-
1
-
-
0035476877
-
Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse
-
Borgland SL, Connor M, and Christie MJ (2001) Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse. J Physiol (Lond) 536:35-47.
-
(2001)
J Physiol (Lond)
, vol.536
, pp. 35-47
-
-
Borgland, S.L.1
Connor, M.2
Christie, M.J.3
-
2
-
-
0034101842
-
2, a new selective nociceptin receptor antagonist
-
2, a new selective nociceptin receptor antagonist. Br J Pharmacol 129:1183-1193.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 1183-1193
-
-
Calo, G.1
Guerrini, R.2
Bigoni, R.3
Rizzi, A.4
Marzola, G.5
Okawa, H.6
Bianchi, C.7
Lambert, D.G.8
Salvadori, S.9
Regoli, D.10
-
3
-
-
0036015187
-
[Nphe(1), Arg(14), Lys(15)]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor
-
Calo G, Rizzi A, Rizzi D, Bigoni R, Guerrini R, Marzola G, Marzola G, Marti M, McDonald J, Morari M, et al. (2002) [Nphe(1), Arg(14), Lys(15)lnociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor. Br J Pharmacol 136:303-311.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 303-311
-
-
Calo, G.1
Rizzi, A.2
Rizzi, D.3
Bigoni, R.4
Guerrini, R.5
Marzola, G.6
Marzola, G.7
Marti, M.8
McDonald, J.9
Morari, M.10
-
4
-
-
0037022377
-
Anatomical and physiological evidence for involvement of tuberoinfundibular peptide of 39 residues in nociception
-
Doboly A, Ueda H, Uchida H, Palkovits M, and Usdin TB (2002) Anatomical and physiological evidence for involvement of tuberoinfundibular peptide of 39 residues in nociception. Proc Natl Acad Sci USA 99:1651-1656.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1651-1656
-
-
Doboly, A.1
Ueda, H.2
Uchida, H.3
Palkovits, M.4
Usdin, T.B.5
-
5
-
-
0003502036
-
-
McGraw Hill Book Company, New York
-
Fields HL (1987) Pain. McGraw Hill Book Company, New York.
-
(1987)
Pain
-
-
Fields, H.L.1
-
6
-
-
0023924046
-
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
-
Hargreaves K, Dubner R, Brown F, Flores C, and Joris J (1988) A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77-88.
-
(1988)
Pain
, vol.32
, pp. 77-88
-
-
Hargreaves, K.1
Dubner, R.2
Brown, F.3
Flores, C.4
Joris, J.5
-
7
-
-
0034214841
-
NK1 (substance P) receptor antagonists - Why are they not analgesic in humans?
-
Hill R (2000) NK1 (substance P) receptor antagonists - why are they not analgesic in humans? Trends Pharmacol Sci 21:244-246.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 244-246
-
-
Hill, R.1
-
8
-
-
0024328533
-
Changes in features of degenerating primary sensory neurons with time after capsaicin treatment
-
Hiura A and Ishizuka H (1989) Changes in features of degenerating primary sensory neurons with time after capsaicin treatment. Acta Neuropathol 78:35-46.
-
(1989)
Acta Neuropathol
, vol.78
, pp. 35-46
-
-
Hiura, A.1
Ishizuka, H.2
-
9
-
-
0018956018
-
Intrathecal morphine in mice: A new technique
-
Hylden JL and Wilcox GL (1980) Intrathecal morphine in mice: a new technique. Eur J Pharmacol 67:313-316.
-
(1980)
Eur J Pharmacol
, vol.67
, pp. 313-316
-
-
Hylden, J.L.1
Wilcox, G.L.2
-
10
-
-
0019507468
-
Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice
-
Hylden JL and Wilcox GL (1981) Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice. Brain Res 217:212-215.
-
(1981)
Brain Res
, vol.217
, pp. 212-215
-
-
Hylden, J.L.1
Wilcox, G.L.2
-
11
-
-
0024488786
-
Synthesis of 15-cis-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-9-deoxy-6, 9alphanitriloprostaglandin F1 methyl ester (OP-2507), a novel anti-cerebral ischemic agent
-
Iguchi S, Miyata Y, Miyake H, Arai Y, Okegawa T, and Kawasaki A (1989) Synthesis of 15-cis-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-9-deoxy-6, 9alphanitriloprostaglandin F1 methyl ester (OP-2507), a novel anti-cerebral ischemic agent. Adv Prostaglandin Thromboxane Leukot Res 19:670-673.
