitch, T.L.5
  • 15
    • 0026340085 scopus 로고
    • On the binding of tumor necrosis factor (TNF) to heparin and the release in-vivo of the TNF-binding protein I by heparin
    • Lantz M. Thysell, H. Nisson, E and Olson, I. 1991. On the binding of tumor necrosis factor (TNF) to heparin and the release in-vivo of the TNF-binding protein I by heparin. J. Clin Invest 88 2026
    • (1991) J. Clin Invest , vol.88 , pp. 2026
    • Lantz, M.1    Thysell, H.2    Nisson, E.3    Olson, I.4
  • 16
    • 0025736891 scopus 로고
    • Interferon gamma c-terminal function, new working hypothesis Heparin sulfate and heparin new targets for IFN-gamma, protect, relax the cytokine and regulate the activity
    • Lortat-Jacob, H. and Grimaud, J-A 1991 Interferon gamma c-terminal function, new working hypothesis Heparin sulfate and heparin new targets for IFN-gamma, protect, relax the cytokine and regulate the activity Cell. Mol Biol 37:253
    • (1991) Cell. Mol Biol , vol.37 , pp. 253
    • Lortat-Jacob, H.1    Grimaud, J.-A.2
  • 17
    • 0026776936 scopus 로고
    • Transforming growth factor β-1 is a heparin-binding protein, identification of putative heparin-binding regions and isolation of heparins with varying affinity for TGFβ-1
    • McCaffrey, T A , Falcone, D. J and Du, B. 1992 Transforming growth factor β-1 is a heparin-binding protein, identification of putative heparin-binding regions and isolation of heparins with varying affinity for TGFβ-1. J. Cell Physiol. 152:430.
    • (1992) J. Cell Physiol. , vol.152 , pp. 430
    • McCaffrey, T.A.1    Falcone, D.J.2    Du, B.3
  • 18
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin J M , Przybyla A. E., MacDonald, R J and Rutter, W. J 1979 Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18 5294
    • (1979) Biochemistry , vol.18 , pp. 5294
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 19
    • 0028261194 scopus 로고
    • Effective amplification of long targets from cloned inserts and human genomic DNA
    • Cheng, S , Fockler, C , Barnes, W M. and Higuchi, R 1994 Effective amplification of long targets from cloned inserts and human genomic DNA. Proc Natl Acad. Sci USA 91 5695
    • (1994) Proc Natl Acad. Sci USA , vol.91 , pp. 5695
    • Cheng, S.1    Fockler, C.2    Barnes, W.M.3    Higuchi, R.4
  • 20
    • 0025792001 scopus 로고
    • The JAM test: A simple assay for DNA fragmentation and cell death
    • Matzinger, P. 1991. The JAM test: a simple assay for DNA fragmentation and cell death J Immunol Methods 145 185
    • (1991) J Immunol Methods , vol.145 , pp. 185
    • Matzinger, P.1
  • 21
    • 0024353079 scopus 로고
    • TH1 and TH2 cells different patterns of lymphokine secretion lead to different functional properties
    • Mosmann, T. R and Coffman, R L 1989 TH1 and TH2 cells different patterns of lymphokine secretion lead to different functional properties. Ann Rev Immunol 7 145
    • (1989) Ann Rev Immunol , vol.7 , pp. 145
    • Mosmann, T.R.1    Coffman, R.L.2
  • 23
    • 0027092667 scopus 로고
    • T-cell subsets and autoimmunity
    • Mason, D and Fowell, D 1992 T-cell subsets and autoimmunity Curr Opin Immunol 4 728
    • (1992) Curr Opin Immunol , vol.4 , pp. 728
    • Mason, D.1    Fowell, D.2
  • 25
    • 0029030964 scopus 로고
    • T helper cell subsets in insulin-dependent diabetes
    • Katz, J D , Benoist, C and Mathis, D 1995 T helper cell subsets in insulin-dependent diabetes. Science 268 1185.
    • (1995) Science , vol.268 , pp. 1185
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 26
    • 0028982517 scopus 로고
    • h2 subsets, paradigms lost?
