Pharmacological characterization of orphanin FQ/nociceptin and its fragments

Journal of Pharmacology and Experimental Therapeutics

Volumn 282, Issue 2, 1997, Pages 858-865

  Rossi, Grace C ^a   Leventhal, Liza ^a   Bolan, Elizabeth ^a   Pasternak, Gavril W ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DIPRENORPHINE; HALOPERIDOL; NALOXONE; NALTREXONE; NEUROPEPTIDE; NOCICEPTIN; OPIATE RECEPTOR;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; EXON; GENE MAPPING; HYPERALGESIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; STRAIN DIFFERENCE; TAIL FLICK TEST;

AMINO ACID SEQUENCE; ANALGESICS; ANIMALS; HYPERALGESIA; MALE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES, ANTISENSE; OPIOID PEPTIDES; PEPTIDE FRAGMENTS; RECEPTORS, OPIOID; SPECIES SPECIFICITY;

EID: 0030838083     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. BARE, L. A., MANSSON, E. AND YANG, D.: Expression of two variants of the human μ opioid receptor mRNA in SK-N-SH cells and human brain. FEBS Lett. 354: 213-216, 1994.
2. 3 opioid receptors with a selective monoclonal antibody. Synapse 22: 247-252, 1996.
3. BUNZOW, J. R., SAEZ, C., MORTRUD, M., BOUVIER, C., WILLIAMS, J. T., LOW, M. AND GRANDY, D. K.: Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or kappa opioid receptor type. FEBS Lett. 347: 284-288, 1994.
4. CHEN, Y., MESTEK, A., LIU, J., HURLEY, J. A. AND YU, L.: Molecular cloning and functional expression of a μ-opioid receptor from rat brain. Mol. Pharmacol. 44: 8-12, 1993.
5. CHEN, Y., FAN, Y., LIU, J., MESTEK, A., TIAN, M., KOZAK, C. A. AND YU, L.: Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family. FEBS Lett. 347: 279-283, 1994.
6. 1 system. Eur. J. Pharmacol. 250: R7-R8, 1993.
7. CHIEN, C.-C. AND PASTERNAK, G. W.: Selective antagonism of opioid analgesia by a sigma system. J. Pharmacol. Exp. Ther. 271: 1583-1590, 1994.
8. CHIEN, C.-C. AND PASTERNAK, G. W.: Sigma antagonists potentiate opioid analgesia in rats. Neurosci. Lett. 190: 137-139, 1995a.
9. CHIEN, C.-C. AND PASTERNAK, G. W.: (-)-Pentazocine analgesia in mice: Interactions with a σ receptor system. Eur. J. Pharmacol. 294: 303-308, 1995b.
10. D'AMOUR, F. E. AND SMITH, D. L.: A method for determining loss of pain sensation. J. Pharmacol. Exp. Ther. 72: 174-179, 1941.
11. DOOLEY, C. T. AND HOUGHTEN, R. A.: and Orphanin FQ: Receptor binding and analog structure activity relationships in rat brain. Life Sci. 59: PL23-PL29, 1996.
12. EVANS, C. J., KEITH, D. F., MORRISON, H., MAGENDZO, K. AND EDWARDS, R. H.: Cloning of the delta opioid receptor by functional expression. Science 258: 1952-1955, 1992.
13. FUKUDA, K., KATO, S., MORI, K., NISHI, M., TAKESHIMA, H., IWABE, N., MIYATA, T., HOUTANI, T. AND SIGUIMOTI, T.: cDNA cloning and regional distribution of a novel member of the opioid receptor family. FEBS Lett. 343: 42-46, 1994.
14. HALEY, T. J. AND MCCORMICK, W. G.: Pharmacological effects produced by intracerebral injections of drugs in the conscious mouse. Br. J. Pharmacol. 12: 12-15, 1957.