-
(1989)
Adv Prostaglandin Thromboxane Leukot Res
, vol.19
, pp. 670-673
-
-
Iguchi, S.1
Miyata, Y.2
Miyake, H.3
Arai, Y.4
Okegawa, T.5
Kawasaki, A.6
-
12
-
-
0035798217
-
Involvement of vanilloid receptor VR1 and prostanoids in the acid-induced writhing responses of mice
-
Ikeda Y, Ueno A, Naraba H, and Oh-ishi S (2001) Involvement of vanilloid receptor VR1 and prostanoids in the acid-induced writhing responses of mice. Life Sci 69:2911-2919.
-
(2001)
Life Sci
, vol.69
, pp. 2911-2919
-
-
Ikeda, Y.1
Ueno, A.2
Naraba, H.3
Oh-ishi, S.4
-
13
-
-
0032168994
-
Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice
-
Inoue M, Kobayashi M, Kozaki S, Zimmer A, and Ueda H (1998) Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice. Proc Natl Acad Sci USA 95:10949-10953.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 10949-10953
-
-
Inoue, M.1
Kobayashi, M.2
Kozaki, S.3
Zimmer, A.4
Ueda, H.5
-
14
-
-
0032842949
-
Dose-related opposite modulation by nociceptin/orphanin FQ of substance P-nociception in the nociceptors and spinal cord
-
Inoue M, Shimohira I, Yoshida A, Zimmer A, Takeshima H, Sakurada T, and Ueda H (1999) Dose-related opposite modulation by nociceptin/orphanin FQ of substance P-nociception in the nociceptors and spinal cord. J Pharmacol Exp Ther 291:308-313.
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 308-313
-
-
Inoue, M.1
Shimohira, I.2
Yoshida, A.3
Zimmer, A.4
Takeshima, H.5
Sakurada, T.6
Ueda, H.7
-
15
-
-
0024238775
-
Agonist-induced substance P receptor down-regulation in rat central nervous system
-
Inoue A, Takeda R, Fukuyasu T, Nakata Y, and Segawa T (1988) Agonist-induced substance P receptor down-regulation in rat central nervous system. Pharm Res 5:795-799.
-
(1988)
Pharm Res
, vol.5
, pp. 795-799
-
-
Inoue, A.1
Takeda, R.2
Fukuyasu, T.3
Nakata, Y.4
Segawa, T.5
-
16
-
-
0036200459
-
Algogen-specific pain processing in mouse spinal cord: Differential involvement of voltage -dependent Ca(2+) channels in synaptic transmission
-
Kato A, Ohkubo T, and Kitamura K (2002) Algogen-specific pain processing in mouse spinal cord: differential involvement of voltage -dependent Ca(2+) channels in synaptic transmission. Br J Pharmacol 135:1336-1342.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 1336-1342
-
-
Kato, A.1
Ohkubo, T.2
Kitamura, K.3
-
17
-
-
0030943255
-
NMDA-receptor regulation of substance P release from primary afferent nociceptors
-
Liu H, Mantyh PW, and Basbaum AI (1997) NMDA-receptor regulation of substance P release from primary afferent nociceptors. Nature (Lond) 386:721-724.
-
(1997)
Nature (Lond)
, vol.386
, pp. 721-724
-
-
Liu, H.1
Mantyh, P.W.2
Basbaum, A.I.3
-
18
-
-
0031912743
-
Enhancement of spatial attention in nociceptin/orphanin FQ receptor-knockout mice
-
Mamiya T, Noda Y, Nishi M, Takeshima H, and Nabeshima T (1998) Enhancement of spatial attention in nociceptin/orphanin FQ receptor-knockout mice. Brain Res 783:236-240.
-
(1998)
Brain Res
, vol.783
, pp. 236-240
-
-
Mamiya, T.1
Noda, Y.2
Nishi, M.3
Takeshima, H.4
Nabeshima, T.5
-
19
-
-
0028999848
-
Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation
-
Mantyh PW, DeMaster E, Malhotra A, Ghilardi JR, Rogers SD, Mantyh CR, Liu H, Basbaum AI, Vigna SR, Maggio JE, et al. (1995) Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation. Science (Wash DC) 268:1629-1632.
