Prevention of adoptively transferred diabetes in nonobese diabetic mice with IL-10-transduced islet-specific Th1 lymphocytes: A gene therapy model for autoimmune diabetes

Journal of Clinical Investigation

Volumn 98, Issue 8, 1996, Pages 1851-1859

  Moritani, Maki ^a   Yoshimoto, Katsuhiko ^a   Ii, Setsuko ^a   Kondo, Maki ^a   Iwahana, Hiroyuki ^a   Yamaoka, Takashi ^a   Sano, Toshiaki ^a   Nakano, Naoko ^b   Kikutani, Hitoshi ^b   Itakura, Mitsuo ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

insulin dependent diabetes mellitus; insulitis; pancreatic islet B cells (islet B cells); somatic gene therapy; Th2

Indexed keywords

CD4 ANTIGEN; COMPLEMENTARY DNA; CYCLOPHOSPHAMIDE; INTERLEUKIN 10; MESSENGER RNA; VIRUS VECTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CELL CLONE; CONTROLLED STUDY; GENE THERAPY; HELPER CELL; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 10244224047     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118986     Document Type: Article

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