15. HOUTANI, T., NISHI, M., TAKESHIMA, H., NUKADA, T. AND SUGIMOTO, T.: Structure and regional distribution of nociceptin/orphanin FQ precursor. Biochem. Biophys. Res. Commun. 219: 714-719, 1996.
16. KEITH, D., JR., MAUNG, T., ANTON, B. AND EVANS, C.: Isolation of cDNA clones homologous to opioid receptors. Regul. Pept. 54: 143-144, 1994.
17. KIEFFER, B. L., BEFORT, K., GAVERIAUX-RUFF, C. AND HIRTH, C. G.: The δ-opioid receptor: Isolation of a cDNA by expression cloning and pharmacological characterization. Proc. Natl. Acad. Sci. U.S.A. 89: 12048-12052, 1992.
18. KING, M. A., ROSSI, G. C., CHANG, A. H., WILLIAMS, L. AND PASTERNAK, G. W.: Spinal analgesic activity of orphanin FQ/nociceptin and its fragments. Neurosci. Lett. 223: 113-116, 1997.
19. LACHOWICZ, J. E., SHEN, Y., MONSMA, F. J., JR. AND SIBLEY, D. R.: Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family. J. Neurochem. 64: 34-40, 1995.
20. 14]Orphanin FQ/nociceptin binding in mouse brain: Evidence for heterogeneity. Biochem. Biophys. Res. Commun. 230: 462-465, 1997.
21. 1 receptor. Nature 377: 532-535, 1995.
22. MIN, B. H., AUGUSTIN, L. B., FELSHEIM, R. F., FUCHS, J. A. AND LOH, H. H.: Genomic structure and analysis of promoter sequence of a mouse μ opioid receptor gene. Proc. Natl. Acad. Sci. U.S.A. 91: 9081-9085, 1994.
23. MINAMI, M., TOYA, T., KATAO, Y., MAEKAWA, K., NAKAMURA, S., ONOGI, T., KANEKO, S. AND SATOH, M.: Cloning and expression of a cDNA for the rat kappa-opioid receptor. FEBS Lett. 329: 291-295, 1993.
24. MOGIL, J. S., GRISEL, J. E., REINSCHEID, K. K., CIVELLI, O., BELKNAP, J. K. AND GRANDY, D. K.: Orphanin FQ is a functional anti-opioid peptide. Neuroscience 75: 333-337, 1996a.
25. MOGIL, J. S., GRISEL, J. E., ZHANGS, G., BELKNAP, J. K. AND GRANDY, D. K.: Functional antagonism of μ-, δ-and kappa-opioid antinociception by orphanin FQ. Neurosci. Lett. 214: 131-134, 1996b.
26. MOLLEREAU, C., PARMENTIER, M., MAILLEUX, P., BUTOUR, J. L., MOISAND, C., CHALON, P., CAPUT, D., VASSART, G. AND MEUNIER, J. C.: ORL-1, a novel member of the opioid family: cloning, functional expression and localization. FEBS Lett. 341: 33-38, 1994.
27. 3-related opioid receptor using antisense oligodeoxynucleotides. Regul. Pept. 54: 217-218, 1994.
28. 3-related opioid receptor. Mol. Pharmacol. 47: 1180-1188, 1995.
29. PAN, Y.-X., XU., J. AND PASTERNAK, G. W.: Cloning and expression of a cDNA encoding a mouse brain orphanin FQ/nociceptin precursor. Biochem. J. 315: 11-13, 1996a.
30. 3-related opioid receptor. Gene 171: 255-260, 1996b.
31. PAN, Y.-X., XU, J, RYAN-MORO, J., MATHIS, J., HOM, J. S. H., MEI, J. F. AND PASTERNAK, G. W.: Dissociation of affinity and efficacy in KOR-3 chimeras. FEBS Lett. 395: 207-210, 1996c.
32. 1 systems. Regul. Pept. 54: 219-220, 1994.
33. PASTERNAK, G. W. AND STANDIFER, K. M.: Mapping of opioid receptors using antisense oligodeoxynucleotides: Correlating their molecular biology and pharmacology. Trends Pharmacol. Sci. 16: 344-350, 1995.