-
(1995)
Science (Wash DC)
, vol.268
, pp. 1629-1632
-
-
Mantyh, P.W.1
DeMaster, E.2
Malhotra, A.3
Ghilardi, J.R.4
Rogers, S.D.5
Mantyh, C.R.6
Liu, H.7
Basbaum, A.I.8
Vigna, S.R.9
Maggio, J.E.10
-
20
-
-
0021906641
-
The autoradiographic localization of substance P receptors in the rat and bovine spinal cord and the rat and cat spinal trigeminal nucleus pars caudalis and the effects of neonatal capsaicin
-
Mantyh PW and Hunt SP (1985) The autoradiographic localization of substance P receptors in the rat and bovine spinal cord and the rat and cat spinal trigeminal nucleus pars caudalis and the effects of neonatal capsaicin. Brain Res 332:315-324.
-
(1985)
Brain Res
, vol.332
, pp. 315-324
-
-
Mantyh, P.W.1
Hunt, S.P.2
-
21
-
-
0032531784
-
Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to nociceptin/orphanin FQ
-
Meis S and Pape HC (1998) Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to nociceptin/orphanin FQ. J Neurosci 18:8133-8144.
-
(1998)
J Neurosci
, vol.18
, pp. 8133-8144
-
-
Meis, S.1
Pape, H.C.2
-
22
-
-
0013851199
-
Pain mechanisms: A new theory
-
Melzack R and Wall PD (1965) Pain mechanisms: a new theory. Science (Wash DC) 150:971-979.
-
(1965)
Science (Wash DC)
, vol.150
, pp. 971-979
-
-
Melzack, R.1
Wall, P.D.2
-
23
-
-
0031553387
-
Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor
-
Meunier JC (1997) Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor. Eur J Pharmacol 340:1-15.
-
(1997)
Eur J Pharmacol
, vol.340
, pp. 1-15
-
-
Meunier, J.C.1
-
24
-
-
0029166509
-
Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
-
Meunier JC, Mollereau C, Toll L, Suandeau C, Moisand C, Alvinerie P, Butour JL, Guillemot JC, Ferrara P, Monsarrat B, et al. (1995) Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature (Lond) 377:532-535.
-
(1995)
Nature (Lond)
, vol.377
, pp. 532-535
-
-
Meunier, J.C.1
Mollereau, C.2
Toll, L.3
Suandeau, C.4
Moisand, C.5
Alvinerie, P.6
Butour, J.L.7
Guillemot, J.C.8
Ferrara, P.9
Monsarrat, B.10
-
25
-
-
0034850298
-
The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family
-
Mogil JS and Pasternak GW (2001) The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family. Pharmacol Rev 53:381-415.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 381-415
-
-
Mogil, J.S.1
Pasternak, G.W.2
-
26
-
-
0030983770
-
Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor
-
Nishi M, Houtani T, Noda Y, Mamiya T, Sato K, Doi T, Kuno J, Takeshima H, Nukada T, Nabeshima T, et al. (1997) Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor. EMBO J 16:1858-1864.
-
(1997)
EMBO J
, vol.16
, pp. 1858-1864
-
-
Nishi, M.1
Houtani, T.2
Noda, Y.3
Mamiya, T.4
Sato, K.5
Doi, T.6
Kuno, J.7
Takeshima, H.8
Nukada, T.9
Nabeshima, T.10
-
27
-
-
0034683206
-
In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist
-
Ozaki S, Kawamoto H, Itoh Y, Miyaji M, Azuma T, Ichikawa D, Nambu H, Iguchi T, Iwasawa Y, and Ohta H (2000) In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist. Eur J Pharmacol 402:45-53.
-
(2000)
Eur J Pharmacol
, vol.402
, pp. 45-53
-
-
Ozaki, S.1
Kawamoto, H.2
Itoh, Y.3
Miyaji, M.4
Azuma, T.5
Ichikawa, D.6
Nambu, H.7
Iguchi, T.8
Iwasawa, Y.9
Ohta, H.10
-
28
-
-
0037008392
-
Expression of orphanin FQ/nociceptin and its receptor in rat peripheral ganglia and spinal cord
-
Pettersson LM, Sundler F, and Danielsen N (2002) Expression of orphanin FQ/nociceptin and its receptor in rat peripheral ganglia and spinal cord. Brain Res 945:266-275.