    • h2 subsets, paradigms lost? Immunol Today 16 374
    • (1995) Immunol Today , vol.16 , pp. 374
    • Kelso, A.1
  • 27
    • 0027163933 scopus 로고
    • Interleukin 4 suppresses interleukin 2 and interferon γ production by naive T cells stimulated by accessory cell-dependent receptor engagement
    • B
    • Tanaka, T , Hu-Li J , Seder R A , Fazekas, D S G., B and Paul, W E 1993 Interleukin 4 suppresses interleukin 2 and interferon γ production by naive T cells stimulated by accessory cell-dependent receptor engagement. Proc Natl Acad. Sci USA 90 5914
    • (1993) Proc Natl Acad. Sci USA , vol.90 , pp. 5914
    • Tanaka, T.1    Hu-Li, J.2    Seder, R.A.3    Fazekas, D.S.G.4    Paul, W.E.5
  • 29
    • 0008066869 scopus 로고
    • IL-4 and IFN-γ direct the development of distinct subsets of helper T cells
    • Swain, S L , Weinberg, A. D , English, M and Huston, G 1990 IL-4 and IFN-γ direct the development of distinct subsets of helper T cells Fedn Proc 4:2020
    • (1990) Fedn Proc , vol.4 , pp. 2020
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 30
    • 0026056142 scopus 로고
    • h2 responses in a murine model of cutaneous leishmaniasis
    • h2 responses in a murine model of cutaneous leishmaniasis J Immunol 147 3149
    • (1991) J Immunol , vol.147 , pp. 3149
    • Scott, P.1
  • 31
    • 0029031023 scopus 로고
    • Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response
    • Lucas, P J , Negishi, I., Nakayama, K-I , Fields, L. E and Loh, D Y 1995 Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response J. Immunol 154:5757
    • (1995) J. Immunol , vol.154 , pp. 5757
    • Lucas, P.J.1    Negishi, I.2    Nakayama, K.-I.3    Fields, L.E.4    Loh, D.Y.5
  • 32
    • 0029073050 scopus 로고
    • B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4
    • Freeman, G J., Boussiotis, V A , Anumanthan, A , Bernstein, G M , Ke, X -Y , Rennert, P D , Gray, G S , Gribben J G and Nadler, L M 1995 B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4 Immunity 2:523
    • (1995) Immunity , vol.2 , pp. 523
    • Freeman, G.J.1    Boussiotis, V.A.2    Anumanthan, A.3    Bernstein, G.M.4    Ke, X.Y.5    Rennert, P.D.6    Gray, G.S.7    Gribben, J.G.8    Nadler, L.M.9
  • 35
    • 0028237348 scopus 로고
    • CD28-B7 interactions in T-cell activation
    • Allison, J P 1994 CD28-B7 interactions in T-cell activation. Curr Opin. Immunol 6:414
    • (1994) Curr Opin. Immunol , vol.6 , pp. 414
    • Allison, J.P.1
  • 36
    • 0029073090 scopus 로고
    • Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation?
    • Thompson, C B. 1995 Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? Cell 81 979
    • (1995) Cell , vol.81 , pp. 979
    • Thompson, C.B.1
  • 37
    • 0018777076 scopus 로고
    • Activation of suppressor T cells in human T cells responsive to autologous non-T cells
    • Smith, J B and Knowlton, R. P 1979 Activation of suppressor T cells in human T cells responsive to autologous non-T cells. J Immunol 123 419.
    • (1979) J Immunol , vol.123 , pp. 419
    • Smith, J.B.1    Knowlton, R.P.2
  • 38
    • 0018764839 scopus 로고
    • Specificty and suppressor function of human T cells responsive to autologous non-T cells
    • Sakane, T. and Green, I 1979. Specificty and suppressor function of human T cells responsive to autologous non-T cells J. Immunol 123:419
    • (1979) J. Immunol , vol.123 , pp. 419
    • Sakane, T.1    Green, I.2
  • 39
    • 0024434159 scopus 로고
    • Comparison of high-and-low diabetes incidence NOD mouse strains
    • Baxter, A G., Adams, M A and Mandel, T E 1989 Comparison of high-and-low diabetes incidence NOD mouse strains Diabetes 38:1296.