34. PICK, C. G., CHENG, J., PAUL, D. AND PASTERNAK, G. W.: Genetic influences in opioid analgesic sensitivity in mice. Brain Res. 556: 295-298, 1991
35. REINSCHEID, R. K., NOTHACKER, H. P., BOURSON, A., ARDATI, A., HENNINGSEN, R. A., BUNZOW, J. R., GRANDY, D. K., LANGEN, H., MONSMA, F. J. AND CIVELLI, O.: Orphanin FQ: A neuropeptide that activates an opioidlike G protein-coupled receptor. Science 270: 792-794, 1995.
36. REISINE, T. AND BELL, G. I.: Molecular biology of opioid receptors. Trends Neurosci. 16: 506-510, 1993.
37. ROSSI, G. C., PAN, Y.-X., BROWN, G. P. AND PASTERNAK, G. W.: Antisense mapping the MOR-1 opioid receptor: Evidence for alternative splicing and a novel morphine-6β-glucuronide receptor. FEBS Lett. 369: 192-196, 1995.
38. ROSSI, G. C., LEVENTHAL, L. AND PASTERNAK, G. W.: Naloxone-sensitive orphanin FQ-induced analgesia in mice. Eur. J. Pharmacol. 311: R7-R8, 1996.
39. SPIAGGIA, A., BODNAR, R. J., KELLY, D. D. AND GLUSMAN, M.: Opiate and nonopiate mechanisms of stress-induced analgesia: Cross-tolerance between stressors. Pharmacol. Biochem. Behav. 10: 761-765, 1979.
40. STANDIFER, K. M., CHIEN, C.-C., WAHLESTEDT, C., BROWN, G. P. AND PASTERNAK, G. W.: Selective loss of δ opioid analgesia and binding by antisense oligodeoxynucleotides to a δ opioid receptor. Neuron 12: 805-810, 1994.
41. THOMPSON, R. C., MANSOUR, A., AKIL, H. AND WATSON, S. J.: Cloning and pharmacological characterization of a rat μ-opioid receptor. Neuron 11: 903-913, 1993.
42. UHL, G. R., CHILDERS, S. AND PASTERNAK, G. W.: An opiate-receptor gene family reunion. Trends Neurosci. 17: 89-93, 1994.
43. UMANS, J. G. AND INTURRISI, C. E.: Pharmacodynamics of subcutaneously administered diacetylmorphine, 6-acetylmorphine and morphine in mice. J. Pharmacol. Exp. Ther. 218: 409-415, 1981.
44. WANG, J. B., JOHNSON, P. S., IMAI, Y., PERSICO, A. M., OZENBERGER, B. A., EPPLER, C. M. AND UHL, G. R.: cDna cloning of an orphan opiate receptor gene family member and its splice variant. Febs Lett. 348: 75-79, 1994a.
45. WANG, J. B., JOHNSON, P. S., PERSICO, A. M., HAWKINS, A. L., GRIFFIN, C. A. AND UHL, G. R.: Human μ-opiate receptor: cDNA and genomic clones, pharmacologic characterization and chromosomal assignment. FEBS Lett. 338: 217-222, 1994b.
46. WICK, M. J., MINNERATH, S. R., LIN, X., ELDE, R., LAW, P.-Y. AND LOH, H. H.: Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned μ, δ, and kappa opioid receptors. Mol. Brain Res. 27: 37-44, 1994.
47. Xu, X.-J., Hao, J.-X. and Wiesenfeld-Hallin, Z.: Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat. Soc. Neurosci. 22: 1368, 1996.(Abstract).
48. YASUDA, K., RAYNOR, K., KONG, H., BREDER, C., TAKEDA, J., REISINE, T. AND BELL, G. CLONING AND FUNCTIONAL COMPARISON OF KAPPA AND Δ.: opioid receptors from mouse brain. Proc. Natl. Acad. Sci. U.S.A. 90: 6736-6740, 1993.
49. ZIMPRICH, A., BACHER, B. AND HÖLLT, V.: Cloning and expression of an isoform of the rmu-opioid receptor (μOR-1B). Regul. Pept. 54: 347-348, 1994.