-
(2002)
Brain Res
, vol.945
, pp. 266-275
-
-
Pettersson, L.M.1
Sundler, F.2
Danielsen, N.3
-
29
-
-
0037373066
-
Novel expression ofvanilloid receptor 1 (VR1) on capsaicin-insensitive fibers accounts for the analgesic effect of capsaicin cream in neuropathic pain
-
Rashid MH, Inoue M, Kondo S, Kawashima T, Bakoshi S, and Ueda H (2003) Novel expression ofvanilloid receptor 1 (VR1) on capsaicin-insensitive fibers accounts for the analgesic effect of capsaicin cream in neuropathic pain. J Pharmacol Exp Ther 304:940-948.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 940-948
-
-
Rashid, M.H.1
Inoue, M.2
Kondo, S.3
Kawashima, T.4
Bakoshi, S.5
Ueda, H.6
-
30
-
-
0029767435
-
Orphanin FQ/nociceptin-immunoreactive nerve fibers parallel those containing endogenous opioids in rat spinal cord
-
Riedl M, Shuster S, Vulchanova L, Wang J, Loh HH, and Elde R (1996) Orphanin FQ/nociceptin-immunoreactive nerve fibers parallel those containing endogenous opioids in rat spinal cord. Neuroreport 7:13691372.
-
(1996)
Neuroreport
, vol.7
, pp. 1369-1372
-
-
Riedl, M.1
Shuster, S.2
Vulchanova, L.3
Wang, J.4
Loh, H.H.5
Elde, R.6
-
31
-
-
0030838083
-
Pharmacological characterization of orphanin FQ/nociceptin and its fragments
-
Rossi GC, Leventhal L, Bolan E, and Pasternak GW (1997) Pharmacological characterization of orphanin FQ/nociceptin and its fragments. J Pharmacol Exp Ther 282:858-865.
-
(1997)
J Pharmacol Exp Ther
, vol.282
, pp. 858-865
-
-
Rossi, G.C.1
Leventhal, L.2
Bolan, E.3
Pasternak, G.W.4
-
32
-
-
0034736150
-
4-Aminoquinolines: Novel nociceptin antagonists with analgesic activity
-
Shinkai H, Ito T, Iida T, Kitao Y, Yamada H, and Uchida I (2000) 4-Aminoquinolines: novel nociceptin antagonists with analgesic activity. J Med Chem 43:4667-4677.
-
(2000)
J Med Chem
, vol.43
, pp. 4667-4677
-
-
Shinkai, H.1
Ito, T.2
Iida, T.3
Kitao, Y.4
Yamada, H.5
Uchida, I.6
-
33
-
-
0032055877
-
Tackling pain at the source: New ideas about nociceptors
-
Snider WD and McMahon SB (1998) Tackling pain at the source: new ideas about nociceptors. Neuron 20:629-632.
-
(1998)
Neuron
, vol.20
, pp. 629-632
-
-
Snider, W.D.1
McMahon, S.B.2
-
34
-
-
13144305037
-
Intrathecal administration of p-hydroxymercuribanzoate or phosphoramidon/bestatin-combined induces antinociceptive effects through different opioid mechanisms
-
Tan-No K, Taira A, Inoue M, Ohsima K, Sakurada T, Sakurada C, Silberring, Nylander I, Demuth H-U, Terenius L, et al. (1998) Intrathecal administration of p-hydroxymercuribanzoate or phosphoramidon/bestatin-combined induces antinociceptive effects through different opioid mechanisms. Neuropeptides 32:411-415.
-
(1998)
Neuropeptides
, vol.32
, pp. 411-415
-
-
Tan-No, K.1
Taira, A.2
Inoue, M.3
Ohsima, K.4
Sakurada, T.5
Sakurada, C.6
Silberring7
Nylander, I.8
Demuth, H.-U.9
Terenius, L.10
-
35
-
-
0023784328
-
Effect of a prostacyclin analog OP-2507 on acute ischemic cerebral edema in cats
-
Terawaki T, Takakuwa T, Iguchi S, Wakitani K, Kira H, Okegawa T, Kawasaki A, and Masuda Y (1988) Effect of a prostacyclin analog OP-2507 on acute ischemic cerebral edema in cats. Eur J Pharmacol 152:63-70.
-
(1988)
Eur J Pharmacol
, vol.152
, pp. 63-70
-
-
Terawaki, T.1
Takakuwa, T.2
Iguchi, S.3
Wakitani, K.4
Kira, H.5
Okegawa, T.6
Kawasaki, A.7
Masuda, Y.8
-
36
-
-
0032897697
-
In vivo molecular signal transduction of peripheral mechanisms of pain
-
Ueda H (1999) In vivo molecular signal transduction of peripheral mechanisms of pain. Jpn J Pharmacol 79:263-268.