    • (1989) Diabetes , vol.38 , pp. 1296
    • Baxter, A.G.1    Adams, M.A.2    Mandel, T.E.3
  • 40
    • 0019448022 scopus 로고
    • Defective suppressor cell generation in juvenile diabetes
    • Lederman, M M , Ellner, J J. and Rodman, H M. 1981 Defective suppressor cell generation in juvenile diabetes. J. Immunol. 127:2051
    • (1981) J. Immunol. , vol.127 , pp. 2051
    • Lederman, M.M.1    Ellner, J.J.2    Rodman, H.M.3
  • 41
    • 0021713204 scopus 로고
    • Autologous mixed lymphocyte reaction in man XV Cellular and molecular basis of deficient autologous mixed lymphocyte response in insulin-dependent diabetes mellitus
    • Chandy, K G., Charles, A M , Kershnar, A , Buckingham, E., Waldeck, N and Gupta, S 1984 Autologous mixed lymphocyte reaction in man XV Cellular and molecular basis of deficient autologous mixed lymphocyte response in insulin-dependent diabetes mellitus J. Clin Immunol 4:424
    • (1984) J. Clin Immunol , vol.4 , pp. 424
    • Chandy, K.G.1    Charles, A.M.2    Kershnar, A.3    Buckingham, E.4    Waldeck, N.5    Gupta, S.6
  • 43
    • 0026321504 scopus 로고
    • Linkage of faulty major histocompatibility complex class I to autoimmune diabetes
    • Faustman, D., Li, X., Lin, H , Fu, Y , Eisenbarth, G , Avrch, J and Guo, J 1991 Linkage of faulty major histocompatibility complex class I to autoimmune diabetes Science 254 1756.
    • (1991) Science , vol.254 , pp. 1756
    • Faustman, D.1    Li, X.2    Lin, H.3    Fu, Y.4    Eisenbarth, G.5    Avrch, J.6    Guo, J.7
  • 44
    • 0018949404 scopus 로고
    • The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease
    • Glimcher, L H., Steinberg, A D , House, S. B. and Green, I 1980 The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease J Immunol 125:1832.
    • (1980) J Immunol , vol.125 , pp. 1832
    • Glimcher, L.H.1    Steinberg, A.D.2    House, S.B.3    Green, I.4
  • 45
    • 0020035283 scopus 로고
    • Decreased syngeneic mixed lymphocyte reaction in autoimmune susceptible mice
    • Horn, J T and Talal, N 1982 Decreased syngeneic mixed lymphocyte reaction in autoimmune susceptible mice. Scand J. Immunol 15 195
    • (1982) Scand J. Immunol , vol.15 , pp. 195
    • Horn, J.T.1    Talal, N.2
  • 46
    • 0018174178 scopus 로고
    • Failure of autologous mixed lymphocyte reaction between T and non-T cells in patients with systemic lupus erythematosis
    • Sakane, T , Steinberg, A D. and Green, I. 1978 Failure of autologous mixed lymphocyte reaction between T and non-T cells in patients with systemic lupus erythematosis. Proc. Natl Acad Sci USA 75:3464.
    • (1978) Proc. Natl Acad Sci USA , vol.75 , pp. 3464
    • Sakane, T.1    Steinberg, A.D.2    Green, I.3
  • 47
    • 0021884894 scopus 로고
    • Abnormalities in autologous mixed lymphocyte reaction-activated immunologic processes in systemic lupus erythematosis and the possible correction by IL-2
    • Takada, S., Ueda, S., Suzuki, N., Murakawa, Y., Hoshino, T., Green, I , Steinberg, A D , Horowitz, D. A and Sakane, T 1985. Abnormalities in autologous mixed lymphocyte reaction-activated immunologic processes in systemic lupus erythematosis and the possible correction by IL-2 Eur J Immunol. 15 262
    • (1985) Eur J Immunol. , vol.15 , pp. 262
    • Takada, S.1    Ueda, S.2    Suzuki, N.3    Murakawa, Y.4    Hoshino, T.5    Green, I.6    Steinberg, A.D.7    Horowitz, D.A.8    Sakane, T.9
  • 49
    • 0019739342 scopus 로고
    • The autologous mixed lymphocyte reaction
    • Weksler, M. E., Moody, C E and Kozak, R W. 1981 The autologous mixed lymphocyte reaction. Adv Immunol 31 271
    • (1981) Adv Immunol , vol.31 , pp. 271
    • Weksler, M.E.1    Moody, C.E.2    Kozak, R.W.3


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