-
(1999)
Jpn J Pharmacol
, vol.79
, pp. 263-268
-
-
Ueda, H.1
-
37
-
-
0034667560
-
Enhanced spinal nociceptin receptor expression develops morphine tolerance and dependence
-
Ueda H, Inoue M, Takeshima H, and Iwasawa Y (2000a) Enhanced spinal nociceptin receptor expression develops morphine tolerance and dependence. J Neurosci 20:7640-7647.
-
(2000)
J Neurosci
, vol.20
, pp. 7640-7647
-
-
Ueda, H.1
Inoue, M.2
Takeshima, H.3
Iwasawa, Y.4
-
38
-
-
0033782234
-
Complete inhibition of purinoceptor agonist-induced nociception by spinorphin, but not by morphine
-
Ueda H, Matsunaga S, Inoue M, Yamamoto Y, and Hazato T (2000b) Complete inhibition of purinoceptor agonist-induced nociception by spinorphin, but not by morphine. Peptides 21:1215-1221.
-
(2000)
Peptides
, vol.21
, pp. 1215-1221
-
-
Ueda, H.1
Matsunaga, S.2
Inoue, M.3
Yamamoto, Y.4
Hazato, T.5
-
39
-
-
0035425765
-
Actions of nociceptin/orphanin FQ and other prepronociceptin products on rat rostral ventromedial medulla neurons in vitro
-
Vaughan CW, Connor M, Jennings EA, Marinelli S, Allen RG, and Christie MJ (2001) Actions of nociceptin/orphanin FQ and other prepronociceptin products on rat rostral ventromedial medulla neurons in vitro. J Physiol (Lond) 534:849-859.
-
(2001)
J Physiol (Lond)
, vol.534
, pp. 849-859
-
-
Vaughan, C.W.1
Connor, M.2
Jennings, E.A.3
Marinelli, S.4
Allen, R.G.5
Christie, M.J.6
-
40
-
-
0034387776
-
Is there a gap between preclinical and clinical studies of analgesia?
-
Villanueva L (2000) Is there a gap between preclinical and clinical studies of analgesia? Trends Pharmacol Sci 21:461-462.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 461-462
-
-
Villanueva, L.1
-
41
-
-
0033609173
-
Activation of Gi1 by lysophosphatidic acid receptor without ligand in the baculovirus expression system
-
Yoshida A and Ueda H (1999) Activation of Gi1 by lysophosphatidic acid receptor without ligand in the baculovirus expression system. Biochem Biophys Res Commun 259:78-84.
-
(1999)
Biochem Biophys Res Commun
, vol.259
, pp. 78-84
-
-
Yoshida, A.1
Ueda, H.2
-
42
-
-
0034235145
-
Selective suppression of inhibitory synaptic transmission by nocistatin in the rat spinal cord dorsal horn
-
Zeilhofer HU, Selbach UM, Guhring H, Erb K, and Ahmadi S (2000) Selective suppression of inhibitory synaptic transmission by nocistatin in the rat spinal cord dorsal horn. J Neurosci 20:4922-4929.
-
(2000)
J Neurosci
, vol.20
, pp. 4922-4929
-
-
Zeilhofer, H.U.1
Selbach, U.M.2
Guhring, H.3
Erb, K.4
Ahmadi, S.5
-
43
-
-
0030777654
-
Orphanin FQ potentiates formalin-induced pain behavior and antagonizes morphine analgesia in rats
-
Zhu CB, Cao XD, Xu SF, and Wu GC (1997) Orphanin FQ potentiates formalin-induced pain behavior and antagonizes morphine analgesia in rats. Neurosci Lett 235:37-40.
-
(1997)
Neurosci Lett
, vol.235
, pp. 37-40
-
-
Zhu, C.B.1
Cao, X.D.2
Xu, S.F.3
Wu, G.C.4
-
44
-
-
0032478311
-
Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene
-
Zimmer A, Zimmer AM, Baffi J, Usdin T, Reynolds K, Konig M, Palkovits M, and Mezey E (1998) Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene. Proc Natl Acad Sci USA 95:2630-2635.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2630-2635
-
-
Zimmer, A.1
Zimmer, A.M.2
Baffi, J.3
Usdin, T.4
Reynolds, K.5
Konig, M.6
Palkovits, M.7
Mezey, E.8
-
45
-
-
0020525719
-
Ethical guidelines for investigations of experimental pain in conscious animals
-
Zimmermann M (1983) Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16:109-110.
-
(1983)
Pain
, vol.16
, pp. 109-110
-
-
Zimmermann, M.1
|